• Title/Summary/Keyword: reducing efficacy

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Efficacy of Pesticides and Growth Hormones against Root Disease Complex of Mulberry (Morus alba L.)

  • Naik, Vorkady Nishitha;Sharma, Dinesh Dutta
    • International Journal of Industrial Entomology and Biomaterials
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    • v.15 no.2
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    • pp.101-106
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    • 2007
  • During mulberry cultivation, root disease complex caused by the association of root knot nematode (Meloidogyne incognita) with root rot pathogens like Fusarium solani and Botryodiplodia theobromae poses serious loss in leaf production. Therefore, an attempt was made to assess the efficacy of eight pesticides (Metayalaxyl+Mancozeb, Thiophanate methyl, Mancozeb, Bitertanol, Phenomiphos, Phorate, Thionazin & Carbofuran) and two growth hormones (Salicylic acid and Indole 3 acetic acid) at 0.1 and 0.2% concentrations under in vitro conditions against nematode (hatching of eggs and mortality of larvae) and root rot pathogens (poisoned food technique) for short listing the treatments to develop an IDM strategy. Results revealed that among the pesticides and growth hormones, Carbofuran followed by Salicylic acid were found to be effective at 0.2% concentration against both nematode and pathogenic fungi. Both the chemicals inhibited the hatching of nematode eggs by 83.5-78.9% and 80-76% larval mortality over the control and reduced the mycelial growth of both the pathogenic fungi to an extent of 75.5-77.8%. Though Mancozeb inhibited both the pathogenic fungi strongly (77-80%), it did not show any effectiveness against nematode. The rest of the chemicals were found either moderately or poorly effective in reducing the growth of pathogenic fungi, hatching of nematode eggs and enhancing the mortality of larvae. The two effective chemicals viz., Carbofuran and Salicylic acid, which rated as strong inhibitors against both nematode and pathogenic fungi, can be exploited in developing an IDM package as one of the component for better management of root disease complex in mulberry.

Immunogenicity and Protective Efficacy of a Dual Subunit Vaccine Against Respiratory Syncytial Virus and Influenza Virus

  • Park, Min-Hee;Chang, Jun
    • IMMUNE NETWORK
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    • v.12 no.6
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    • pp.261-268
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    • 2012
  • Respiratory syncytial virus (RSV) and influenza virus are the most significant pathogens causing respiratory tract diseases. Composite vaccines are useful in reducing the number of vaccination and confer protection against multiple infectious agents. In this study, we generated fusion of RSV G protein core fragment (amino acid residues 131 to 230) and influenza HA1 globular head domain (amino acid residues 62 to 284) as a dual vaccine candidate. This fusion protein, Gcf-HA1, was bacterially expressed, purified by metal resin affinity chromatography, and refolded in PBS. BALB/c mice were intranasally immunized with Gcf-HA1 in combination with a mucosal adjuvant, cholera toxin (CT). Both serum IgG and mucosal IgA responses specific to Gcf and HA1 were significantly increased in Gcf-HA1/CT-vaccinated mice. To determine the protective efficacy of Gcf-HA1/CT vaccine, immunized mice were challenged with RSV (A2 strain) or influenza virus (A/PR/8/34). Neither detectable viral replication nor pathology was observed in the lungs of the immune mice. These results demonstrate that immunity induced by intranasal Gcf-HA1/CT immunization confers complete protection against both RSV and homologous influenza virus infection, suggesting our Gcf-HA1 vaccine candidate could be further developed as a dual subunit vaccine against RSV and influenza virus.

Three Case Reports of Avascular Necrosis of Femur Head Have Treated by Acupotomy (침도요법을 통한 대퇴골두 무혈성 괴사환자 3명에 대한 증례보고)

  • Kim, Sung-Soo;Park, Se-Woon;Moon, Hyo;Lee, Geon-Mok
    • Journal of Acupuncture Research
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    • v.28 no.5
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    • pp.143-151
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    • 2011
  • Objectives : The purpose of this study is to report the effect of acupotomy for patient with avascular necrosis(AVN) of femur head. Methods : Three patient who had been diagnosed as AVN participated in this study. The patient treated by acupotomy therapy. After the treatment, the patient was measured by visual analogue scale(VAS), Harris hip score and five likert scale Results : The patient informed the researcher of reduced pain and improved range of movement after the conduct of acupotomy therapy. The efficacy of acupotomy treatment was reaffirmed by the results of the VAS, physical examination (ROM, Patrcik sign), Harris hip score. Conclusions : Acupotomy therapy on AVN of femur head shows the efficacy in reducing pain and improving movement.

