• Toxicological Research
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• v.13 no.4
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• pp.377-383
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• 1997

To investigate the circadian variation in the bromobenzene metabolism, bromobenzene(400 mg/kg body weight) was intraperitoneally administered to the rats every other day for 6 days both in the night; 24:00 and the day; 12:00. Each group of animals was sacrificed at 8hr after last injection of bromobenzene. The contents of hepatic CYP were more increased in control rats of night phase than those of day phase but in case of bromobenzene treatment there were no differences in hepatic CYP between rats of the night phase and those of day phase and the injection of prednisolon inhibited the hepatic CYP content in rats. Furthermore, the decreasing rate of hepatic glutathione contents to the control was higher in rats of day phase than those of night phase by the bromobenzene treatment. And the hepatic glutathione S-transferase activities were increased both in control and bromobenzene treated rats of the night phase than those of day phase. On the other hand, liver weight per body weight(%), hepatic lipid peroxide content, serum levels of alanine aminotransferase were more increased both in bromobenzene-treated and control rats of the night phase than those in the day phase. These results indicate that the rats of night phase may induce more accelerated formation of bromobenzene 3,4-oxide from bromobezene than those of day phase in rats.

• Child Health Nursing Research
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• v.14 no.3
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• pp.315-324
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• 2008

Purpose: This study was done to determine the effects of a neurofeedback program on brain function and stress in occupational high school students. Method: A nonequivalent control group, non-synchronized with pre-posttest design was used with 62 students. Data collection was done from July to December, 2007. The neurofeedback training was given for 30 minutes at a time, three times a week for 12 weeks. Brain function was measured by brain waves in the frontal lobes of the students and analyzed by eight brain quotients characterizing patterns of EEG rhythms. The instrument used to measure stress was a scale for stress from regular daily life. Results: After neurofeedback training, the level of brain quotients in students in the experiment group increased(t=2.36, p<.05) and the level of stress decreased(t=-3.59, p<.001). Conclusion: The results of the study suggested that a neurofeedback program is effective for brain function improvement and stress reduction in high school students. Therefore, the conclusion of this study is that neurofeedback programs can be useful to increase brain function and decrease stress in occupational high school students.

• Journal of Digital Contents Society
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• v.11 no.1
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• pp.9-16
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• 2010

Recently, needs and interests that people want to create their digital contents in ubiquitous environment are growing fast. Among the digital contents, people are also interested in the music contents. However, it is hard to find a system which manages and shares music contents easily. The paper proposes a system that provides a composition function for music, a mixing function for music, and a function for ear training. The contributions of the paper are as follows. First, the paper provides a music management system which enables music compositions, listening function of music, searching functionalities. Second, the paper introduces a function of mixing drum sound for managing rhythms. Third, the paper provides game contents which improve senses of music. The proposed system is expected that enables users composite music in ubiquitous environment, provides rich functions for compositions, and improves senses of music.

• Molecules and Cells
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• v.43 no.8
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• pp.671-685
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• 2020

The regulator of calcineurin (RCAN) was first reported as a novel gene called DSCR1, encoded in a region termed the Down syndrome critical region (DSCR) of human chromosome 21. Genome sequence comparisons across species using bioinformatics revealed three members of the RCAN gene family, RCAN1, RCAN2, and RCAN3, present in most jawed vertebrates, with one member observed in most invertebrates and fungi. RCAN is most highly expressed in brain and striated muscles, but expression has been reported in many other tissues, as well, including the heart and kidneys. Expression levels of RCAN homologs are responsive to external stressors such as reactive oxygen species, Ca²⁺, amyloid β, and hormonal changes and upregulated in pathological conditions, including Alzheimer's disease, cardiac hypertrophy, diabetes, and degenerative neuropathy. RCAN binding to calcineurin, a Ca²⁺/calmodulin-dependent phosphatase, inhibits calcineurin activity, thereby regulating different physiological events via dephosphorylation of important substrates. Novel functions of RCANs have recently emerged, indicating involvement in mitochondria homeostasis, RNA binding, circadian rhythms, obesity, and thermogenesis, some of which are calcineurin-independent. These developments suggest that besides significant contributions to DS pathologies and calcineurin regulation, RCAN is an important participant across physiological systems, suggesting it as a favorable therapeutic target.

• The Journal of the Korea Contents Association
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• v.18 no.6
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• pp.617-627
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• 2018

Baroque music was the birth and growth era of modern music, but it was not composed for movies. Baroque music, however, is a feature that is inserted into the movies in many different forms, leading to the overall mood and narrative, and the ability to express the characters' feeling and inner word. Therefore, in this study, five Baroque music works, including the main theme song 'Vivaldi Cantata RV.684' in the movie , are produced, and analyzed through tonal, tempo, dynamics, musical notes, tones, rhythms, musical instrument, and genre. Through analysis, we will study what epic functions and roles Baroque music plays in movies.

