• Korean Journal of Adult Nursing
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• v.20 no.3
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• pp.386-394
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• 2008

Purpose: The purpose of this study was to examine the effect of topical lidocaine cream on pain and anxiety during the AV fistula puncture among hemodialysis patients. Methods: The study employed one group repeated measurement design. The data were collected from 50 hemodialysis patients who received AV fistula puncture. The topical lidocaine cream was applied 30 minutes before the puncture. The data were measured total 3 times (T1=without lidocaine, T2=2% lidocaine, T3=5% lidocaine). Pain was measured by VAS and a behavioral checklist. Anxiety was measured by Korean manual of SCL-90-R. Results: Patients with 5% lidocaine cream reported significantly lower of VAS pain score than those with 2% lidocaine and without lidocaine. Patients with 2% lidocaine cream reported significantly lower of behavioral pain scores than those without lidocaine, but less effective than 5% lidocaine cream. Patients with 2% lidocaine cream reported significantly lower of anxiety scores than those without lidocaine, but less effective than 5% lidocaine cream. Conclusion: Topical application of lidocaine cream for 30 minutes before AV fistula puncture significantly decreased pain and anxiety among hemodialysis patients. Specifically 5% lidocaine was more effective than 2% lidocaine for both pain and anxiety.

• Research in Community and Public Health Nursing
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• v.28 no.3
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• pp.227-239
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• 2017

Purpose: The purpose of this study was to investigate the effects of peer mentoring program on physical activity, knee joint function, self-care agency and social support, which are health conservation elements in elderly women with osteoarthritis. Methods: This study used a quasi-experimental research design. It is a pretest-and-post 1, post 2 test design of a non-equivalent control group. The subjects were elderly women aged over 65 who were diagnosed with osteoarthritis. A total of 60 patients (experimental group 30, control group 30) who registered with the Senior Welfare Center in City G and in Region D participated in this study. The data were collected from June 29th to September 4th, 2015. The collected data were analyzed with $x^2$ test, Fisher's exact test, independent t-test and repeated measurement ANOVA. Results: The experimental group showed a greater increase in physical activity, knee joint function, self-care agency and social support than the control group. Conclusion: The results indicated that the peer mentoring program is effective in increasing physical activity, knee joint function, self-care agency and social support of elderly women with osteoarthritis.

• The Korean Journal of Applied Statistics
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• v.10 no.1
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• pp.189-201
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• 1997

The primary purpose of this study is to develop a measure of tracking by using a modified kappa statistic. Understanding tracking phenomena in epidemiologic studies is quite important, because precautionary measure can be made in the early stage of the outcome event. Several authors proposed measures of tracking. Among them we compared ours against McMahan's using a simulation study. Finally we applied our procedure and McMahan's to real data. We may conclude that our statistic is adequate in explaining and detecting the tracking phenomenon.

• Journal of Home Health Care Nursing
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• v.26 no.3
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• pp.309-318
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• 2019

Purpose: The study aimed to examine the effects of aroma hand massage on state sanxiety, depression, quality of sleep, and blood pressure levels of palliative patients in hospice. Methods: This study was conducted using a nonequivalent control group with a pretest-posttest design. The participants were 48 palliative patients in hospice (experimental group: 24, control group: 24). The aroma hand massage was given to the experimental group once a day for 5 days. Data were collected between December 2017 to February 2018. Data were analyzed using SPSS 20.0 program with the chi-square test, Fisher's exact test, independent t-test, and repeated measurement analysis of variance(ANOVA). Results: There were significant differences in state anxiety levels (t=2.41, p=.020) and quality of sleep (F=14.29, p<.001). However, significant differences in the levels of depression (t=1.59, p=.119), systolic blood pressure (F=0.37, p=.695), and diastolic blood pressure (F=0.37, p=.695) were observed. The aroma hand massage was effective in improving the quality of sleep and state anxiety levels of palliative patients in a hospice. Conclusion: The aroma hand massage was effective in improving the quality of sleep and state anxiety in a hospice.

• Journal of Korean Biological Nursing Science
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• v.17 no.3
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• pp.271-276
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• 2015

Purpose: This study was to evaluate the effects on the heart rate and respiration rate of preterm infants when providing auditory stimulation on them. Methods: The design of this study was a nonequivalent control group pretest-posttest design in a quasi experimental study. Forty preterm infants were assigned to experimental and control groups : 20 in the auditory and 20 in the control group. The data were collected from May 2014 to October. The auditory stimulation was created by using an audio music tape provided 20-minute per day for 7 consecutive days. In data analysis, SPSS WIN 21.0 program was utilized for descriptive statistics, repeated measurement anova and Mann-Whitney. Results: General characteristics of the two groups showed no significant differences, thus two groups were found to be homogenous. There were no significant differences in heart rate and respiration rate between the auditory and control groups. Conclusion: The effect of auditory stimulation for 7 days was not effective in decreasing heart rate or respiration rate in premature infants. Therefore, the type and length of music therapy must be developed for the improvement of vital signs in preterm infants who were hospitalized in a neonatal intensive care unit.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.46 no.5
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• pp.385-392
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• 2018

This paper suggests a new method to estimate the roll and pitch damping moment coefficients of a flying disc through sensor data from the onboard IMU module. This method can be easily performed than wind tunnel or computational fluid dynamics methods because it estimates aerodynamic coefficients simply after accumulating the inertial data through several repeated flight experiments. Estimated coefficients are applied to a simulator which is based on the flight dynamics of a flying disc. Finally, the predicted flight trajectory is compared with the true position provided by GPS, which demonstrated the validity of the proposed estimation method.