Efficacy of Soil Amendment with Medicinal Plant Materials for the Control of Root-knot Nematode (Meloidogyne incognita) in Tomato

  • Kim, Young-Ho;Hafeez, U.Khan;Kim, Jung-Ho;Jeon, Yong-Ho;Lee, Eun-Jung;Chang, Sung-Pae
    • The Plant Pathology Journal
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    • v.19 no.3
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    • pp.138-142
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    • 2003
  • Soil amendments with oriental herbal medicines such as fruit of Anethum graveolens, flower buds of Syzygium aromaticum, rhizome of Cnidium officinale, rhizome of Coptis chinensis, root bark of Paeonia suffructicosa, stem bark of phellodendron amurense, and stem bark of Cinnamomum cassia at the rate of 0.2% (weight by volume of soil) significantly reduced Meloidogyne incognita infection (root gall formation) of tomato seedlings compared with the control. The most effective treatments were root bark of p. suffructicosa and stem bark of C. cassia as they gave minimum numbers of galls on tomato roots (4.7% and 8.9%, respectively, relative to control) as compared to other treatments. Another study with root bark of p. suffructicosa and C. cassia at different application doses also showed consistent results in reducing gall number. The control efficacy decreased as the application doses were lower-ed, indicating their dose-dependent control activities. These treatments significantly enhanced aboveground plant growths (total masses).

Efficacy of Carcass Electrical Stimulation in Meat Quality Enhancement: A Review

  • Adeyemi, Kazeem Dauda;Sazili, Awis Qurni
    • Asian-Australasian Journal of Animal Sciences
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    • v.27 no.3
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    • pp.447-456
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    • 2014
  • The use of electrical stimulation (ES) as a management tool to improve meat quality and efficiency of meat processing is reviewed. The basis of the efficacy of ES is its ability to fast track postmortem glycolysis, which in turn stimulates myriad histological, physical, biochemical, biophysical and physiological changes in the postmortem muscle. Electrical stimulation hastens the onset and resolution of rigor mortis thereby reducing processing time and labor and plays a vital role in improving meat tenderness and other meat quality traits. However, ES may have negative impacts on some meat quality traits such as color stability and water holding capacity in some animals. Electrical stimulation is not an end in itself. In order to achieve the desired benefits from its application, the technique must be properly used in conjunction with various intricate antemortem, perimortem and postmortem management practices. Despite extensive research on ES, the fundamental mechanisms and the appropriate commercial applications remained obscured. In addition, muscles differ in their response to ES. Thus, elementary knowledge of the various alterations with respect to muscle type is needed in order to optimize the effectiveness of ES in the improvement of meat quality.

A Study on Statistical Approach for Nonlinear Image Denoising Algorithms (비선형 영상 잡음제거 알고리즘의 통계적 접근 방법에 관한 연구)

  • Hahn, Hee-Il
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.12 no.1
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    • pp.151-156
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    • 2012
  • In this paper robust nonlinear image denoising algorithms are introduced for the distribution which is Gaussian in the center and Laplacian in the tails. The distribution is known as the least favorable ${\epsilon}$-contaminated normal distribution that maximizes the asymptotic variance. The proposed filter proves to be the maximum likelihood estimator under the heavy-tailed Gaussian noise environments. It is optimal in the respect of maximizing the efficacy under the above noise environment. Another filter for reducing impulsive noise is proposed by mixing with the myriad filter to propose an amplitude-limited myriad filter. Extensive experiment is conducted with images corrupted with ${\alpha}$-stable noise to analyze the behavior and performance of the proposed filters.

A Study on the Development and Effects of a Parenting Training Program for Improving Parent-Child Relationships in Multi-cultural Families (유아기 자녀를 둔 다문화가족 부모자녀관계 증진을 위한 부모교육프로그램 개발 및 효과성 연구)

  • Min, Sung-Hye;Kim, Kyung-Eun;Kim, Lee-Jin
    • Korean Journal of Child Studies
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    • v.32 no.1
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    • pp.31-49
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    • 2011
  • This study centred around the development of a parenting training program for improving parent-child relationships in multi-cultural families and to examine the effects of the program. The goal of this program was to improve parent-child relationships in multi-cultural families. The program consists of 8 sessions and each session employs a variety of activities and teaching methods to help multi-cultural mothers to become more involved in the a program. The participants were 12 mothers of multi-cultural backgrounds in Seoul and Asan city. There 12 mothers were assigned to the experimental group participated in this program for a total of 8 sessions. Data were analyzed according to frequencies, percentiles, means, standard deviations, and paired t-test. The results of this study indicated that this parenting training program for improving parent-child relationships was effective in improving multi-cultural mother's parenting efficacy and reducing their parenting stress.

