• 여성건강간호학회지
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• 제24권3호
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• pp.297-309
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• 2018

Purpose: To develop Pregnancy Risk symptom Perception Scale (PRPS) and evaluate its validity and reliability. Methods: A preliminary 30-item version of PRPS was developed through literature review, in-depth interview, and Content Validity. Each item was scored on a four-point Likert scale. The preliminary scale was developed based on 301 pregnant women who visited a hospital. Date were analyzed using item analysis, factor analysis, confirmatory factor analysis, Pearson's correlation coefficients, and Cronbach's ${\alpha}$ (0.90 for total item, 0.80 to 0.88 for factors). Results: The PRPS consisted of 27 items. Three factors (physical, environmental, and emotional factors) explained 55% of the total variance. Cronbach's Criterion validity was supported by comparison with the Perception of Pregnancy Risk Questionnaire (r=0.34). In reliability test, the reliability coefficient of pregnancy risk symptom perception was high at 0.90. Conclusion: These results suggest that the pregnancy risk symptom perception scale developed in this study comprises items that can assess the level of pregnant women's pregnancy risk symptom perception in Korea. Its validity and reliability were proven. PRPS can be utilized to measure pregnant women's risk symptom perception during pregnancy. PRPS will contribute to the development of systematic prenatal care and effective risk management.

• 생물정신의학
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• 제21권3호
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• pp.87-92
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• 2014

Objectives Risk taking has been implicated in the development of various psychiatric disorders. Previous studies have indicated that risk taking behavior is associated with high levels of impulsiveness. Risk taking entail uncertain situation that outcome probability is unknown. This study tested impulsivity, intolerance of uncertainty and risk taking behavior. Methods A total of 73 participants completed a test battery comprised of the UPPS-P scale as a psychometric measurement of five dimensions of impulsivity, Intolerance of Uncertainty Scale, and Balloon Analog Risk Task (BART) as a behavioral measure of risk taking. The Pearson correlation analysis was used. Results The sensation seeking factor was positively correlated with BART measure (r = 0.27, p = 0.02). Specifically, the relationship between sensation seeking and BART was significant in females. Conclusions Among the five factors of UPPS-P, only the sensation seeking factor predicts risk taking propensity.

• 한국터널지하공간학회 논문집
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• 제9권1호
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• pp.63-74
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• 2007

불확실한 지반의 상태는 항상 터널 건설에 있어서 많은 문제점을 일으킨다. 그러므로 새로운 터널의 건설에 앞서 위험에 대한 평가가 필요하다. 이 논문은 수정된 안정계수를 이용한 간편 위험도 평가 시스템인 URI(Underground Risk Index)를 제안하였다. URI의 평가요소들은 각 요소의 등급에 따라 점수화하여 분석함으로서 설계단계에서 위험 가능성에 대한 평가에 이용이 가능하도록 하였으며, 기존의 Interaction Matrix에서 8개의 설계 요소 중(RQD, 일축압축강도, 풍화도, 안정계수, 토피고, 지하수위, RMR, 투수계수)안정계수 산정방법을 수정하여 보다 신뢰성을 높였다. 또한 현장적용에 대한 신뢰성을 검증하기위하여 URI 시스템을 실제현장에 적용하였다.

• 성인간호학회지
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• 제21권3호
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• pp.314-323
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• 2009

Purpose: This descriptive study was conducted to identify the level of knowledge of stroke symptoms and risk factors among older adults. Methods: A total of 200 older adults over 65 years of age were conveniently recruited from out patient departments of two hospitals and a health care center from October to November 2008. The level of knowledge was assessed using both open-ended questions and a structured questionnaire based on semi-structured interviews. Data were analyzed by t-tests and ANOVA using the SPSS program. Results: 52.5% of the sample had hypertension and 30% had diabetes. The mean knowledge scores for symptoms and risk factors were $8.4{\pm}3.1$ (out of 15) and $9.5{\pm}3.9$ (out of 16), respectively. The older adults who had lower education, lower family income, and who lived in rural areas were more likely to have less knowledge of stroke symptom and risk factors (p < .05). There was no significant knowledge difference between the older adults who had at least one risk factor and those who had no risk factor for stroke. Conclusions: Educational intervention should be focused on informing older adults who are at risk for stroke about the early symptoms and management of risk factors, especially those who have low education and low social status.

