• KSII Transactions on Internet and Information Systems (TIIS)
• /
• v.12 no.11
• /
• pp.5269-5286
• /
• 2018

Task scheduling is one of the key issues in improving system performance and optimizing resource management in cloud computing environment. In order to provide appropriate services for heterogeneous users, we propose a novel task scheduling strategy with service differentiation, in which the delay sensitive tasks are assigned to the rapid cloud with high-speed processing, whereas the fault sensitive tasks are assigned to the reliable cloud with service restoration. Considering that a user can receive service from either local SaaS (Software as a Service) servers or public IaaS (Infrastructure as a Service) cloud, we establish a hybrid queueing network based system model. With the assumption of Poisson arriving process, we analyze the system model in steady state. Moreover, we derive the performance measures in terms of average response time of the delay sensitive tasks and utilization of VMs (Virtual Machines) in reliable cloud. We provide experimental results to validate the proposed strategy and the system model. Furthermore, we investigate the Nash equilibrium behavior and the social optimization behavior of the delay sensitive tasks. Finally, we carry out an improved intelligent searching algorithm to obtain the optimal arrival rate of total tasks and present a pricing policy for the delay sensitive tasks.

• Korean Journal of Microbiology
• /
• v.46 no.3
• /
• pp.233-239
• /
• 2010

Four genes (yqfR, yfmL, ydbR, deaD) were identified as putative DEAD-box RNA helicase genes in the genomic sequence of Bacillus subtilis by homology search. To understand the function of these genes, each of the genes was deleted and the constructed strains were tested for their growth charateristics at different temperatures. The growth rate of ydbR deletion mutant ($T_d$=53 min) was a little bit reduced at $37^{\circ}C$ as compared to that of wild type strain (CU1065). But the growth rate of other three (yqfR, yfmL, deaD) deletion mutants ($T_d$=30-40 min) is nearly equal to the growth rate of wild type ($T_d$=32 min). On the other hands, the growth rate of deletion mutants were reduced at $22^{\circ}C$ in order of yqfR ($T_d$=151 min), yfmL ($T_d$=214 min), ydbR ($T_d$=343 min), which showed cold-sensitive phenotype. The deletion mutant of deaD ($T_d$=109 min) grew equally as compared to the growth rate ($T_d$=102 min) of the wild type at $22^{\circ}C$ and did not show cold-sensitive growth. Double, triple and quadruple deletion mutants of these genes were constructed, and growth rate of these mutants were measured at various temperature conditions ($22^{\circ}C$, $37^{\circ}C$, $42^{\circ}C$) using LB broth. Multiple deletion mutations showed more severe cold-sensitive growth than single deletion mutations, and double deletion of ydbR and yfmL ($T_d$=984 min) showed most cold-sensitive growth than any other double mutants. Such a cold-sensitive growth of these mutations is quite similar to the result of csdA or srmB deletion in E. coli and suggested that physiological role of ydbR and yfmL is related with ribosome assembly.

• Proceedings of the PSK Conference
• /
• 2003.04a
• /
• pp.283.2-283.2
• /
• 2003

This study established a highly sensitive novel quantification method for detecting felodipine in human plasma using LC-MS/MS. The mobile phase used after degassing was composed of 1 mM ammonium acetate and acetonitrile (20:80, pH 6.0), with flow rate of 200 uL/min. One mL plasma were pipetted into glass tubes and spiked with 0.1 mL of internal standard solution. (omitted)

• Proceedings of the IEEK Conference
• /
• 1998.10a
• /
• pp.75-78
• /
• 1998

In this paper, we propose a new cell discarding and scheduling scheme which reduce cell loss rate by measuring, in real time, the number of discarded cells in the queuing system with a different loss priority for each class of service such that each class of service meets its cell loss rate requirements and reduce average delay rate for the traffic that is sensitive in cell delay in output buffer of the ATM switch. Throughout the computer simulation, the existing scheduling scheme and proposed scheme are compared with respect to cell loss rate and average delay time.

• Journal of Environmental Science International
• /
• v.25 no.7
• /
• pp.951-961
• /
• 2016

To prevent increasing instances of heat-related illnesses due to heat waves generated by climate change, a customized thermal environment index should be developed for outdoor workers. In this study, we conducted sensitivity analysis of the Masan harbor during a heat wave period (August 9th to 15th, 2013) using the MENEX model with metabolic rate and clothing-insulation data, in order to obtain realistic information about the thermal environment. This study shows that accurate input data are essential to gather information for thermophysiological indices (PST, DhR, and OhR). PST is sensitive to clothing insulation as a function of clothing. OhR is more sensitive to clothing insulation during the day and to the metabolic rate at night. From these results, it appears that when exposed to high-temperature thermal environments in summer, wearing highly insulated clothing and getting enough rest (to lower the metabolic rate) can aid in preventing heat-related illnesses. Moreover, in the case of high-intensity harbor work, quantification of allowed working time (OhR) during heat waves is significant for human health sciences.

