• Title/Summary/Keyword: real options

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Development and Applications of A Paternity and Kinship Analysis System Based on DNA Data (유전자 분석 자료에 의한 친자 및 혈연관계 분석시스템 개발 및 활용)

  • Koo, Kyo-Chan;Kim, Sun-Uk
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.10
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    • pp.6715-6721
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    • 2015
  • Recently, DNA data of missing person, killed person, and missing child continue to increase but most of statistical calculation for paternity confirmation is being done through manual methods or Excel. Therefore, we need development of a software which is able to facilitate both systematic management and effective analysis of Short Tandem Repeat (STR) derived from DNA data. Without extensive testing, through a twenty-month study was developed a web-based system which performs paternity analysis and kinship analysis easily based on the various options. The former uses an existing algorithm for paternity index and the latter does Identity by descent (IBD) formula. Due to our system validated over real datasets in terms of likelihood ratio and probability of paternity, it ensures increased reliability as well as effective management and analysis of DNA data in mass disaster. In addition, it includes advanced features such as an integrated environment, user-centered interface, process automation and so on.

Community ambulation in patients with chronic post-stroke hemiparesis : Comparison of walking variables in five different community situations (만성 뇌졸중 환자의 지역사회 보행: 다섯 보행 조건의 비교)

  • Hwang, Eun-Ok;Oh, Duck-Won;Kim, Suhn-Yeop
    • Journal of Korean Physical Therapy Science
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    • v.16 no.1
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    • pp.31-39
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    • 2009
  • Background: Community ambulation has been recently recognized as one of the most essential factors of activities of daily living in patients with post-stroke hemiparesis. This study aimed to compare walking velocity and step number in 5 community situations in patients with post-stroke hemiparesis. Methods: Ten chronic stroke patients volunteered for this study. The main variables analyzed were walking speed and step number, and these were measured in 5 different community situations: a physical therapy room, a parking lot, a bank, a crosswalk, and a hospital lobby. The measurements obtained for walking in the physical therapy room were measured using a 10m walk test and were used as baseline data for comparison with each option. The ambulation distance was set at 300m for the parking lot and the bank and 150m for the crosswalk and hospital lobby. For data analysis, walking speed and step number were standardized with the distance options of each ambulation. Results: Compared to the walking speed in the physical therapy room, those in the other situations, except for the parking lot, were significantly different (p<.05). Moreover, there were significant differences in the speeds between the bank and the parking lot and between the parking lot and the crosswalk (p<.05). Compared to the step number in the physical therapy room, those in all situations except for the crosswalk were significantly different (p<.05). Further, there was a significant difference in the step number between the bank and the crosswalk (p<.05). Conclusion: The walking ability of patients with hemiparesis in real environments within a community could be different from that in a physical therapy room. Therefore, the evaluation of walking should be performed in a variety of community situations.

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Development of TASS Code for Non-LOCA Safety Analysis Licensing Application (Non-LOCA 인허가 해석용 TASS 코드의 개발)

  • Yoon, Han-Young;Auh, Geun-Sun;Kim, Hee-Cheol;Kim, Joon-Sung;Park, Jae-Don
    • Nuclear Engineering and Technology
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    • v.27 no.1
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    • pp.53-66
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    • 1995
  • Since the current licensed system codes for Non-LOCA safety analysis are applicable only for a specific type PWR, it is necessary to develope a new system analysis code applicable for all apes of PWRs. As a R&D program, KAERI is developing TASS code as an interactive and faster-than-real-time code for the NSSS transient simulation of both CE and Westinghouse plane. It is flexible tool for PWR analysis which gives the user complete control over the simulation through convenient input and output options. In this paper the code applicability to Westinghouse ape plants was verified by comparing the TASS prediction to plant data of loss of AC power and loss of load transients, and comparing to the prediction of RELAP5/MOD3 for feedline break, locked rotor, steam generator tube rupture and steam line break accidents.

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Review of Clinical Research of Korean Medicine on Postpartum Pelvic Organ Prolapse (산후 골반장기탈출증에 대한 한의학적 임상 연구 동향)

  • Park, Nam-Gyeong;Hwang, Young-Sik;Kim, Gyu-Tae;Park, Seung-Hyeok;Lee, Jin-Moo;Lee, Chang-Hoon;Jang, Jun-Bock;Hwang, Deok-Sang
    • The Journal of Korean Obstetrics and Gynecology
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    • v.33 no.4
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    • pp.93-112
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    • 2020
  • Objectives: The purpose of this study is to review the clinical research trends of postpartum pelvic organ prolapse and to recognize the efficacy of Korean medicine intervention. Methods: Based on seven domestic and foreign databases, including Research Information Sharing Service (RISS), Oriental Medicine Advanced Searching Integrated System (OASIS), Journal of Korean Obstetric and Gynecology, Cochrane Library Central, Pubmed, China National Knowledge Infrastructure (CNKI) and WangFang Med Online, we analyzed the clinical trials using Korean medicine intervention, which included acupuncture and herbal medicine. Data retrieval was carried out on May 18 to 20, 2020, and a total of 13 papers were included. Results: All papers were published in China and it contains nine randomized controlled trials, three clinical trials, and one case. The most frequently used intervention was herbal medicine, and Bupleuri Radix, Cimicifugae Rhizoma were used. The treatment group treated by Korean medicine intervention was more effective than the control group. Also, there were no significant side effects of Korean medicine. Conclusion: This study shows that Korean medicine can be effective and safe medical alternatives or options for pelvic organ prolapse patients. However, to laying the foundation of clinical guidelines and applying it to the real-world clinical scene, further follow-up research is needed.

