• Title/Summary/Keyword: rhoA

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ON DISTANCE-PRESERVING MAPPINGS

  • Jung, Soon-Mo;M.Rassias, Themistocles
    • Journal of the Korean Mathematical Society
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    • v.41 no.4
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    • pp.667-680
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    • 2004
  • We generalize a theorem of W. Benz by proving the following result: Let $H_{\theta}$ be a half space of a real Hilbert space with dimension $\geq$ 3 and let Y be a real normed space which is strictly convex. If a distance $\rho$ > 0 is contractive and another distance N$\rho$ (N $\geq$ 2) is extensive by a mapping f : $H_{\theta}$ \longrightarrow Y, then the restriction f│$_{\theta}$ $H_{+}$$\rho$/2// is an isometry, where $H_{\theta}$$\rho$/2/ is also a half space which is a proper subset of $H_{\theta}$. Applying the above result, we also generalize a classical theorem of Beckman and Quarles.

A NOTE ON OPERATORS ON FINSLER MODULES

  • TAGHAVI, A.;JAFARZADEH, JAFARZADEH
    • Honam Mathematical Journal
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    • v.28 no.4
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    • pp.533-541
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    • 2006
  • let E be a Finsler modules over $C^*$-algebras. A with norm-map $\rho$ and L(E) set of all A-linear bonded operators on E. We show that the canonical homomorphism ${\phi}:L(E){\rightarrow}L(E_I)$ sending each operator T to its restriction $T|E_I$ is injective if and only if I is an essential ideal in the underlying $C^*$-algebra A. We also show that $T{\in}L(E)$ is a bounded below if and only if ${\mid}{\mid}x{\mid}{\mid}={\mid}{\mid}{\rho}{\prime}(x){\mid}{\mid}$ is complete, where ${\rho}{\prime}(x)={\rho}(Tx)$ for all $x{\in}E$. Also, we give a necessary and sufficient condition for the equivalence of the norms generated by the norm map.

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SEMIGROUP PRESENTATIONS FOR CONGRUENCES ON GROUPS

  • Ayik, Gonca;Caliskan, Basri
    • Bulletin of the Korean Mathematical Society
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    • v.50 no.2
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    • pp.445-449
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    • 2013
  • We consider a congruence ${\rho}$ on a group G as a subsemigroup of the direct product $G{\times}G$. It is well known that a relation ${\rho}$ on G is a congruence if and only if there exists a normal subgroup N of G such that ${\rho}=\{(s,\;t):st^{-1}{\in}N\}$. In this paper we prove that if G is a finitely presented group, and if N is a normal subgroup of G with finite index, then the congruence ${\rho}=\{(s,\;t):st^{-1}{\in}N\}$ on G is finitely presented.

Efficacy of Recombinant Human Erythropoietin(rhu-EPO)

  • Kim, Dong-Hwan;Ahn, Byoung-Ok;Park, Jang-Hyeon;Lee, Sung-Hee;Kim, Won-Bae
    • Biomolecules & Therapeutics
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    • v.6 no.3
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    • pp.312-316
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    • 1998
  • Efficacy and in vivo bioassay of recombinant human erythropoietin (rho-EPO), was investigated. Efficacy studies were conducted in normal, and cisplatin-induced anemic rats. Normal and anemic animals were treated intravenously with rhu-EPO for 5 days, and the changes in the number of red blood cells (RBC), hemoglobin concentration (Hb), hematocrit value (Hct) and percentage reticulocyte value (Ret, reticulocyte/RBC) were examined. In normal rats, rho-EPO significantly increased RBC, Hb, Hct and Ret at the doses of 50∼ 1,250 lU/kg/day in a dose-dependent fashion. Cisplatin-induced anemic rats showed significant increase of RBC, Hb, Hct and Ret after administration of rho-EPO (50-200 lU/kg/day) in a dose-dependent manner. These changes of hematological parameters disappeared gradually after cessation of the treatment. The in vivo bioassay results in polycythemic mice showed that rho-EPO had 90% of bioactivity compared to NIBSC standard rhu-EPO. These results suggest that rho-EPO might be useful for the therapy of anemia originated from renal failure and chemotherapy-induced anemia.

