• Title/Summary/Keyword: re-infection

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Changing Patterns of Serum and Bile Antibodies in Re-infected Rats with Clonorchis sinensis

  • Zhang, Hong-Man;Chung, Byung-Suk;Li, Shun-Yu;Choi, Min-Ho;Hong, Sung-Tae
    • Parasites, Hosts and Diseases
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    • v.46 no.1
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    • pp.17-22
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    • 2008
  • Rats develop strong resistance to re-infection and super-infection by Clonorchis sinensis. The present study investigated the antibodies present in the sera and bile juice of rats that were primary infected and re-infected with C. sinensis. The serum level of specific IgG antibodies, which were elevated 2 wk of the primary infection, peaked at 4 wk and subsequently remained unchanged even during re-infection. The total IgE level in serum increased slowly from 388 ng / ml to 3,426 ng / ml beginning 2 wk after the primary infection, and remained high up to 8 wk but dropped to a normal level (259 ng / ml) after treatment. In resistant re-infected rats, the serum IgE level increased rapidly and peaked within 1 wk, whereas no increase was observed in immunosuppressed rats. The serum level of specific IgA antibodies was elevated beginning 1 wk after infection, and decreased 4 wk after treatment. The total bile IgA level unchanged during the primary infection but increased in treated and re-infected rats. The elevated levels of serum IgE and bile IgA indicate that these immunoglobulins may be correlated with the development of resistance to re-infection by C. sinensis in rats.

Clinical treatment of postoperative infection following sinus augmentation

  • Hong, Seung-Bum;Kim, Jae-Suk;Shin, Seung-Il;Han, Ji-Young;Herr, Yeek;Chung, Jong-Hyuk
    • Journal of Periodontal and Implant Science
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    • v.40 no.3
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    • pp.144-149
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    • 2010
  • Purpose: The aim of this case report is to present the successful clinical treatment of two cases of postoperative infection following maxillary sinus augmentation. Methods: In the two cases of postoperative infection, immediate total removal of the grafted material from the sinus was conducted to stop the spread of the infection, after which a high dose of antibiotics was administrated. Re-augmentation procedures were then conducted after the infection subsided. Results: No further complications occurred after sinus re-augmentation. The dental implants placed in the re-augmented sinus were clinically osseointegrated, and the implant-supported restorations in the two cases of postoperative infection have been functioning very well for over 2 years. Conclusions: In the case of infection of the grafted sinuses, it is necessary to completely remove the graft materials and then administer a high dose of antibiotics to treat the acute infection, after which sinus re-augmentation is suggested.

Survey of the real-world re-use of disposable dental supplies in dental offices

  • Park, Bo-Young;Mun, So-Jung;Chung, Won-Gyun;Choi, Eun-Sil;Noh, Hie-Jin
    • Journal of Korean society of Dental Hygiene
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    • v.19 no.1
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    • pp.141-149
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    • 2019
  • Objectives: To investigate the real-world re-use of disposable dental supplies (DDS) in dental offices and assess the relationship between general characteristics of dental hygienists and reuse of DDS, with respect to infection control characteristics. Methods: A questionnaire was administered to 277 dental hygienists to assess their general characteristics, awareness of infection control/DDS management, and re-use of DDS. Nine DDS were categorized into the following categories based on their purpose: Critical, Semicritical, Noncritical, and Personal protective equipment (PPE). The association between general characteristics of dental hygienists and re-use of DDS, with respect to infection control characteristics, was assessed using the chi-squared test. Results: All 9 DDS were re-used to different extents. The highest reuse rate of supplies were for masks (64.6%), prophylaxis cups (61.0%) and plastic saliva ejectors (30.0%). Overall, 89.5% of the participants re-used DDS; subgroup analysis showed the following proportions of specific DDS re-use: PPE 66.4%; Semicritical DDS 63.9%; Noncritical DDS 19.5%; and Critical DDS 1.8%. Based on the type of clinic, the rate of re-use was higher in dental clinics than dental hospitals. Thus, the re-use of DDS may be caused by inappropriate or nonexistent guidelines or habitual practice, rather than the awareness or attitude of dental hygienists. Conclusions: In order to ensure a safe environment within the dental clinic, DDS classifications must be clearly outlined in the dental infection control guidelines; moreover, additional studies are needed regarding the regulations for DDS re-use and disposal.

