• 한국환경보건학회지
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• 제21권3호
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• pp.48-55
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• 1995

This study was performed to investigate the inhibitory effect of Aloe vera on the growth and aflatoxin production of Aspergillus parasiticus. Spore suspension of A. parasiticus ATCC 15517 was inoculated on the yeast-extract sucrose broth containing 0.1%, 0.5%, 1.0% and 10.0% of chloroform extract of Aloe vera and then incubated at 30$\circ$C for 7 days. Mycelial weight was 160.7 mg/5ml in control group and decreased by the addition of the extract with no significance. The mold caused decrease in pH of the media with and without the extract. pH in the group contained 10.0% of the extract showed significantly higher value of 5.10 than that of 4.90 in control group (p<0.05). Fluorescence spots of four aflatoxins were observed under the 365 nm of UV light after extraction of the media and TLC. In the result of separation and determination by HPLC, the aflatoxins were produced in the order of $B_1, G_1, B_2$ and $G_2$ in all groups. Production of aflatoxins $B_1, B_2$ and $G_1$ was reduced by the addition of the extract and decreased as amount of the extract increased. The production of aflatoxins $B_1$ and $B_2$ significantly reduced when the media contained more than 1.0% of the extract, and $G_1$ more than 0.5%, respectively(p<0.05). No reduction and no significant difference among groups were observed in case of aflatoxin $G_2$. With the above result, the extract of Aloe vera reduced the production of aflatoxin by A. parasiticus though it did not inhibit mycelial growth.

• 대한가정학회지
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• 제26권1호
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• pp.51-59
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• 1988

In the present study, an attempt was made to observe the effect of calcium-sources and preservatives on Kimchi fermentation. After pre-fermentation at room temperature for 16 hours, each Kimchi was stored at 4$^{\circ}C$. Changes of vitamin contents(vitamin C, thiamin, riboflavin and $\beta$-carotene) during the fermentation of Kimchi were determined. It was also attempt to relate the fermentation of Kimchi with the changes in chemical and organoleptic characteristics, such as pH, total acidity and reducing sugar. The findings were summarized as follows; 1. During Kimchi fermentation, the pH decreased steady and total acidity increased slowly in the follow order: K-Sorbate+acetic acid, k-Sorbate, Ca-Lactate and Control. the lower of pH and the higher of total acidity, the less of reducing sugar was remained. 2. changes of total vitamin C and reduced ascorbic acid contents during the Kimchi fermentation did not differ significantly from each other. At the begining of fermentation, Kimchi samples contained 20~25mg/100g of total vitamin C and 5~14 mg/100g of reduced ascorbic acid. In the final stage, however, 15~19 mg/100g of total vitamin C and 1~3 mg/100g of reduced ascorbic acid were remained. 3. The contents of thiam in and riboflavin were 30 to 42 meg/100g and 50 to 67 meg/100g at the initial stage, respectively. They increased with the degree of maturity (approximately 2 times of the content of the initial stage) and then gradually decreased. The content of $\beta$-carotene was found to be decreased with the degree of maturity. 4. The results of sensory evaluation indicated that Kimchi added with Ca-Carbonate, Ca-Carbonate+acetic acid and Ca-lactate were better than Control.

• Archives of Pharmacal Research
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• 제21권6호
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• pp.683-687
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• 1998

We have examined in vitro and in vivo radioprotective effects of a well-known thiol-containing compound, dithiothreitol (DTT). The treatment of both 0.5 and 1mM of DTT significantly increased clonogenic survival of ${\gamma}$-ray irradiated Chinese hamster (V79-4) cells. In order to investigate the possible radioprotective mechanism of DTT, we measured gamma-ray induced chromosome aberration by micronucleus assay. In the presence of 0.5mM or 1mM DTT, the frequencies of micronuclei were greatly reduced in all dose range examined (1.5-8 GY). Slightly higher reduction in micronucleus formation was observed in 1mM DTT-treated cells than in 0.5mM DTT-treated cells. In addition, incubation with both 0.5 and 1mM of DTT prior to gamma-ray irradiation reduced nucleosomal DNA fragmentation at about same extent, this result suggests that treatment of DTT at concentrations of 0.5 and 1mM reduced radiation-induced apoptosis. In vivo experiments, we also observed that DTT treatment reduced the incidence of apoptotic cells in mouse small intestine crypts. In irradiated control group 4.4${\pm}$0.5 apoptotic cells per crypt were observed. In DTT-administered and irradiated mice, only 2.1${\pm}$0.4 apoptotic cells per crypt was observed. In vitro and in vivo data obtained in this study showed that DTT reduced radiation-induced damages and it seems that the possible radioprotective mechanisms of action of DTT are prevention of chromosome aberration.

