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Effect of Korean Red Ginseng on Artificial Sand Dust (ASD) Induced Allergic Lung Inflammation

  • Kim, Jung-Ha;Lee, Tae-Jin;Im, Jee-Aee;Lee, Duk-Chul
    • Biomedical Science Letters
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    • v.20 no.3
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    • pp.173-179
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    • 2014
  • Asian sand dust is known to promote various respiratory symptoms or disorders. For the prevention of harmful health effects by Asian sand dust, the best strategy is known to avoid or reduce exposure to the Asian sand dust. Several studies have shown that Korean red ginseng (RG) has anti-inflammatory and anti-allergic effects. The study aimed to clarify the effect of Korean red ginseng intake on lung inflammation responses to artificial sand dust (ASD) similar to Asian sand dust. BALB/c mice were divided into five groups (n=12) of control (saline), ovalbumin (OVA), OVA with ASD, OVA plus RG with ASD, and OVA plus dexamethasone (DEXA) with ASD. Histopathologic evaluation of lung was conducted. Interleukin (IL)-5, IL-12, interferon (IFN)-${\gamma}$, IL-13, monocyte chemotactic protein (MCP)-1, and eotaxin within bronchoalveolar lavage (BAL) fluid were measured by ELISA. OVA+ASD group significantly increased concentrations of IL-5, IL-13, MCP-1, and eotaxin (P<0.01) compared to the control. OVA+ASD+RG group showed significant decreased levels of IL-2, IL-13, MCP-1 and eotaxin (P<0.01) compared with OVA+ASD. Between RG and DEXA treatment groups, there was no significant difference in all cytokines and chemokines. The inflammatory cells were significantly decreased in treatment groups with RG or DEXA compared to OVA+ASD group. This study suggests a beneficial effect of Korean RG administration in preventing inflammation of lung resulting from Asian sand dust.

Characteristics and HMG-Co A Reductase Inhibitory Activity of Fermented Red Pepper Soybean Paste(Kochujang) Prepared from Red-Rice and Barley. (홍국과 보리를 이용하여 제조한 고추장의 특성과 HMG-Co A Reductase 저해활성)

  • Hyun, Kwang-Uk;No, Jae-Duck;Lim, Seong-Il;Cha, Seong-Kwan;Choi, Sin-Yang
    • Microbiology and Biotechnology Letters
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    • v.35 no.2
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    • pp.173-176
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    • 2007
  • The purpose of this study was to improve the palatability of fermented red pepper soybean paste (Kochujang). Five individual models of Kochujang were prepared the following: control, glutinous rice containing 50% (A) and 100% (B) of barley, glutinous rice containing 1.5% (C) and 3.0% (D) of red rice. These Kochujangs were prepared and fermented for 60 days at 30 in a crock, and examined for changes in their physicochemical properties. There were no distinguishable change in their pH, acidity, formol-N content. L (lightness)-, a (redness)- and b (yellowness)-values were decreased rapidly until 20 days of fermentation. After 60 days, the values of L-, a- and b- of A, B Kochujang were increased than those of control, C, D Kochujang. Sensory profiles of color, flayer, taste and overall quality on the final products which fermented for 60 days showed that there were no differences in quality of each models. HMG-Co A reductase inhibitory activities were observed in 1.5% of red rice containing Kochujang.

Comparison of Biochemical Characteristics of Myofibrillar Proteins from Red Muscle and White Muscle (Red muscle과 White muscle의 근원섬유단백질의 특성의 비교)

  • Yang, Ryung;Shin, Wan-Chul;Oh, Doo-Whan;Jhin, Hong-Seung;Kim, Kee-Tae
    • Korean Journal of Food Science and Technology
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    • v.18 no.3
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    • pp.173-180
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    • 1986
  • To investigate on the biochemical characteristics of muscle fiber, myofibrils and actomyosins were prepared front red muscle and white muscle, and their ATPase activities and SDS-polyacrylamide gel electrophoretic patterns were compared. Also biochemical characteristics of bovine muscle were compared with those of chicken muscle for the detection of species characteristics. SDS-polyacrylamide gel electrophoretic analysis indicated that red muscle contained nlore 30K component of myofibril than white muscle. Differences in KCI concen-tration dependency of actomyosin ATPase activities and ATPase activity-pH cone were observed, when bovine muscle were compared with chicken muscle.

