• Journal of Radiation Protection and Research
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• v.36 no.3
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• pp.119-126
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• 2011

Mitochondrial DNA (mtDNA) deletion is a well-known marker for oxidative stress and aging, and contributes to harmful effects in cultured cells and animal tissues. mtDNA biogenesis genes (NRF-1, TFAM) are essential for the maintenance of mtDNA, as well as the transcription and replication of mitochondrial genomes. Considering that oxidative stress is known to affect mitochondrial biogenesis, we hypothesized that ionizing radiation (IR)-induced reactive oxygen species (ROS) causes mtDNA deletion by modulating the mitochondrial biogenesis, thereby leading to cellular senescence. Therefore, we examined the effects of IR on ROS levels, cellular senescence, mitochondrial biogenesis, and mtDNA deletion in IMR-90 human lung fibroblast cells. Young IMR-90 cells at population doubling (PD) 39 were irradiated at 4 or 8 Gy. Old cells at PD55, and H2O2-treated young cells at PD 39, were compared as a positive control. The IR increased the intracellular ROS level, senescence-associated ${\beta}$-galactosidase (SA-${\beta}$-gal) activity, and mtDNA common deletion (4977 bp), and it decreased the mRNA expression of NRF-1 and TFAM in IMR-90 cells. Similar results were also observed in old cells (PD 55) and $H_2O_2$-treated young cells. To confirm that a increase in ROS level is essential for mtDNA deletion and changes of mitochondrial biogenesis in irradiated cells, the effects of N-acetylcysteine (NAC) were examined. In irradiated and $H_2O_2$-treated cells, 5 mM NAC significantly attenuated the increases of ROS, mtDNA deletion, and SA-${\beta}$-gal activity, and recovered from decreased expressions of NRF-1 and TFAM mRNA. These results suggest that ROS is a key cause of IR-induced mtDNA deletion, and the suppression of the mitochondrial biogenesis gene may mediate this process.

• Journal of Dental Rehabilitation and Applied Science
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• v.39 no.3
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• pp.158-167
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• 2023

As digital technology has advanced in the field of dentistry, the use of computer-aided design/computer-aided manufacturing (CAD/CAM) has brought changes to the stages of dental treatment. The use of CAD/CAM technology in dental restoration offers clinical efficiency and convenience by reducing production time and appointment intervals, while also simplifying the fabrication process to reduce errors. In this case, digital replication and printing of temporary teeth were used to aid a patient with complex medical histories and physical disabilities. The final impression obtained with silicone impression material included information on the vertical dimension, centric relation, and the angle and length of the anterior teeth, which shortened the production time and appointment intervals and increased patient satisfaction. The final restoration was fabricated using milling and monolithic disc techniques, demonstrating appropriate stability, retention, and support, resulting in functional and aesthetic satisfaction.

• Cartoon and Animation Studies
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• s.41
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• pp.279-306
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• 2015

This paper is a study of the changing nature of software for virtual Cyborg self and the virtual body that occur in the game from a philosophical point of view. Looking broadly, the cyborg concept refers to the combination of man and machine. Specifically, there is a hardware cyborg organism to combine human and restoration of machine In addition, there is software cyborg by electronic the human brain of converting a virtual body. Virtual games are cases software-Cyborg applied. In the game , There seems to have characteristics of virtual body and ego that different from general cyborg meaning. To analyze the features, I applied the concept of software-cyborg of Hans morabek and the multiple selves in cyberspace properties of Kim Sun-Hee. generally, software cyborg cloning the brain type tended to invalidate the body due to the nature of the virtual world. But If you look at third-person's view and the game character that made from real actors, it is pursuing the realism of photographic images and it stressed the need for a virtual body in order to maintain the psychological identity of the player. And, The game player crosses the eight characters to choose while completing the mission. This is a big role in the reality ego leads to the desired final ending with the selection and experience to be experienced as self-replication to multiple. These cyber multi-ego looks for an active and positive features compared to the multi-ego in the real world and highlights the advantages of the software cyborg. Game The characteristics of the final result varies depending on the selection of the player. The life and death of a friend is determined by the relationship between the characters friendship. In this case, the virtual self is empirically through trial and error, moral, and try to select the desired setting the standard for intuitive and self own choice. Also It can be fused to the knowledge of multiple selves as one step is formed by a high spiritual introspection. This process is a positive interpretation of the world and their own forms of mental reflection through self-overcoming human, Nietzsche is said that the process is Wibeomenswi.

