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http://dx.doi.org/10.7744/kjoas.20170050

The influence and role of melatonin on in vitro oocyte maturation and embryonic development in pig and cattle  

Lin, Tao (Division of Animal Science, Research Center for Transgenic Cloned Pigs, Chungnam National University)
Lee, Jae Eun (Division of Animal Science, Research Center for Transgenic Cloned Pigs, Chungnam National University)
Kang, Jeong Won (Division of Animal Science, Research Center for Transgenic Cloned Pigs, Chungnam National University)
Kim, So Yeon (Division of Animal Science, Research Center for Transgenic Cloned Pigs, Chungnam National University)
Jin, Dong Il (Division of Animal Science, Research Center for Transgenic Cloned Pigs, Chungnam National University)
Publication Information
Korean Journal of Agricultural Science / v.44, no.3, 2017 , pp. 309-317 More about this Journal
Abstract
Melatonin (N-acetyl-5-methoxytryptamine) is an indole synthesized from tryptophan by the pineal gland in animal. The major function of melatonin is to modulate circadian and circannual rhythms in photoperiodic mammals. Importantly, however, melatonin is also a free radical scavenger, anti-oxidant, and anti-apoptotic agent. Recently, the beneficial effects of melatonin on oocyte maturation and embryonic development in vitro have been reported in many species such as pig, cattle, sheep, mouse, and human. In this review, we will discuss recent studies about the role of melatonin in the production of porcine and bovine oocytes and embryos in vitro in order to provide useful information of melatonin in oocyte maturation and embryo culture in vitro.
Keywords
apoptosis; embryo development; ER stress; melatonin; oocyte maturation; ROS;
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1 Abecia JA, Forcada F, Zuniga O. 2002. The effect of melatonin on the secretion of progesterone in sheep and on the development of ovine embryos in vitro. Veterinary Research Communications 26:151-158.   DOI
2 Agarwal A, Saleh RA, Bedaiwy MA. 2003. Role of reactive oxygen species in the pathophysiology of human reproduction. Fertility and Sterility 79:829-843.   DOI
3 Arendt J. 1998. Melatonin and the pineal gland: Influence on mammalian seasonal and circadian physiology. Reviews of Reproduction 3:13-22.   DOI
4 Barrett P, Bolborea M. 2012. Molecular pathways involved in seasonal body weight and reproductive responses governed by melatonin. Journal of Pineal Research 52:376-388.   DOI
5 Chen Z, Zuo X, Li H, Hong R, Ding B, Liu C, Gao D, Shang H, Cao Z, Huang W, Zhang X, Zhang Y. 2017. Effects of melatonin on maturation, histone acetylation, autophagy of porcine oocytes and subsequent embryonic development. Animal Science Journal 88:1298-1310.   DOI
6 Hardeland R. 2005. Antioxidative protection by melatonin: Multiplicity of mechanisms from radical detoxification to radical avoidance. Endocrine 27:119-130.   DOI
7 Hoffman RA, Reiter RJ. 1965. Pineal gland: Influence on gonads of male hamsters. Science 148:1609-1611.   DOI
8 Hwang IS, Hara H, Chung HJ, Hirabayashi M, Hochi S. 2013. Rescue of vitrified-warmed bovine oocytes with rho-associated coiled-coil kinase inhibitor. Biology of Reproduction 89:26.
9 Jardine DS. 2007. Heat illness and heat stroke. Pediatrics in Review 28:249-258.   DOI
10 Kang JT, Koo OJ, Kwon DK, Park HJ, Jang G, Kang SK, Lee BC. 2009. Effects of melatonin on in vitro maturation of porcine oocyte and expression of melatonin receptor RNA in cumulus and granulosa cells. Journal of Pineal Research 46:22-28.   DOI
11 Latham KE. 2015. Endoplasmic reticulum stress signaling in mammalian oocytes and embryos: Life in balance. International Review of Cell and Molecular Biology 316:227-265.
12 Li Y, Wang J, Zhang Z, Yi J, He C, Wang F, Tian X, Yang M, Song Y, He P, Liu G. 2016. Resveratrol compares with melatonin in improving in vitro porcine oocyte maturation under heat stress. Journal of Animal Science and Biotechnology 7:33.   DOI
13 Li Y, Zhang Z, He C, Zhu K, Xu Z, Ma T, Tao J, Liu G. 2015. Melatonin protects porcine oocyte in vitro maturation from heat stress. Journal of Pineal Research 59:365-375.   DOI
14 Liang S, Guo J, Choi JW, Kim NH, Cui XS. 2016. Effect and possible mechanisms of melatonin treatment on the quality and developmental potential of aged bovine oocytes. Reproduction Fertility and Development 29:1821-1831.
