• Title/Summary/Keyword: research program

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Expression Profiling of Lipopolysaccharide Target Genes in RAW264.7 Cells by Oligonucleotide Microarray Analyses

  • Huang, Hao;Park, Cheol-Kyu;Ryu, Ji-Yoon;Chang, Eun-Ju;Lee, Young-Kyun;Kang, Sam-Sik;Kim, Hong-Hee
    • Archives of Pharmacal Research
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    • v.29 no.10
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    • pp.890-897
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    • 2006
  • In inflammatory responses, induction of cytokines and other immune regulator genes in macrophages by pathogen-associated signal such as lipopolysaccharide (LPS) plays a crucial role. In this study, the gene expression profile changes by LPS treatment in the macrophage/monocyte lineage cell line RAW264.7 was investigated. A 60-mer oligonucleotide microarray of which probes target 32381 mouse genes was used. A reverse transcription-in vitro translation labeling protocol and a chemileuminescence detection system were employed. The mRNA expression levels in RAW264.7 cells treated for 6 h with LPS and the control vehicle were compared. 747 genes were up-regulated and 523 genes were down-regulated by more than 2 folds. 320 genes showing more than 4-fold change by LPS treatment were further classified for the biological process, molecular function, and signaling pathway. The biological process categories that showed high number of increased genes include the immunity and defense, the nucleic acid metabolism, the protein metabolism and modification, and the signal transduction process. The chemokine-cytokine signaling, interleukin signaling, Toll receptor signaling, and apoptosis signaling pathways involved high number of genes differentially expressed in response to LPS. These expression profile data provide more comprehensive information on LPS-target genes in RAW264.7 cells, which will be useful in comparing gene expression changes induced by extracts and compounds from anti-inflammatory medicinal herbs.

Practical Algorithms on Lunar Reference Frame Transformations for Korea Pathfinder Lunar Orbiter Flight Operation

  • Song, Young-Joo;Lee, Donghun;Kim, Young-Rok;Bae, Jonghee;Park, Jae-ik;Hong, SeungBum;Kim, Dae-Kwan;Lee, Sang-Ryool
    • Journal of Astronomy and Space Sciences
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    • v.38 no.3
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    • pp.185-192
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    • 2021
  • This technical paper deals the practical transformation algorithms between several lunar reference frames which will be used for Korea pathfinder lunar orbiter (KPLO) flight operation. Despite of various lunar reference frame definitions already exist, use of a common transformation algorithm while establishing lunar reference frame is very important for all members related to KPLO mission. This is because use of slight different parameters during frame transformation may result significant misleading while reprocessing data based on KPLO flight dynamics. Therefore, details of practical transformation algorithms for the KPLO mission specific lunar reference frames is presented with step by step implementation procedures. Examples of transformation results are also presented to support KPLO flight dynamics data user community which is expected to give practical guidelines while post processing the data as their needs. With this technical paper, common understandings of reference frames that will be used throughout not only the KPLO flight operation but also science data reprocessing can be established. It is expected to eliminate, or at least minimize, unnecessary confusion among all of the KPLO mission members including: Korea Aerospace Research Institute (KARI), National Aeronautics and Space Administration (NASA) as well as other organizations participating in KPLO payload development and operation, or further lunar science community world-wide who are interested in KPLO science data post processing.

Prevalence and antimicrobial resistance of Salmonella spp. isolated from duck farms in Jeollanam-do Province, South Korea

