• The Journal of Korean Academy of Prosthodontics
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• v.32 no.4
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• pp.593-607
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• 1994

The purpose of this study is to evaluate the effect of the bone morphogenetic protein, bone matrix gelatin and collagen matrix on the amount and shape of generating new bone adjacent to the implant. Implants were inserted in the mandible of adult dogs at 2 months after teeth extraction. Artificial bony defects, 3mm in width and 4mm in depth were made at the mesial and distal side of implant. Experimental groups were divided into three groups ; Group 1 : Defects filled with collagen matrix and bone morphogenetic protein, Group 2 : Defects filled with bone matrix gelatin. Control group : Defects filled with only collagen matrix. After implantation, the animals were sacrificed at 1,3,5 and 10 weeks for light microscopic examination. For the fluorescent microscopic examination. each tertracycline Hcl and calcein were injected at 1, 3, 5, 8 and 10 weeks after implantation. The results obtained were as follows : 1. The molecular weight of bovine BMP was about 18,100 by hydroxyapatite chromatography. 2. Osseointegration was observed in experimental groups 1 & 2, and BMG and BMP had an excellent bone forming capability as a filling materials to the repair of the bone defects. 3. The degree of healing of bone defect area, the experimental group 1 showed more prominent bone formation than control group, and the control group showed fibrous connective tissue between the implant and the bone. 4. In the fluorescent microscopic findings, bone remodelling was observed regenerative lamellar bone at defect area in experimental group 1, and partial remodelling in experimental group 2, In the control group, fibrous connective tissue was observed between the implant and bone surface and sign of remodelling was not apperaed. Above results suggest that BMP has rapid osteoinductive property and can be used clinically as a bone substitute on bone defects around implants.

• Journal of the Korea institute for structural maintenance and inspection
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• v.14 no.3
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• pp.75-82
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• 2010

The static strengths of the existing RC beams were experimentally investigated in this paper to understand the strength characteristics of existing structural members and to get appropriate data in strengthening RC members in the remodelling construction. Ten RC beams were prepared by cutting and extracting directly from the demolition site of apartment housings and tested in order to evaluate the flexural and shear strengths of existing RC beams by their geometric condition. From the test results, it was found that most of the specimens had a sufficient structural capacity except for some special case, for example, specimens with severe cracks or concrete losses caused by improper casting. Therefore, the severely deteriorated members originated from bad concrete casting or careless construction process should be repaired and strengthened in remodelling construction.

• The korean journal of orthodontics
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• v.10 no.1
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• pp.29-36
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• 1980

Inclined plane, one of frequently used orthodontic appliances, may cause posterior displacement of mandible and injure the normal growth of temporomandibular joint. So author carried out the mandibular posterior displacement experimentally induced by inserting inclined plane in the rat incisors in order to investigate the histological reactions occuring in the temporomandibular joint of experimental animals. Following results were obtained. 1. The posterior displacement of condyle resulted in the widening of anterior synovial space with anterior condylar hyperplasia and posterior condylar atrophy. In addition, tissue changes were more severe in young rats than in adult rats. 2. The tissue reactions were localized only to condylar head ana there were no evidence of traumatic features in young rats. In adult rats, hemorrhage was an additional finding 1 week after experiment. 3. The remodelling processes were accompanied by the increasing or reduction of fibrous layer and subsequent replacement by cartilage layer occured massively and abruptly in young rats, it occured slightly and slowly in adult rats. 4. The remodelling process of injured condyle occured from 1 week to 4 weeks after experiment and completed between 8 weeks after experiment.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2002.11a
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• pp.103-109
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• 2002

This research is aiming to specify the requirement of the investment such as initial cost, running cost earning rate to make effective investment considering the purpose of remodeling and economical value of store building enough to meet the initial purpose of remodeling. The review of earning rate for economical evaluation was performed by the on-site auditing on the structure and function of the building and applying the assessment simulation program, which is to find the possible business model to identify the requirement of building owner through case study. After the research, the following results are obtained. First, it is important that many aspects should be carefully analysis and the best method should be selected as characteristics of remodeling can be defer each other in their implementations. Second, though the remodeling of exist buildings to promote the functions has been applied. no suitable assessment tool has bee developed for deciding the level of remodeling in the view of economical efficiency so far. Third, the economical benefit was evaluated by analysing annual earning rate which is applied by investment items and recovery period for the investment. More specific data bate should be established to apply the suggested economic accession in business enough to forecast the future circumstances. More researches should be promoted on this area continuously as well as the integrated economic evaluation of remodeling on existing building.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.3
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• pp.1085-1091
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• 2014

Matrix metalloproteinases (MMPs) are a family of zinc dependent extracellular matrix (ECM) remodelling endopeptidases having the ability to degrade almost all components of extracellular matrix and implicated in various physiological as well as pathological processes. Carcinogenesis is a multistage process in which alteration of the microenvironment is required for conversion of normal tissue to a tumour. Extracellular matrix remodelling proteinases such as MMPs are principal mediators of alterations observed in the microenvironment during carcinogenesis and according to recent concepts not only have roles in invasion or late stages of cancer but also in regulating initial steps of carcinogenesis in a favourable or unfavourable manner. Establishment of relationships between MMP overproduction and cancer progression has stimulated the development of inhibitors that block proteolytic activity of these enzymes. In this review we discuss the MMP general structure, classification, regulation roles in relation to hallmarks of cancer and as targets for therapeutic intervention.

