• Molecular & Cellular Toxicology
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• v.5 no.2
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• pp.147-152
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• 2009

This study was conducted to evaluate the inflammatory mechanisms of LPS-stimulated BV-2 microglial cells. The inflammation mechanism was evaluated in BV-2 cells with or without LPS treated using the Affymetrix microarray analysis system. The microarray analysis revealed that B cell receptor signaling pathway, cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, MAPK signaling pathway, Neuro-active ligand-receptor interaction, TLR signaling path-way, and T cell receptor signaling pathway-related genes were up-regulated in LPS stimulated BV-2 cells. Selected genes were validated using real time RTPCR. These results can help an effective therapeutic approach to alleviating the progression of neuro-in-flammatory diseases.

• Molecules and Cells
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• v.26 no.6
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• pp.517-529
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• 2008

Porosomes are supramolecular, lipoprotein structures at the cell plasma membrane, where membrane-bound secretory vesicles transiently dock and fuse to release inravesicular contents to the outside during cell secretion. The mouth of the porosome opening to the outside, range in size from 150 nm in diameter in acinar cells of the exocrine pancreas, to 12 nm in neurons, which dilates during cell secretion, returning to its resting size following completion of the process. In the past decade, the composition of the porosome, its structure and dynamics at nm resolution and in real time, and its functional reconstitution into artificial lipid membrane, have all been elucidated. In this mini review, the discovery of the porosome, its structure, function, isolation, chemistry, and reconstitution into lipid membrane, the molecular mechanism of secretory vesicle swelling and fusion at the base of porosomes, and how this new information provides a paradigm shift in our understanding of cell secretion, is discussed.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 1997.04a
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• pp.873-877
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• 1997

This paper presents experimental results to know the charcteristics of machined surface due to cutter runout. Cutter runout is a common but undesirable phenomenon in multi-tooth machining such as end-milling process because it introduces variable chip loading to insert which results in a accelerated tool wear, amplification of force variation and hence enargement vibration amplitude. To develop in-proess cutter runout compensation system, set-up the micro-positoning mechanism which is based on piezoelectric translator embeded in the work holder to manipulate the depth of cut in real-time. And feasibility test of system was done under the various experimental cutting conditions. This results provide lots of information to build-up the precision machining technology.

• International Journal of Internet, Broadcasting and Communication
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• v.10 no.1
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• pp.16-22
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• 2018

This paper presents a solution for personal profiling system based on user-oriented tracking. Here, we introduce a new way to identify and track humans by using two types of cameras: dome and face camera. Dome camera has a wide view angle so that it is suitable for tracking human movement in large area. However, it is difficult to identify a person only by using dome camera because it only sees the target from above. Thus, face camera is employed to obtain facial information for identifying a person. In addition, we also propose a new mechanism to locate human on targeted location by using grid-cell system. These result in a system which has the capability of maintaining human identity and tracking human activity (movement) effectively.

• International Journal of Control, Automation, and Systems
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• v.1 no.4
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• pp.444-452
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• 2003

An integration system with multi-measurement sets can be realized via combined application of a centralized and federated Kalman filter. It is difficult for the centralized Kalman filter to remove a failed sensor in comparison with the federated Kalman filter. All varieties of Kalman filters monitor innovation sequence (residual) for detection and isolation of a failed sensor. The innovation sequence, which is selected as an indicator of real time estimation error plays an important role in adaptive mechanism design. In this study, the centralized Kalman filter with adaptive measurement fusion is introduced by means of innovation sequence. The objectives of adaptive measurement fusion are automatic isolation and recovery of some sensor failures as well as inherent monitoring capability. The proposed adaptive filter is applied to the GPS/SDINS integration system with an additional sensor. Simulation studies attest that the proposed adaptive scheme is effective for isolation and recovery of immediate sensor failures.

• Journal of the Korean Institute of Telematics and Electronics B
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• v.31B no.10
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• pp.1-10
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• 1994

In most application programs, loops usually contain most of the computation in a program and are the most improtant source of parallelism. When loops are executed on multiprocessors, the cross iteration data dependences need to be enforced by synchronization between processors. In this paper, we propose a new synchronization scheme(Free/Hold) for reducing overgeads occured by synchronization variables in data oriented scheme and delay of time occured by synchronization instruction in statement oriented scheme. The Free/Hold mechanism enforces the correct execution order by inserting synchronization instruction between each instance with data dependence relationship using the RD(Real dependence Distance). We also present an algorithm for removing unnecessary dependences in one-to-many dependences.

• Journal of Magnetics
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• v.19 no.3
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• pp.237-240
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• 2014

For heat-assisted magnetic recording, magnetization reversal probabilities of nano-Pt/MnSb multilayer film with perpendicular magnetic anisotropy under thermal pulse activation were investigated numerically by solving the Landau-Lifshift Gilbert Equation. Magnetic parameters of nano-Pt/MnSb multilayer were used with anisotropy energy of $3{\times}10^5$ erg/cc and saturation magnetization of 2100 G, which offer more than 10 y data stability at room temperature. Scheme of driven magnetic field and thermal pulse on writing mechanism was designed closely to real experiment. This study found that the chosen material is potential to be used as a high density magnetic storage that requires low writing field less than two-hundreds Oersted through definite heating and cooling interval. The possibility of writing data with a zero driven magnetic field also became an important result. Further study is recommended on the thickness of media and thermal pulse design as the essential parameters of the reversal magnetization.

• Proceedings of the IEEK Conference
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• 2000.06e
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• pp.159-162
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• 2000

This paper addresses the design and implementation problem of the mobile robot with the synchronous driving mechanism that consists of modular control systems based on the Universal Serial Bus (USB). Recently, the USB have attracted the hardware developers'interests due to its low cost, compatibility, and extenability. In particular, the USB enables us to organize the whole system in the modular manner very easily, and this property plays a very important role in shortening the developing time in implementing the target system, for example, the mobile robot system. In this paper, we implement the USB motion controller and the USB ultrasonic sensor system and verified the validity and the effectiveness of the proposed system through the real experiments including the mobile robot navigation and the environment recognition.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.41 no.8
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• pp.27-33
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• 2004

A new multicast scheme for mobile nodes is proposed to support real-time communication in a more efficient way. In the proposed multicast scheme, the Xcast (a very flexible data plane mechanism) is integrated with the SIP (a very flexible control plane protocol) to support multicast for mobile nodes. The simulation results verify that the proposed scheme reduces unnecessary network traffic and achieves low latency of packets in the network.

• Proceedings of the Korean Society of Machine Tool Engineers Conference
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• 2000.04a
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• pp.679-684
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• 2000

This paper presents the development of system and program for a Parallel-Typed CNC Machine. The system consists of parallel manipulator, PC (Personal Computer), DMC (DSP Motion Controller), and machining tools. In order to control the manipulator, the program, which is implemented in "c/c++" language, involves inverse/direct kinematics, velocity mapping, Jacobian and etc. A controller computes the kinematic formulation in real-time and generates and motion by the DMC. A monitor, which has access to program and sensory information, displays the status of manipulator.nipulator.