• Title/Summary/Keyword: region-wide

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Quantitative Trait Loci Affecting Rous Sarcoma Virus Induced Tumor Regression Trait in F2 Intercross Chickens

  • Uemoto, Y.;Saburi, J.;Sato, S.;Odawara, S.;Ohtake, T.;Yamamoto, R.;Miyata, T.;Suzuki, K.;Yamashita, H.;Irina, C.;Plastow, G.;Mitsuhashi, T.;Kobayashi, E.
    • Asian-Australasian Journal of Animal Sciences
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    • v.22 no.10
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    • pp.1359-1365
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    • 2009
  • We performed a genome-wide linkage and quantitative trait locus (QTL) analysis to confirm the existence of QTL affecting Rous Sarcoma Virus (RSV) induced tumor regression, and to estimate their effects on phenotypic variance in an F2 resource population. The F2 population comprised 158 chickens obtained by crossing tumor regressive White Leghorn (WL) and tumor progressive Rhode Island Red (RIR) lines was measured for tumor formation after RSV inoculation. Forty-three tumor progressive and 28 tumor regressive chickens were then used for genome-wide linkage and QTL analysis using a total of 186 microsatellite markers. Microsatellite markers were mapped on 20 autosomal chromosomes. A significant QTL was detected with marker LEI0258 located within the MHC B region on chromosome 16. This QTL had the highest F ratio (9.8) and accounted for 20.1% of the phenotypic variation. Suggestive QTL were also detected on chromosomes 4, 7 and 10. The QTL on chromosome 4 were detected at the 1% chromosome-wide level explaining 17.5% of the phenotypic variation, and the QTLs on chromosome 7 and 10 were detected at the 5% chromosome-wide level and explained 11.1% and 10.5% of the phenotypic variation, respectively. These results indicate that the QTLs in the non-MHC regions play a significant role in RSV-induced tumor regression. The present study constitutes one of the first preliminary reports in domestic chickens for QTLs affecting RSV-induced tumor regression outside the MHC region.

Investigation of Pressure Drop for a Pseudo-plastic Fluid Flow in Isosceles Triangle Pipes (이등변삼각형 단면을 갖는 파이프 내의 Pseudo-Plastic 유체유동에 대한 압력강하의 연구)

  • Lee, D.R.
    • Journal of Power System Engineering
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    • v.13 no.2
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    • pp.30-35
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    • 2009
  • Numerical Calculations for dimensionless pressure drop (friction factor times Reynolds number) have been obtained for fully developed laminar flow of MPL(Modified Power Law) fluid in isosceles triangle pipes. The solutions are valid for Pseudoplastic fluids over a wide range from Newtonian behavior at low shear rates through transition region to power law behavior at higher shear rates. The analysis identified a dimensionless shear rate parameter which for a given set of operating conditions specifies where in the shear rate range a particular system is operating, i.e., Newtonian, transition or power law region. The numerical calculation data of the dimensionless pressure drop for the Newtonian and power law regions are compared with previously published asymptotic results presenting within 0.16 % in Newtonian region and 2.98 % in power law region.

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Alveolar ridge expansion-assisted orthodontic space closure in the mandibular posterior region

  • Ozer, Mete;Akdeniz, Berat Serdar;Sumer, Mahmut
    • The korean journal of orthodontics
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    • v.43 no.6
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    • pp.302-310
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    • 2013
  • Orthodontic closure of old, edentulous spaces in the mandibular posterior region is a major challenge. In this report, we describe a method of orthodontic closure of edentulous spaces in the mandibular posterior region accelerated by piezoelectric decortication and alveolar ridge expansion. Combined piezosurgical and orthodontic treatments were used to close 14- and 15-mm-wide spaces in the mandibular left and right posterior areas, respectively, of a female patient, aged 18 years and 9 months, diagnosed with skeletal Class III malocclusion, hypodontia, and polydiastemas. After the piezoelectric decortication, segmental and full-arch mechanics were applied in the orthodontic phase. Despite some extent of root resorption and anchorage loss, the edentulous spaces were closed, and adequate function and esthetics were regained without further restorative treatment. Alveolar ridge expansion-assisted orthodontic space closure seems to be an effective and relatively less-invasive treatment alternative for edentulous spaces in the mandibular posterior region.

