• Title/Summary/Keyword: resistance changes

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Corn Gluten Hydrolysate Affects the Time-Course of Metabolic Changes Through Appetite Control in High-Fat Diet-Induced Obese Rats

  • Lee, Hyojung;Lee, Hyo Jin;Kim, Ji Yeon;Kwon, Oran
    • Molecules and Cells
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    • v.38 no.12
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    • pp.1044-1053
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    • 2015
  • This study first investigated the effects of corn gluten hydrolysate (CGH) (1.5 g/day) administration for 7 days on appetite-responsive genes in lean Sprague-Dawley (SD) rats. In a second set of experiments, the metabolic changes occurring at multiple time points over 8 weeks in response to CGH (35.33% wt/wt) were observed in high-fat (HF, 60% of energy as fat) diet-fed SD rats. In lean rats, the hypothalamus neuropeptide-Y and proopiomelanocortin mRNA levels of the CGH group were significantly changed in response to CGH administration. In the second part of the study, CGH treatment was found to reduce body weight and perirenal and epididymal fat weight. CGH also prevented an increase in food intake at 2 weeks and lowered plasma leptin and insulin levels in comparison with the HF group. This reduction in the plasma and hepatic lipid levels was followed by improved insulin resistance, and the beneficial metabolic effects of CGH were also partly related to increases in plasma adiponectin levels. The Homeostasis Model of Assessment - Insulin Resistance (HOMA-IR), an index of insulin resistance, was markedly improved in the HF-CGH group compared with the HF group at 6 weeks. According to the microarray results, adipose tissue mRNA expression related to G-protein coupled receptor protein signaling pathway and sensory perception was significantly improved after 8 weeks of CGH administration. In conclusion, the present findings suggest that dietary CGH may be effective for improving hyperglycemia, dyslipidemia and insulin resistance in diet-induced obese rats as well as appetite control in lean rats.

Fabrication and Resistance Characteristics of Smart Paint for Temperature Sensor (온도 센서를 위한 스마트 페인트 제작 및 저항 특성)

  • Ahn, Ju-Hun;Lee, Chang-Yull
    • Journal of Aerospace System Engineering
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    • v.13 no.2
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    • pp.43-50
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    • 2019
  • Satellite and aircraft components are greatly affected by the possibility for missions and safety due to temperature effects. In the field of fuel cells, research is actively carried out for UAV. For the efficiency and stability of the fuel cells, the temperature for operations must be confirmed. In this paper, a smart paint was fabricated with $BaTiO_3$ and $SrTiO_3$ ceramics in order to take advantage of the rapid characteristics of the PTC thermistor, which is the resistance changes abruptly above the Curie point. A coating agent was prepared to prevent the paint from peeling off the samples and the coated models were checked for resistance changes. Moreover, the resistance change of the $BaTiO_3$ and $SrTiO_3$ with temperature conditions was measured before and after coating.

The Effect of the Resistance Respiratory Muscle Exercise with Transcutaneous Electrical Nerve Stimulation on Respiratory Muscle Tone and Pulmonary Function of Chronic Stroke Patients (경피신경전기자극과 호흡근 저항운동 동시 적용이 만성 뇌졸중 환자의 호흡근 근긴장도와 폐 기능에 미치는 영향)

  • Cho, Yong-Hun;Cho, Kyun-Hee
    • Journal of the Korean Society of Physical Medicine
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    • v.17 no.1
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    • pp.75-83
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    • 2022
  • PURPOSE: This study was conducted to investigate the effect of the resistance respiratory muscle exercise with transcutaneous electrical nerve stimulation (TENS) on the respiratory muscle tone and pulmonary function of stroke patients. METHODS: Twenty stroke patients were divided into the TENS group (n = 7), placebo TENS group (n = 7), and control group (n = 6), and each intervention was performed on the three groups 5 times a week for 4 weeks. The assessment was carried out by measuring changes in the muscle tone of the latissimus dorsi and abdominal external obliques, and pulmonary function. RESULTS: In this study, the TENS group and the placebo TENS group had significant increases in the paretic side latissimus dorsi muscle tone, forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), and peak expiratory flow (PEF). There was no significant difference in changes in respiratory muscle tone between the three groups. The pulmonary function was significantly different between the three groups, and it was observed from the results of the post-hoc test that FVC showed a significant increase in the TENS group and the placebo TENS group compared to the control group. CONCLUSION: Through this study, it was found that the respiratory muscle resistance exercise was more effective as a method to increase respiratory muscle tone and pulmonary function in stroke patients than combined transcutaneous electrical nerve stimulation.