• Investigative Magnetic Resonance Imaging
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• 제22권1호
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• pp.26-36
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• 2018

Purpose: Children born with single ventricle physiology demonstrate poor growth rate and suffer from malnutrition, which lead to increased morbidity and mortality in this population. We assume that an anabolic steroid, oxandrolone, will promote growth in these infants by improving myocardial energy utilization. The purpose of this paper is to study the efficacy of oxandrolone on myocardial energy consumption in these infants. Materials and Methods: We modeled single ventricle physiology in a lamb by prenatally shunting the aorta to the pulmonary artery and then postnatally, we monitored cardiac energy utilization by quantitatively measuring the first order reaction rate constant, $k_f$ of the creatine-kinase reaction in the heart using magnetization transfer $^{31}P$ magnetic resonance spectroscopy, home built $^1H/^{31}P$ transmit/receive double tuned coil, and transmit/receive switch. We also performed cine MRI to study the structure and dynamic function of the myocardium and the left ventricular chamber. The spectroscopy data were processed using home-developed python software, while cine data were analyzed using Argus software. Results: We quantitatively measured both the first order reaction rate constant and ejection fraction in the control, shunted, and the oxandrolone-treated lambs. Both $k_f$ and ejection fraction were found to be more significantly reduced in the shunted lambs compared to the control lambs, and they are increased in oxandrolone-treated lambs. Conclusion: Some improvement was observed in both the first order reaction rate constant and ejection fraction for the lamb treated with oxandrolone in our preliminary study.

• 전력전자학회:학술대회논문집
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• 전력전자학회 2003년도 춘계전력전자학술대회 논문집(1)
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• pp.485-489
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• 2003

This paper presents the method of speed measurement for permanent magnet synchronous motor(PMSM) with the full-order observer using reduced-order state equation. This Is able to improve the operating performance at low speed. Therefore, by the proposed technique, a low resolution encoder can be used. Because it make the system improve the performance of speed response. The proposed method is verified to simulation and experiments.

• 전자공학회논문지S
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• 제34S권2호
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• pp.21-32
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• 1997

This paper proposes an elliptical world-modeling mehtrod in order to secure the safety of the mobile robot from the unreliability of ultrasonic sensors and to estimate the lateral orientation of the detected objects. This method is advnatageous because the total amount of data that the robot utilizes is reduced when historical and new data are clusterd during each sensing period and also because the objects in the environment can be almost exactly recognized. This paper also proposes a new local path planning algorithm which is divided into four different situations and gudies the robot through the safe local path using dat acollected in elliptical form. This algorithm can help the AMR navigate by allowing it to sum up the virtual vector forces made form the ellipses in order to select a safe subgoal. This local path plannin gmehtod using the elliptical world model has been proved by several navigation experiments.

• 대한안전경영과학회지
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• 제9권3호
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• pp.119-125
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• 2007

As competition in manufacturing enterprise is contested, the scope of safely production planning, manufacturing enterprise should ensure, has been reduced. The more upstream of SCM, the more reduction of scope of production planning. As a result, order fluctuation is more sharply contested. Through improving the logistics network, it is best way that the end user's demand information is conveyed to upstream of SCM, but it is difficult in fact. In this paper, it mention the way of robustic adjustment, in the suppliers' point of view, the end user's demand information is dammed up, as they postpone responding the customer's order as a possible. And it will show the result of appling the way, as a case study.

• 한국공작기계학회:학술대회논문집
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• 한국공작기계학회 1998년도 춘계학술대회 논문집
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• pp.148-153
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• 1998

In order to control thermal deformation of machine origin of machine tools due to internal and external heat sources, the real-time compensation system has been developed. First, GMDH models were constructed to estimate thermal deformation of machine origin for a vertical machining center through the measurement of deformation data and temperature data of specific points on the machine tool. Thermocouples and gap sensors are used respectively for measurement. These models are nonlinear equations with high-order polynomials and implemented in a multilayered perceptron type network structure. Secondly, work origin shift method were developed by implementing digital I/O interface board between CNC controller and IBM-PC. The work origin shift method is to shift the work origin by the compensation amounts which is calculated by pre-established GMDH model. From the experimental result, thermal deformation of machine origin was reduced to below $\pm$5${\mu}{\textrm}{m}$.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2001년도 하계학술대회 논문집 D
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• pp.1999-2001
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• 2001

The infinite time optimum to regulate the problem of weakly coupled bilinear systems with a quadratic performance criterion is obtained by a sequence of algebraic Lyapunov equations. The new approach is based on the successive approximations. In particular, the order reduction is achieved by using suitable state transformation so that the original Lyapunov equations are decomposed into the reduced-order local Lyapunov equations. The proposed algorithms not only solve optimal control problems in the weakly coupled bilinear system but also reduce the computation time. This paper also includes an example to demonstrate the procedures.

• Journal of Power Electronics
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• 제12권5호
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• pp.689-698
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• 2012

This paper investigates the effects of applying different input current waveshapes on the performance of a continuous-conduction-mode (CCM) power-factor-correction (PFC) boost pre-regulator. It is found that the output voltage ripple of the pre-regulator can be reduced if the input current is modified to include controlled amount of higher order harmonics. This finding allows us to balance the performance of output regulation and the harmonic current emission when coming to the design of the pre-regulator. An experimental PFC boost pre-regulator prototype is constructed to verify the analysis and show the benefit of the pre-regulator operating with input current containing higher order harmonics.