A Study on the Establishment of the Metropolitan Transportation Area (광역 교통권 설정에 관한 연구)

  • 박병호
    • Journal of Korean Society of Transportation
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    • v.8 no.2
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    • pp.55-66
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    • 1990
  • The research deals with the establishment of transportation areas in the metropolitan cities. The purpose is three-fold ; 1) to review the existing literature : 2) to analyze the commuting (work and school) pattern and interregional movement pattern of passengers and freights ; 3) to establish the metropolitan transportation area based on the above analyses. The transportation area is defined by the analysis of trip pattern to the center city of each metropolitan area. The detailed indices for establishment are selected by the rank-size and time-distance analyses. For the operational purpose, the study defines 3 different transportation areas as follows : the first transportation area means the directly effecting region of the center city ; the second means the region with many reverse trips and development potentials ; and the third means the indirectly effecting region. It can be concluded that the first transportation area includes 10 cities and 5 counties in Seoul metropol tan region, Yangdsan-Gun, Kimhae-Gun and Kimhae-Si in Busan, Dalsung-Gun, Chilgok-Gun and Kyungsan-Gun in Daegu, Hwasung-Gun and Raju-Gun in Kwangju, and Daeduk-Gun in Daejun. These results could be expected to have many implications for the establishment of area-wide public transportation network, the metropolitan transportation decision-making bodies and others.

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NASA Model Deviation Correction for Accuracy Improvement of Land Surface Temperature Extraction in Broad Region (NASA 모델의 편차보정에 의한 광역지역의 지표온도산출 정확도 향상)

  • Um Dae-Yong;Park Joon-Kyu;Kim Min-Kyu;Kang Joon-Mook
    • Proceedings of the Korean Society of Surveying, Geodesy, Photogrammetry, and Cartography Conference
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    • 2006.04a
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    • pp.281-286
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    • 2006
  • In this study, acquired time series Landsat TM/ETM+ image to extract land surface temperature for wide-area region and executed geometric correction and radiometric correction. And extracted land surface temperature using NASA Model, and I achieved the first correction by perform land coverage category for study region and applies characteristic emission rate. Land surface temperature that acquire by the first correction analyzed correlation with Meteorological Administration's temperature data by regression analysis, and established correction formula. And I wished to improve accuracy of land surface temperature extraction using satellite image by second correcting deviations between two datas using establishing correction formula. As a result, land surface temperature that acquire by 1,2th correction could correct in mean deviation of about ${\pm}3.0^{\circ}C$ with Meteorological Administration data. Also, could acquire land surface temperature about study region by relative high accuracy by applying to other Landsat image for re-verification of study result.

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Ductility Capacity of Slender-Wind R/C Walls (긴 세장한 R/C 벽체의 연성능력)

  • 홍성걸
    • Proceedings of the Earthquake Engineering Society of Korea Conference
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    • 2000.04a
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    • pp.202-212
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    • 2000
  • This study investigates the ductility capacity of slender-wide reinforced concrete walls under predominant flexural moment loading. The experimental work for this study aims to provide design guidelines for bar detailing in critical regions under compressive stress in particular in case of slender-wide RC walls. According to the experimental observation the Bernoulli hypothesis of linear strain distribution is no longer valid and the ultimate compressive strain of concrete is significantly reduced, It is postulated that the nonlinear strain distribution causes the concentrated compressive stressed region and hence the premature crushing failure at the toe of walls. The reduced ultimate strain and nonlinear strain distribution need transverse reinforcement for confinement and more realistic models for the strength and displacement estimation of slender-wide RC wall.