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GPR78 promotes lung cancer cell migration and metastasis by activation of Gαq-Rho GTPase pathway

  • Dong, Dan-Dan;Zhou, Hui;Li, Gao
    • BMB Reports
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    • v.49 no.11
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    • pp.623-628
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    • 2016
  • GPR78 is an orphan G-protein coupled receptor (GPCR) that is predominantly expressed in human brain tissues. Currently, the function of GPR78 is unknown. This study revealed that GPR78 was expressed in lung cancer cells and functioned as a novel regulator of lung cancer cell migration and metastasis. We found that knockdown of GPR78 in lung cancer cells suppressed cell migration. Moreover, GPR78 modulated the formation of actin stress fibers in A549 cells, in a RhoA- and Rac1-dependent manner. At the molecular level, GPR78 regulated cell motility through the activation of $G{\alpha}q$-RhoA/Rac1 pathway. We further demonstrated that in vivo, the knockdown of GPR78 inhibited lung cancer cell metastasis. These findings suggest that GPR78 is a novel regulator for lung cancer metastasis and may serve as a potential drug target against metastatic human lung cancer.

An Analysis of the Port Transportation System (항만운송시스템의 분석에 관한 연구)

  • 이철영;문성혁
    • Journal of the Korean Institute of Navigation
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    • v.7 no.1
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    • pp.1-32
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    • 1983
  • The delay due to congestion has recently attracted widespread attention with the analysis of over-all operation at the port. But, the complexity of the situation is evident in view of the large number of factors which impinge on the considerable end. Queueing theory is applicable to a large scale transportation system which is associated with arrivals of vessels in a large port. The attempt of this paper is to make an extensive analysis of the port transport system and its economic implications from the viewpoint that port is one of the physical distribution facilities and a kind of queueing system which includes ships and cargoes as port customer. By analyzing the real data on the Port of Pusan, it is known that this port can be represented as a set of multi-channel with identical setof Poisson arrival and Erlang service time, and also it is confirmed that the following formula is suitable to calculate the mean delay in this port, namely, $W_4={\frac{\rho}{\lambda(1-\rho)} {\frac{e_N(\rho{\cdot}N)}{D_{N-1}(\rho{\cdot}N)}$ where, ${\lambda}$: mean arrival rate $\mu$: mean servicing rate; N: number of servicing channel; ${\rho}$: utillization rate (${\lambda}/N{\mu}$) $e_N$: the Poisson function Coming to grips with the essentials of the cost of delay due to congestion, a simple ship journey cost model is adopted and the operating profit sensitivity to variation in port time is examined, and for purpose of a future development for port princing service the marginal cost is approximately calculated on the basis of queueing theory.

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$^{13}$C NMR Study of the Application of the 'Tool of Increasing Electron Demand' to the 9-Aryl-tricyclo[3.3.1.0$^{2,8}$]non-9-yl, and 8-Aryl-Tetracyclo[3.2.1.0$^{2,7}$.0$^{4,6}$]oct-8-yl cations

  • Wie-Chang Jin;Gweon-Young Ryu;Chun Yoon;Shin Jung Hyu
    • Bulletin of the Korean Chemical Society
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    • v.10 no.6
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    • pp.591-595
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    • 1989
  • The$^{13}C$ NMR shifts of a series of para-substituted 9-aryl-tricyclo$[3.3.1.0^{2,8}]$non-9-yl and 8-aryl-tetracyclo$[3.2.1.0^{2,7}.0^{4,6}]$-oct-8-yl cations were measured in $FSO_3H/SO_2ClF \;at\; -90^{\circ}C\; or\; -70^{\circ}C$ in order to examine whether the ${\rho}^{c+}$ values can be used to explain the mechanism for the stabilization of the geometrically rigid cyclopropylcarbinyl cations. Plots of the ${\Delta}{\delta}^{c+}$ shifts against ${\sigma}^{c+}$ reveal excellent linear correlation. The tricyclononyl systems yield a ${\rho}^{c+}$ value of -4.95 with a correlation coefficient r = 0.9948. The tetracyclo-octanyl systems give a ${\rho}^{c+}$ value of -6.39 with r = 0.9943. A fair parallelism exists between the results of $^{19}F$ nmr studies and the change of ${\rho}^{c+}$ values in these cations. Accordingly, the present study established that the ${\rho}^{c+}$ value can be used as a mearsure of the geometric influence for the charge delocalization in cyclopropylcarbinyl cations.