15 Tian X, Wang F, He C, Zhang L, Tan D, Reiter RJ, Xu J, Ji P, Liu G. 2014. Beneficial effects of melatonin on bovine oocytes maturation: A mechanistic approach. Journal of Pineal Research 57:239-247.   DOI
16 Mehaisen GM, Saeed AM, Gad A, Abass AO, Arafa M, El-Sayed A. 2015. Antioxidant capacity of melatonin on preimplantation development of fresh and vitrified rabbit embryos: Morphological and molecular aspects. Plos One 10:e0139814.   DOI
17 Morato R, Izquierdo D, Paramio MT, Mogas T. 2010. Survival and apoptosis rates after vitrification in cryotop devices of in vitro-produced calf and cow blastocysts at different developmental stages. Reproduction Fertility and Development 22:1141-1147.   DOI
18 Nagina G, Asima A, Nemat U, Shamim A. 2016. Effect of melatonin on maturation capacity and fertilization of Nili-Ravi buffalo (Bubalus bubalis) oocytes. Open Veterinary Journal 6:128-134.   DOI
19 Shi JM, Tian XZ, Zhou GB, Wang L, Gao C, Zhu SE, Zeng SM, Tian JH, Liu GS. 2009. Melatonin exists in porcine follicular fluid and improves in vitro maturation and parthenogenetic development of porcine oocytes. Journal of Pineal Research 47:318-323.   DOI
20 Tamura H, Takasaki A, Taketani T, Tanabe M, Kizuka F, Lee L, Tamura I, Maekawa R, Asada H, Yamagata Y. 2013. Melatonin as a free radical scavenger in the ovarian follicle. Endocrine Journal 60:1-13.   DOI
21 Tian XZ, Wen Q, Shi JM, Liang W, Zeng SM, Tian JH, Zhou GB, Zhu SE, Liu GS. 2010. Effects of melatonin on in vitro development of mouse two-cell embryos cultured in HTF medium. Endocrine Research 35:17-23.   DOI
22 Utaipan T, Athipornchai A, Suksamrarn A, Chunsrivirot S, Chunglok W. 2017. Isomahanine induces endoplasmic reticulum stress and simultaneously triggers p38 MAPK-mediated apoptosis and autophagy in multidrugresistant human oral squamous cell carcinoma cells. Oncology Reports 37:1243-1252.   DOI
23 Vallorani C, Spinaci M, Bucci D, Porcu E, Tamanini C, Galeati G. 2012. Pig oocyte vitrification by cryotop method and the activation of the apoptotic cascade. Animal Reproduction Science 135:68-74.   DOI
24 Wang F, Tian X, Zhou Y, Tan D, Zhu S, Dai Y, Liu G. 2014. Melatonin improves the quality of in vitro produced (IVP) bovine embryos: implications for blastocyst development, cryotolerance, and modifications of relevant gene expression. Plos One 9:e93641.   DOI
25 Yuan Y, Hao ZD, Liu J, Wu Y, Yang L, Liu GS, Tian JH, Zhu SE, Zeng SM. 2008. Heat shock at the germinal vesicle breakdown stage induces apoptosis in surrounding cumulus cells and reduces maturation rates of porcine oocytes in vitro. Theriogenology 70:168-178.   DOI
26 Wang JZ, Sui HS, Miao DQ, Liu N, Zhou P, Ge L, Tan JH. 2009. Effects of heat stress during in vitro maturation on cytoplasmic versus nuclear components of mouse oocytes. Reproduction 137:181-189.   DOI
27 Wang X, Falcone T, Attaran M, Goldberg JM, Agarwal A, Sharma RK. 2002. Vitamin C and vitamin E supplementation reduce oxidative stress-induced embryo toxicity and improve the blastocyst development rate. Fertility and Sterility 78:1272-1277.   DOI
28 Yorimitsu T, Nair U, Yang Z, Klionsky DJ. 2006. Endoplasmic reticulum stress triggers autophagy. Journal of Biological Chemistry 281:30299-30304.   DOI
29 Zarazaga LA, Celi I, Guzman JL, Malpaux B. 2010. Melatonin concentrations in the two jugular veins, and relationship with the seasonal reproductive activity in goats. Theriogenology 74:221-228.   DOI
30 Zhang JY, Diao YF, Oqani RK, Han RX, Jin DI. 2012. Effect of endoplasmic reticulum stress on porcine oocyte maturation and parthenogenetic embryonic development in vitro. Biology of Reproduction 86:128.
