• KSII Transactions on Internet and Information Systems (TIIS)
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• 제12권11호
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• pp.5269-5286
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• 2018

Task scheduling is one of the key issues in improving system performance and optimizing resource management in cloud computing environment. In order to provide appropriate services for heterogeneous users, we propose a novel task scheduling strategy with service differentiation, in which the delay sensitive tasks are assigned to the rapid cloud with high-speed processing, whereas the fault sensitive tasks are assigned to the reliable cloud with service restoration. Considering that a user can receive service from either local SaaS (Software as a Service) servers or public IaaS (Infrastructure as a Service) cloud, we establish a hybrid queueing network based system model. With the assumption of Poisson arriving process, we analyze the system model in steady state. Moreover, we derive the performance measures in terms of average response time of the delay sensitive tasks and utilization of VMs (Virtual Machines) in reliable cloud. We provide experimental results to validate the proposed strategy and the system model. Furthermore, we investigate the Nash equilibrium behavior and the social optimization behavior of the delay sensitive tasks. Finally, we carry out an improved intelligent searching algorithm to obtain the optimal arrival rate of total tasks and present a pricing policy for the delay sensitive tasks.

• 미생물학회지
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• 제46권3호
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• pp.233-239
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• 2010

Bacillus subtilis에 존재하는 DEAD-box RNA helicase에 대한 유전자 상동성 검색을 통해 yqfR, yfmL, ydbR, deaD 의 4종류의 유전자를 확인하였고 이들 유전자 각각의 결손 돌연변이체를 제조하였다. 이들 돌연변이체들의 특성을 알아보기 위하여 LB 배양액을 사용하여 여러 온도에서의 생장 속도를 조사하였다. LB 배양액에서 $37^{\circ}C$의 생장 결과 ydbR 결손 균주가 다소 생장이 느려지나($T_d$=53 min) 다른(yqfR, yfmL, deaD) 결손 돌연변이체들은($T_d$=30-40 min) 결손이 없는 야생형 균주 CU1065와($T_d$=32 min) 유사하였다. 반면에 $22^{\circ}C$에서의 생장은 CU1065 ($T_d$=102 min)에 비해 yqfR ($T_d$=151 min), yfmL ($T_d$=214 min), ydbR ($T_d$=343 min) 결손 균주 순으로 생장속도가 느린 저온 민감성을 보인다. deaD의 $22^{\circ}C$에서의 생장 속도는 ($T_d$=109 min) CU1065와 ($T_d$=102 min) 매우 유사하여 저온 민감성을 보이지 않았다. 그리고 이들 유전자들의 이중, 삼중, 사중의 결손 균주들을 제조하였고, 여러 온도에서 ($42^{\circ}C$, $37^{\circ}C$, $22^{\circ}C$) LB 배양액을 사용하여 생장 속도를 측정 하였다. 다중 결손은 단일 결손보다 더 심한 저온 민감성을 보이며, 이중 결손의 경우, ydbR과 yfmL의 결손이 다른 조합의 결손보다 보다 큰 저온 민감성을 나타내었다 ($T_d$=984 min). 이러한 저온 민감성은 E. coli의 csdA 혹은 srmB 결손의 결과와 유사하며 리보솜 조립과 관련이 있는 생리적 기능으로 보인다.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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• pp.283.2-283.2
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• 2003

This study established a highly sensitive novel quantification method for detecting felodipine in human plasma using LC-MS/MS. The mobile phase used after degassing was composed of 1 mM ammonium acetate and acetonitrile (20:80, pH 6.0), with flow rate of 200 uL/min. One mL plasma were pipetted into glass tubes and spiked with 0.1 mL of internal standard solution. (omitted)

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 1998년도 추계종합학술대회 논문집
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• pp.75-78
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• 1998

In this paper, we propose a new cell discarding and scheduling scheme which reduce cell loss rate by measuring, in real time, the number of discarded cells in the queuing system with a different loss priority for each class of service such that each class of service meets its cell loss rate requirements and reduce average delay rate for the traffic that is sensitive in cell delay in output buffer of the ATM switch. Throughout the computer simulation, the existing scheduling scheme and proposed scheme are compared with respect to cell loss rate and average delay time.

• 한국환경과학회지
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• 제25권7호
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• pp.951-961
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• 2016

To prevent increasing instances of heat-related illnesses due to heat waves generated by climate change, a customized thermal environment index should be developed for outdoor workers. In this study, we conducted sensitivity analysis of the Masan harbor during a heat wave period (August 9th to 15th, 2013) using the MENEX model with metabolic rate and clothing-insulation data, in order to obtain realistic information about the thermal environment. This study shows that accurate input data are essential to gather information for thermophysiological indices (PST, DhR, and OhR). PST is sensitive to clothing insulation as a function of clothing. OhR is more sensitive to clothing insulation during the day and to the metabolic rate at night. From these results, it appears that when exposed to high-temperature thermal environments in summer, wearing highly insulated clothing and getting enough rest (to lower the metabolic rate) can aid in preventing heat-related illnesses. Moreover, in the case of high-intensity harbor work, quantification of allowed working time (OhR) during heat waves is significant for human health sciences.