• 한국물환경학회지
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• 제25권4호
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• pp.494-501
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• 2009

Probabilistic Ecological risk assessment (PERA) is extensive approach to qualify and quantify risk on the multi species based on species sensitivity distribution (SSD). As a while, deterministic ecological risk assessment (DERA) considers the comparison of predicted no-effect concentration (PNEC) and predicted exposure concentration (PEC). DERA is used to determine if there is potential risk or no risk, and it doesn't consider the nature variability and the species sensitivity. But PERA can be more realistic and reasonable approach to estimate likelihood or risk. In this study, we compared PERA used in developed countries, and proposed PERA applicable for the Korean water environment. Taxonomic groups were classified as "class" level including Actinopterygill, Branchiopoda, Chlorophyceae, Maxillapoda, Insects, Bivalvia, Gastropoda, Secernentea, Polychaeta, Monocotyldoneae, and Chanophyceae in this study. Statistical extrapolation method (SEM), statistical extrapolation method $_{acutechronicratio}$ ($SEM_{ACR}$) and assessment factor method (AFM) were used to calculate the ecological protective concentration based on qualitative and quantitative levels of taxonomic toxicity data. This study would be useful to establish the PERA for the protection of aquatic ecosystem in Korea.

• Journal of Gastric Cancer
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• 제16권1호
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• pp.43-50
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• 2016

Purpose: It is well known that old age is a risk factor for postoperative complications. Therefore, this study aimed to explore the risk factors for poor postoperative surgical outcomes in elderly gastric cancer patients. Materials and Methods: Between January 2006 and December 2015, 247 elderly gastric cancer patients who underwent curative gastrectomy were reviewed. In this study, an elderly patient was defined as a patient aged ${\geq}65$ years. All possible variables were used to explore the risk factors for poor early surgical outcomes in elderly gastric cancer patients. Results: Based on multivariate analyses of preoperative risk factors, preoperative low serum albumin level (<3.5 g/dl) and male sex showed statistical significance in predicting severe postoperative complications. Additionally, in an analysis of surgery-related risk factors, total gastrectomy was a risk factor for severe postoperative complications. Conclusions: Our study findings suggest that low serum albumin level, male sex, and total gastrectomy could be risk factors of severe postoperative complications in elderly gastric cancer patients. Therefore, surgeons should work carefully in cases of elderly gastric cancer patients with low preoperative serum albumin level and male sex. We believe that efforts should be made to avoid total gastrectomy in elderly gastric cancer patients.

• 시큐리티연구
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• 제48호
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• pp.177-206
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• 2016

이 연구의 목적은 위험해석모형을 적용하여 범죄두려움의 영향요인을 검증하는 데 있다. 특히, 기존의 연구들이 위험해석모형에서 제시된 미시적 개인요소를 포함하지 않고 있어 이 연구에서는 미시적 개인요소, 지역사회요소, 범죄 위험의 인지, 범죄두려움 등을 주요 변인으로 포함하였다. 이 연구에 사용된 자료는 형사정책연구원(2012)에서 실시한 '전국범죄피해조사'의 2차 자료를 활용하였으며, 해당 변인들이 범죄두려움에 미치는 개별적인 영향력을 검증하고, 위험해석모형에서 제시된 인과적 경로관계를 규명하기 위해 2단계의 다중회귀분석과 Sobel Test를 실시하였다. 분석결과, 범죄 위험의 인지가 높을수록, 여성일수록, 지역사회가 무질서하다고 인식할수록, 연령이 낮을수록, 범죄피해를 경험할수록, 학력이 높을수록, 소득수준이 높을수록 범죄두려움을 보다 많이 인식하고 있었으며, 그리고 위험해석모형에서 제시된 인과적 경로관계는 학력을 제외하고 모두 유의미하게 제시되었다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권17호
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• pp.7407-7411
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• 2014

