• Journal of Internet Computing and Services
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• v.9 no.3
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• pp.141-158
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• 2008

In this paper, we developed the GML Map Server which visualized the map based on GML as international standard for exchanging the common format map and for interoperability of GIS information. And also, it should transmit effectively GML map into the mobile device by using dynamic map partition and caching. It manages a partition based on the visualization area of a mobile device in order to visualize the map to a mobile device in real time, and transmits the partition area by serializing it for the benefit of transmission. Also, the received partition area is compounded in a mobile device and is visualized by being partitioned again as four visible areas based on the display of a mobile device. Then, the area is managed by applying a caching algorithm in consideration of repetitiveness for a received map for the efficient operation of resources. Also, in order to prevent the delay in transmission time as regards the instance density area of the map, an adaptive map partition mechanism is proposed for maintaining the regularity of transmission time. GML Map Server can trace the position of mobile device with WIPI environment in this paper. The field emulator can be created mobile devices and mobile devices be moved and traced it's position instead of real-world. And we developed POIM(POI Management) for management hierarchically POI information and for the efficiency POI search by using the individual tagging technology with visual interface.

• The KIPS Transactions:PartD
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• v.12D no.2 s.98
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• pp.259-266
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• 2005

Recently data centric routing or application dependent routing protocols are emerged in mobile ad hoc networks. In this paper, we propose a routing method for query processing in MANET(Mobile Ad hoc NETwork) environment, called road-based query routing, with consideration on real time traffic information of large number of vehicles. In particular, we focus on the method that process arrival time dependent shortest path query in MANET without a central server on the road networks. The main idea of our approach lies in a routing message that includes query predicates based on the road connectivity and on data gathering method in real time from vehicles on the road by ad-hoc network. We unify route discovery phase and data delivery(query processing) phase in our mechanism and reduce unnecessary flooding messages by pruning mobile nodes which are not on the same or neighboring road segments. In order to evaluate the performances of the proposed method, we established a model of road networks and mobile nodes which travel along the roads. The measurement factor is the number of nodes to whom route request is propagated according to each pruning strategy. Simulation result shows that road information is a dominant factor to reduce the number of messages.

• Clinical and Experimental Pediatrics
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• v.51 no.2
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• pp.170-180
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• 2008

Purpose : Some antibiotics were known to exert neuroprotective effects in the animal model of hypoxic-ischemic (H-I) brain injury, but the mechanism is still unclear. A recent study reported that geneticin (G418), an aminoglycoside antibiotic, increased survival of human breast cancer cells by suppressing apoptosis. We investigated the neuroprotective effects of systemically administrated geneticin via anti-apoptosis following the H-I brain injury Methods : Seven-day-old Sprague-Dawley rat pups were subjected to unilateral (left) common carotid artery occlusion followed by 2.5 hours of hypoxic exposure and the cortical cell culture of rat brain was done under a hypoxic incubator. Apoptosis was measured in the injured hemispheres 7 days after H-I insult and in the injured cells from hypoxic chamber using morphologic analysis by Terminal dUTP Nick-end Labeling(TUNEL) assay and immunohistochemistry for caspase-3, and cytologic analysis by western blot and real time PCR for bax, bcl-2, and caspase-3. Results : The gross appearance and hematoxylin and eosin stain revealed increased brain volume in the geneticin-treated animal model of perinatal H-I brain injury. The TUNEL assay revealed decreased apoptotic cells after administration of geneticin in the cell culture model of anoxia. Immunohistochemistry showed decreased caspase-3 expression in geneticin-treated cortical cell culture. Western blot and real-time PCR showed decreased caspase-3 expression and decreased ratio of Bax/Bcl-2 expression in geneticin-treated animal model. Conclusion : Geneticin appears to exert a neuroprotective effect against perinatal H-I brain injury at least via anti-apoptosis. However, more experiments are needed in order to demonstrate the usefulness of geneticin as a preventive and rescue treatment for H-I brain injuries of neonatal brain.