31 Zhao XM, Hao HS, Du WH, Zhao SJ, Wang HY, Wang N, Wang D, Liu Y, Qin T, Zhu HB. 2016. Melatonin inhibits apoptosis and improves the developmental potential of vitrified bovine oocytes. Journal of Pineal Research 60:132-141.   DOI
32 Zhao XM, Min JT, Du WH, Hao HS, Liu Y, Qin T, Wang D, Zhu HB. 2015. Melatonin enhances the in vitro maturation and developmental potential of bovine oocytes denuded of the cumulus oophorus. Zygote 23:525-536.   DOI
33 Do LT, Shibata Y, Taniguchi M, Nii M, Nguyen TV, Tanihara F, Takagi M, Otoi T. 2015. Melatonin supplementation during in vitro maturation and development supports the development of porcine embryos. Reproduction in Domestic Animals 50:1054-1058.   DOI
34 Ciechomska IA, Gabrusiewicz K, Szczepankiewicz AA, Kaminska B. 2013. Endoplasmic reticulum stress triggers autophagy in malignant glioma cells undergoing cyclosporine a-induced cell death. Oncogene 32:1518-1529.   DOI
35 Cruz MH, Leal CL, da Cruz JF, Tan DX, Reiter RJ. 2014. Role of melatonin on production and preservation of gametes and embryos: A brief review. Animal Reproduction Science 145:150-160.   DOI
36 Dair EL, Simoes RS, Simoes MJ, Romeu LR, Oliveira-Filho RM, Haidar MA, Baracat EC, Soares JM, Jr. 2008. Effects of melatonin on the endometrial morphology and embryo implantation in rats. Fertility and Sterility 89:1299-1305.   DOI
37 El-Raey M, Geshi M, Somfai T, Kaneda M, Hirako M, Abdel-Ghaffar AE, Sosa GA, El-Roos ME, Nagai T. 2011. Evidence of melatonin synthesis in the cumulus oocyte complexes and its role in enhancing oocyte maturation in vitro in cattle. Molecular Reproduction and Development 78:250-262.   DOI
38 Fan L, Sun G, Ma T, Zhong F, Lei Y, Li X, Wei W. 2013. Melatonin reverses tunicamycin-induced endoplasmic reticulum stress in human hepatocellular carcinoma cells and improves cytotoxic response to doxorubicin by increasing CHOP and decreasing survivin. Journal of Pineal Research 55:184-194.   DOI
39 Hadj Ayed Tka K, Mahfoudh Boussaid A, Zaouali MA, Kammoun R, Bejaoui M, Ghoul Mazgar S, Rosello Catafau J, Ben Abdennebi H. 2015. Melatonin modulates endoplasmic reticulum stress and Akt/GSK3-beta signaling pathway in a rat model of renal warm ischemia reperfusion. Analytical Cellular Pathology 2015: Article ID 635172, 1-10.
40 Lin T, Lee JE, Oqani RK, Kim SY, Cho ES, Jeong YD, Baek JJ, Jin DI. 2016b. Tauroursodeoxycholic acid improves pre-implantation development of porcine SCNT embryo by endoplasmic reticulum stress inhibition. Reproductive Biology 16:269-278.   DOI
41 Lin T, Lee JE, Shin HY, Oqani RK, Kim SY, Jin DI. 2016a. Supplement of tauroursodeoxycholic acid in vitrification solution improves the development of mouse embryos. Korean Journal of Agricultural Science 43:575-580.
42 Manjunatha BM, Devaraj M, Gupta PS, Ravindra JP, Nandi S. 2009. Effect of taurine and melatonin in the culture medium on buffalo in vitro embryo development. Reproduction in Domestic Animals 44:12-16.   DOI
43 Mehaisen GM, Saeed AM. 2015. In vitro development rate of preimplantation rabbit embryos cultured with different levels of melatonin. Zygote 23: 111-115.   DOI
44 Rodrigues-Cunha MC, Mesquita LG, Bressan F, Collado MD, Balieiro JC, Schwarz KR, de Castro FC, Watanabe OY, Watanabe YF, de Alencar Coelho L, Leal CL. 2016. Effects of melatonin during IVM in defined medium on oocyte meiosis, oxidative stress, and subsequent embryo development. Theriogenology 86:1685-1694.   DOI
45 Nakano M, Kato Y, Tsunoda Y. 2012. Effect of melatonin treatment on the developmental potential of parthenogenetic and somatic cell nuclear-transferred porcine oocytes in vitro. Zygote 20:199-207.   DOI
46 Park JY, Park HJ, Kim JW, Park SY, Yang SG, Jung JM, Kim MJ, Koo DB. 2017. Melatonin alleviates the endoplasmic reticulum stress through the regulating of unfolding protein response signaling during porcine oocyte maturation in vitro. Reproduction, Fertility and Development 29:195-195.
47 Quan XJ, Wang JY, Liang CL, Zheng HD, Zhang L. 2015. Melatonin inhibits tunicamycin-induced endoplasmic reticulum stress and insulin resistance in skeletal muscle cells. Biochemical and Biophysical Research Communications 463:1102-1107.   DOI
48 Rodriguez C, Mayo JC, Sainz RM, Antolin I, Herrera F, Martin V, Reiter RJ. 2004. Regulation of antioxidant enzymes: A significant role for melatonin. Journal of Pineal Research 36:1-9.   DOI
49 Sharma S, Sarkar J, Haldar C, Sinha S. 2014. Melatonin reverses Fas, E2F-1 and endoplasmic reticulum stress mediated apoptosis and dysregulation of autophagy induced by the herbicide atrazine in murine splenocytes. Plos One 9:e108602.   DOI