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Survey on the red internal organs gross lesions of slaughtered pigs in Jeonbuk (전북지역 도축돈 적내장 육안병변 조사)

  • Chu, Keum-Suk;Yoon, Eun-Jeong;You, Ki-Hong;Ha, Yong-Su
    • Korean Journal of Veterinary Service
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    • v.37 no.3
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    • pp.173-178
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    • 2014
  • Respiratory diseases are common in swine industry and have great economic importance. Respiratory disorders cause substantial losses to the swine industry. Losses associated with respiratory disease vary considerably between herds and seasons. In a survey was carry out to investigate the lesion of red internal organs in slaughtered pigs and provided assistant data which are useful for each farm. From november 2012 to december 2013, 1,680 pigs out of 84 farms were sampled in Jeonbuk province. Gross lesions such as swine enzootic pneumonia (SEP), pleuritis, pleuropneumonia, pericarditis, liver milk spot were examined for the pigs. Overall prevalence of SEP was 55.7%. According to season, the incidence occurred higher in fall than winter, spring, and summer. The mean SEP score was 0.91, the highest incidence occurred in fall. The prevalence of pleuropneumonia, pleuritis, pericarditis, and milk spot was 36.4%, 49.7%, 2.3%, and 8.8%, respectively. The positive rate of PRRS and PCV2 was 2.9% and 70.0% by PCR analysis.

Comparison of Physicochemical Propertres of Various Bean Starches -Cowpea, mung bean, kidney bear and red bean- (두류 전분의 이화학적 특성비교 -동부, 녹두, 강낭콩, 팥-)

  • Sohn, Kyung-Hee;Yoon, Gae-Soon;Chung, Hea-Jung;Chae, Sun-Hee
    • Korean journal of food and cookery science
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    • v.6 no.1
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    • pp.13-19
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    • 1990
  • Cowpea, mung bean, Kidney bean and red bean are simular properties. In order to elucidate the similarity among these four starches, some physicochemical properties of starches were compared. Water binding capacity of kidney bean and red bean (199%) starches are higher than mung bean and cowpea. The solubility, swlling power and optical transmittance of the four starches showed a similar pattern, but kidney bean and red bean starches had a lower swelling power than cowpea starches. Cowpea, mung bean, kidney bean and red bean starches had the blue value of 0.41, 0.47, 0.42 and 0.50, the alkali content of 8.4, 8.0, 4.13, 4.13, the amylose content of amylose of 30,000, 29,268, 52, 173 and 33, 611 and glucose unit per segment of amylopectin of 27.6, 26.8, 18.35 and 12.9 respectively. The results of X-ray diffraction studies showed A pattern for four starches.

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Korean Red Ginseng Significantly Slows CD4 T Cell Depletion over 10 Years in HIV-1 Infected Patients: Association with HLA

  • Cho, Young-Keol;Sung, Heungsup;Kim, Tai Kyu;Lim, Ji Youn;Jung, You Sun;Kang, Sang-Moo
    • Journal of Ginseng Research
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    • v.28 no.4
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    • pp.173-182
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    • 2004
  • We have shown that long-term intake of Korean red ginseng (KRG) delays disease progression in HIV-I infected patients. In the present study to investigate whether this slow progression was associated with protective human leukocyte antigen (HLA) alleles as well as with KRG-intake, we have performed clinical analysis of 31 HIV-1 infected patients who have been living for more than 10 years without any antiretroviral therapy. Average amount of KRG-intake over $130\;{\pm}16$ months was $4,797\;{\pm}4,921\;g$ and the annual decrease in CD4 T cell (AD) was $30\;{\pm}29{\mu}L$. We observed significant correlations among amount of KRG-intake, AD(r=-0.53, P < 0.01), and plasma HIV-1 RNA copy (r=-0.35, P < 0.05), along with a significant correlation between KRG-intake and HLA score AD(r=-0.49, P < 0.01), whereas there was no significant correlation between HLA score and AD or viral load. When the 31 patients were divided into 2 groups based on the amount of KRG-intake, the $AD(14/{\mu}L)$ in the 16 patients who had taken higher amounts of KRG was significantly less than that $(49/{\mu}L)$ in the 15 patients with a little or no KRG-intake (P < 0.01). These data indicate that KRG-intake sig­nificantly slows CD4 T cell depletion in HIV-1 infected patients.

Yield and Red Ginseng Quality of Super-aged Root of Panax ginseng (초고년근 고려인삼의 수량과 홍삼적성)

  • Park, Hoon;Kang, Soon-Woo;Lee, Mee-Kyoung
    • Journal of Ginseng Research
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    • v.13 no.2
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    • pp.169-173
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    • 1989
  • Seven year old ginseng was investigated for yield , the relationship between yield and percent missing plant and red ginseng quality. Yield was 2.06 kg/kan (3.3 m2) and percent missing plant was 27.1%. The highest yield plot showed 3.58 kg/kan and potential yield appeared to be 4.5 kg/kan. Yields of 1st, End and 3rd line showed significant negative linear correlation with percent missing plant. Potential yield without missing plant was in decreasing order of 1>2)3>5) 4 and negatively correlated with unit yield decrease per percent missing plant. Potential yield of 1st line was 6.56 kg/tan. Soft X-ray absorbtion characteristics was not different from that of 6 year old ginseng. Red ginseng grade and percent occurence of red ginseng quality factors were not different from those of 6 years old ginseng. The weight of red ginseng per root was much greater than that of 6 years ginseng. In view of yield and quality of fresh and red ginseng the production of red ginseng from 7 years old ginseng appears to be economically feasible.

