• Korean Journal of Veterinary Research
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• v.6 no.1
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• pp.53-56
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• 1966

Number of dairy cow patients treated at Hyup Doug Large Animal Clinic during the year July 1,1965, through June 30, 1966, were amounted to 485 cases and the result of analysis of disease incidence during one year period were us follows; 1. In the etiologic diagnostic categories, diseases caused by static mechanical abnormality were most productive and 28.1% of all diagnoses involved in this category. 2. In the topographic diagnostic categories, 39.4% of all diagnoses involved the urogenital system and were obeserved most productive. 3. As a result of each topographic diagnostic categories were subdivided into disease entities, 13.4% of all diagnoses involved the retained placenta and this were observed most productive in the miscellaneous disease enties. Next productive diseases were miscellaneous ovarian disease (10.9%), indigestion (10.3%), mastitis (8.0%) and metritis (6.8%) chronologically.

• Korean Journal of Veterinary Research
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• v.7 no.2
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• pp.56-59
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• 1967

Number of dairy cow patients diagnosed and treated at Hyup Dong Large Animal Clinic during the year, October 1, 1966, through September 30, 1967, were amounted to 1,119 cases and the result of analysis of disease incidence during one year period were as follow: 1. In the etiologic diagnostic categories, diseases cause by infection with lower organism were most productive and 43.3% of all diagnosis involved in this category. 2. In the topographic diagnostic categories, 37.3% of all diagnosis involved the urogenital system and were observed most productive. 3. As a result of each topographic diagnostic categories were subdivided into disease entities, 21.4% of all diagnosis involved the mastitis and this were observed most productive in the miscellaneous disease entities. Next productive disease were indigestion (11.9%), endometritis(11.5%), miscellaneousl ovarian disease(11.1%) and retained placenta(81.1%) chronologicaly.

• Asian-Australasian Journal of Animal Sciences
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• v.16 no.3
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• pp.435-444
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• 2003

In 1957, Schwarz and Foltz discovered that selenium (Se) was an essential trace mineral and nutritionists then started extensive studies to figure out the metabolic function of this element which has been called as toxic mineral. The discovery that glutathione peroxidase (GSH-Px) contained Se demonstrated a biochemical role for Se as an essential trace element. The major physiological function of Se containing GSH-Px is thought to maintain low levels of $H_2O_2$ and other hydroperoxides in the cell to prevent tissues from peroxidation damages. It is known that the GSH-Px activity is increased when animals were fed high dietary levels of Se. Chemical properties of Se have much in common with sulfur (S) therefore Se would follow the sulfur pathways in its metabolism in animal body. Two sources of Se are available for supplementation of Se in animal feed. Inorganic Se can also exist in selenide (-2), elemental (0), selenite (+4) and selenate (+6) oxidation state with other minerals. When sulfur in S containing amino acids is replaced by Se, organic Se can be made and named "eleno"prior to the name of S containing amino acid, i.e. selenomethionine. Selenium deficiency affects humans as well as animals and dysfunctions such as exudative diathesis, retained placenta, mastitis, liver necrosis, Keshan disease, numerous diseases and cancer. From several centuries ago, Se toxicity was recognized in various animal species and much of the current toxic Se levels has been established largely based upon the controlled toxicity studies used inorganic Se. Toxic effects of Se in animal result in reduced feed intake, growth retardation, ataxia, diarrhea, alopecia and sloughing of hooves. However, several experiments demonstrated that Se deficiencies or toxicities were varied by dietary Se levels and sources. Recent studies demonstrated that the incidence of colorectal and prostate cancer was reduced by approximately 50% when humans consumed 200 ${\mu}g$ of Se daily.

