• 대한약리학회지
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• 제8권2호
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• pp.63-69
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• 1972

The effects of omission of buffers from Krebs-Ringer medium on contractile activity, membrane potentials and ATP content of electrically stimulated isolated rat atria were investigated. 1) Contractile status: A rapid and marked depression of the contractile activity of atria occurred when buffer-free medium was substituted for the normal Krebs-Ringer medium. 2) Electrical status: The omission of buffers from medium did not alter the resting or action potential magnitudes of atria. However, the action potential duration was on initial increase followed by a decrease in the buffer-free medium. 3) ATP concentration: The omission of buffers from medium resulted in a marked decrease in the ATP levels of atria. It has been also found in the present study that bicarbonate buffer plays an important role for the maintenance of the contractility and ATP levels of the heart. The contractile depression by the omission of buffers was not directly associated with electrical alterations in resting or action potentials of the heart. In the absence of bicarbonate-buffer, glucose no longer plays to maintain the contractile activity and the ATP levels of rat atria.

• 대한미생물학회지
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• 제21권3호
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• pp.381-385
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• 1986

Twenty strains of penicillin(PC)-resistant Staphylococcus aureus ($MIC{\geqq}32U/ml$) were chosen randomly from recent isolates and submitted to the present experiment to see what effect the combined antibiotic action of moxalactam(MX) and fosfomycin(FM) would bring about on the cells, using MS-2 system. 1. The conventional agar dilution method and the rapid automatic MS-2 system were used in measuring the MICs of MX and FM against each strain and the comparison of the data obtained revealed no significant difference between the two methods in the titer and distribution of the MICs. 2. The automatic MS-2 system was, therefore, used alone in determining the combined growth inhibitory effect of MX and FM because of its more rapidness, and the obtained results were that most of the PC-resistant strains(16 out of 20, 80%) were synergistically inhibited by the two antibiotic combination while additive effect was observed in the remaining 4 strains(20%). 3. Thus, it is suggested that the growth of PC-resistant staphylococcal cells may be synergistically inhibited by MX and FM combination and the efficiency of two antibiotic action as well as MIC of single antibiotic may be more rapidly determined by the MS-2 system than by the conventional method.

• 한국의류산업학회지
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• 제24권6호
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• pp.686-693
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• 2022

The rapid development of the fashion industry in contemporary society has also caused various problems such as environmental pollution, material excess, and spiritual poverty. Accordingly, traditional Chinese Taoist aesthetics can solve the spiritual poverty that people are facing today, and the spiritual pursuit of returning to innocence. This study focuses on the works of first generation Chinese designer Ma Ke as an example to discuss the embodiment and application of Taoist aesthetics. The results are as follows: First, Ma Ke's works emphasize the value of handicraft through traditional handcrafting and natural fibers, which reflect the beauty of simplicity and the non-action of Taoist aesthetics. Second, the works acknowledge nature by using natural materials and retaining their original appearance, which embodies Taoist aesthetics of the beauty in non-action and living in harmony with nature. Third, the collections reflect a critical attitude toward the fashion industry and consumer culture by rethinking consumerism and advocating environmental protection, thus propagating the beauty in simplicity and the harmonious life with nature in Taoism aesthetics. In conclusion, Ma Ke's designs incorporating sustainability and handicraft exhibit the core features of Taoist aesthetics, including the beauty in simplicity, non-action, and living in harmony with nature while exploring the relationship between modernity and tradition, man and nature, and handicraft and fashion. This research can contribute to understanding Ma Ke's works in promoting critical thinking about the fashion industry through Taoist aesthetics.

• 벤처창업연구
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• 제11권3호
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• pp.199-208
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• 2016

본 연구는 요양보호사의 직무자율성에 대한 인식 확산 및 고령화가 급격히 증가되는 시점에서 요양보호사를 대상으로 직무자율성과 혁신행동의 관계를 규명하고자 하였다. 이에 서울지역에서 근무하는 요양보호사를 대상으로 직무자율성과 인구통계학적 특성 요인들이 혁신행동에 영향을 미치는 요인들을 분석하였다. 분석 결과 직무자율성, 작업스케줄, 의사결정, 방법론, 연령, 학력, 시설유형, 시설규모, 직급 등이 혁신행동에 통계적으로 유의미한 영향을 미치는 것으로 나타났다. 즉, 요양보호사는 조직 환경에서 직무에 대한 자율성이 많이 부여될수록, 조직풍토가 새로운 아이디어를 지양하는 분위기일수록 그리고 요양보호사에게 직무자율성이 많이 부여될수록 혁신행동에 긍정적인 영향을 미친다는 것을 알 수 있다. 이를 바탕으로 시설장은 요양보호사들이 보다 새로운 아이디어를 제시할 수 있는 조직풍토를 제공하는 한편, 요양보호사들의 직무자율성 향상을 위한 경영전략 및 개발이 요구되어진다.

• BMB Reports
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• 제47권8호
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• pp.417-423
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• 2014

MicroRNAs (miRNAs) are a large family of post-transcriptional regulators, which are 21-24 nt in length and play a role in a wide variety of biological processes in eukaryotes. The past few years have seen rapid progress in our understanding of miRNA biogenesis and the mechanism of action, which commonly entails a combination of target degradation and translational repression. The target degradation mediated by Argonaute-catalyzed endonucleolytic cleavage exerts a significant repressive effect on target mRNA expression, particularly during rapid developmental transitions. This review outlines the current understanding of the mechanistic aspects of this important process and discusses several different experimental approaches to identify miRNA cleavage targets.