A study on re-use intention through external stimuli and infection control of dental office perceived by medical consumer (의료소비자가 인식하는 치과의원의 감염관리와 외부자극을 통한 재이용의사에 관한 연구)

  • Cho, Min-Jeong
    • Journal of Korean society of Dental Hygiene
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    • v.11 no.4
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    • pp.571-580
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    • 2011
  • Objectives : This study focused on examine the relevance between behavioral changes of customers and re-use intention on medical institution after experiencing infection control through external stimuli. Methods : This research was based on self-standing survey conducted from August to November 2010, 214 people who randomly selected from five dental clinics located in Busan were analyzed as the final group. Collected data were performed using SPSS 12.0 for Window. Results : 1. 82.8% of those surveyed who experienced external stimulation have changed their behavior on hospital environments and facilities, and 80.5% of them answered the stimuli influenced their re-use intention on medical institution. 2. There were no significant differences between participants by general characteristics on 'The reason why medical team wear sanitary appliances'. In age group 30~39, 85.4% of participants chose the answer so the difference were statistically significant(p<.001). Result by household income showed significant difference in group over $1,000 to $2,000 as 82.7% response(p<.05). 3. 94.4% of participants chose 'Required' for both surgical suits and gloves in research of 'The necessity level of personal sanitary appliances' which medical teams wear for treatment and 79.4% agreed that medical teams need to change their medical gloves whenever treating each patients. 4. The survey revealed that the most important appliance in patient's awareness were surgical gloves and protective goggles has chosen as the least important one. Conclusions : Patients as medical consumer were highly noticed of importance of the infection control in dental clinic and necessity of personal sanitary appliances. The patients who has accessed dental infection control information by external stimuli in advance showed objectival changes of their visit and behavioral changes with bringing medical environments together. This aspects influenced those patient's re-use intention in conclusion.

Immunoactivity of Ginsenosides Re and Rg1 that Enhances Resistance of Mice Against Experimental Disseminated Candidiasis

  • Han, Yong-Moon;Jin, Byung-Suk;Ko, Sung-Kwon;Lee, Jue-Hee
    • Natural Product Sciences
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    • v.10 no.3
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    • pp.134-139
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    • 2004
  • In this study, an immunoactivity of panaxtriol ginsenosides Re and Rg1 against infection due to Candida albicans was investigated. The ginsenosides were extracted from Red Ginseng with 85% ethanol and heat-treatment and were analyzed by HPLC on water-acetonitrile as a mobile phase. The HPLC analysis revealed that the extract contained ginsenosides Re and Rg1, which were eluted as a combined peak. By agar diffusion susceptibility, the mixture of Re and Rg1 had no growth-inhibitory activity on C. albicans yeast cells. However, in animal tests BALB/c mice given the mixture of Re and Rg1 intraperitoneally (Lp.) before intravenous (Lv.) infection with live C. albicans yeast cells had longer mean survival times (MST) than MST of control mice groups that received only buffer solution instead of Re and Rg1. In experiments 60% of the ginsenosides-treated mice survived the entire duration of the 50-day observation. The Re and Rg1 mixture induced production of nitric oxide when interacted with RAW 264.7 macrophage cell line. In addition, the mixture caused morphological change of the macrophages. These data indicate that immunostimulation by the Re and Rg1 may be responsible for the protection of mice against disseminated candidiasis.