The incidence of urban female breast cancer has been continuously increasing over the past decade with unknown etiology. One hypothesis for this increase is carcinogen exposure from tobacco. Therefore, the objective of this study was to investigate the risk of urban female breast cancer from tobacco smoke exposure. The matched case control study was conducted among Thai females, aged 17-76 years and living in Bangkok or its surrounding areas. A total of 444 pairs of cases and controls were recruited from the Thai National Cancer Institute. Cases were newly diagnosed and histologically confirmed as breast cancer while controls were selected from healthy women who visited a patient, matched by age ${\pm}5$ years. After obtaining informed consent, tobacco smoke exposure data and information on other potential risk factors were collected by interview. The analysis was performed by conditional logistic regression, and presented with odds ratio (ORs) and 95% confidence intervals(CI). From all subjects, 3.8% of cases and 3.4% of controls were active smokers while 11.0% of cases and 6.1% of controls were passive smokers. The highest to lowest sources of passive tobacco smoke were from spouses (40.8%), the workplace (36.8%) and public areas (26.3%), respectively. After adjusting for other potential risk factors or confounders, females with frequent low-dose passive smoke exposure (${\leq}7$ hours per week) from a spouse or workplace had adjusted odds ratio 3.77 (95%CI=1.11-12.82) and 4.02 (95%CI=1.04-15.50) higher risk of breast cancer compared with non-smokers, respectively. However, this study did not find any association of breast cancer risk in high dose passive tobacco smoke exposure, or a dose response relationship in cumulative passive tobacco smoke exposure per week, or in the active smoker group. In conclusion, passive smoke exposure may be one important risk factor of urban female breast cancer, particularly, from a spouse or workplace. This risk factor highlights the importance of avoiding tobacco smoke exposure as a key measure for breast cancer prevention and control.

• 디지털융복합연구
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• 제16권2호
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• pp.421-430
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• 2018

본 연구에서는 대구지역의 사춘기청소년을 대상으로 건강위험행동에 대한 척도기준을 분석하는 데 있다. 연구방범은 우리나라 사춘기청소년의 건강특성에 맞는 건강위험행동 측정항목을 개발하고자, 기존 THI의 측정항목에 대한 내용 타당성(CVR)분석을 하고, 이후 확인적 요인분석을 통하여 구체화 한 건강위험행동의 척도를 비교 분석하였다. 분석결과, 요인분석을 통해 개발된 사춘기청소년들의 건강위험행동 척도에 대한 신뢰도 검증을 실시하여 전신상태, 호흡기, 순환기, 소화기, 정신건강 기타항목 등의 측정항목을 도출하였다. 개발된 건강위험행동 척도의 신뢰도와 타당도는 상당히 양호한 것으로 나타났다. 이러한 연구를 통해서 사춘기청소년들의 건강과 관련된 위험행동을 감소시킬 수 있는 예방프로그램을 개발하고, 정책수립에 기초적인 자료를 제공할 수 있는 전략을 고안해 낼 수 있을 것이다.

• 약학회지
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• 제55권4호
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• pp.352-360
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• 2011

Standard combination chemotherapy including isoniazid, rifampin, pyrazinamide, and ethambutol is very effective against tuberculosis. But, these medicines can cause hepatotoxicity which is the main reason for treatment interruption or change in drug regimen. In order to identify risk factors associated with hepatotoxcity in Koreans and assess elevated baseline LFTs' contributions to hepatotoxicity, a retrospective case control study was performed. The medical records of 277 patients who diagnosed with tuberculosis at a community hospital from January 1st, 2007 to June 30th, 2010 were reviewed. Patients were categorized into 3 groups (non toxic group, patients without increase in LFT levels; mild to moderate hepatotoxic group and severe hepatotoxic group). And the correlation between risk factors and hepatotoxicity was analyzed by using SPSS program. The overall incidence of hepatotoxicity was 18% and 8.7% of patients developed severe toxicity. Patients in the severe toxic group had the longest treatment period among the three groups. In 75% of severe toxic group, hepatotoxicity occurred within 18.3 days after starting medication. Hypoalbuminemia (serum albumin <3 g/dl) was a significant risk factor for development of severe toxicity. Elevated baseline transaminase (except ALT), total bilirubin, and preexisting hepatitis were also risk factors which were more than twice as likely to increase risk of severe hepatotoxicity (p>0.05). In conclusion, hypoalbuminemia (serum albumin level <3 g/dl) was a significant risk factor for anti-tuberculosis druginduced severe toxicity. Therefore, before starting antituberculosis chemotherapy, serum albumin level should be assessed at baseline. In high-risk patients (hypoalbuminemia, elevated LFTs) for hepatotoxicty, liver function should be closely monitored up to at least 21 days after taking medication.