• Journal of IKEEE
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• v.24 no.1
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• pp.254-259
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• 2020

This paper is the implementation of the conversion system from image to music based on intentional synesthesia. The input image based on color, texture, and shape was converted into melodies, harmonies and rhythms of music, respectively. Depending on the histogram of colors, the melody can be selected and obtained probabilistically to form the melody. The texture in the image expressed harmony and minor key with 7 characteristics of GLCM, a statistical texture feature extraction method. Finally, the shape of the image was extracted from the edge image, and using Hough Transform, a frequency component analysis, the line components were detected to produce music by selecting the rhythm according to the distribution of angles.

• Korean Journal of Agricultural Science
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• v.44 no.3
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• pp.309-317
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• 2017

Melatonin (N-acetyl-5-methoxytryptamine) is an indole synthesized from tryptophan by the pineal gland in animal. The major function of melatonin is to modulate circadian and circannual rhythms in photoperiodic mammals. Importantly, however, melatonin is also a free radical scavenger, anti-oxidant, and anti-apoptotic agent. Recently, the beneficial effects of melatonin on oocyte maturation and embryonic development in vitro have been reported in many species such as pig, cattle, sheep, mouse, and human. In this review, we will discuss recent studies about the role of melatonin in the production of porcine and bovine oocytes and embryos in vitro in order to provide useful information of melatonin in oocyte maturation and embryo culture in vitro.

• Journal of the Ergonomics Society of Korea
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• v.19 no.3
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• pp.1-12
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• 2000

The Korean version of the morningness-eveningness questionnaire (MEQ) and sleep habits inventory were administered to 1,038 Korean male daytime workers and were analyzed according to age and chronotype to determine what these factors reveal about sleep habits in view of phase difference of circadian rhythm. The mean and distribution of scores on the MEQ moved significantly toward the morning type with aging. Bedtimes and waking times were progressively later from the morning, intermediate, to evening types, and were also earlier with aging. Preferred bedtimes and waking times showed more distinct differences than did the habitual times in each chronotype. The percentage of subjects who answered that sleep length was 'short', mood upon waking was 'bad', and variabilities of bedtime and sleep length were 'large' were greater in the young and evening types than in the elder and morning types, respectively. These findings suggested that subjects were shifted toward the morning type and the phase of circadian rhythm had moved forward with aging. Preferred bedtime and waking time were a better reflection of individual circadian rhythms than habitual bedtime and waking time.

• BMB Reports
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• v.50 no.5
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• pp.235-236
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• 2017

The circadian clock is an internal system that is synchronized by external stimuli, such as light and temperature, and influences various physiological and developmental processes in living organisms. In the model plant Arabidopsis, transcriptional, translational and post-translational processes are interlocked by feedback loops among morning- and evening-phased genes. In a post-translational loop, plant-specific single-gene encoded GIGANTEA (GI) stabilize the F-box protein ZEITLUPE (ZTL), driving the targeted-proteasomal degradation of TIMING OF CAB EXPRESSION 1 (TOC1) and PSEUDO-RESPONSE REGULATOR 5 (PRR5). Inherent to this, we demonstrate the novel biochemical function of GI as a chaperone and/or co-chaperone of Heat-Shock Protein 90 (HSP90). GI prevents ZTL degradation as a chaperone and facilitates ZTL maturation together with HSP90/HSP70, enhancing ZTL activity in vitro and in planta. GI is known to be involved in a wide range of physiology and development as well as abiotic stress responses in plants, but it could also interact with diverse client proteins to increase protein maturation. Our results provide evidence that GI helps proteostasis of ZTL by acting as a chaperone and a co-chaperone of HSP90 for proper functioning of the Arabidopsis circadian clock.

• Fashion & Textile Research Journal
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• v.17 no.2
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• pp.178-190
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• 2015

The purpose of this study is to analyze the formative characteristics of animal stripes based on the colors, shapes and texture through classification standards under functional meanings, and it also aims to produce various stripe patterns based on its outcome to develop modern fashion design. For the study method, specialty publications, preceding researches and internet websites were utilized for the purpose of theoretical discussion on animal stripes. And it is also to examine functional meanings formed by animal stripes in order to analyze the characteristics of stripes; subsequently, based on the classification standard of this function, it is to identify the distinction of its colors through quantitative analysis on formative characteristics and colors. By using the following analyzed color palette of stripes, various stripe patterns were developed and designed with the sense of modern fashion while repeatedly using the shape with systematic colors and rhythms displayed on the animals. As a result of this study, it was confirmed that animal stripes possess a regularity that is systematic and can be digitized. After identifying, analyzing and systemizing formative characteristics of animal stripes, a concept of division and competition was applied; subsequently, whole new stripe patterns were developed and designed in order to further promote fashion design.