Re-Examination of Opisthorchis viverrini in Nakhon Ratchasima Province, Northeastern Thailand, Indicates Continued Needs for Health Intervention

  • Kaewpitoon, Soraya J;Rujirakul, Ratana;Loyd, Ryan A;Panpimanmas, Sukij;Matrakool, Likit;Tongtawee, Taweesak;Kompor, Porntip;Norkaew, Jun;Chavengkun, Wasugree;Kujapan, Jirawoot;Polphimai, Sukanya;Phatisena, Tanida;Eaksunti, Thawatchai;Polsripradist, Poowadol;Padchasuwan, Natnapa;Kaewpitoon, Natthawut
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.1
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    • pp.231-234
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    • 2016
  • Opisthorchis viverrini infection is associated with cholangiocarcinoma particularly in the cases of chronic or re-infection. This presents a serious health problem in northeastern and northern Thailand. A community base approach is required for surveillance. Therefore, in a pilot project, re-examination of O. viverrini infection was conducted in the 3 districts of Nakhon Ratchasima province, Thailand, during June and October 2015. A total of 355 participants from a 194,152 population, was selected through multi-stage sampling. O. viverrini infection was determined using modified Kato Katz thick smear technique. Participants were 229 males and 126 females, and aged ${\geq}30$ years old. Prevalence of O. viverrini infection was 2.25% (8/355 participants). O. viverrini infection was slightly higher in females (3.17%), and age group between 41-50 years (4.49%). Mueang Yang district had a highest of O. viverrini infection rate (2.82%), and followed by Bua Yai (2.48%), and Chum Phuang (1.84%), respectively. O. viverrini infection rate was increased from year 2012 to 2015 particularly in Bua Yai and Mueang Yang. These re-examinion results indicate that opisthorchiasis is still problem in community of Nakhon Ratchasima province, therefore, the provincial-wide scale is need required. Furthermore health education is need intervened in the infected group, and screening of cholangiocarcinoma is urgently concerned.

Current Status of Epidemiology, Diagnosis, Therapeutics, and Vaccines for the Re-Emerging Human Monkeypox Virus

  • Wooseong Lee;Yu-Jin Kim;Su Jin Lee;Dae-Gyun Ahn;Seong-Jun Kim
    • Journal of Microbiology and Biotechnology
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    • v.33 no.8
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    • pp.981-991
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    • 2023
  • Monkeypox (Mpox) virus, a member of the Poxviridae family, causes a severe illness similar to smallpox, which is characterized by symptoms such as high fever, rash, and pustules. Human-to-human transmission cases have been reported but remained low since the first recorded case of human infection occurred in the Congo in 1970. Recently, Mpox has re-emerged, leading to an alarming surge in infections worldwide since 2022, originating in the United Kingdom. Consequently, the World Health Organization (WHO) officially declared the '2022-23 Mpox outbreak'. Currently, no specific therapy or vaccine is available for Mpox. Therefore, patients infected with Mpox are treated using conventional therapies developed for smallpox. However, the vaccines developed for smallpox have demonstrated only partial efficacy against Mpox, allowing viral transmission among humans. In this review, we discuss the current epidemiology of the ongoing Mpox outbreak and provide an update on the progress made in diagnosis, treatment, and development of vaccines for Mpox.

An Analysis of Spectral Pattern for Detecting Pine Wilt Disease Using Ground-Based Hyperspectral Camera (지상용 초분광 카메라를 이용한 소나무재선충병 감염목 분광 특성 분석)

