Cellular and regional specific changes in multidrug efflux transporter expression during recovery of vasogenic edema in the rat hippocampus and piriform cortex |
Kim, Yeon-Jo
(Department of Anatomy and Neurobiology, College of Medicine, Hallym University)
Kim, Ji-Eun (Department of Anatomy and Neurobiology, College of Medicine, Hallym University) Choi, Hui-Chul (Institute of Epilepsy Research, College of Medicine, Hallym University) Song, Hong-Ki (Institute of Epilepsy Research, College of Medicine, Hallym University) Kang, Tae-Cheon (Department of Anatomy and Neurobiology, College of Medicine, Hallym University) |
1 | Rigau V, Morin M, Rousset MC et al (2007) Angiogenesis is associated with blood-brain barrier permeability in temporal lobe epilepsy. Brain 130, 1942-1956 DOI ScienceOn |
2 | Kim JE, Choi HC, Song HK et al (2010) Levetiracetam inhibits interleukin-1 beta inflammatory responses in the hippocampus and piriform cortex of epileptic rats. Neurosci Lett 471, 94-99 DOI ScienceOn |
3 | Kim JE and Kang TC (2011) The P2X7 receptor-pannexin-1 complex decreases muscarinic acetylcholine receptormediated seizure susceptibility in mice. J Clin Invest 121, 2037-2047 DOI ScienceOn |
4 | Kim JE, Ryu HJ, Yeo SI and Kang TC (2010) P2X7 receptor regulates leukocyte infiltrations in rat frontoparietal cortex following status epilepticus. J Neuroinflammation 7, 65 DOI ScienceOn |
5 | Löscher W and Potschka H (2002) Role of multidrug transporters in pharmacoresistance to antiepileptic drugs. J Pharmacol Exp Ther 301, 7-14 DOI ScienceOn |
6 | Kim JE, Yeo SI, Ryu HJ et al (2010) Astroglial loss and edema formation in the rat piriform cortex and hippocampus following pilocarpine-induced status epilepticus. J Comp Neurol 518, 4612-4628 DOI ScienceOn |
7 | Kim JE, Ryu HJ, Choi SY and Kang TC (2012) Tumor necrosis factor--mediated threonine 435 phosphorylation of p65 nuclear factor-B subunit in endothelial cells induces vasogenic edema and neutrophil infiltration in the rat piriform cortex following status epilepticus. J Neuroinflammation 9, 6 DOI ScienceOn |
8 | Jo SM, Ryu HJ, Kim JE et al (2011) Up-regulation of endothelial endothelin-1 expression prior to vasogenic edema formation in the rat piriform cortex following status epilepticus. Neurosci Lett 501, 25-30 DOI ScienceOn |
9 | Sheen SH, Kim JE, Ryu HJ, Yang Y, Choi KC and Kang TC (2011) Decrease in dystrophin expression prior to disruption of brain-blood barrier within the rat piriform cortex following status epilepticus. Brain Res 1369, 173-183 DOI ScienceOn |
10 | Kim DS, Kim JE, Kwak SE et al (2008) Spatiotemporal characteristics of astroglial death in the rat hippocampoentorhinal complex following pilocarpine-induced status epilepticus. J Comp Neurol 511, 581-598 DOI ScienceOn |
11 | Kim JE, Ryu HJ, Yeo SI and Kang TC (2011) P2X7 receptor differentially modulates astroglial apoptosis and clasmatodendrosis in the rat brain following status epilepticus. Hippocampus 21, 1318-1333 DOI ScienceOn |
12 | Deeley RG and Cole SP (1997) Function, evolution and structure of multidrug resistance protein (MRP). Semin Cancer Biol 8, 193-204 DOI ScienceOn |
13 | Jedlitschky G, Burchell B and Keppler D (2000) The multidrug resistance protein 5 functions as an ATP-dependent export pump for cyclic nucleotides. J Biol Chem 275, 30069-30074 DOI ScienceOn |
14 | Bankstahl JP and Löscher W (2008) Resistance to anti- epileptic drugs and expression of P-glycoprotein in two rat models of status epilepticus. Epilepsy Res 82, 70-85 DOI ScienceOn |