SECOND-ORDER UNIVEX FUNCTIONS AND GENERALIZED DUALITY MODELS FOR MULTIOBJECTIVE PROGRAMMING PROBLEMS CONTAINING ARBITRARY NORMS

  • Zalmai, G.J.
    • Journal of the Korean Mathematical Society
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    • v.50 no.4
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    • pp.727-753
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    • 2013
  • In this paper, we introduce three new broad classes of second-order generalized convex functions, namely, ($\mathcal{F}$, $b$, ${\phi}$, ${\rho}$, ${\theta}$)-sounivex functions, ($\mathcal{F}$, $b$, ${\phi}$, ${\rho}$, ${\theta}$)-pseudosounivex functions, and ($\mathcal{F}$, $b$, ${\phi}$, ${\rho}$, ${\theta}$)-quasisounivex functions; formulate eight general second-order duality models; and prove appropriate duality theorems under various generalized ($\mathcal{F}$, $b$, ${\phi}$, ${\rho}$, ${\theta}$)-sounivexity assumptions for a multiobjective programming problem containing arbitrary norms.

The Effects on Horizontal Web Reinforcements for Reinforced High Strength Concrete Deep Beams (춤이 깊은 고강도 철근콘크리트 보의 수평전단철근 효과에 관한 연구)

  • 신성우;성열영;안종문;이광수;박무용;김형준
    • Proceedings of the Korea Concrete Institute Conference
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    • 1996.10a
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    • pp.337-344
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    • 1996
  • Reinforced concrete deep beams with conpressive strengths in the range of 500kg/$\textrm{cm}^3$~750kg/$\textrm{cm}^3$ were tested under two-point loding. All the beams were singly reinforced with main steel percent $\rho$=1.29% and with nominal percentage of vertical shear reinflrcements $\rho_v$=0.26%. According to shear-span to depth ratio a/d. The beams were tested for four horizontal shear reinforcement ratio $\rho_h$, ranging from$\rho_h$=0.0 to $\rho_h$=0.53. The results indicate that the horizontal shear reinforcements of beams have an effect on failure load and on ductile behavior of deep beams. The test results are compared with predictions based on the current ACI Building Code. The computated reports in the paper will have designers assured for design of high strength concrete deep beam. Though ACI Code is relatively conservative and tend to non-economical, ACI Code has the merit that is easy to use.

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Frequency Characteristics of Anodic Oxide Films on Tantalum

  • Lee, Dong-Nyung;Yoon, yong-Ku
    • Nuclear Engineering and Technology
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    • v.5 no.1
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    • pp.30-37
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    • 1973
  • The Nishitani's equations for impedance of anodic oxide films have been derived based on a p-i-n model under the assumption of $\omega$$\varepsilon$$\rho$$_{ο}$<<4$\pi$<<$\omega$$\varepsilon$$\rho$$_{\omega}$, where $\omega$ is angular frequency, $\varepsilon$ is dielectric constant, and $\rho$$_{ο}$ and $\rho$$_{\omega}$ are the resistivity of the interface region and the intrisic region of the anodic oxide film, respectively. Since it is not possible to evaluate all parameters in the equations, however, any clear physical picture cannot be obtained from the equations. Therefore, the equations are modified under the assumption of $\omega$$\tau$$_{\omega}$>>1 and In(1+$\omega$$^2$$\tau$$_{ο}$$^2$)<<1, where $\tau$$_{\omega}$=$\varepsilon$$\rho$$_{\omega}$(4$\pi$) and $\tau$$_{ο}$=$\varepsilon$$\rho$$_{ο}$/(4$\pi$). The modified equations are then used to explain the change in the frequency characteristics of anodic oxide films when they are heated. The change in impedance of anodic oxide films when they are heated is attributed mainly to the increase in the diffusion layer and to the decrease in the resistivity of anodic oxide films.s.

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