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Reconfigurable Selective Harmonic Elimination Technique for Wide Range Operations in Asymmetric Cascaded Multilevel Inverter

  • Kavitha, R;Rani, Thottungal
    • Journal of Power Electronics
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    • v.18 no.4
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    • pp.1037-1050
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    • 2018
  • This paper presents a novel reconfigurable selective harmonic elimination technique to control harmonics over a wide range of Modulation Indexes (MI) in Multi-Level Inverter (MLI). In the proposed method, the region of the MI is divided into various sectors and expressions are formulated with different switching patterns for each of the sectors. A memetic BBO-MAS (Biogeography Based Optimization - Mesh Adaptive direct Search) optimization algorithm is proposed for solving the Selective Harmonic Elimination - Pulse Width Modulation (SHE-PWM) technique. An experimental prototype is developed using a Field Programmable Gate Array (FPGA) and their FFT spectrums are analyzed over a wide range of MI using a fluke power logger. Simulation and experimental results have validated the performance of the proposed optimization algorithms and the reconfigurable SHE-PWM technique. Further, the sensitivity of the harmonics has been analyzed considering non-integer variations in the magnitude of the input DC sources.

Pretilt Angle Dependent Electro-Optic Characteristics of the Fringe-Field Switching mode using the Liquid Crystal with Positive Dielectric Anisotropy (유전율 이방성이 양인 액정을 이용한 프린지 필드 구동형 모드에서 프리틸트각 변화에 따른 전기-광학 특성)

  • 정태봉;임영진;안명환;이승희
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.17 no.3
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    • pp.311-318
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    • 2004
  • We have studied electro-optic characteristics as a function of pretilt angle ($\theta$$_{p}$) in the fringe-field switching (FFS) mode using the LC with positive dielectric anisotropy. When $\theta$$_{p}$ is increased from 0$^{\circ}$ to 20$^{\circ}$, a maximum transmittance and an operating voltage are obviously decreased. In the viewing angle characteristics, the cell with low pretilt angle has a wide region for the contrast ratio greater than 5 and has a best luminance uniformity. Therefore, in the FFS device, a low pretilt angle is favored for high transmittance and wide viewing angle.gle.

Comparison of Erythrocyte Traits Among European, Japanese and Korean

  • Kwon, Ji-Sun;Kim, Sang-Soo
    • Genomics & Informatics
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    • v.8 no.3
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    • pp.159-163
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    • 2010
  • Erythrocyte traits are heritable and indirect indicators of blood diseases caused by erythrocyte, but their genetic factors are largely unknown. So we performed genome-wide association study in 8,842 Korean individuals to identify genetic factors influencing erythrocyte traits. We identified 40 associations for three erythrocyte traits at genome-wide significance levels (p < $1{\times}10^{-6}$). We compared these associated loci with those reported in genome-wide association studies of European and Japanese. Our findings include previously identified loci(HBS1L-MYB, TMPRSS6, USP49 and CCND3) in other studies and novel associations (MRDS1/OFCC1, CSDE1, NRAS and 8 other loci). For example, SNP rs4895440 of HBS1L-MYB intergenic region on chromosome 6q23.3 is one of the most associations influencing erythrocyte traits (p=$8.33{\times}10^{-27}$).

The Area-wide Economic Regions in Korea: Orthodox New Regionalism or Politically-inflicted Regionalism?

  • Cho, Cheol-Joo
    • World Technopolis Review
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    • v.1 no.4
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    • pp.240-255
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    • 2013
  • The recent interest in regions represents a rise of the new regionalism. Three competing theories provide the frameworks of explaining the ascendance of regions as the meaningful vessel of territorial economic and political processes. They are the orthodox new regionalism, the new politics of scale, and the relational topology of networked actors. Referring to these theories, this paper assesses the establishment of cross-provincial Area-wide Economic Regions (AERs) in Korea. The findings indicate that AERs represent a radical shift to a new regionalism. However, it is misconceived to see their ascendance as the orthodox new regionalism, as they marginally fit the hollowing-out of the state thesis. Nor they show distinct features to which the politically-inflicted regionalism is attributed. In consequence, AERs represent the emergence of a new regionalism that is consequent of the unique politico-economic context of Korea, say, a most centralized state-society combined with the neoliberalizing policy process emanating from the globalization pressures.