Resistance Induction by Salicylic Acid Formulation in Cassava Plant against Fusarium solani

  • Saengchan, Chanon;Phansak, Piyaporn;Thumanu, Kanjana;Siriwong, Supatcharee;Le Thanh, Toan;Sangpueak, Rungthip;Thepbandit, Wannaporn;Papathoti, Narendra Kumar;Buensanteai, Natthiya
    • The Plant Pathology Journal
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    • v.38 no.3
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    • pp.212-219
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    • 2022
  • Fusarium root rot caused by the soil-borne fungus Fusarium solani is one of the most important fungal diseases of cassava in Thailand, resulting in high yield losses of more than 80%. This study aimed to investigate if the exogenous application of salicylic acid formulations (Zacha) can induce resistance in cassava against Fusarium root rot and observe the biochemical changes in induced cassava leaf tissues through synchrotron radiation based on Fourier-transform infrared (SR-FTIR) microspectroscopy. We demonstrated that the application of Zacha11 prototype formulations could induce resistance against Fusarium root rot in cassava. The in vitro experimental results showed that Zacha11 prototype formulations inhibited the growth of F. solani at approximately 34.83%. Furthermore, a significant reduction in the disease severity of Fusarium root rot disease at 60 days after challenge inoculation was observed in cassava plants treated with Zacha11 at a concentration of 500 ppm (9.0%). Population densities of F. solani were determined at 7 days after inoculation. Treatment of the Zacha11 at a concentration of 500 ppm resulted in reduced populations compared with the distilled water control and differences among treatment means at each assay date. Moreover, the SR-FTIR spectral changes of Zacha11-treated epidermal tissues of leaves had higher integral areas of lipids, lignins, and pectins (1,770-1,700/cm), amide I (1,700-1,600/cm), amide II (1,600-1,500/cm), hemicellulose, lignin (1,300-1,200/cm), and cellulose (1,155/cm). Therefore, alteration in defensive carbohydrates, lipids, and proteins contributed to generate barriers against Fusarium invasion in cassava roots, leading to lower the root rot disease severity.

Cellular and regional specific changes in multidrug efflux transporter expression during recovery of vasogenic edema in the rat hippocampus and piriform cortex

  • Kim, Yeon-Jo;Kim, Ji-Eun;Choi, Hui-Chul;Song, Hong-Ki;Kang, Tae-Cheon
    • BMB Reports
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    • v.48 no.6
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    • pp.348-353
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    • 2015
  • In the present study, we investigated the characteristics of drug efflux transporter expressions following status epilepticus (SE). In the hippocampus and piriform cortex (PC), vasogenic edema peaked 3-4 days after SE. The expression of breast cancer resistance protein (BCRP), multidrug resistance protein-4 (MRP4), and p-glycoprotein (p-GP) were decreased 4 days after SE when vasogenic edema was peaked, but subsequently increased 4 weeks after SE. Multidrug resistance protein-1 (MRP1) expression gradually decreased in endothelial cells until 4 weeks after SE. These findings indicate that SE-induced vasogenic edema formation transiently reduced drug efflux pump expressions in endothelial cells. Subsequently, during recovery of vasogenic edema drug efflux pump expressions were differentially upregulated in astrocytes, neuropils, and endothelial cells. Therefore, we suggest that vasogenic edema formation may be a risk factor in pharmacoresistent epilepsy. [BMB Reports 2015; 48(6): 348-353]

Investigation of the Hydrogen Storage Mechanism of Expanded Graphite by Measuring Electrical Resistance Changes

  • Im, Ji-Sun;Jang, Seung-Soon;Lee, Young-Seak
    • Bulletin of the Korean Chemical Society
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    • v.33 no.9
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    • pp.3033-3038
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    • 2012
  • The hydrogen storage mechanism of graphite was studied by measuring the electrical resistance change. Graphite was expanded and activated to allow for an easy hydrogen molecule approach and to enlarge the adsorption sites. A vanadium catalyst was simultaneously introduced on the graphite during the activation process. The hydrogen storage increased due to the effects of expansion, activation, and the catalyst. In addition, the electrical resistance of the prepared samples was measured during hydrogen molecule adsorption to investigate the hydrogen adsorption mechanism. It was found that the electrical resistance changed as a result of the easy hydrogen molecule approach, as well as of the adsorption process and the catalyst. It was also notable that the catalyst improved not only the hydrogen storage capacity but also the speed of hydrogen storage based on the response time. The hydrogen storage mechanism is suggested based on the effects of expansion, activation, and the catalyst.