• Journal of the Korea Organic Resources Recycling Association
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• v.9 no.4
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• pp.81-88
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• 2001

This experiment was carried out to evaluate the effect of residual food compost application on plant growth and physicochemical properties of soil when residual food compost made from the composting process as part of organic waste recycling was applied in soil as variable rate. The treatments were composed non-fertilizer treatment, control treatment applied with pig compost $20Mg(D.W.)ha^{-1}$, and residual food compost treatments each of applied with 20, 40, 60, $80Mg(D.W.)ha^{-1}$ and were randomized complete block design with three replication. Soil pH after experiment was more increased as more increase application of residual food compost. Other chemical properties of soil including EC were also showed the similar results. The plant growth in treatments applied much of residual food compost at the early growth stage was very damaged and these results were proved at the first growth measurement. Production of the red pepper especially reduced in treatments taken growth demage at the early stage and that of $20Mgha^{-1}$ treatment almost same as control treatment. Bulk density was reduced but porosity was increased according to increase of residual food compost application. Considering the reduction of red pepper production and the demage of growth at the early stage by plenty of salt and water soluble application volume of residual food compost was not permitted over of $30Mgha^{-1}$. Additively, to settle the application volume of residual food compost and to evaluate the plant growth and changes of physicochemical properties of soil, the results taken from continual applying is concluded more important than single application.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.37 no.4
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• pp.80-89
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• 2000

In this paper, we propose a new CPLD technology mapping algorithm for sequential circuit under time constraints. The algorithm detects feedbacks of sequential circuit, separate each feedback variables into immediate input variable, and represent combinational part into DAG. Also, among the nodes of the DAG, the nodes that the number of outdegree is more than or equal to 2 is not separated, but replicated from the DAG, and reconstructed to fanout-free-tree. To use this construction method is for reason that area is less consumed than the TEMPLA algorithm to implement circuits, and process time is improved rather than TMCPLD within given time constraint. Using time constraint and delay of device the number of partitionable multi-level is defined, the number of OR terms that the initial costs of each nodes is set to and total costs that the$^1$costs is set to after merging nodes is calculated, and the nodes that the number of OR terms of CLBs that construct CPLD is excessed is partitioned and is reconstructed as subgraphs. The nodes in the partitioned subgraphs is merged through collapsing, and the collapsed equations is performed by bin packing so that it fit to the number of OR terms in the CLBs of a given device. In the results of experiments to MCNC circuits for logic synthesis benchmark, we can shows that proposed technology mapping algorithm reduces the number of CLBs by 15.58% rather than the TEMPLA, and reduces process time rather than the TMCPLD.

• Journal of Korean Society of Forest Science
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• v.3 no.1
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• pp.18-22
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• 1963

1. Objects The experiments of catalytic aharcoaling were carried out for the fallowing purposes. (1) To determine the economically desirable amount of catalytic materials to be used when a catalytic charcoaling is practiced. (2) To observe the rate of carbonization of non-treated charcoal wood when the catalytic charcoaling is proceeded in the same charcoal pit. 2. Meterials (1) Small sample chips made of oak (Q. accutissima Carr.), measured by 0.5cm in width and thickness, respectively, and 1cm in length, were used as charcoal wood in each experiment. (2) Ammonium chloride was used as a catalytic material and electric kiln as a charcoaling apparatus. 3. Experiment (1) The sample chips were put into a electric oven for three hours at the temperature $60^{\circ}{\sim}70^{\circ}C$ in order to reduce some water contents. (2) Oven dried sample chips were then soaked for an hour in solution of ammonium chloride. Three kinds of solution were prepared, that is, 2.5%, 5%, and 10%, solution in which the amount of ammonium chloride used was weighed at the rate of 0.5%, 1.0%, and 2.0% to the total weight of the sample chips, resppectivelly. (3) Soaked sample chips were put in the air for 12 hours to reduce some water contents, and then were put into electric oven for 2 hours at the temperature $105^{\circ}{\sim}110^{\circ}C$. (4) Dried sample chips were kept in a desiccator with control sample chips which were treated excarly the same process as the treated sample chips except only not using the ammonium chloride in the process of soking. (5) Sample chips kept in the desiccator were used at random in each charcoaling experiment. (6) Charcoaling in the electric kiln were carried out by using small crucibles with complete cover to reduce the amount of ash. At each charcoaling experiment four crucibles filled with sample ships, weighed about 20gr, were put into electric kiln. The charcoaling was continued for an hour at the temperature $400^{\circ}{\sim}450^{\circ}C$. (7) In order to investigate the influence given by the gases produced during the catalytic charcoaling to the rate of carbonization of non-treated sample chips, the following experiment was done. (a) A crueible was divided into two parts by inserting a fine iron net at the middle of the crucible, and then non-treated sample chips, weighed about 10gr, were put in the upper part of the crucible and treated sample chips, weighed also about 10gr, were put in the under part. (b) The crucibles filled with two kinds of sample chips were put into a electric kiln for an hour at the temperature $400^{\circ}{\sim}450^{\circ}C$. 4. Results. Results for two replications (with four crucibles in one replication) for each experiment designed are as follows : (1) The rats of carbonization of the non treated sample chips, and that of the treated sample chips with ammonium chloride at the rate of 1.5%, 1.0%, and 2.0% to the total weight of the sample chips used were averaged at 19.85%, 22.63%, 24.14%, and 26.60%, respectively. (2) The rats of carbonization of the non-treated sample chips were averaged at (a) 20.04% (0.5% treatment), (b) 20.28% (1.0% treatment), and (c) 20.61% (2.0% treatment) when the treated sample chips were carbonized in the same crucible.

