• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.4
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• pp.559-565
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• 2010

Cancer is already a well-recognized main cause of mortality and the incidence of cancer is increasing steadily. Because conventional treatment modalities for cancer accompanies severe side effects, traditional medicine has been considered as alternatives to reduce the adverse effects and its use has continued to rise in cancer therapy. This study aims to summarize and make a reference of radioprotective effects of herbs worldwide. In this process, this review surveyed all papers of radioprotective-focused studies using herbal medicine in PubMed database and finally 44 papers were included. The type of materials, formation of experiments, type of herbal medicine, their action and mechanisms, and type of cancer were analyzed. The number of studies on radioprotective effects of herbal medicine has increased since 2000. The main formation of experiments was clinical study and the portion was 45% and the proportion of the research using prescriptions was 51% and the research using herbal products was 25%. Herbs and prescriptions having the effects of tonifying and nourishment were used the most. Most of herbal medicine in this study can enhance immune function, increase anti-oxidant effect, regulate cell cycle and increase sensitivity to radiotherapy. This study will provide the useful information on development of herbal medicine having radioprotective effects.

• The Journal of Internal Korean Medicine
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• v.40 no.6
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• pp.1152-1168
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• 2019

Objectives: The aim of this study was to present several proposals for future pulse diagnosis practice and research by investigating the trend of pulse diagnosis studies in Korea. Methods: We searched online medical databases, including National Discovery for Science Leaders (NDSL), the Oriental Medicine Advanced Searching Integrated System (OASIS), the Research Information Sharing Service (RISS), and the Korean Traditional Knowledge Portal (KTKP), for pulse diagnosis articles in Korea. We selected articles on pulse diagnosis but excluded duplicate articles, articles irrelevant to pulse diagnosis, and articles published in foreign countries. Results: In the first screening, 801 articles were selected. We found 251 articles and classified them according to category. The medical engineering field had 148 articles. A total of 24 articles were related to algorithms for pulse wave detection, 34 to sensors, five to pressurization technology, 16 to systems, 11 to remote medical service, five to mobiles, nine to trends, and 44 to basic research. The Korean medicine field had 103 articles. A total of 41 articles were devoted to literature reviews, 20 to case reports, 11 to constitutional medicine, six to experimental studies, and 25 to relevant research. Conclusion: More efforts to practice pulse diagnosis for various diseases should be made and the results actively published.

• Journal of Society of Preventive Korean Medicine
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• v.22 no.1
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• pp.15-28
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• 2018

Objectives : The purpose of this study was to analyze the trend of clinical research on quantitative indicators of Mibyeong in traditional chinese medicine(TCM). Method : The journal search was performed using china national knowledge infrastructure(CNKI) database. Our inclusion criteria were as following: TCM clinical researches for quantitative indicators of Mibyeong. Exclusion criteria were as following: non-TCM clinical researches, used intervention methods. Results : Eleven clinical researches were analyzed in this study. Four of these researches classify the Mibyeong as a type of pattern identification(PI) and studied the characteristics of the PI quantitative indicators. Mibyeong diagnosis was done through guidelines and questionnaires, each was used at a similar rate. Quantitative indicators mentioned in the selected researches were blood indices, nailfold capillary, complexion, color of tongue substance and coating, pulse wave diagrams and heart rate variability. Among them, seven researches related to blood indices were the most. Blood indicators include whole-blood viscosity, plasma viscosity, fibrinogen, packed cell volume(Hct), triglycerides, total cholesterol, HDL-C, LDL-C, glucose, BUN/CREA, luteinzing hormone, estradiol, follicle stimulating hormone, IgA, IgG, etc. Conclusions : Based on this results, in combination with western medicine, it seems necessary to try to interpret the Mibyeong in more various ways. Even if the same Mibyeong, it is necessary to identify the index which changes according to the PI or chief complaint, and to set the Mibyeong standard corresponding thereto.

• Journal of Korean Medicine Rehabilitation
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• v.33 no.4
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• pp.45-59
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• 2023

Objectives The aim of this study was to analyze the trends of researches on oriental medicine treatments for supraspinatus tendinopathy. Methods We used five databases for searching researches; Korean studies Information Service System, Oriental Medicine Advanced Searching Integrated System, Research Information Sharing Service, PubMed, and China National Knowledge Infrastructure. Only randomized controlled trials suitable for the subject were selected. The methodological quality of included randomized controlled trials (RCTs) was assessed by the Cochrane risk of bias tool. Results Twenty randomized controlled trials were analyzed. There were 9 types of treatment interventions; acupuncture, acupotomy, pharmacopuncture, electroacupuncture, fire needling, warming needle, catgut-embedding therapy, herbal medicine, cupping. The most frequently used treatment intervention was acupuncture and acupotomy. There were 9 outcome measurements including visual analog scale (VAS), Constant-Murley Score (CMS), and range of motion. The most used measurement was VAS. As a result of meta-analysis, acupuncture was more effective than control group in VAS. Additionally, acupotomy was clinically significant compared to control groups in VAS and CMS. Conclusions In this review, we analyzed researches on effectiveness of oriental medicine for supraspinatus tendinopathy. A provisional conclusion can be produced that acupuncture and acupotomy showed beneficial effect to supraspinatus tendinopathy. Although there were some RCT studies, many of them had a high risk of bias, so it is hard to conclude that our study can include overall clinical status. Further well-designed trials are needed.