  • Lee, Jung Bin;Kim, Eun Sook;Lee, Seung Ho
    • Korean Journal of Remote Sensing
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    • v.30 no.5
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    • pp.665-675
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    • 2014
  • In this paper spectral characteristics and spectral patterns of pine wilt disease at different development stage were analyzed in Geoje-do where the disease has already spread. Ground-based hyperspectral imaging containing hundreds of wavelength band is feasible with continuous screening and monitoring of disease symptoms during pathogenesis. The research is based on an hyperspectral imaging of trees from infection phase to witherer phase using a ground based hyperspectral camera within the area of pine wilt disease outbreaks in Geojedo for the analysis of pine wilt disease. Hyperspectral imaging through hundreds of wavelength band is feasible with a ground based hyperspectral camera. In this research, we carried out wavelength band change analysis on trees from infection phase to witherer phase using ground based hyperspectral camera and comparative analysis with major vegetation indices such as Normalized Difference Vegetation Index (NDVI), Red Edge Normalized Difference Vegetation Index (reNDVI), Photochemical Reflectance Index (PRI) and Anthocyanin Reflectance Index 2 (ARI2). As a result, NDVI and reNDVI were analyzed to be effective for infection tree detection. The 688 nm section, in which withered trees and healthy trees reflected the most distinctions, was applied to reNDVI to judge the applicability of the section. According to the analysis result, the vegetation index applied including 688 nm showed the biggest change range by infection progress.

A study on the state of infection control in dental clinic (치과진료실에서의 감염관리 실태 조사)

  • Kim, Kyung-Mi;Jung, Jae-Yeon;Hwang, Yoon-Sook
    • Journal of Korean society of Dental Hygiene
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    • v.7 no.3
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    • pp.213-230
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    • 2007
  • The purpose of this study was to examine the state of infection control provided to members of Korean Dental Hygienists Association. The subjects in this study were dental hygienists who attended a symposium on July 1. 2006. after a survey was conducted, the answer sheets from 489 participants were analyzed, and the findings of the study were as follows: 1. Possession of disinfection room was being(72.7%), and person of infection control was zero(52.9%). Number of sterilizer was one(62.2%). 2. As a repetition choice, type of sterilizer was autoclave(97.9%), UV sterilizer(67.4%) and EO gas sterilizer(21.4%). As a repetition choice, infection materials was ethanol(84.1%). 3. Water tube of unit and chair was using of sterilized water(42.9%). Sterilizing of compressed air was no(69.0%). 4. Re-using of disposal was not using(62.5%), re-using disposal was suction tip(28.2%)(repetition choice) 5. In sterilization of instruments, hand-piece was every using time(28.4%), and reamer-file, bur, mirror, pincette, explorer, hand scaler and ultrasonic scaler were high in every using time. 6. Individual protection was high of using, cleaning of hands before treatment was every treatment(87.0%). Type of soap was liquid type in dental clinic(48.2%), infection soap in dental hospital(41.2%) and solid soap in public health center(50.6%). Answered that they need regular oral health education, and 82.9% respondents answered that they need oral health technicians in school. And 87.8% respondents needed individual oral health education for the benefit of better oral health.

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Differences in dental hygienists' infection control awareness and re-user rate of disposable dental care supplies (치과위생사의 일회용 치과진료용품 감염관리 인지도와 재사용자율의 차이)

  • Park, Bo-Young;Noh, Hie-Jin
    • Journal of Korean society of Dental Hygiene
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    • v.20 no.5
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    • pp.645-653
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    • 2020
  • Objectives: The purpose of this study is to identify the difference between the awareness and reuser rate of infection control t for disposable dental care supplies (DDCS) according to general characteristics and infection management-related characteristics. Methods: A questionnaire was used for 277 dental hygienists to check the general characteristics, infection management-related characteristics, awareness of infection control disposable dental care products, syringe needle, prophylaxis cup, prophylaxis brush, plastic saliva ejector, orthodontic bracket, and gloves reuse rate. Results: The awareness of infection control for DDCS differed according to 'hospital type', 'average number of patients per day', 'presence or absence of infection control guidelines', and 'experience in infection management training in the last two years' (p<0.05). Reuser rates of disposable dental care products differed according to 'hospital type', 'average number of patients per day', 'presence or absence of infection control guidelines', and 'experience in infection management training in the last two years' (p<0.05). Conclusions: In order to manage infection of DDCS, the level of infection control system in the workplace is improved and support for related education is needed. In addition, guidelines and regulations on prohibition of reuse and classification criteria for various DDCS should be prepared.