• Communications for Statistical Applications and Methods
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• v.23 no.2
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• pp.131-146
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• 2016

In research on behavioral studies, significant attention has been paid to the stage-sequential process for longitudinal data. Latent class profile analysis (LCPA) is an useful method to study sequential patterns of the behavioral development by the two-step identification process: identifying a small number of latent classes at each measurement occasion and two or more homogeneous subgroups in which individuals exhibit a similar sequence of latent class membership over time. Maximum likelihood (ML) estimates for LCPA are easily obtained by expectation-maximization (EM) algorithm, and Bayesian inference can be implemented via Markov chain Monte Carlo (MCMC). However, unusual properties in the likelihood of LCPA can cause difficulties in ML and Bayesian inference as well as estimation in small samples. This article describes and addresses erratic problems that involve conventional ML and Bayesian estimates for LCPA with small samples. We argue that these problems can be alleviated with a small amount of prior input. This study evaluates the performance of likelihood and MCMC-based estimates with the proposed prior in drawing inference over repeated sampling. Our simulation shows that estimates from the proposed methods perform better than those from the conventional ML and Bayesian method.

• Journal of Sensor Science and Technology
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• v.25 no.6
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• pp.431-434
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• 2016

Currently, the radial basis function network (RBFN) and various other neural networks are employed to classify gases using chemical sensors arrays, and their performance is steadily improving. In particular, the identification performance of the RBFN algorithm is being improved by optimizing parameters such as the center, width, and weight, and improved algorithms such as the radial basis function network-stochastic gradient (RBFN-SG) and radial basis function network-normalized stochastic gradient (RBFN-NSG) have been announced. In this study, we optimized the number of centers, which is one of the parameters of the RBFN-NSG algorithm, and observed the change in the identification performance. For the experiment, repeated measurement data of 8 samples were used, and the elbow method was applied to determine the optimal number of centers for each sample of input data. The experiment was carried out in two cases(the only one center per sample and the optimal number of centers obtained by elbow method), and the experimental results were compared using the mean square error (MSE). From the results of the experiments, we observed that the case having an optimal number of centers, obtained using the elbow method, showed a better identification performance than that without any optimization.

• The Korean Journal of Applied Statistics
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• v.26 no.4
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• pp.581-594
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• 2013

A group sequential design can end a clinical trial early if a confirmed efficacy or a futility of study medication is found during clinical trials. Adaptation can adjust the design of clinical trials based on accumulated data. The key to this methodology is considered to control the overall type 1 error rate while maintaining the integrity of clinical trials. The estimation would be more complex and the sample size calculation will be more difficult if the clinical trials have repeated measurement data. Lee et al. (2002) suggested a repeated observation case by using the independent increments properties of the interim test statistics and investigated the properties of the proposed confidence interval based on the stage-wise ordering. This study extend Lee et al. (2002) to adaptive group sequential design. We suggest test statistics for the adaptation as redesigning the second stage of clinical trials and induce the stage-wise confidence interval of parameter of interests. The simulation will help to confirm the suggested method.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.7
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• pp.3213-3218
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• 2012

When patients with advanced breast cancer (ABC) are treated with neoadjuvant chemotherapy (NACT), efficacy is monitored by the extent of tumor shrinkage. Since their publication in 1981, World Health Organization (WHO) guidelines have been widely practiced in clinical trials and oncologic practice, for standardized tumor response evaluation. With advances in cancer treatment and tumor imaging, a simpler criterion based on one-dimensional rather than bi-dimensional (WHO) tumor measurement, named Response Evaluation Criteria in Solid Tumors (RECIST) was introduced in 2000. Both approaches have four response categories: complete response, partial response, stable disease and progressive disease (PD). Bi-dimensional measurement data of 151 patients with ABC were analysed with WHO and RECIST criteria to compare their response categories and inter criteria reproducibility by Kappa statistics. There was 94% concordance and 9/151 patients were recategorized with RECIST including 6/12 PD cases. RECIST therefore under-estimates and delays diagnosis of PD. This is undesirable because it may delay or negate switch over to alternate therapy. Analysis was repeated with a new criteria named RECIST-Breast (RECIST-B), with a lower threshold for PD (${\geq}10%$ rather than ${\geq}20%$ increase of RECIST). This showed higher concordance of 97% with WHO criteria and re-categorization of only 4/151 patients (1/12 PD cases). RECIST-B criteria therefore have advantages of both ease of measurement and calculations combined with excellent concordance with WHO criteria, providing a practical clinical tool for response evaluation and offering good comparison with past and current clinical trials of NACT using WHO guidelines.