15 | Sisodiya SM, Lin WR, Harding BN, Squier MV and Thom M (2002) Drug resistance in epilepsy: expression of drug resistance proteins in common causes of refractory epilepsy. Brain 125, 22-31 DOI ScienceOn |
16 | Rizzi M, Caccia S, Guiso G et al (2002) Limbic seizures induce P-glycoprotein in rodent brain: functional implications for pharmacoresistance. J Neurosci 22, 5833-5839 |
17 | Zhang L, Ong WY and Lee T (1999) Induction of P-glycoprotein expression in astrocytes following intracerebroventricular kainate injections. Exp Brain Res 126, 509-516 DOI |
18 | Kuteykin-Teplyakov K, Brandt C, Hoffmann K and Löscher W (2009) Complex time-dependent alterations in the brain expression of different drug efflux transporter genes after status epilepticus. Epilepsia 50, 887-897 DOI ScienceOn |
19 | Cornford EM and Oldendorf WH (1986) Epilepsy and the blood-brain barrier. Adv Neurol 44, 787-812 |
20 | Mayhan WG (2001) Regulation of blood-brain barrier permeability. Microcirculation 8, 89-104 |
21 | Aronica E, Gorter JA, Jansen GH et al (2003) Expression and cellular distribution of multidrug transporter proteins in two major causes of medically intractable epilepsy: focal cortical dysplasia and glioneuronal tumors. Neuroscience 118, 417-429 DOI ScienceOn |
22 | Goralski KB, Hartmann G, Piquette-Miller M and Renton KW (2003) Downregulation of mdr1a expression in the brain and liver during CNS inflammation alters the in vivo disposition of digoxin. Br J Pharmacol 139, 35-48 DOI ScienceOn |
23 | Begley DJ (2004) ABC transporters and the blood-brain barrier. Curr Pharm Des 10, 1295-1312 DOI ScienceOn |
24 | Lee G, Dallas S, Hong M and Bendayan R (2001) Drug transporters in the central nervous system: brain barriers and brain parenchyma considerations. Pharmacol Rev 53, 569-596 DOI ScienceOn |
25 | Clinckers R, Smolders I, Meurs A, Ebinger G and Michotte Y (2005) Quantitative in vivo microdialysis study on the influence of multidrug transporters on the blood-brain barrier passage of oxcarbazepine: concomitant use of hippocampal monoamines as pharmacodynamic markers for the anticonvulsant activity. J Pharmacol Exp Ther 314, 725-731 DOI ScienceOn |
26 | Brandt C, Bethmann K, Gastens AM and Löscher W (2006) The multidrug transporter hypothesis of drug resistance in epilepsy: Proof-of-principle in a rat model of temporal lobe epilepsy. Neurobiol Dis 24, 202-211 DOI ScienceOn |
27 | van Vliet EA, van Schaik R, Edelbroek PM et al (2006) Inhibition of the multidrug transporter P-glycoprotein improves seizure control in phenytoin-treated chronic epileptic rats. Epilepsia 47, 672-680 DOI ScienceOn |
28 | Shen J, Carcaboso AM, Hubbard KE et al (2009) Compartment-specific roles of ATP-binding cassette transporters define differential topotecan distribution in brain parenchyma and cerebrospinal fluid. Cancer Res 69, 5885-5892 DOI ScienceOn |
29 | Rappa G, Finch RA, Sartorelli AC and Lorico A (1999) New insights into the biology and pharmacology of the multidrug resistance protein (MRP) from gene knockout models. Biochem Pharmacol 58, 557-562 DOI ScienceOn |
30 | Sørensen AT and Kokaia M (2013) Novel approaches to epilepsy treatment. Epilepsia 54, 1-10 DOI ScienceOn |
31 | Löscher W and Potschka H (2005) Blood-brain barrier active efflux transporters: ATP-binding cassette gene family. NeuroRx 2, 86-98 DOI ScienceOn |
32 | Schinkel AH, Wagenaar E, Mol CA and van Deemter L (1996) P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs. J Clin Invest 97, 2517-2524 DOI ScienceOn |
![]() |