  • Sin-Wook Park;Keon Kim;Chang-Yun Je;Chang-Hyeon Choi;Sang-Gyue Choi;Jong-Soo Lim;Ok-Mi Jeong;Guk-Hyun Suh;Chang-Min Lee
    • Korean Journal of Veterinary Service
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    • v.46 no.3
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    • pp.211-218
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    • 2023
  • This study was carried out to investigate the prevalence and antimicrobial resistance of Salmonella serotypes in duck farms of Jeollanam-do Province, South Korea. A total of 1112 samples (breeder ducks, 286; broiler ducks, 826) were collected from 196 duck farms (breeder duck farms, 25; broiler duck farms, 171) between January 2018 and November 2019. The total prevalence of Salmonella serotypes was 45.4% (89/196) in the duck farms, with no significant difference between prevalence in breeder and broiler duck farms (48% and 45%, respectively; P>0.05). The most prevalent serotype among the 127 Salmonella isolates was Salmonella Typhimurium (20.5%) followed by Salmonella Albany (17.3%), Salmonella Hadar (15.7%), and Salmonella Enteritidis (11.8%). Maximum resistance was observed against penicillin (78.74%), followed by tetracycline (68.50%), and kanamycin (65.35%). Of the 127 isolates, 117 (92.13%) were resistant to ≥3 antimicrobials and 2 to all 18 antimicrobials. Our results demonstrate the presence of Salmonella strains and their resistance to multiple antimicrobials, thus indicating a public health concern in South Korea. The emergence of Salmonella stains that are resistant to multiple drugs highlight the need for careful use of antimicrobials in duck farms.

Variability of Ocean Status around Ulleung Basin and Dok-do by using ARGO Data (무인 해양관측기 (ARGO 플로트) 자료를 이용한 울릉분지 및 독도 주변해역 해황 변동성 분석)

  • Youn, Yong-Hoon;Chang, You-Soon;Hyun, Yu-Kyung;Cho, Chang-Woo;Ku, Ja-Ok;Cho, Min-Kwang;Ban, Young-Seok;Park, Seong-Jun;Kim, Su-Jeong
    • Atmosphere
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    • v.16 no.4
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    • pp.379-385
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    • 2006
  • Meteorological Research Institute (METRI) participates the R&E (Research and Education) program of Korea Science and Engineering Foundation,"Variability of ocean status around Ulleung basin and Dok-do by using ARGO data" as a part of "Carricula development for gifted students" program. From this program, we support students to have an opportunity for handling scientific data with advanced technology and inspire their scientific interests. In this article, we introduce the training processes of this program and the results of data analysis by the students themselves.

Trends of Research and College Education Program in Fashion Marketing: An Analysis of JKSC & IJCF, 2006-2015 (패션마케팅 분야의 연구경향 및 대학 교과과정 특성 분석 - 최근 10년간의 변화와 『복식』지의 연구경향을 중심으로 -)

  • Ji, Hye Kyung;Lee, Soo Jin
    • Journal of the Korean Society of Costume
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    • v.67 no.1
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    • pp.74-94
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    • 2017
  • The purpose of this research was to assess the trends in research and curriculum of college education program in fashion marketing, and to suggest the implications for the research and education of fashion marketing business. The data extracted from the articles published in JKSC/IJCF and the college education curricula from 2006 to 2015 were examined to compare the result with the trend for the last 30 years of JKSC/IJCF research trend and education curricular based on the previous research. The results indicated that more than 70% of research was focused on consumer- oriented subject, such as consumer decision making process and consumer behavior, while more than 70% of education program was directed on firm-oriented subject, such as merchandising and marketing management. These results implied a slight shift for the academic research from consumer to firm oriented when comparing the result with the last 30 years of data, although the education was reclined conversely. The academic research and education program should be related in order to provide fashion industries with well educated human resources.

Development of Analysis Program for Maintenances of Levee Facilities (하천제방 시설물의 유지관리를 위한 분석프로그램 개발)

  • Yoo, Byung-Sun;Park, Yong-Dae;Kim, Hual-Soo;Chang, Ki-Tae
    • Proceedings of the Korean Geotechical Society Conference
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    • 2008.03a
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    • pp.704-715
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    • 2008
  • The Aim of this development is the management of a forecasting analysis program based on a real-time remote sensing data. Using this program it is possible to predict a failure of levee facilities in advance. therefor, it is necessary for making plans of a safety countermove. In this development we have researched the analysis method which could operate effectively the levee facilities using real-time monitoring data from a remote sensing system and the safety managerial program using the algorism from the analysis method developed.