• The Transactions of the Korea Information Processing Society
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• v.7 no.1
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• pp.224-234
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• 2000

In this paper, we propose a new CPLD technology mapping algorithm for sequential circuit under time constraints. The algorithm detects feedbacks of sequential circuit, separate each feedback variables into immediate input variable, and represent combinational part into DAG. Also, among the nodes of the DAG, the nodes that the number of outdegree is more than or equal to 2 is not separated, but replicated from the DAG, and reconstructed to fanout-free-tree. To use this construction method is for reason that area is less consumed than the TEMPLA algorithm to implement circuits, and process time is improved rather than TMCPLD within given time constraint. Using time constraint and delay of device the number of partitionable multi-level is defined, the number of OR terms that the initial costs of each nodes is set to and total costs that the costs is set to after merging nodes is calculated, and the nodes that the number of OR terms of CLBs that construct CPLD is excessed is partitioned and is reconstructed as subgraphs. The nodes in the partitioned subgraphs is merged through collapsing, and the collapsed equations is performed by bin packing so that if fit to the number of OR terms in the CLBs of a given device. In the results of experiments to MCNC circuits for logic synthesis benchmark, we can shows that proposed technology mapping algorithm reduces the number of CLBs bu 15.58% rather than the TEMPLA, and reduces process time rather than the TMCPLD.

• 모자간호학회지
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• v.4 no.1
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• pp.3-11
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• 1994

Presently there is an increasing demand for home health care services due to changes in the demographic structure as a result of an increasing elderly population, socio-economic improvements, and changes in the family structure, as well as the growing number of people with degenerative diseases. In addition to these reasons, rising medical costs and there a shortage of patient beds space in the hospital, particularly since introduction of national medical insurance. There has been an increasing demand for health care health care services. This study was done to identify the basic data for home health care management. It focused on developing client selection criteria, assessment tools, and recording methods. This was accomplished by the researchers visiting the patients in their homes. The research process included preparation investigation, tool development, training of the project researcher, and visiting the clients in their homes. The research tools are as follows : 1. Record development : a) The selection criteria tool for home health care of postpartum women was a structured tool and consisted of four parts. b) The structured assessment tool consisted of a general items, obstetric history, past medical history, methods of feeding, medications taken before admission, laboratory test results, discharge instructions, discharge medications, family tree, economic status, environmental status, a map, health assessment of postpartum women and their newborns. c) The visit note I consisted of the frequency of visits. Visit note II consisted of the date ; nursing problems ; nursing process including the initial assessment ; nursing goal ; visit plan ; postpartum women and their neonate health status, diagnosis, goal, implementation, evaluation, summary, next plan, for visit revision. d) Problem note consisted of the date, problem numbers, nursing diagnosis, problem appearance date problem resolution date. The research results are as follows : 1. Nursing problems : The nursing problems of the postpartum women and their neonates were evaluated by the number of nursing diagnoses and the change in the pattern of nursing diagnosis related to the number of visits. a) Nursing diagnosis The nursing diagnosis was classified according to physical function, psychosocial function, family system maintained function. b) The changes of nursing diagnosis related to the number of visits. As the type of nursing diagnosis changed related to the number of visits the number of nursing diagnoses decreased. 2. Contents of home health care : The content was categorized according to assessment, direct care, counseling, education, family care, reporting to with the attending doctor. The recommendations based on the research results are as follows : 1. Tool development Replication of this study is needed to test the validity of the assessment tools used. 2. Home visit a) Home health care nurses should be licensed and qualified. A referral form from the attending doctor is needed for legal protection of nurses. b) The first home visit need to be within 24 hours of discharge from the hospital to decrease the anxiety of frightened postpartum women. c) When the changes occur in the newborn's status, home health care nurses should consult a pediatrician. Communication within the home healthcare team is essential and needs to consistent and done smoothly. 3. Home health care A Study is required to develop protocols for education of staff and for operation of all aspects of this program.

