• Journal of Life Science
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• v.17 no.7 s.87
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• pp.996-1001
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• 2007

To investigate whether sulindac, sulindac sulfone, and sulindac sulfide could affect cancer cell viabilities, human colorectal HCTl16 cells were treated with 10 ${\mu}M$ of each NSAID. Among treated NSAms, sulindac sulfide dramatically decreased the cell viabilities detected by MTS and the cytotoxic effect showed dose-dependent manner. To understand the molecular mechanism of cell death in response to sulindac sulfide treatment, we performed oligo DNA microarray analysis. We found that 23 genes were up-regulated more than 2 folds, whereas 33 genes were down-regulated more than 2 folds by treatment of 10 ${\mu}M$ sulindac sulfide. Among the up-regulated genes, we selected 3 genes (NAG-1, DDIT3, PCK2) and performed RT-PCR and quantitative real-time PCR to cofirm microarray data. The results of RT-PCR and real-time PCR were highly accorded with those of microarray experiment. As NAG-1 is well-known gene as tumor suppressor, we detected changes of NAG-1 expression by 10 ${\mu}M$ of sulindac, sulindac sulfone, and sulindac sulfide. The results of RT-PCR and quantitacve real-time PCR indicated that sulindac sulfide was the strongest inducer of NAG-1 among treated NSAIDS. This result implies that induction of NAG-1 by sulindac sulfide plays important role in cell death of colorectal cancer. Overall, we speculate that these results may be helpful in understanding the molecular mechanism of the cancer chemoprevention by sulindac sulfide in human colorectal cancer.

• 제어로봇시스템학회:학술대회논문집
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• 1987.10b
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• pp.674-679
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• 1987

Process failures can occur at any time during operation, so a continuous effort of fault detection, diagsis, and correction is required. Expert system paridigm has been regarded as a promising approach to real time process supervisory control especially to fault diagnosis. The most important aspects of fault diagnostic expert systems(FDES) are the problem-solving inference strategy and knowledge organizations. The necessity of FDES, the nature of diagnostic knowledge, the representation of knowledge, and the inference mechanism of FDES, et al. are described, which are announced by previous researchers. And the existing FDES are categorized and critically reviewed in this work.

• Journal of Biosystems Engineering
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• v.43 no.4
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• pp.273-284
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• 2018

Purpose: Conventional headland turning typically requires repeated forward and backward movements to move the farming equipment to the next row. This research focuses on developing an upland agricultural robot with an optimized headland turning mechanism that enables a $180^{\circ}$ turning positioning to the next row in one steering motion designed for a two-wheel steering, four-wheel drive agricultural robot named the HADA-bot. The proposed steering mechanism allows for faster turnings at each headland compared to those of the conventional steering system. Methods: The HADA-bot was designed with 1.7-m wide wheel tracks to travel along the furrows of a garlic bed, and a look-ahead path following algorithm was applied using a real-time kinematic global positioning system signal. Pivot turning tests focused primarily on accuracy regarding the turning radius for the next path matching, saving headland turning time, area, and effort. Results: Several test cases were performed by evaluating right and left turns on two different surfaces: concrete and soil, at three speeds: 1, 2, and 3 km/h. From the left and right side pivot turning results, the percentage of lateral deviation is within the acceptable range of 10% even on the soil surface. This U-turn scheme reduces 67% and 54% of the headland turning time, and 36% and 32% of the required headland area compared to a 50 hp tractor (ISEKI, TA5240, Ehime, Japan) and a riding-type cultivator (CFM-1200, Asia Technology, Deagu, Rep. Korea), respectively. Conclusion: The pivot turning trajectory on both soil and concrete surfaces achieved similar results within the typical operating speed range. Overall, these results prove that the pivot turning mechanism is suitable for improving conventional headland turning by reducing both turning radius and turning time.