A Spatial Index Compression Scheme Using Semi-Approximation (준근사를 이용한 공간 인덱스 압축 기법)

  • Kim, Jong-Wan
    • Journal of the Korea Society of Computer and Information
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    • v.11 no.1 s.39
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    • pp.97-105
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    • 2006
  • Over the last several years, studies on spatial index have increased in proportion to the increase in the spatial data. Most of these studies, however were on the indices based on R-tree by adding or changing some options, and there are a few studies on how to increase the search performance of the spatial data by compressing an MBR. This study was conducted in order to propose a new MBR compression scheme, SA(Semi-Approximation). The basic idea of this paper is the compression of MBRs in a spatial index. Since SA decreases the keys of MBRs, the enlargements of QMBR in half and increases the utilization of nodes, the SA heightens the overall search performance. The study analyzes mathematically the number of node accesses in a 2D space and evaluates the performance of the SA using the real data on location information. The results show that the proposed scheme has increased performance, higher than that of the pre-established schemes on compression of MBR.

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Conceptual Design Trade Offs between Solid and Liquid Propulsion for Optimal Stage Configuration of Satellite Launch Vehicle

  • Qasim, Zeeshan;Dong, Yunfeng
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2008.03a
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    • pp.283-292
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    • 2008
  • The foremost criterion in the design of a Satellite Launch Vehicle(SLV) is its performance capability to boost the designated payload to the desired mission orbit; it starts from focusing on the SLV configuration to achieve the velocity requirements($}\Delta}V$) for the mission. In this paper we review an analytical approach which is suitable enough for preliminary conceptual design and is used previously to optimize stage configurations for Two Stage to Orbit SLV for Low Earth Orbit(LEO) Missions; we have extended this approach to Three Stage to Orbit SLV and compared different propellant options for the mission. The objective is to minimize the Gross Lift off Weight(GLOW). The primary performance figures of merit were the total inert weight of the SLV and the payload weight that the SLV could lift into LEO, given candidate propulsion systems. The optimization is achieved by configuring the $}\Delta}V$ between stages. A comparison of configurations of single-stage and multi-stage SLVs is made for different propellants. Based upon the optimized stage configurations a comparative performance analysis is made between Liquid and Solid fueled SLV. A 3 degree of freedom trajectory-analysis program is modeled in SIMULINK and used to conduct the performance analysis. Furthermore, a cost analysis is performed on our stage optimized SLVs. The cost estimation relationships(CER) used give us a comparison of development and fabrication costs for the Liquid vs. Solid fueled SLV in man years. The pros and cons of the production, operation ability, performance, responsiveness, logistics, price, shelf life, storage etc of both Solid and Liquid fueled SLVs are discussed. The statistics and data are used from existing or historical(real) SLV stages.

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Theoretical Analysis on the Applications of the Double-Floor Ondol System (이중 바닥 온돌 시스템의 응용에 관한 이론적 분석)

  • Choi, Won-Ki;Lee, Kang-Young;Lee, Hyun-Geun;Suh, Seung-Jik
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.19 no.5
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    • pp.355-363
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    • 2007
  • The Korean traditional 'Ondol' system has been a target for innovation to meet the requirements of sustainable domestic building and low carbon emission energy utilization. Simulation techniques provide designers and researchers with powerful tools to predict heating load and thermal behaviour of Ondol systems installed in various contexts. However, there are few studies on Ondol models, especially associated with multi-stories buildings of which type covers about 50% of Korean housing stock. In this study, we analyzed the double floor Ondol system on the multi-stories buildings using the ESP-r program. On the basis of the double floor Ondol system, we suggested the new modelling method that is composed of the Vent zone and Ondol zone. Using the this model, sensitivity analysis was carried out to refine the applicability of the model taking account of control conditions, constructions, air change and air flow network method and CFD analysis using the FLUENT. The air layer has enough temperature to use in heating zone. It is suggested that the simplicity of the model will allow building designers and mechanical engineers easily to implement scenario-based assessments of design options as well as control strategies. Later, we will simulate the real buildings and analyze the air distributions using the Fluent according to the various conditions.

