• Title/Summary/Keyword: rearrangement

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Synthesis of Hydroxycyclopentane as a Synthetic Intermediate for Carbaprostacyclin (카바프로스타싸이클린의 중간체로 이용가능한 히드록시싸이클로펜탄의 합성)

  • 서영거;구본암;정재경;조윤상;나운용
    • YAKHAK HOEJI
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    • v.37 no.3
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    • pp.290-294
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    • 1993

  • An efficient synthetic route to the trisubstituted cyclopentane as an useful synthetic intrermediate for carbaprostacyclin is described. Ireland Claisen rearrangement of a hydroxylactone has been employed as a key reaction.

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Synthesis of 1, 1-Diheteroaryl Ethylenes by a Tandem Appel's Dehydration/Thermal Rearrangement Methodology

  • 이기정;허 열;전종갑
    • Bulletin of the Korean Chemical Society
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    • v.20 no.3
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    • pp.341-344
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    • 1999

  • The hydrazones of 2-acetylfuran, 2-acetylthiophene, and 2-acetylpyrrole, were allowed to react with S-methylthioacetimidate hydroiodide (8) to give azinoureas 10, and the reaction of 10 with Appel's dehydration conditions (triphenylphosphine/carbon tetrachloride/triethylamine) led to the corresponding azinocarbodiimides 11, which underwent thermal rearrangement under the reaction conditions to give 1,1-diheteroaryl ethylenes 13.

  • https://doi.org/10.5012/bkcs.1999.20.3.341 인용 PDF