• Journal of Energy Engineering
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• v.13 no.1
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• pp.60-67
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• 2004

The recent movement to deregulated and competitive electricity market reacquires new concepts against existing central dispatch in the system operation and pinning. As power systems tend to be operated more closely to their ultimate ratings, the role of SCOPF (Security Constrained Optimal Power flow) is changed and the importance for real-time security inhancement will be more increased i]1 the new and com partitive electricity market. This paper deals with the application of the SCOPF which makes possible the On-Line application. The security margin of power system truly is changed according to the conditions or configuration of power systems, therefore, the sensitivity factor reiated to the security is recalculated and the application should be updated in accordance with the state of power system. The goal of this paper is to obtain proper security through the effluent usage of the sensitivity and to apply this a1gorithm to system operation. The proposed mechanism has been tested on a sample system and the results show more secure conditions against critical contingencies.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.24 no.6B
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• pp.1113-1122
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• 1999

In this paper, we propose MSS(Multicast Synchronization Server) and QCS(QoS Conversion Server) models that can support IP multicast and QoS(Quality of Service) over the ATM network more efficiently. In the MSS model, it is possible to establish shortcut VCs(Virtual Circuits) among all hosts in the ATM network and to transfer multicast data at high speed. Also the MSS model is more scalable, because the number of inter-cluster VCs needed in the MSS model is less than that of EARTH. In the QCS model, ATM switch is modified to support one QoS service and best effort service through the one point-to-multipoint VC at the same time so required network resources are reduced, and dedicated server is used for QoS conversion to accept heterogeneous receivers more efficiently. In this Paper, the proposed MSS model and QCS model have solved both efficiency problem and scalability problem. It is proved through the comparison of the VCs required in each model.

• Journal of Microbiology and Biotechnology
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• v.20 no.2
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• pp.271-280
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• 2010

Vibrio alginolyticus, a Gram-negative marine bacterium, is one of the causative agents of fish vibriosis. Its virulence factors and pathogenesis mechanism are barely known, except for some extracellular products (ECPs) that are known to be regulated by quorum sensing system. Therefore, the present study used a microarray to analyze the transcription profiles of the wild-type V. alginolyticus and a deletion mutant of luxO, the pivotal regulator in Vibrio quorum sensing systems, which resulted in the identification of a putative virulence factor, MviN. Quantitative real-time reverse transcription PCR confirmed that the transcription of mviN was upregulated in the luxO mutant when compared with wild-type, and down regulated in a luxO-con complemented strain. Furthermore, Western blotting indicated that MviN was greatly induced during the late-exponential and stationary phases of growth, indicating that the expression of MviN was cell-density dependent and quorum sensing regulated in V. alginolyticus. Meanwhile, the mviN null mutant displayed a much slower growth rate than the wild type, signifying the essential role of MviN in V. alginolyticus. Western blotting also revealed that MviN was present as an extracellular protein in V. alginolyticus. When epithelioma papulosum cyprini (EPC) cells were treated with the ECPs of the mviN mutant, no cytotoxicity was observed, whereas EPC cells treated with the wild type exhibited pathological changes, which increased with the ECPs concentration and treatment time. Therefore, the results demonstrated that MviN is a LuxO-regulated ECPs component and involved in the pathogenicity of V. alginolyticus.

• Journal of the Korea Society of Computer and Information
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• v.19 no.7
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• pp.103-111
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• 2014

This paper proposes a modified algorithm that improves on Dijkstra's algorithm by applying it to purely two-way traffic paths, given that a road where bi-directional traffic is made possible shall be considered as an undirected graph. Dijkstra's algorithm is the most generally utilized form of shortest-path search mechanism in GPS navigation system. However, it requires a large amount of memory for execution for it selects the shortest path by calculating distance between the starting node and every other node in a given directed graph. Dijkstra's algorithm, therefore, may occasionally fail to provide real-time information on the shortest path. To rectify the aforementioned shortcomings of Dijkstra's algorithm, the proposed algorithm creates conditions favorable to the undirected graph. It firstly selects the shortest path from all path vertices except for the starting and destination vertices. It later chooses all vertex-outgoing edges that coincide with the shortest path setting edges so as to simultaneously explore various vertices. When tested on 9 different undirected graphs, the proposed algorithm has not only successfully found the shortest path in all, but did so by reducing the time by 60% and requiring less memory.