• Journal of Veterinary Clinics
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• v.1 no.1
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• pp.11-23
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• 1984

Epizootiolosical factors of 166 cows with abomasal displacement were studied and in 21 out of 166 cows, the functions of liver and kidney were also tested. 1. Incidence of abomasal displacement was perdominant in small sized dairy herd less than 15 cows, using area of paddock below 165㎡. 2. Out of 166 cows with abomasal displacement, 116 cows (70%) were found left sided displacement and 50 cows (30%) were right. 3. Generally, one to two weeks were taken before treatment of veterinarian following onset of sign of the diseases. Therefore many cases were found to be severe in their illness. 4, Incidence rate of abomasal displacement was predominant in summer season (June, July and Au-gust). However, occurence of the disease was continuous throughout the year. About 80 percent of abomasal displacement was distributed from first to third purturition. 5. High milk production and feeding with high concentrates and low roughage showed a tendendy to occurs the disease. 6. Approximately 75% of abomasal displacement was distributed within 1 month pre and post partum. 7. Cows with abomasal displacement consumed little concetrates and 75% of cows with abomasal displacement passed abnormal fecal material. 8. Sixty six out of 166 cows with abomsal displacement were coincident with diseases such as retained placenta, metritis, traumatic reticulo-peritonitis and mastitis. 9. In many cass of abomasal displacement, abomasum was extended with gas. 10. Activities of AST ana LDH showed the trends to reduce after surgical intervention comparing with pre-surgery. Bilirubin concentration markedly decreased after surgical treatment comparing with pre-surgery. 11. The concentration of BUN and creatinine moderatly decreased after surgery compared with pre-surgery.

• Journal of Veterinary Clinics
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• v.10 no.1
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• pp.141-145
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• 1993

The present study was performed in order to clarify the significance of serum amyloid A(SAA) estimation for the diagnosis of bovine amyloidosis and SAA as a useful parameter for the health status in herds. Twelve dutch dairy cows with final diagnosis(2 with amyloidosis, 3 with acute inflammatory disease and 7 with chronic inflammatory disease) were used to charify the significance of SAA determination for the diagnosis of bovine amyloidosis. The SAA concentration in the group of inflammatory disease was higher than that of amyloldotic group. Further the SAA value in the group of acute inflammatory disease was higher than that of chronic ones. To clarify the significance of SAA estimation as a useful parameter for the health status in herds, two Korean dairy farms(A and B) were selected and the SAA concentration was determined in total 76 cows(49 from A farm and 27 from B farm). The SAA concentration in cows from A farm was ranged with 0～169%. The cows with high level of SAA(31～169%) had the disease histories(1 with retained placenta, 3 with chronic mastitis, 2 with acute mastitis, 1 with abortion and acute mastitis, 1 with ovarian dysfunction, 1 with downer cow syndrome and 1 with laceration of the teat). The SAA value in the cows from B farm was ranged with 0～29% and disease history was not detected. In conclusion the SAA determination only is thought to be difficult for the diagnosis of bovine amyloidosis. Furthermore SAA estimation is thought to be a useful parameter for the health status in herds.

• Journal of Veterinary Clinics
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• v.35 no.6
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• pp.251-257
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• 2018

We determined the relationships between calving season and the incidence of postpartum disorders, milk yield, and reproductive performance in dairy cows. Data regarding cow parity, postpartum disorders, milk yield, and reproduction were collected from 1,478 lactations. The incidence of retained placenta was higher in spring- and summer-calving cows than in autumn- and winter-calving cows (P < 0.05). The incidence of septicemic metritis was highest in spring- and summer-calving cows, and was higher in autumn-calving cows than in winter-calving cows (P < 0.05). The incidence of metabolic disorders was higher in summer-calving cows than in autumn- and winter-calving cows (P < 0.01). The mean milk yield 1 and 2 months after calving was higher in spring-calving cows than in summer-calving cows (P < 0.05). The percentage of cows that had resumed cycling, defined by detection of a corpus luteum using ultrasonography 4 weeks after calving, was highest in autumn-calving cows, and was higher in summer- and winter-calving cows than in spring-calving cows (P < 0.05). The hazard of first insemination by 150 days after calving was higher in summer- and autumn-calving cows (hazard ratio [HR] = 1.19; P < 0.05) than in spring-calving cows. The hazard of pregnancy by 210 days after calving was also higher in summer-calving (HR = 1.24; P < 0.05) and autumn-calving (HR = 1.59; P < 0.0001) cows than in spring-calving cows. The probability of conception at the first insemination was higher (P < 0.0001) in autumn-calving (odds ratio [OR] = 1.96) and winter-calving (OR = 2.04) cows than in spring-calving cows. In conclusion, spring calving is associated with the worst, and autumn calving with the best, postpartum health and reproductive performance, whereas milk yield is higher in spring-calving cows than in summer-calving cows. Therefore, an effective strategy to support postpartum health and fertility should be instituted for spring-calving dairy cows kept in the Korean climate.