• Health Policy and Management
• /
• v.20 no.1
• /
• pp.87-102
• /
• 2010

The objective of this study were to examine the impact of medicaid coverage expansion policy aimed at improving access to primary care. The case-control study was conducted to compare preventable hospitalization(PH) rate in new medicaid recipients versus national health insurance(NHI) enrollees form 1996 to 2001. Rates of preventable hospitalization associated with ambulatory care sensitive conditions(ACSC) were calculated and standardized by age and sex. Multinomial logit regression model was used to control the confounding factors such as age, gender and charlson comorbidity index Annual PH rates in the new medicaid increased 1.64 times after medicaid expansion, with controling confounding factors. Meanwhile, annual PH rate in the NHI increased 1.68 times during the same period, with adjusting confounding factors. Current findings suggest that the new medicaid PH rate was less likely to rise than NHI PH rate after implementing medicaid expansion. This study is expected to provide policy-relevant evidence of medicaid expansion to include population with low income.

• Proceedings of the Korean Society for Technology of Plasticity Conference
• /
• 2008.10a
• /
• pp.130-133
• /
• 2008

The formability of DP steels can be affected by not only initial texture but also deformation texture evolved during plastic deformation. To investigate the evolution of deformation texture during deep drawing, deep drawing process for DP steels was carried out experimentally. A rate sensitive polycrystal model was used to predict texture evolution during deep drawing process. In order to evaluate the strain path during deep drawing, a steady state was assumed in the flange part of deep drawn cup. A rate sensitive polycrystal model successfully predicted the texture development in DP steels during deep drawing process. It was found that the final stable orientations were strongly dependent on the initial location in the blank.

• Journal of Pharmaceutical Investigation
• /
• v.37 no.3
• /
• pp.173-177
• /
• 2007

The purpose of this study was to investigate the effect of salt formation on the percutaneous absorption of meloxicam through hairless mouse skin from a pressure sensitive adhesive (PSA) matrix. In addition, the influences of enhancers on the permeation of meloxicam or meloxicam-ethanolamine (MX-EA) salts across the hairless mouse skin were evaluated using a flow-through diffusion cell system. The salt formation of meloxicam resulted in lower permeation rate than the parent drug. $Span^{(R)}$ 80 provided the highest enhancing effect for meloxicam and meloxicam monoethanolamine salt. The maximum amount of the drug that can be loaded without retarding permeation rate was different depending on the compound. No relationship was found between the fluxes of meloxicam or MX-EA salts from saturated solutions and those from PSA matrices containing the same enhancer.

• Journal of Pharmaceutical Investigation
• /
• v.33 no.2
• /
• pp.79-84
• /
• 2003

The effects of various pressure sensitive adhesives (PSA) and enhancers on the percutaneous absorption of tulobuterol were investigated. The permeation rate of tulobuterol through hairless mouse skin from various adhesives was evaluated using a flow-through diffusion cell system at $37^{\circ}C$. The permeability of tulobuterol was variable depending on the physicochemical property of the PSA. The permeation rate of tulobuterol from polyethylene oxide grafted acrylic adhesive matrix was higher than that from other PSA matrices. The flux of tulobuterol was $4.37{\pm}0.34\;{\mu}g/hr/cm^2$ from polyethylene oxide grafted acrylic adhesive matrix. When the effects of various enhancers on the percutaneous absorption of tulobuterol from grafted acrylic adhesive were evaluated, Plurol $oleique^{\circledR}$ showed higher flux than all other enhancers tested.

• KIISE Transactions on Computing Practices
• /
• v.21 no.11
• /
• pp.681-688
• /
• 2015

The k nearest neighbor (k-NN) graph construction is an important operation with many web-related applications, including collaborative filtering, similarity search, and many others in data mining and machine learning. Despite its many elegant properties, the brute force k-NN graph construction method has a computational complexity of $O(n^2)$, which is prohibitive for large scale data sets. Thus, (Key, Value)-based distributed framework, MapReduce, is gaining increasingly widespread use in Locality Sensitive Hashing which is efficient for high-dimension and sparse data. Based on the two-stage strategy, we engage the locality sensitive hashing technique to divide users into small subsets, and then calculate similarity between pairs in the small subsets using a brute force method on MapReduce. Specifically, generating a candidate group stage is important since brute-force calculation is performed in the following step. However, existing methods do not prevent large candidate groups. In this paper, we proposed an efficient algorithm for approximate k-NN graph construction by regrouping candidate groups. Experimental results show that our approach is more effective than existing methods in terms of graph accuracy and scan rate.