Synthesis of Hydroxycyclopentane as a Synthetic Intermediate for Carbaprostacyclin

카바프로스타싸이클린의 중간체로 이용가능한 히드록시싸이클로펜탄의 합성

An efficient synthetic route to the trisubstituted cyclopentane as an useful synthetic intrermediate for carbaprostacyclin is described. Ireland Claisen rearrangement of a hydroxylactone has been employed as a key reaction.