• 보건행정학회지
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• 제20권1호
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• pp.87-102
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• 2010

The objective of this study were to examine the impact of medicaid coverage expansion policy aimed at improving access to primary care. The case-control study was conducted to compare preventable hospitalization(PH) rate in new medicaid recipients versus national health insurance(NHI) enrollees form 1996 to 2001. Rates of preventable hospitalization associated with ambulatory care sensitive conditions(ACSC) were calculated and standardized by age and sex. Multinomial logit regression model was used to control the confounding factors such as age, gender and charlson comorbidity index Annual PH rates in the new medicaid increased 1.64 times after medicaid expansion, with controling confounding factors. Meanwhile, annual PH rate in the NHI increased 1.68 times during the same period, with adjusting confounding factors. Current findings suggest that the new medicaid PH rate was less likely to rise than NHI PH rate after implementing medicaid expansion. This study is expected to provide policy-relevant evidence of medicaid expansion to include population with low income.

• 한국소성가공학회:학술대회논문집
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• 한국소성가공학회 2008년도 추계학술대회 논문집
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• pp.130-133
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• 2008

The formability of DP steels can be affected by not only initial texture but also deformation texture evolved during plastic deformation. To investigate the evolution of deformation texture during deep drawing, deep drawing process for DP steels was carried out experimentally. A rate sensitive polycrystal model was used to predict texture evolution during deep drawing process. In order to evaluate the strain path during deep drawing, a steady state was assumed in the flange part of deep drawn cup. A rate sensitive polycrystal model successfully predicted the texture development in DP steels during deep drawing process. It was found that the final stable orientations were strongly dependent on the initial location in the blank.

• Journal of Pharmaceutical Investigation
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• 제37권3호
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• pp.173-177
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• 2007

The purpose of this study was to investigate the effect of salt formation on the percutaneous absorption of meloxicam through hairless mouse skin from a pressure sensitive adhesive (PSA) matrix. In addition, the influences of enhancers on the permeation of meloxicam or meloxicam-ethanolamine (MX-EA) salts across the hairless mouse skin were evaluated using a flow-through diffusion cell system. The salt formation of meloxicam resulted in lower permeation rate than the parent drug. $Span^{(R)}$ 80 provided the highest enhancing effect for meloxicam and meloxicam monoethanolamine salt. The maximum amount of the drug that can be loaded without retarding permeation rate was different depending on the compound. No relationship was found between the fluxes of meloxicam or MX-EA salts from saturated solutions and those from PSA matrices containing the same enhancer.

• Journal of Pharmaceutical Investigation
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• 제33권2호
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• pp.79-84
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• 2003

The effects of various pressure sensitive adhesives (PSA) and enhancers on the percutaneous absorption of tulobuterol were investigated. The permeation rate of tulobuterol through hairless mouse skin from various adhesives was evaluated using a flow-through diffusion cell system at $37^{\circ}C$. The permeability of tulobuterol was variable depending on the physicochemical property of the PSA. The permeation rate of tulobuterol from polyethylene oxide grafted acrylic adhesive matrix was higher than that from other PSA matrices. The flux of tulobuterol was $4.37{\pm}0.34\;{\mu}g/hr/cm^2$ from polyethylene oxide grafted acrylic adhesive matrix. When the effects of various enhancers on the percutaneous absorption of tulobuterol from grafted acrylic adhesive were evaluated, Plurol $oleique^{\circledR}$ showed higher flux than all other enhancers tested.

• 정보과학회 컴퓨팅의 실제 논문지
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• 제21권11호
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• pp.681-688
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• 2015

k-Nearest Neighbor(k-NN)그래프는 모든 노드에 대한 k-NN 정보를 나타내는 데이터 구조로써, 협업 필터링, 유사도 탐색과 여러 정보검색 및 추천 시스템에서 k-NN그래프를 활용하고 있다. 이러한 장점에도 불구하고 brute-force방법의 k-NN그래프 생성 방법은 $O(n^2)$의 시간복잡도를 갖기 때문에 빅데이터 셋에 대해서는 처리가 곤란하다. 따라서, 고차원, 희소 데이터에 효율적인 Locality Sensitive Hashing 기법을 (key, value)기반의 분산환경인 MapReduce환경에서 사용하여 k-NN그래프를 생성하는 알고리즘이 연구되고 있다. Locality Sensitive Hashing 기법을 사용하여 사용자를 이웃후보 그룹으로 만들고 후보내의 쌍에 대해서만 brute-force하게 유사도를 계산하는 two-stage 방법을 MapReduce환경에서 사용하였다. 특히, 그래프 생성과정 중 유사도 계산하는 부분이 가장 많은 시간이 소요되므로 후보 그룹을 어떻게 만드는 것인지가 중요하다. 기존의 방법은 사이즈가 큰 후보그룹을 방지하는데 한계점이 있다. 본 논문에서는 효율적인 k-NN 그래프 생성을 위하여 사이즈가 큰 후보그룹을 재구성하는 알고리즘을 제시하였다. 실험을 통해 본 논문에서 제안한 알고리즘이 그래프의 정확성, Scan Rate측면에서 좋은 성능을 보임을 확인하였다.