• Journal of Oriental Neuropsychiatry
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• v.20 no.4
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• pp.79-89
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• 2009

Objectives : To address suitable method for designing clinical trial intervening Traditional Korean Herbal Medicine on General anxiety disorder through the recent clinical research in Chinese Herbal Medicine. Methods : Randomized, controlled trials(RCTs) of treatment of general anxiety disorder intervening herbal medicine were searched through CNKI databases. We examined several item of studies and evaluated using Jadad scale. We searched articles in CNKI with the key word "General anxiety disorder or 廣範性焦慮症", among them we selected the clinical trial studies related with herbal medicine except for case reports, studies of acupuncture therapy or west medicines. Results : 11 RCT studies of herbal medicine met inclusion criteria. The Studies used CCMD-3, HAMA as inclusion tool and mainly HAMA as a evaluation tool. Studies were progressed for 2-8 weeks, mostly used various positive control. Experiment medicine were mainly 理氣劑, 安神劑. In most studies, experiment group made similar or higher efficacy in comparison with control group. Mean Jadad score of studies was $1.3{\pm}0.67$, and only one study was double-blinded among 11 studies. Conclusions : RCT studies on general anxiety disorder of chinese herbal medicine tend to focus on investigating effect of herbal medicine through setting positive control group with CCMD-3 and HAMA. But, most studies had low quality of trial, for lack of pattern identification, evaluation and inclusion tool of chinese medicine. Clinical trials of general anxiety disorder should provide good quality by randomization, double-blinding, and multi-site trial.

• The Journal of Pediatrics of Korean Medicine
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• v.31 no.1
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• pp.25-42
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• 2017

Objectives The goal of this review was to investigate clinical, experimental and literature studies of Korean medicine on atopic dermatitis (AD) of Korean children in Korean medicine literature, seeking for the better research methods for more effective treatments. Methods Electronic investigations were practiced on AKOP (The Association of Korean Oriental Pediatrics, http://www.akop.or.kr) to collect theses which were published by J Pediatr Korean Med. The key word 'Atopy' was used for searching to ensure that every related thesis was collected. The publication date was limited from 1996 to 2016. The selected literatures were assessed mainly according to distributions of study type, publication year, scale, treatment and its efficacy. Results 55 papers were selected from 59 studies. In these collected 55 related theses, there were 29 experimental studies (52.73%), 18 clinical studies (32.73%), 8 review studies (14.55%). In the 29 experimental studies, there were 20 studies (68.97%) using NC/Nga mouse as subjects. The mite antigen was used to trigger AD by 8 studies (27.59%). The studies have been utilizing DNCB and DNFB instead of mite antigen since 2011. All the experimental studies showed that the Korean medicine was effective in AD. In total 18 clinical studies, 3 studies (16.67%) were case reports, only 1 thesis (5.56%) was conducted by case control study and the rest were case series studies. 7 studies (38.89%) of 18 studies diagnosed AD according to Hanifin and Rajka's diagnostic criteria (1980), only 1 study (5.56%) according to the Korean standard and the rest 10 studies (55.56%) didn't mention diagnostic criteria. 12 clinical studies (66.67%) showed efficacy in treating AD. There were 10 studies (55.56%) only employing internal treatments and 1 thesis (5.56%) didn't mention the exact prescription. Naesowhajungtang-kamibang, Saenghyeoryunbue-um were used 3 times (16.67%) as the internal medicine respectively. 5 theses (27.78%) were combined with acupuncture therapy. Hegu (LI4), Sanyinjiao (SP6) were used in 4 theses, and Taichong (LR3), Quchi (LI11), Zusanli (ST36) in 3 theses. The number of acupoints chosen from The Spleen meridian of Foot-Taiyin was the largest. There were 8 review theses. 2 were about the foreign oriental medicine, 3 were about the external medicine or external treatment methods, and 3 other studies were about severity scoring systems, the methodological study in the latest clinical study, overview for pattern and results of herbal medicine-derived AD clinical researches. Conclusions The experimental studies and clinical studies showed the effectiveness of Korean medicine treatments. However, this study still needs improving by conducting more comparative studies and using better research methods, in order to find more effective treatments to improve clinical efficacy.

