• Title/Summary/Keyword: re-evaluation

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Systematic review of the effect of omega-3 fatty acids on improvement of blood flow while focused on evaluation of claims for health functional food (건강기능식품의 기능성을 중심으로 한 오메가-3 지방산 함유유지의혈행개선 효과에 대한 체계적 고찰)

  • Jeong, Sewon;Kim, Ji Yeon;Paek, Ju Eun;Kim, Joohee;Kwak, Jin Sook;Kwon, Oran
    • Journal of Nutrition and Health
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    • v.46 no.3
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    • pp.226-238
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    • 2013
  • Omega-3 polyunsaturated fatty acids are essential fatty acids because humans cannot synthesize them de novo and must obtain them in their diet. Fish and fish oil are rich sources of omega-3 fatty acids, including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Significant evidence of the beneficial role of dietary intake of omega-3 fatty acids in blood flow has been reported and putative mechanisms for improvement of blood flow include anti-thrombotic effects, lowered blood pressure, improved endothelial function, and anti-atherogenic effects. Edible oils containing omega-3 fatty acids were registered as functional ingredients in the Korea Health Functional Food Code. Although omega-3 fatty acids have been evaluated by the Korea Food and Drug Administration (KFDA) based on scientific evidence, periodic re-evaluation may be needed because emerging data related to omega-3 fatty acids have accumulated. Therefore, in this study, we re-evaluated scientific evidence for the effect of omega-3 fatty acids as a functional ingredient in health functional food on improvement of blood flow. A comprehensive literature search was conducted for collection of relevant human studies using the Medline and Cochrane, KISS, and IBIDS databases for the years 1955-2012. Search keywords were used by combination of terms related to omega-3 fatty acids and blood flow. The search was limited to human studies published in Korean, English, and Japanese. Using the KFDA's evidence based evaluation system for scientific evaluation of health claims, 112 human studies were identified and reviewed in order to evaluate the strength of the evidence supporting a relation between omega-3 fatty acids and blood flow. Among 112 studies, significant effects on improvement of blood flow were reported in 84 studies and the daily intake amount was ranged from 0.1 to 15 g. According to this methodology of systematic review, we concluded that there was possible evidence to support a relation between omega-3 fatty acid intake and blood flow. However, because inconsistent results have recently been reported, future studies should be monitored.

Systematic Review of the Effect of Glucosamine on Joint Health while Focused on the Evaluation of Claims for Health Functional Food (건강기능식품의 기능성을 중심으로 한 글루코사민의 관절건강 기능성에 대한 체계적 고찰)

  • Kim, Joohee;Kim, Ji Yeon;Kwak, Jin Sook;Paek, Ju Eun;Jeong, Sewon;Kwon, Oran
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.43 no.2
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    • pp.293-299
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    • 2014
  • Although the functional ingredient has been evaluated based on scientific evidence by the Ministry of Food and Drug Safety (MFDS), the levels of scientific evidence and consistency of the results might vary according to the emerging data. Therefore, a periodic re-evaluation may be needed in some functional ingredients. In this study, we re-evaluated the scientific evidence for the joint health of glucosamine as a functional ingredient in health functional food. Literature searches were conducted using Pubmed, Cochrane, KISS, and IBIDS databases with the search term of glucosamine in combination with osteoarthritis. The search was limited to human studies published in English, Korean and Japanese. Using the MFDS's evidence based evaluation system for scientific evaluation of health claims, 34 human studies were identified and reviewed in order to evaluate the strength of the evidence supporting the relation between glucosamine and joint health. Among the 34 studies, significant effects for joint health were reported in 28 studies, and their daily intake amount was 1.5 to 2 g. Eleven out of 34 studies were identified, excluding severe radiographic osteoarthritis, and ten from those eleven studies reported significant effects for joint health. Based on this systematic review, we concluded that there was possible evidence to support a relation between glucosamine intake and joint health.

