• Genomics & Informatics
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• v.2 no.4
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• pp.163-166
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• 2004

• Journal of the Earthquake Engineering Society of Korea
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• v.25 no.3
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• pp.129-135
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• 2021

After the manual shutdown of the Wolseong nuclear power plant due to an earthquake in Gyeongju in 2016, anxiety about the earthquake safety of nuclear power plants has become a major social issue. The shear wall structure used as a major structural element in nuclear power plants is widely used as a major structural member because of its high resistance to horizontal loads such as earthquakes. However, due to the complexity of the structure, it is challenging to predict the dynamic characteristics of the structure. In this study, a three-story shear wall structure is fabricated, and the in-structure response characteristics of the shear wall structure are evaluated through shaking table tests. The test is performed using the Gyeongju earthquake that occurred in 2016, and the response characteristics due to the domestic earthquake are evaluated.

• The Journal of Asian Finance, Economics and Business
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• v.8 no.7
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• pp.423-431
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• 2021

This research (1) examines the effect of stock ownership structure on capital structure; (2) explains the effect of stock ownership structure on corporate value; and (3) investigates the influence of capital structure on corporate value. This research is categorized as a quantitative research, which is directed to test various theories. In this study, the population of all consumption companies listed on the Indonesia Stock Exchange (IDX) consist of 38 companies. Population data in this study are all consumption companies, which have gone public in the period from 2010 to 2015. In this study, given the objectives and problem formulation and hypothesis, the analysis method used is Generalized Structural Component Analysis (GSCA). Ownership structure has a significant effect on capital structure; ownership structure has no significant effect on corporate value; capital structure has a significant effect on corporate value; corporate value has a significant effect on capital structure. Previous research found different results. Some researchers found a positive relationship and other researchers found a negative relationship, and there are studies that found both significant and non-significant effects. The inconsistency of previous research results prompted the researchers to examine the effect of ownership structure on capital structure and corporate value.

• Molecules and Cells
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• v.43 no.11
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• pp.935-944
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• 2020

Aryl hydrocarbon receptor nuclear translocator (ARNT) plays an essential role in maintaining cellular homeostasis in response to environmental stress. Under conditions of hypoxia or xenobiotic exposure, ARNT regulates the subset of genes involved in adaptive responses, by forming heterodimers with hypoxia-inducible transcription factors (HIF1α and HIF2α) or aryl hydrocarbon receptor (AhR). Here, we have shown that ARNT interacts with DDB1 and CUL4-associated factor 15 (DCAF15), and the aryl sulfonamides, indisulam and E7820, induce its proteasomal degradation through Cullin-RING finger ligase 4 containing DCAF15 (CRL4^DCAF15) E3 ligase. Moreover, the two known neo-substrates of aryl sulfonamide, RNA-binding motif protein 39 (RBM39) and RNA-binding motif protein 23 (RBM23), are not required for ARNT degradation. In line with this finding, aryl sulfonamides inhibited the transcriptional activities of HIFs and AhR associated with ARNT. Our results collectively support novel regulatory roles of aryl sulfonamides in both hypoxic and xenobiotic responses.

• Bulletin of the Korean Chemical Society
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• v.25 no.8
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• pp.1241-1243
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• 2004

• Bulletin of the Korean Chemical Society
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• v.25 no.12
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• pp.1937-1940
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• 2004

• Journal of the Korean Society for information Management
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• v.28 no.1
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• pp.145-170
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• 2011

The purpose of this paper is to suggest a pilot model of knowledge organizing system which reflects the knowledge structure of research papers, using a case analysis on the "Korean Research Memory" of the National Research Foundation of Korea. In this paper, knowledge structure of the research papers in humanities and social science is described and the function of the "Korean Research Memory" for scholarly sense-making is analysed. In order to suggest the pilot model of the knowledge organizing system, the study also analysed the relation between indexed keyword and knowledge structure of research papers in the Korean Research Memory. As a result, this paper suggests 24 axioms and 11 inference rules for an ontology based on semantic relation of the knowledge structure.

• Steel and Composite Structures
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• v.16 no.3
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• pp.289-303
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• 2014

In recent, development of construction and design technology gives taller, larger and heavier steel framed structures. With the tendency of increasing high-rise building, this study is strongly related to structural system, one of significant components in structural design. This study presents an innovative structural system, with high performance steel material, diagrid. Its detail, structural analysis, and structural experiments are all included for the development of new structures.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.25 no.6
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• pp.357-364
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• 2013

In previous study, the hybrid floating structure composed of a pontoon and a semi-submersible was suggested to reduce the motions of floating structure. It was reported that the suggested hybrid floating structure could reduce the motions. However, the hybrid floating structure could not support enough buoyancy. In this study, the combination floating structure is newly suggested to resolve the problem. In order to adopt the shape of floating structures reducing the motions, the hydrodynamic analysis of various floating structures such as the pontoon, the hybrid and the combination of floating structure is carried out through hydrodynamic analysis program ANSYS AQWA. It is found that the combination floating structure is remarkably effective to reduce the motions compared to the other cases. Thus, the suggested combination floating structure may be a useful offshore structure for constructing a very large floating structure.

• Molecules and Cells
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• v.42 no.10
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• pp.729-738
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• 2019

Autophagy is an important process for protein recycling. Oligomerization of p62/SQSTM1 is an essential step in this process and is achieved in two steps. Phox and Bem1p (PB1) domains can oligomerize through both basic and acidic surfaces in each molecule. The ZZ-type zinc finger (ZZ) domain binds to target proteins and promotes higher-oligomerization of p62. This mechanism is an important step in routing target proteins to the autophagosome. Here, we determined the crystal structure of the PB1 homo-dimer and modeled the p62 PB1 oligomers. These oligomer models were represented by a cylindrical helix and were compared with the previously determined electron microscopic map of a PB1 oligomer. To accurately compare, we mathematically calculated the lead length and radius of the helical oligomers. Our PB1 oligomer model fits the electron microscopy map and is both bendable and stretchable as a flexible helical filament.