• The KIPS Transactions:PartB
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• v.11B no.3
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• pp.353-360
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• 2004

The study on scene change detection in the compressed MPEG videos has been done by various approaches. However, most of these approacher accomplished scene change detection by carrying out decoding processes and then by comparing pixels with pixels. This approach it not suitable for real time applications owing to much computing time of decoding processes. Recently, the study on scene change detection algorithms using only information of compressed domain is becoming Increasingly important. In this paper, we propose a sequential access method as an efficient scene change detection algorithm in the compressed domain. According to the type of pictures in the compressed MPEG video streams (divided in I-blocks and each I-block into P-blocks), the proposed algorithm provides effective scene change detection by applying sequential access and block by block mechanism. The proposed sequential access method provides fast and accurate detection operation by reducing checking procedures of unnecessary pictures due to molt of operations in compressed domain and checking by block units. Also, this approach uses optimal algorithm to provide fast and accurate detection operation.

• Advances in aircraft and spacecraft science
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• v.2 no.2
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• pp.125-168
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• 2015

Dynamic aeroelastic behavior of structurally nonlinear Joined Wings is presented. Three configurations, two characterized by a different location of the joint and one presenting a direct connection between the two wings (SensorCraft-like layout) are investigated. The snap-divergence is studied from a dynamic perspective in order to assess the real response of the configuration. The investigations also focus on the flutter occurrence (critical state) and postcritical phenomena. Limit Cycle Oscillations (LCOs) are observed, possibly followed by a loss of periodicity of the solution as speed is further increased. In some cases, it is also possible to ascertain the presence of period doubling (flip-) bifurcations. Differences between flutter (Hopf's bifurcation) speed evaluated with linear and nonlinear analyses are discussed in depth in order to understand if a linear (and thus computationally less intense) representation provides an acceptable estimate of the instability properties. Both frequency- and time-domain approaches are compared. Moreover, aerodynamic solvers based on the potential flow are critically examined. In particular, it is assessed in what measure more sophisticated aerodynamic and interface models impact the aeroelastic predictions. When the use of the tools gives different results, a physical interpretation of the leading mechanism generating the mismatch is provided. In particular, for PrandtlPlane-like configurations the aeroelastic response is very sensitive to the wake's shape. As a consequence, it is suggested that a more sophisticate modeling of the wake positively impacts the reliability of aerodynamic and aeroelastic analysis. For SensorCraft-like configurations some LCOs are characterized by a non-synchronous motion of the inner and outer portion of the lower wing: the wing's tip exhibits a small oscillation during the descending or ascending phase, whereas the mid-span station describes a sinusoidal-like trajectory in the time-domain.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.18
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• pp.7527-7532
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• 2014

Saussurea involucrata is a Mongolian medicinal plant well known for its effects in promoting blood circulation, and anti-inflammation and analgesic functions. Earlier studies reported that Saussurea involucrata has anticancer activity. The purpose of this study was to confirm the anticancer activity of an ethanol extract of Saussurea involucrata against hepatic cancer and elucidate its mechanisms of action. Hepatocellular carcinoma cells were tested in vitro for cytotoxicity, AO/EB staining for apoptotic cells, apoptotic DNA fragmentation and cell cycle distribution in response to Saussurea involucrata extract (SIE). The mRNA expression of caspase-3,-9 and Cdk2 and protein expression of caspase-3,-9, PARP, XIAP, Cdk2 and p21 were analyzed through real time PCR and Western blotting. Treatment with SIE inhibited HepG2 cell proliferation dose- and time-dependently, but SIE only exerted a modest cytotoxic effect on a viability of Chang human liver cells. Cells exposed to SIE showed typical hallmarks of apoptotic cell death. Cell cycle analysis revealed that SIE caused G1-phase arrest in HepG2 cells. In conclusion, Saussurea involucrata ethanol extract has potential cytotoxic and apoptotic effects on human hepatocellular carcinoma cells. Its mechanism of action might be associated with the inhibition of DNA synthesis, cell cycle (G1) arrest and apoptosis induction through up-regulation of the protein expressions of caspase-3,-9 a nd p21, degradation of PARP and down-regulation of the protein expression of Cdk2 and XIAP.