The Effects of Physical Environment, Perceived Justice and Perceived Waiting-Time on Repurchase Intension (의료서비스에서 물리적 환경, 공정성, 지각된 대기시간이 재이용의도에 미치는 영향)

  • Yoon, Sung-Wook;Kim, Su-Bae
    • Journal of Global Scholars of Marketing Science
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    • v.12
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    • pp.135-154
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    • 2003
  • This study having purpose of promoting the convenience of medical service customer at medical service encounter have tried to know the influence of physical environment, perceived justice, and perceived waiting time to the intention of re-use of medical service through mediating variable such as service Quality evaluation and negative emotion. Particularly, this exploratory study have first tried to know what influence the physical environment and perceived justice have on negative emotion. Findings are; First, the physical environment affect positive influence to service Quality evaluation, and lower the negative emotion. Second, perceived justice have no influence to the service Quality evaluation and negative emotion. Third, the perceived waiting time lower the service Quality and increase the negative emotion. Fourth, the service Quality have positive influence to intention of re-use of medical service. However, the negative emotion have no influence to the intention of re-use of medical service. Therefore physical environment of medical service becomes more important and it is necessary to shorten the waiting time. In addition, even though negative emotion have no influence to the intention of re-use of medical service it is necessary to make the smallest of negative emotion. Because it is possible to separate once switching barner due to the medical service specificity is solved.

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Accuracy Analysis of Network RTK Surveying for Cadastral Re-survey Project (지적재조사사업에서 Network RTK 측량의 적용 정확도 분석)

  • Park, Chun Soo;Park, Ki Heon;Hong, Sung Eon
    • Journal of Korean Society for Geospatial Information Science
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    • v.21 no.4
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    • pp.117-123
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    • 2013
  • The purpose of this research is to suggest the reasonable method of Network RTK surveying in future cadastral re-survey project through the accuracy analysis about Network RTK surveying achievement and the conventional TS-based confirmation surveying. To achieve it, we selected the experiment places and succeeded in achieving the result by Network RTK surveying about total of 307 parcel boundary point. We compared it with the result of confirmation surveying for cadastral, and it was shown that total connection errors of RMSE was ${\pm}0.1028m$ and total 48 places exceeded in the cadastral re-survey allowable error tolerance. The research suggested the practical alternatives in cadastral re-survey project after the comprehensive evaluation of those analysis results. Therefore, the author suggested development and adoptation of integrated electronic plane table surveying method. Moreover, we suggested unifying the first parcel boundary point method into the total station surveying and adopt the Network RTK surveying on the cadastral surveying inspection.

Economic evaluation analysis for accommodation re-arrangement of 9,600TEU Container ship (9,600TEU급 컨테이너선의 거주 공간 재배치에 의한 경제성 평가 분석)

  • Choi, Kyong-Soon;Im, Nam-Kyun
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • v.29 no.1
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    • pp.325-332
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    • 2005
  • As ship builder companies have a tendency to pursuit the effect of scale economy, recently the ultra-large sized container ship is discussed very actively among them. It is expected that these situation will be continued for the time being. The need of accommodation re-arrangement is carefully proposed according to the tendency of ultra-large sized ship. In this paper, accommodation re-arrangement of ultra-large container ship is examined in the view of economy. We proposed separation of engine room and accommodation part through review and supplementaition of drawing generation in intial design stage. Also we investigated its merits and demerits to find out whether it can be realized or not in the view of economical efficiency. The RFR(Required Freight Rate) is considered as the objective function to evaluate the re-designed vessel. The economical benefits for increasing the number of TEU(Twenty-foot Equivalent Units)'s and the re-arranged space are analyzed in the view of ship owner and shipyards respectively.

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Evaluation of Performance of Atmospheric Re-Entry System for the Uncertainties Using the Monte-Carlo Simulation (몬테-칼로 모의실험을 이용한 대기권 재진입 시스템의 불확실성 성능 평가)

  • Lee, Dae-Woo;Cho, Kyeum-Rae;Oh, Se-Jong
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.30 no.7
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    • pp.51-60
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    • 2002
  • The Monte-Carlo simulation of statistical analysis is used to investigate the final conditions of states as well as the footprint boundaries resulting from the atmospheric re-entry dispersions. The re-entry dispersions in this paper are specified by a $7\times7$ covariance matrix of latitude, longitude, altitude, bank angle, flight path angle, heading error, and range at entry velocity. The error sources that affect these at re-entry for a deboost are the uncertainties associated with atmospheric density and temperature, initial errors, wind, and estimation error of aerodynamic coefficients. Using $3{\sigma}_n$ deviations of these errors and a nominal flight trajectory, the covariance matrix of state variables can be determined by performing a trajectory error analysis. Major considerations in the application of the Monte-Carlo method are the simulation of perturbed trajectories, bank reversal, and determination of the impact points for each of these trajectories. This paper analyzes the results of uncertainties from the viewpoint of aero-coefficients and bank reversal.