• Korean Journal of Animal Reproduction
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• v.24 no.1
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• pp.19-33
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• 2000

Eighty dairy farms (38 farms responded) in Palmerston North area of New Zealand were questioned by mail questionnaire on: 1) general characteristics, 2) milk yield and feed supplementary, 3) reproductive efficiencies (12 questions) and 4) reproductive disorders (12 questions) from February to July, 1998. Among those 4 items, the reproductive efficiencies (3) and disorders (4), various diseases and culling rates were surveyed and analyzed for Korean dairy farmers (especially in Cheju island) and compared with New Zealand. The results are as follows: 1. Fifteen farms in 38 dairy farms relied entirely on artificial insemination, the rest of 23 dairy farms (60.5%) raised 5∼6 bulls to increase conception rate. The dairy farmers in Palmerston North used artificial insemination from Oct 4th to Dec 10th for 42.8 days, and then used bulls from that point to coming Jan 10th for 41.4 days. The submission rate within 3, 6 and 10 weeks following the initiation of AI season was 84.7, 93.9 and 97.9% respectively. 2. The average age of heifers at the first estrus, pregnancy and calving was 11.0, 18.0 and 24.7 months respectively, and an average 1.4 estrus cycles were required for conception. The intervals of estrus recurrence and the following conception after calving were 38 and 68 days respectively. 3. Among inseminated cows, calving, abortion and empty cow was 90.9, 1.6 and 7.4% respectively. Calving rate decreased according to increasing farm size, while the number of empty cows decreased. 4. Stillbirth, retained placenta and delivery abnormalities were 5.3, 3.7 and 5.5% respectively, not different depend on herd size. 5. The incidence of milk fever, grass tetany, and ketosis was 3.6, 3.0 and 1.0%, respectively. The delivery abnormality and mastitis treated with medicine were 3.1 and 6.7%, but decreased according to farm size. Lameness was 8.6% on average, but over 10% in farms which has more than 400 milking cows. 6. Among the culled cows (15.5% of the total), those culled due to an old age, lameness and other diseases were 2.9, 1.8 and 4.3% respectively and those culled due to low milk production, reproductive abnormality reduced with farm size. 7. Compared with the data collected in Korea, the reproductive efficiency was better, and lameness, metabolic problem and culling rate were higher in New Zealand

• Journal of Animal Science and Technology
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• v.44 no.5
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• pp.561-572
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• 2002

The objective of this study was to evaluate a feed additives used mainly in lactating cow diets in transient pregrent cow diets. The study was conducted as a completely randomized design with forty Holstein pregnant cows to determine the effect of feeding Aspergillus oryzae(T2), Saccharomyces cerevisiae mixture(T3) and enzyme(cellulase, xylanase) - releasing chemicals(ERC) (T4) on the dry matter intake, milk yield, milk composition and metabolic disorders. Dry matter intake was similar among treatments for 3 weeks prepartum but cows fed enzyme tended to increased feed intake compared to no additives treatment both in calving day and for 3 weeks postpartum. Cows fed Aspergillus oryzae, Saccharomyces cerevisiae and ERC produced more milk than those fed no additives. However, there is no significant difference among treatments. Concentration of glucose was not significantly different among treatment prepartum but that in plasma of cows fed ERC was higher at calving and 3 weeks postpartum compared to others. Increase in NEFA began at 3 weeks prepartum and accelerate during the final 7 days before calving at all treatments but lower for ERC-treated cows at calving and 3 weeks postpartum. Ca concentration not different among treatment prepartum and postpartum. Corticoid content decreased significantly for cows fed ERC compared to those fed non-additives. Metabolic disorder was not occurred in cows fed ERC. However, ketosis and displased abomasum were happened 1 cow when fed non-additives, metritis 1 cow when fed Aspergillus oryzae and retained placenta 1 cow in all treatments except cows fed ERC.