• 한국식품영양과학회지
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• 제14권1호
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• pp.72-76
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• 1985

This studies were conducted in an attempt to investigate the effect of Oenanthe javanics extract on enzyme activities of liver and excretory action of bile juice in serum of carbon tetrachloride-intoxicated rabbits. Long-term oral administration of this extracts shows more rapid recuperation in GPT, total cholesterol, alkaline phosphatase, total bilirubin and BSP values than control groups. 750 mg/kg-administered group shortens rapidly the recovery time o·』 GPT, total cholesterol and BSP values than 250 mg/kg administered groups. But any difference was not observed in alkaline phosphatase, bilirubin among two groups. In histological studies the lager amount-administered groups exhibited more rapid recovery of liver cell enlargement, oedema, necrosis in carbon-tetrachloride treated rabbits.

• 대한인간공학회:학술대회논문집
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• 대한인간공학회 1995년도 춘계학술대회논문집
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• pp.43-43
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• 1995

차세대 원자력발전소 주제어실에서의 인간-기계 상호작용(Man-Machine Inter- action)에 대한 연구 및 인간공학 실험평가에 전문가시스템 기술의 응용에 관해 고찰 한다. 차세대 원전 주제어실에서의 인간-기계 상호작용에 대한 연구 및 실험평가는 차세대 주제어실이 CRT/VDU, 대형정보화면, 컴퓨터 시스템, 그리고 운전지원 소프트 웨어를 이용함으로서 운전원이 제어에서 의사결정 직무의 증가 특징을 가지게 되며, 이러한 환경에서 인간-기계 상호작용에 대한 연구 및 평가를 위한 전문가시스템의 주 요 응용은 rapid prototyping, 사용자 인터페이스 및 인간-기계 인터렉션의 지식기반 평가, 운전원 사고모형 개발, 실험데이타 해석 시스템 개발, 그리고 인터뷰 시스템 개 발 등을 들 수 있다. 차세대 주제어실에서의 인간-기계 상호작용 연구 및 인간공학 실험평가에 실시간 전문가시스템 쉘 G2의 실시간 시뮬레이션 기능, 객체지향 프로그 래밍 기능, rapid prototyping 기능, 그리고 추론기능을 중심으로 응용에 관해서 고찰 하였다.

• 전기전자학회논문지
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• 제3권1호
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• pp.109-117
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• 1999

본 논문에서는 급속 열처리 공정에서 필수적인 빠르고 정밀한 웨이퍼의 온도제어기법을 제안하였다. Bang- Bang/PID 제어기법은 빠른 온도상승률을 만족하고, 오버슈트와 정상상태 오차를 줄이도록 한다. 즉 초기에 허용 가능한 최대전력을 공급하는 일종의 Bang-Bang 방식의 제어를 하고, 설정온도와 출력에서 측정되는 온도와의 차이가 어느 정해진 범위보다 작을 때 PID 제어를 수행한다. 또한 PID 이득을 정하기 위해 ARX 모델로 식별된 플랜트에 Kappa-Tau 동조법이 사용되었다. 개발된 제어기는 실험용 RTP 장비에 적용하여 그 성능을 평가하였다.

• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2003년도 제10차 국제학술회의 및 추계정기 학술발표회
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• pp.46-46
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• 2003

An important function of pollen aperture is believed to be regulating the water balance of the pollen when subjected to changes in humidity (Shukla, et al. 1998). It has been reported that mature barley pollen rapidly swells upon hydration and pollen tube emerges in a few minutes of germination (Anthony and Harlan, 1920). Although, there could be other factors responsible for rapid hydration of pollen. However, K is widely known for its rapid action as an osmotic regulator (Heslop-Harrison and Heslop-Harrison, 1996). In the present study, changes in K distrbution were traced during different stages of pollen maturation in barley. The existence of K at the aperture area of matured pollen may possibly play other import physiological roles. For example, K is reported to be an essential constituent of pollen germination and even required in higher concentration for pollen tube growth(Fan et al., 2001). These results suggest that there could be a possible relationship between K, located at the aperture area and rapid uptake of water by pollen.

• 대한의용생체공학회:의공학회지
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• 제40권3호
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• pp.97-104
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• 2019

To examine different types of influenza diagnostic test kits automatically, automated rapid influenza diagnostic test method based on image recognition is proposed in this paper. First, the proposed methods classify a variety of the rapid influenza diagnostic test kit based on support vector machine that analyzes the kits' feature point. Then, to improve the accuracy of test, the proposed methods match the histogram of both the target image of influenza kit and the input image of influenza kit for minimizing the effect of environment factors, such as lighting and exposure variations. And, to minimize the effect from composition of the hand-helds devices, the proposed methods extract the feature point and match point-by-point between target image of influenza kit and input image of influenza kit. Experimental results of 124 experimental group show that the proposed methods significantly have effectiveness, which shows 90% accuracy in moderate antigen, for the preliminary examination of influenza, and provides the opportunity for taking action against influenza.