• Korean Journal of Acupuncture
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• v.27 no.3
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• pp.1-23
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• 2010

Objectives and methods : The Standards for Reporting Interventions in Clinical Trials of Acupuncture (STRICTA) were published in five journals in 2001 and 2002. These guidelines, in the form of a checklist and explanations for use by authors and journal editors, were designed to improve reporting of acupuncture trials, particularly the interventions, thereby facilitating their interpretation and replication. Subsequent reviews of the application and impact of STRICTA have highlighted the value of STRICTA as well as scope for improvements and revision. To manage the revision process a collaboration between the STRICTA Group, the CONSORT Group, and the Chinese Cochrane Centre was developed in 2008. An expert panel with 47 participants was convened that provided electronic feedback on a revised draft of the checklist. At a subsequent face-to-face meeting in Freiburg, a group of 21 participants further revised the STRICTA checklist and planned dissemination. Results : The new STRICTA checklist, which is an official extension of CONSORT, includes six items and 17 sub-items. These set out reporting guidelines for the acupuncture rationale, the details of needling, the treatment regimen, other components of treatment, the practitioner background, and the control or comparator interventions. In addition, and as part of this revision process, the explanations for each item have been elaborated, and examples of good reporting for each item are provided. In addition, the word "controlled" in STRICTA is replaced by "clinical", to indicate that STRICTA is applicable to a broad range of clinical evaluation designs, including uncontrolled outcome studies and case reports. Conclusions : It is intended that the revised STRICTA, in conjunction with both the main CONSORT Statement and extension for nonpharmacologic treatment, will raise the quality of reporting of clinical trials of acupuncture.

• Journal of the Korean Institute of Traditional Landscape Architecture
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• v.35 no.2
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• pp.26-44
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• 2017

Regarded as Korea's traditional pond, Gungnamj Pond was surmised to be "Gungnamji" due to its geological positioning in the south of Hwajisan (花枝山) and relics of the Gwanbuk-ri (官北里) suspected of being components to the historical records of Muwang (武王)'s pond of The Chronicles of the Three States [三國史記] and Sabi Palace, respectively, yet was subjected to a restoration following a designation to national historic site. This study is focused on the distortion of authenticity identified in the course of the "Gungnamji Pond" restoration and the invention of tradition, whose summarized conclusions are as follows. 1. Once called Maraebangjuk (마래방죽), or Macheonji (馬川池) Pond, Gungnamji Pond was existent in the form of a low-level swamp of vast area encompassing 30,000 pyeong during the Japanese colonial period. Hong, Sa-jun, who played a leading role in the restoration of "Gungnamji Pond," said that even during the 1940s, the remains of the island and stone facilities suspected of being the relics of Gungnamji Pond of the Baekje period were found, and that the traces of forming a royal palace and garden were discovered on top of them. Hong, Sa-jun also expressed an opinion of establishing a parallel between "Gungnamji Pond" and "Maraebangjuk" in connection with a 'tale of Seodong [薯童說話]' in the aftermath of the detached palace of Hwajisan, which ultimately operated as a theoretical ground for the restoration of Gungnamj Pond. Assessing through Hong, Sa-jun's sketch, the form and scale of Maraebangjuk were visible, of which the form was in close proximity to that photographed during the Japanese colonial period. 2. The minimized restoration of Gungnamji Pond faced deterrence for the land redevelopment project implemented in the 1960s, and the remainder of the land size is an attestment. The fundamental problem manifest in the restoration of Gungnamji Pond numerously attempted from 1964 through 1967 was the failure of basing the restorative work in the archaeological facts yet in the perspective of the latest generations, ultimately yielding a replication of Hyangwonji Pond of Gyeongbok Palace. More specifically, the methodologies employed in setting an island and a pavilion within a pond, or bridging an island with a land evidenced as to how Gungnamji Pond was modeled after Hyangwonji Pond of Gyeongbok Palace. Furthermore, Chihyanggyo (醉香橋) Bridge referenced in the designing of the bridge was hardly conceived as a form indigenous to the Joseon Dynasty, whose motivation and idea of the misguided restoration design at the time all the more devaluated Gungnamji Pond. Such an utterly pure replication of the design widely known as an ingredient for the traditional landscape was purposive towards the aesthetic symbolism and preference retained by Gyeongbok Palace, which was intended to entitle Gungnamji Pond to a physical status of the value in par with that of Gyeongbok Palace. 3. For its detachment to the authenticity as a historical site since its origin, Gungnamji Pond represented distortions of the landscape beauty and tradition even through the restorative process. The restorative process for such a historical monument, devoid of constructive use and certain of distortion, maintains extreme intimacy with the nationalistic cultural policy promoted by the Park, Jeong-hee regime through the 1960s and 1970s. In the context of the "manipulated discussions of tradition," the Park's cultural policy transformed the citizens' recollection into an idealized form of the past, further magnifying it at best. Consequently, many of the historical sites emerged as fancy and grand as they possibly could beyond their status quo across the nation, and "Gungnamji Pond" was a victim to this monopolistic government-led cultural policy incrementally sweeping away with new buildings and structures instituted regardless of their original space, and hence, their value.