Electroless Ni-P Plating and Heat Treatments of the Coating Layer for Enhancement of the Cavitation Erosion Resistance of Vessel Propellers (선박 프로펠러의 케비테이션 침식 저항 향상을 위한 Ni-P 무전해 도금층 형성 및 열처리를 통한 미세조직 제어)

  • Kim, Young-jae;Son, In-Jun;Yi, Seonghoon
    • Korean Journal of Materials Research
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    • v.27 no.8
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    • pp.409-415
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    • 2017
  • For enhanced cavitation erosion resistance of vessel propellers, an electroless Ni-P plating method was introduced to form a coating layer with high hardness on the surface of Cu alloy (CAC703C) used as vessel propeller material. An electroless Ni-P plating reaction generated by Fe atoms in the Cu alloy occurred, forming a uniform amorphous layer with P content of ~10 wt%. The amorphous layer transformed to (Ni3P+Ni) two phase structure after heat treatment. Cavitation erosion tests following the ASTM G-32 standard were carried out to relate the microstructural changes by heat treatment and the cavitation erosion resistance in distilled water and 3.5 wt% NaCl solutions. It was possible to obtain excellent cavitation erosion resistance through careful microstructural control of the coating layer, demonstrating that this electroless Ni-P plating process is a viable coating process for the enhancement of the cavitation erosion resistance of vessel propellers.

Effects of Laser Surface Melting on the Pitting Resistance of Alloy 690 (Alloy 690의 공식저항성에 미치는 레이저 표면 용융의 영향)

  • Kim, Young-Kyu;Jhee, Tae-Gu
    • Journal of the Korean Society for Heat Treatment
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    • v.14 no.3
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    • pp.145-150
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    • 2001
  • The effect of laser welding and surface treatment, developed as a method of repairing steam generator tubes, on the pitting corrosion resistance of alloy 690 was examined. The surfaces of some heat-treated Alloy 690 materials were melt-treated using the Nd-YAG laser beam, and then examined to characterize the microstructures. The resistance to pitting corrosion was evaluated by measuring of Ep(pitting potential) through the electrochemical tests and also by measuring the degree of pit generation through the immersion tests. The pit formation characteristics were investigated by observing microstructural changes and pit morphologies. The results show that the resistance to pitting corrosion increases in the order of the following list; solution annealed Alloy 690, thermally treated Alloy 690, and laser surface melt-treated Alloy 690. The melted region was found to have a cellular structure and fine precipitates. It was confirmed that the resistance of Alloy 690 to pit initiation and also to pit propagation was higher when it was laser treated than treated otherwise.

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Evaluation of Sequential Planting Method for Screening of Durable Resistance against Rice Blast in Rice Breeding Program

  • Goh, Jaeduk;Kim, Byoung-Ryun;Shin, Dong Bum;Kang, In Jeong;Lee, Bong Choon;Kang, Hang-Won;Han, Seong-Sook
    • Research in Plant Disease
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    • v.21 no.1
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    • pp.20-23
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    • 2015
  • A sequential planting method was developed to screen rice plants with durable resistance against rice blast in a short time, and applied for several years in Korean rice breeding program. In this study, we showed the advantages of a sequential planting method compared to other pathogenicity tests. The correlation analysis among three pathogenicity tests and other factors demonstrated that durable resistance depended on the average of diseased leaf area and the number of compatible pathogens. Significant correlations were found in the nursery test but not in the field test result. In addition, we traced changes in the pathogen population during sequential planting stages through re-isolation of the pathogen. The portion of compatible pathogens was increased during sequential planting. Through this study, we provide an effective sequential planting method and direction of durable resistance in a breeding program.

Electrical Characteristics of Carbon Nanotubes by Plasma and Microwave Surface Treatments

  • Cho, Sang-Jin;Shrestha, Shankar Prasad;Lee, Soon-Bo;Boo, Jin-Hyo
    • Bulletin of the Korean Chemical Society
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    • v.35 no.3
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    • pp.905-907
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    • 2014
  • The plasma and microwave surface treatments of carbon nanotubes that loaded on plastic substrates were carried out with expecting a change of carbon nanotube dispersion by increasing treatment time. The microwave treatment process was undergone by commercial microwave oven (800 W). The electrical property was measured by hall measurement and resistance was increased by increasing $O_2$ flow rate of plasma, suggesting an improvement of carbon nanotube dispersion and a possibility of controlling the resistances of carbon nanotubes by plasma surface treatment. The resistance was increased in both polyethylene terephthalate and polyimide substrates by increasing $O_2$ flow rate. Resistance changes only slightly with different $O_2$ flow treatment in measure rho for all polyimide samples. Sheet resistance is lowest in polyimide substrate not due to high carbon nanotube loading but due to tendency to remain in elongated structure. $O_2$ or $N_2$ plasma treatments on both polyethylene terephthalate and polyimide substrates lead to increase in sheet resistance.