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The Development and Effects of the Program for the Improvement of Preservice Teachers' Critical Thinking Ability (예비교사의 비판적 사고력 향상을 위한 프로그램 개발 및 효과검증)

  • Gang, Seung-Hee;Kim, Dae-Hyun
    • Journal of Fisheries and Marine Sciences Education
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    • v.18 no.2
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    • pp.108-121
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    • 2006
  • The purpose of this study is to develop and to test the program for the improvement of preservice teachers' critical thinking ability. The main research problems to achieve the purpose of research are as follows; first, is the program for the improvement of preservice teachers' critical thinking ability effective to improve the critical thinking skills of preservice teachers? Second, is the program for the improvement of preservice teachers' critical thinking ability effective to improve the critical thinking dispositions of preservice teachers? To evaluate the effect of the program, 30(15; experimental group: 15; control group) sophomores were selected in Pusan. The conclusions of this research are as follows; first, there is a significant difference between experimental group and control group for critical thinking skills test. Second, there is no significant difference between experimental group and control group for critical thinking dispositions test.

Analysis of Operational Status and Effectiveness of Single-Track Accredited Program in ABEEK (공학교육인증의 단일인증프로그램 운영실태 및 효과분석)

  • Han, Jiyoung
    • Journal of Engineering Education Research
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    • v.23 no.4
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    • pp.66-75
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    • 2020
  • This study was conducted using the literature review and survey research to analyze the operational status and effectiveness of the single-track accredited program, which has been mandatory since 2016. The research targets to achieve the purpose of the study were the nationwide engineering education accreditation system operating colleges, departments, and engineering education innovation centers. Finally, 183 copies were collected from faculty members at 69 colleges and 554 copies at the department level. As a result of the survey, the college recognized more positively about the operation of the single-track accredited program, and more than 50% of respondents said that there were difficulties due to the operation of the system. The contents required were analyzed and presented. Based on this, the engineering education accreditation system, including the single-track accredited program, suggested the direction of support at the government level and the ABEEK level to better settle down in the field of engineering colleges.

A Study on the Design of Implemental Strategy and Present States of Critical Technology-21 Research Program (중점개발연구개발사업의 추진전략의 설계 및 현화에 관한 연구)

  • 이상엽;류영수
    • Proceedings of the Technology Innovation Conference
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    • 2000.06a
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    • pp.243-263
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    • 2000
  • Several strategic system are prepared and designed for the critical technology-21, which is a kind of national R&D program and is based on the $\ulcorner$Special Act for Innovation of Science and Technology$\lrcorner$from early of 1998. Various valuables in social-technological, political-technological and econo- technological points and a new R&D planning method, "scenario method, " are considered and tried for overcoming the socio-economical difficulties of country and strategies of this program which is become a implementation skeleton of critical technology-21 are summarized as a implemental model of national R&D program. And present states, sub-projects of same research program are analyzed by type of research group and valuables.

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Basic Research about Natural Dyeing Experience Program Conditions and Participants' Characteristics (천연염색 체험학습의 현황과 체험자의 특성에 관한 기초연구)

  • Kim, Jie-Yurn
    • Fashion & Textile Research Journal
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    • v.11 no.2
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    • pp.350-358
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    • 2009
  • This research has a purpose to examine the actual conditions of natural dyeing program as a personal learning experience, participants' characteristics and common people's interest on natural dyeing nowadays. To examine the actual conditions of natural dyeing center and programs, many web sites and newspapers dealing with natural dyeing were used as main resources. As common people's interest on natural dyeing increased, there were a lot of natural dyeing centers in around country. To examine the interest on natural dyeing and the participants' characteristics of natural dyeing program, the data was obtained from a convenient survey of 326 respondents over 15 years old during 15th, May~30th, July in 2006. Almost 40% of respondents were interested in natural dyeing, but only 19% of respondents had ever participated in natural dyeing experience program. The participants' characteristics such as motivation, participating time, dyeing sources and materials, etc. were examined. Almost 65% of respondents were satisfied with natural dyeing experience. As long as people have interest on natural dyeing, Industrialization of natural dyeing will be advanced.