• Journal of Veterinary Clinics
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• v.34 no.4
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• pp.255-260
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• 2017

Ketosis has become a very common and important metabolic disorder that causes substantial economic loss in modern dairy herds. We determined the risk factors for ketosis and associations with some blood metabolite concentrations in dairy cows. Blood from 475 Holstein cows on four dairy farms was collected weekly until 4 weeks after calving to measure blood ${\beta}$-hydroxybutyrate (BHBA) concentrations using electronic handheld meters. Cows were grouped based on the BHBA concentration into two groups: a ketosis group (${\geq}1.2mmol/L$, n = 150) and a non-ketosis group (< 1.2 mmol/L, n = 325). Peripartum health status (dystocia, retained placenta, and metritis), cow parity, and calving season were recorded to identify the risk factors for ketosis. Serum albumin, total cholesterol (TCH), and haptoglobin concentrations were compared between sub-groups of cows selected from the ketosis (n = 92) and non-ketosis (n = 50) groups 1 week postpartum ($7.5{\pm}0.2days$). The farm influenced the incidence of ketosis (P < 0.05). Cows calved during summer tended to have a higher risk (odds ratio [OR]: 1.61, P < 0.1) of ketosis than cows calved during spring. Cows with parities of two (OR: 1.95, P < 0.05) and three or higher (OR: 2.55, P < 0.01) were at higher risk than primiparous cows. Cows with metritis had a higher risk (OR: 7.02, P < 0.0001) of ketosis than cows without metritis. Serum albumin and TCH concentrations were lower (P < 0.01) in the ketosis group than in the non-ketosis group, whereas haptoglobin concentration was higher (P < 0.05) in the ketosis group than in the non-ketosis group. In conclusion, our results indicate that farm, summer calving, parity greater than one, and postpartum disease (metritis) were risk factors for ketosis. In addition, lower serum albumin and TCH concentrations and higher haptoglobin concentration were also associated with the incidence of ketosis in dairy cows.

• Journal of Veterinary Clinics
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• v.33 no.2
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• pp.87-92
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• 2016

This field study investigated the effects of dystocia on the postpartum complications, milk production, and reproductive performance in Holstein dairy cows. Calving difficulty was scored on a rank scale of 1 to 5. Cows with a calving score of three or higher were judged to have dystocia. The cows (n = 565) were categorized based on the presence (n = 61) or absence (n = 504, control) of dystocia. The incidence of retained placenta (45.9% vs. 16.3%), metritis (39.3% vs. 17.1%), endometritis (47.5% vs. 16.3%) and pyometra (9.8% vs. 1.2%) were greater in cows from the dystocia group than those from the control group (p < 0.0001); however, there was no difference in the incidence of metabolic disorders (32.8% vs. 31.0%) between the two groups (p > 0.05). The prevalence of culling was higher in cows from the dystocia group (26.2%) than in those from the control group (14.5%, p < 0.05). During the 5-month postpartum period, milk production was lower (p < 0.05) in cows from the dystocia group than in those from the control group. Furthermore, the hazard of insemination by 150 days in milk (DIM) was lower in cows from the dystocia group (hazard ratio [HR] = 0.64, p < 0.005) than in those from the control group. Logistic regression analysis revealed that the odds ratio for the probability of pregnancy after the first artificial insemination was 0.36 times (p < 0.05) higher in cows from the dystocia group than in those from the control group. The hazard of pregnancy by 360 DIM was lower in cows from the dystocia group (HR = 0.45, p = 0.0001) than in those from the control group. In conclusion, dystocia resulted in increased postpartum complications, and decreased milk production and reproductive performance in Holstein dairy cows, leading to increased culling.