• Journal of Korean Medicine Rehabilitation
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• v.33 no.3
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• pp.97-113
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• 2023

Objectives This study examined the trends in domestic and international research on the treatment of sarcopenia and analyzed the effectiveness of the treatment. Based on the results, we suggest directions for future Korean medicine research on sarcopenia. Methods The study was conducted using Arksey and O'Malley's scoping review methodology. It included three international databases (PubMed, EMBASE, Cochrane Library) and five domestic databases (Korean studies Information Service System, Korean Medical database, Oriental Medicine Advanced Search Integrated System, Research Information Sharing Service, ScienceON) were used. Literatures published until April 30, 2023, including the contents of 'sarcopenia' and Korean Medicine treatment', were searched. Results A total of 45 studies were included in the analysis. The number of studies on Korean medicine treatments for sarcopenia is steadily increasing, with the majority of studies coming from Asian countries. Of the 45 studies, 30 were conducted in the field of medicine, and the study design was analyzed into 10 clinical studies and 35 non-clinical studies. Among the 10 clinical studies, the most common treatment interventions were herbs (n=4), followed by Daoist exercises (n=3). The most common diagnostic criteria used in clinical studies were those published by the Asian working group for sarcopenia, and various physical examinations and laboratory tests were used as outcome measures. Conclusions The future direction of Korean medicine research on sarcopenia should be to expand the number of clinical studies applying Korean medicine treatment interventions.

• The Journal of Korean Obstetrics and Gynecology
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• v.22 no.1
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• pp.243-262
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• 2009

Purpose: In recent, there have been a lot of studies exploring effective methods to relieve pains and sufferings of women delivered of child. The ultimate purpose of the study is to investigate the developmental trends of the complementary alternative medicine(CAM, hereafter), which has increasingly obtained the approval of the women and therefore established the academic foundations in effect. Methods: Systematic analysis with diverse written materials concerning the complementary alternative medicine was carried out. For the analysis, materials related with the issue of the study were searched at the Pubmed, the Korea Education & Research Information Service. Results: 1. One of the results of interest is the verification of the fact in that diverse complementary therapies are nowadays substantially applied to the many situations of delivery and childbirth. 2. The results showed clearly that CAM has several prominent influences on the whole process of the delivery: from the reduce of the pains and the time for delivery, to increasement of the satisfactional level of the mother. 3. According to the results, the emphasis of CAM is mainly placed not just on the relieving of pains and sufferings of the mothers, but on empowering them to face them with self-confidence. 4. The results of the study suggest strongly that the professionals should provide mothers with useful information and methods to help them to get through the pains during the delivery period. Conclusion: The result of the study is to suggest persuasively that more systematic attention should be paid to the researches exploring effectiveness and stability and safety of CAM.

• Journal of Acupuncture Research
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• v.20 no.1
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• pp.191-201
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• 2003

Objective : To research the trends of study related to tension-type headache and migrain with acupuncture in PubMed, and to establish the hereafter direction of acupuncture. for tension-type headache and migrain. Methods : We searched in PubMed, with tension-type headache, migrain and acupuncture limitted by abstract and enterz data 10 years. Results : 1. The pattern of the study was as follows: Review article(18), Clinical Trials(23), meta analysis(2) and rondomized controlled trials(16). We further estimated 23 articles. 2. Many of these studies provide equivocal results because of designs, sample size and the others, but in the majority of the trials were concludes that acupuncture offers benefits in the treatment of headache. 3. Acupuncture methods need individualization, a carefully selected placebo and cross-over design must have adequate time between the two treatment periods.

• Journal of Acupuncture Research
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• v.19 no.6
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• pp.171-183
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• 2002

Objective : To research the trends of study related to myofascial pain syndrome(MPS) and acupuncture in PubMed, and to establish the hereafter direction of myofascial pain syndrome(MPS) with acupuncture. Methods : We searched in PubMed, with myofascial pain syndrome and acupuncture, trigger point and acupuncture limitted by abstract. Results : 1. The pattern of the study was as follows : Review article(11), Clinical(11) rondomized controlled trials(21). We further estimated 24 articles. 2. Many of these studies provide equivocal results because of designs, sample size and the other, affirmative view is 10 articles, contradictive view is 6 articles, and somewhat reservative regards are 8 articles for therapeutic effect of myofascial pain syndrome with acupuncture. 3. Suggestions on further endolphin related research, neurophysiology, biophysics and phamacology are made. 4. More clinical data would be needed to prove effects of myofascial pain syndrome with acupuncture.