• The korean journal of orthodontics
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• v.19 no.2
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• pp.37-55
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• 1989

The tissue reactions concerned in alveolar bone remodelling at the pressure zones of rat molar periodontium associated with the application of force (15 gm) to the maxillary first molar teeth of the albino rats were studied by the transmission electron microscopy. Osteoclasts referrable to bone resorption were observed thereafter 3 hour survival period and undermining resorption was generated thenceforth 2 day survival period. Bone resorption, reversal zone and new bone formation were simultaneously observed adjacent to the zone of undermining resorption in the 7 day survival period. Osteoclasts with well developed primary lysosome, ruffled border, clear zone, granules and Golgi apparatus were detected at the zone of the bone resorption, and dark and bright cells adjacent to the osteoclasts as well. Mononuclear cells and perpendicularly arranged collagenous fibers were observed in the reversal zone and, on the other hand, osteoblasts with well developed Golgi apparatus and rough endoplasmic reticulum were detected at the zone of bone formation.

• Journal of Agricultural Extension & Community Development
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• v.14 no.2
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• pp.417-436
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• 2007

The purpose of this study was to prepare for developing rural house remodeling techniques utilizing the traditional residence factor. The study was carried out through both literature research and on-site research. The traditional residence space factors were identified through literature research and on-site research was carried out through analysis of the rural house remodeling cases. The results of this study was as follows ; 1) Traditional space factors were derived by literature research i. e. space arrangement (topography, direction, plane arrangement), exterior factors; walls, madang, interior factors; roofs, ondol, floors, colours. 2) The traditional residence factor utilizations of remodeling were applied a result through investigation case and analysis. Five rural houses in Namsa village, Danseong-myeon, Sangcheong-gun, Gyeongsangnam-Do were analyzed as remodeling cases including traditional residence factors. There were limitation of budget problems and material selection in the traditional residence factor utilizations of remodeling. The researchers have chosen target rural houses which applied for traditional residence factors to remodel the rural houses, and the most important factor to consider was harmony with rural unique characteristics. The researchers suggested considerations should be placed on development with energy savings and convenience in rural house remodelling.

• Journal of the Korea institute for structural maintenance and inspection
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• v.11 no.2
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• pp.117-124
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• 2007

An experimental research has been performed to evaluate the load transfer capacity for the planar joints between existing and new slab in an apartment remodelling constructions expecially for enlarging the interior space. Post-installed dowel bars were used as a joint connector. The existing slabs were obtained from the existing apartment housing which will be demolished, and were retrofitted with carbon fiber plate. Test results showed that the planar joints with post-installed dowel bars behaved in full composite modes until ultimate capacity of test specimens, so sufficient ultimate and serviceability performance are confirmed.

• The korean journal of orthodontics
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• v.21 no.3
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• pp.685-699
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• 1991

The purpose of this report is to review vertical dysplasia such as openbite or deep bite in skeletal Class III malocclusion and their treatment modality and to present two cases treated with MEAW. The results obtained were as follows A. Open bite case 1. The treatment time was 3 year 8 months. 2. Upper and lower incisors showed extrusion and especially lower anterior alveolar process showed remodelling. 3. The mesially inclined upper and lower molars were uprighted and especially lower first molars showed extrusion that means remodelling of alveolar bone. 4. Normal overbite and overjet were established. 5. Mandible showed slight clockwise rotation. 6. Maxilla showed slight downward bending of ANS part. 7. Upper lip showed downward drop and lower lip showed retraction and touch between upper and lower lip was established. 8. Tongue posture of post-treatment was more raised than pretreatment. B. Deep bite case 1. The treatment time was 1 year 8 months. 2. Upper incisors showed intrusion and labioversion and lower incisors showed slight intrusion and linguoversion. 3. The lower molars showed distal uprighting and intrusion and upper molars showed mesial movement and extrusion. 4. Normal overbite and overjet were established. 5. Maxilla did not show downward movement. 6. Mandible showed slight clockwise rotation. 7. Lower lip showed retraction and downward drop and upper lip showed downward drop.

• Proceedings of the Korea Concrete Institute Conference
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• 2006.11a
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• pp.25-28
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• 2006

In general, post-installed dowel bars are used as a shear connector to ensure the composite actions between new slabs and existing slabs in an apartment remodelling constructions expecially for enlarging the interior space outward the existing buildings. But, it has not been checked that the connection performance between existing and new slab is satisfactory not only for the structural safety condition but also the for serviceability and dwelling requirements. In this research, an experimental works were presented to evaluate the load transfer capacity for the planar joints between existing and new slab. The existing slabs were obtained from the existing apartment housing which will be demolished, and were retrofitted with carbon fiber plate. Test results showed that the planar joints with post-installed dowel bars behaved in full composite modes until ultimate capacity of test specimens, so sufficient ultimate and serviceability performance are confirmed.