DOI QR코드

DOI QR Code

Re-Examination of Opisthorchis viverrini in Nakhon Ratchasima Province, Northeastern Thailand, Indicates Continued Needs for Health Intervention

  • Published : 2016.02.05

Abstract

Opisthorchis viverrini infection is associated with cholangiocarcinoma particularly in the cases of chronic or re-infection. This presents a serious health problem in northeastern and northern Thailand. A community base approach is required for surveillance. Therefore, in a pilot project, re-examination of O. viverrini infection was conducted in the 3 districts of Nakhon Ratchasima province, Thailand, during June and October 2015. A total of 355 participants from a 194,152 population, was selected through multi-stage sampling. O. viverrini infection was determined using modified Kato Katz thick smear technique. Participants were 229 males and 126 females, and aged ${\geq}30$ years old. Prevalence of O. viverrini infection was 2.25% (8/355 participants). O. viverrini infection was slightly higher in females (3.17%), and age group between 41-50 years (4.49%). Mueang Yang district had a highest of O. viverrini infection rate (2.82%), and followed by Bua Yai (2.48%), and Chum Phuang (1.84%), respectively. O. viverrini infection rate was increased from year 2012 to 2015 particularly in Bua Yai and Mueang Yang. These re-examinion results indicate that opisthorchiasis is still problem in community of Nakhon Ratchasima province, therefore, the provincial-wide scale is need required. Furthermore health education is need intervened in the infected group, and screening of cholangiocarcinoma is urgently concerned.

Keywords

References

  1. Harinasuta C, Vajrasthira S (1960). Opisthorchiasis in Thailand. Am J Trop Med Hyg, 54, 100-5.
  2. Harinasuta T, Riganti M, Bunnag D (1984). Opisthorchis viverrini infection: pathogenesis and clinical features. Arzneimittelforschung, 34, 1167-9.
  3. IARC. (1994). Infection with liver flukes (Opisthorchis viverrini, opisthorchis felineus and clonrochis sinensis). IARC Monogr Eval Carcinog Risks Hum, 61, 121-75.
  4. Jongsuksuntigul P, Imsomboon T (2003). Opisthorchiasis control in Thailand. Acta Trop, 88, 229-32. https://doi.org/10.1016/j.actatropica.2003.01.002
  5. Kaewpitoon N, Kaewpitoon SJ, Pengsaa P (2008). Opisthorchiasis in Thailand: review and current status. World J Gastroenterol, 14, 2297-302. https://doi.org/10.3748/wjg.14.2297
  6. Meireles LR, Tsutsui VS, Carmo CV, et al (2008). Quantitative Toxoplasma gondii oocyst detection by a modified Kato Katz test using Kinyoun staining (KKK) in ME49 strain experimentally infected cats. Rev Inst Med Trop S Paulo, 50, 187-90. https://doi.org/10.1590/S0036-46652008000300010
  7. Royal Gazette (1939). Royal gazette of district, sub-district in Thailand, 354-64.
  8. Sadun EH (1995). Studies on Opisthorchis viverrini in Thailand. Am J Hyg, 62, 81-115.
  9. Sithithaworn P, Andrews RH, Nguyen VD, et al (2012). The current status of opisthorchiasis and clonorchiasis in the Mekong Basin. Parasitol Internat, 61, 10-6. https://doi.org/10.1016/j.parint.2011.08.014
  10. Sripa B, Kaewkes S, Intapan PM, et al (2010). Food-borne trematodiases in Southeast Asia: epidemiology, pathology, clinical manifestation and control. Adv Parasitol, 72, 305-50. https://doi.org/10.1016/S0065-308X(10)72011-X
  11. Sripa B, Pairojkul C (2008). Cholangiocarcinoma: lessons from Thailand. Curr Opin Gastroenterol, 24, 349-56. https://doi.org/10.1097/MOG.0b013e3282fbf9b3
  12. Sripa B, Tangkawattana S, Laha T, et al (2015). Toward integrated opisthorchiasis control in northeast Thailand: the Lawa project. Acta Trop, 141, 361-7. https://doi.org/10.1016/j.actatropica.2014.07.017
  13. Thamavit W, Bhamarapravati N, Sahaphong S, et al (1978). Effects of dimethylnitrosamine on induction of cholangiocarcinoma in Opisthorchis viverrini-infected Syrian golden hamsters. Cancer Res, 38, 4634-9.

Cited by

  1. Health Behavior Regarding Liver Flukes among Rural People in Nakhon Ratchasima, Thailand vol.17, pp.4, 2016, https://doi.org/10.7314/APJCP.2016.17.4.2111