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A Study on Red Hill Copper Deposits of the Dongjom Mine (동점광산(銅店鑛山)의 붉은등 광체(鑛體)의 성인(成因)에 관한 연구(硏究))

  • Kim, Ok Joon;Kim, Kyu Han
    • Economic and Environmental Geology
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    • v.7 no.4
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    • pp.157-173
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    • 1974
  • The Red Hill deposit of the Dongjom Copper Mine is the most promising deposit of the mine and under intensive exploration at present although there are eight more deposits of vein type. With total 2160m drilling of 9 holes completed and 400m drilling on two holes underway, the nature of the Red Hill deposit has come more clear. The copper content in the whole ore body is meager so far as the exploration done up to present indicates, but there are evidences that mineralization covers all over the granodiorite cupola at the Red Hill area. The petrological work and assay on the samples taken by the writers indicate that granodiorite rocks can be divided into fresh zone and alteration zone. Alteration zone consists of potassic and argillic zones accompanyied by silicification zone on basis of Lowell and Guilbert model Argillic zone has closely related with a mineralization in the Red Hill deposit. It has been cleared that the alteration acompanyied with the mineralization took place not only &long vertical fissures but also in the irregular lateral zone, the nature of which is unknown. Judging from the results of exploration and petrochemical study on the Red Hill deposit which is imbedded in a southern part of the granodiorite cupola, it can be concluded by the writer's opinion that the Red Hill deposit is possibly a porphyry copper deposit, because the shape of the ore body, mineral zoning and paragenesis and wall rock alteration resemble to those of typical porphyry copper deposits. It is the writers' opinion that more exploration work is required so as to evaluate the deposit.

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Water Transport during the Single-pass Perfusion Experiments : Effects of Some Perfusates and Their Osmolality (일회통과 관류실험시 물의 수송 : 관류액의 종류와 삼투압의 영향)

  • 이정화;이현주;용철순;오두만
    • YAKHAK HOEJI
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    • v.39 no.4
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    • pp.411-416
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    • 1995
  • The single-pass perfusion experiments were performed in anesthetized rats to investigate the effects of perfusates and their osmolality on the water transport and to determine the correlation between the extent of water transport and the volume change of perfusate. Phenol red was used as a nonabsorbable marker. In normal rats, when perfused at a flow rate of 0.5 ml/min, 2-(N-rnorpholino) ethanesulfonic acid (MES) and S$\phi$rensen's phosphate buffers showed minimal net water transport as 0.125 and 0.173 %/cm of intestinal length, respectively. Hypotonic perfusate of 200 mOsm/kg of water and hypertonic perfusate of 400 mOsm/kg of water generated significant water transport compared with isotonic perfusate of 300 mOsm/kg of water. There was a linear correlation between the extent of water transport and the volume change of perfusate, suggesting that the volume change can be used as a measure of water transport.

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Study on the Nonlinear Interaction of Laser with Plasma -Detection of Second Harmonic Light and Brillouin Scattering Light by Means of Spectroscopic Technique- (레이저와 프라즈마와의 비선형상오작용에 관한 연구 -분광법에 의한 제 2고주파와 Brillouin 산람광의 검출-)

  • Kang, Hyung-Boo
    • The Transactions of the Korean Institute of Electrical Engineers
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    • v.33 no.5
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    • pp.173-180
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    • 1984
  • The spectra of scattering light fromlaser-produced plasma near its fundamental and second harmonic wavelength were observed respectively by means of spectroscopic technique. The experimental results and the generation mechanism of nonlinear effects such as the second garmonics and the brillouin scattering were analysed theoretically. The spectra of reflected laser light became wider than that of incident laser light. And the peak of spectrum of reflected light shifted to red-side from that of incident light. The second harmonic light is generated from the nonlinear interaction of the incident laser light and the electron plasma wave excited in resonance region by the oblique incidence of laser light to the plasma. The Brillouin backscattering from laser-produced plasmas of hydrogen and deuterium has shown an isotope effect in the red-side region of the generated second harmonic light. This isotope shift is explained by the parametric instability at the cutoff (resonance) region using frequency-and phase-matching conditions of the waves.

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