Biocontrol of Potato White Mold Using Coniothyrium minitans and Resistance of Potato Cultivars to Sclerotinia sclerotiorum

  • Ojaghian, Mohammad Reza
    • The Plant Pathology Journal
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    • v.26 no.4
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    • pp.346-352
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    • 2010
  • This study was conducted in Bahar and Lalehjin, Hamadan, Iran to assess the biocontrol efficacy of Coniothyrium minitans Campbell against potato white mold caused by Sclerotinia sclerotiorum (Lib.) de Bary under field and greenhouse conditions. In addition, the resistance of common potato cultivars against S. sclerotiorum was determined in a greenhouse experiment. After straw inoculation of six potato cultivars (Pashandi, Istambouli, Agria, Marfauna, Alpha and Spartaan) with S. sclerotiorum, the least disease severity was observed in Spartaan and Marfauna. Agria showed the most susceptibility to S. sclerotiorum. Compared with the healthy control, different concentrations of C. minitans conidia ($10^7$, $10^8$ and $10^9$ conidia/mL) reduced disease severity under greenhouse condition, and a concentration $10^9$ was the most effective treatment. During 2008 and 2009, four field trials were conducted to evaluate the efficacy of C. minitans in different soil and aerial applications on disease incidence of potato white mold. In 2008, soil application of $Contans^{(R)}$ WG (a commercial product of C. minitans) showed the greatest biocontrol capacity whereas soil application of solid-substrate C. minitans was found inferior when compared with other treatments in both Bahar and Lalehjin field sites. In 2009, benomyl application was the most effective treatment in reducing disease incidence in both tested field sites.

Comparative evaluation of efficacy of Physics Forceps versus conventional forceps in pediatric dental extractions: a prospective randomized study

  • Elicherla, Sainath Reddy;Bandi, Sujatha;Nunna, Mahesh;Saikiran, Kanamarlapudi Venkata;Sahithi, Varada;Nuvvula, Sivakumar
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.21 no.6
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    • pp.547-556
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    • 2021
  • Background: This study aimed to determine the efficacy of Physics Forceps in pediatric dental extractions. Methods: This was a double-blind, randomized controlled trial with a parallel-arm design and identical allocation ratio (1:1). Children (n=104) were randomly divided into two groups for extraction of mandibular primary teeth (group I: Physics Forceps; group II: conventional forceps). The outcome variables assessed in the study were the time taken for extraction, pre- and postoperative anxiety (using RMS pictorial scale), incidence of fractured teeth, and postoperative pain on the first and third days (using the Wong-Baker faces pain scale). Results: A significant reduction (P < 0.001) in intraoperative time, anxiety, and incidence of tooth fracture was confined to group I. The pain significantly reduced from the first to the third postoperative day in both groups, but the mean reduction in RMS scores in the physics forceps group was far better than that in the conventional forceps group. Conclusion: Physics Forceps aid in extraction of primary teeth with minimal trauma to supporting structures, as well as reducing anxiety in the pediatric population.

Non-inferiority study of the efficacy of two hyaluronic acid products in post-extraction sockets of impacted third molars

  • Yang, Hyunwoo;Kim, Junghun;Kim, Jihong;Kim, Dongwook;Kim, Hyung Jun
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.42
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    • pp.40.1-40.5
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    • 2020
  • Background: Hyaluronic acid (HA) is well known to exert an anti-inflammatory effect during oral wound healing and is commonly applied after tooth extraction. However, no double-blind randomized controlled study comparing two hyaluronate mouthwash products has been conducted so far. The aim of this study was to comparatively analyze the efficacy of Mucobarrier® and Aloclair® in terms of clinical symptoms. Results: A total of 112 patients were randomly assigned to assess the degree of discomfort, pain reduction, redness, burning sensation, and swelling between two groups on the day of surgery and 7 days later in a double blind test, with a total 56 Aloclair patients and 56 Mucobarrier patients. There was no statistically significant difference in the overall discomfort, degree of pain reduction, redness, burning sensation, and swelling between the Mucobarrier and Aloclair groups. Conclusion: The local application of hyaluronic acid mouth wash after wisdom tooth extraction is beneficial in reducing overall discomfort and pain reduction, and the clinical utility of Mucobarrier® is no different from Aloclair®. Trial registration: Institutional Review Board of Yonsei University College of Dentistry, 2-2018-0036. Registered 10 September 2018-prospectively registered, https://eirb.yuhs.ac/