• Proceedings of the KIEE Conference
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• 2004.11c
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• pp.657-659
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• 2004

CAN is a serial communication bus for real-time controls and automations in distributed control systems. In distributed control systems, occasionally a sensor module and a controller are not in the same node and physically separated. In order for the signal from a sensor node to reach the controller node, the signal must travel through network. CAN has a certain capabilities to deal with real-time data. However, when many nodes on the networks try to send data on the same network, the arbitration mechanism to solve the data collision problem is necessary. This situation causes the time delay which has detrimental effects on the performance of the control systems. This paper proposes a method to solve the problem due to the time delay in distributed control system using CAN. Time delay is approximated to an element with a rational transfer function using Pade approximation and Mu~synthesis method is applied. Since time delay in the network is not constant, the time delay element is considered to be an uncertainty block with a bound. The proposed method is applied to the experimental system with CAN and proved to be effective.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2006.05a
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• pp.295-296
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• 2006

We developed wire frame drive unit based on SMA for the 3D Shape display. Our basic concept is wire frame combination connected with a chain form which can create various shapes and it compared with pin array mechanism which is not able to display mushroom shape. It imitates antagonist mechanism of human musculoskeletal system. we create similar motion using repair-relaxation mechanism and locking mechanism by SMA. Therefore, in this paper, we propose SMA control solution for actuating repair-relaxation mechanism and locking mechanism. In our control system. we use optical sensor and quantitative angle between wire frames for closed loop control. And we supply amplified current for SMA by circuit composed of transistor and apply PWM signal to circuit for efficient control. So, wire frame drive unit enable diversity angle control based on sensor data. And then combination of wire frame drive units will create various objects.

• Journal of Internet Computing and Services
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• v.7 no.2
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• pp.137-149
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• 2006

In this paper, we suggest a message-based communication protocol and a dynamic role assignment mechanism for efficient cooperation and teamwork of agents in computer game environments. This role assignment mechanism is a new one different from both existing static and dynamic mechanisms, in which all decisions related with role assignment are made at once in design phase or execution phase. According to our mechanism, all possible role sets are determined in design phase. Detail decisions regarding which agent takes what role, however, are made in execution phase. This mechanism for role assignment can minimize the negotiation effort in execution phase. Therefore, this mechanism is quite effective especially in real-time multiagent environments. Through experiments, we show the superiority of the new dynamic role assignment mechanism.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.10 no.1
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• pp.191-196
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• 2006

This paper presents the moving object tracking method using vision system. In order to track object in real time, the image of moving object have to be located the origin of the image coordinate axes. Accordingly, Fuzzy Control System is investigated for tracking the moving object, which control the camera module with Pan/Tilt mechanism. Hereafter, so the this system is applied to mobile robot, we design and implement image processing board for vision system. Also fuzzy controller is implemented to the StrongArm board. Finally, the proposed fuzzy controller is useful for the real-time moving object tracking system by experiment.

• IEMEK Journal of Embedded Systems and Applications
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• v.10 no.4
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• pp.213-219
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• 2015

Real-time energy monitoring systems is a demand-response system which is reported to be effective in saving energy up to 12%. Real-time energy monitoring system is commonly composed of smart-plugs which sense how much electrical power is consumed and IHD(In-Home Display device) which displays power consumption patterns. Even though the monitoring system is effective, users should themselves match which smart plus is connected to which appliance. In order to make the matching work to be automatic, the monitoring system need to have appliance identification algorithm, and some works have made under the name of NILM(Non-Intrusive Load Monitoring). This paper proposed an algorithm which utilizes multiple classifiers to improve accuracy of appliance identification. The algorithm proposes to understand each classifiers performance, that is, when a classifier make a result how much the result is reliable, and utilize it in choosing the final result among result candidates from many classifiers. By using the proposed algorithm this paper make 4.5% of improved accuracy with respect to using single best classifier, and 2.9% of improved accuracy with respect to other method using multiple classifiers, so called CDM(Commitee Decision Mechanism) method.

• The Transactions of the Korea Information Processing Society
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• v.4 no.1
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• pp.288-297
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• 1997

Real-time video multicast using a single computer system is a difficult task because capturing, compressing and delivering video causes a long delay in internetworking environments. This paper describes an implementation of the real time video multicasting server which processes video capture, compression and multicasting in parallel. This paper also presents a flow control mechanism to solve a problem caused by difference between the three tasks.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.9 no.1
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• pp.71-84
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• 1999

The most of intrusion detection methods do not detect intrusion when it happens. To solve the problem, we are studying a real-time intrusion detection. Because a previous intrusion detection system(IDS) is running on the host level, it difficult to port and to extend to other system on the network level that distributed environment. Also IDS provides the confidentiality of messages when it sends each other. This paper proposes a model of real-time intrusion detection using agents. It applies to distributed environment using an extensibility and communication mechanism among agents, supports a portability, an extensibility and a confidentiality of IDS.