Production of Farm-level Agro-information for Adaptation to Climate Change (기후변화 대응을 위한 농장수준 농업정보 생산)

  • Moon, Kyung Hwan;Seo, Hyeong Ho;Shin, Min Ji;Song, Eung Young;Oh, Soonja
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.21 no.3
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    • pp.158-166
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    • 2019
  • Implementing proper land management techniques, such as selecting the best crops and applying the best cultivation techniques at the farm level, is an effective way for farmers to adapt to climate change. Also it will be helpful if the farmer can get the information of agro-weather and the growth status of cultivating crops in real time and the simulated results of applying optional technologies. To test this, a system (web site) was developed to produce agro-weather data and crop growth information of farms by combining agricultural climate maps and crop growth modeling techniques to highland area for summer-season Chinese cabbage production. The system has been shown to be a viable tool for producing farm-level information and providing it directly to farmers. Further improvements will be required in the speed of information access, the microclimate models for some meteorological factors, and the crop growth models to test different options.

Analysis of total mixed ration (TMR) nutrition and metabolic diseases in Korean dairy farm (국내 고능력우 Holsteins 농가의 TMR 영양성분 및 대사성 질병 분석)

  • Kim, SeonHo;Cho, Yong-il
    • Korean Journal of Veterinary Service
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    • v.42 no.2
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    • pp.67-71
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    • 2019
  • A variety of livestock feed resources were used in Korean dairy farm due to a lack of the endemic feed. However, there is inadequate real farm data to support farmers' decisions on the choice of options. The main objective of this study was to evaluate the nutritional value of total mixed ration (TMR) as well as the metabolic diseases status in Korean dairy farms. TMR samples were collected from nine feed companies and eight selected self-formulated by the dairy farms. The nutrient contents were examined by AOAC methods. The frequency of metabolic diseases such as ketosis and hypocalcemia were surveyed. The average moisture content was 36.2% although the min. and max. value were varied from 21.7% and 50.6% among farms. The mean${\pm}$standard deviation of crude fiber (CF), crude ash (CA), ether extract (EE), and crude protein (CP) were $21.4{\pm}2.5$, $4.6{\pm}0.4$, $3.2{\pm}0.5$ and $9.8{\pm}1.7$, respectively. However, the average ADF and NDF was $17.3{\pm}3.7$ and $31.0{\pm}5.7$, respectively. The compositions of TMR were varied significantly among the dairy farms. The frequency of clinical Ketosis (CK), subclinical ketosis (SCK) and hypocalcemia were higher in early lactation period with 4.5%, 11.0% and 3.0%, respectively. Also, the frequency of SCK was higher than CK and hypocalcemia throughout the lactation. Periodic TMR nutrient analysis based on herd production or physiology change would maximize the effects of TMR feeding. Furthermore, the study results would be useful to the farm practitioner and producer for their farm management.

Anti-microbial and anti-inflammatory effects of Cheonwangbosim-dan against Helicobacter pylori-induced gastritis

  • Park, Hee-Seon;Jeong, Hye-Yun;Kim, Young-Suk;Seo, Chang-Seob;Ha, Hyekyung;Kwon, Hyo-Jung
    • Journal of Veterinary Science
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    • v.21 no.3
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    • pp.39.1-39.15
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    • 2020
  • Background: There are various Helicobacter species colonizing the stomachs of animals. Although Helicobacter species usually cause asymptomatic infection in the hosts, clinical signs can occur due to gastritis associated with Helicobacter in animals. Among them, Helicobacter pylori is strongly associated with chronic gastritis, gastric ulcers, and gastric cancers. As the standard therapies used to treat H. pylori have proven insufficient, alternative options are needed to prevent and eradicate the diseases associated with this bacterium. Cheonwangbosim-dan (CBD), a traditional herbal formula that is popular in East Asia, has been commonly used for arterial or auricular flutter, neurosis, insomnia, and cardiac malfunction-induced disease. Objectives: The present study investigated the antimicrobial effect of CBD on H. pylori-infected human gastric carcinoma AGS cells and model mice. Methods: AGS cells were infected with H. pylori and treated with a variety of concentrations of CBD or antibiotics. Mice were given 3 oral inoculations with H. pylori and then dosed with CBD (100 or 500 mg/kg) for 4 weeks or with standard antibiotics for 1 week. One week after the last treatment, gastric samples were collected and examined by histopathological analysis, real-time quantitative polymerase chain reaction, and immunoblotting. Results: Our results showed that CBD treatment of AGS cells significantly reduced the H. pylori-induced elevations of interleukin-8, inducible nitric oxide synthase (iNOS), and cyclooxygenase-2 (COX-2). In the animal model, CBD treatment inhibited the colonization of H. pylori and the levels of malondialdehyde, inflammation, proinflammatory cytokines, iNOS, and COX-2 in gastric tissues. CBD also decreased the phosphorylation levels of p38 mitogen-activated protein kinase family. Conclusions: This study suggests that CBD might be a prospective candidate for treating H. pylori-induced gastric injury.