• Journal of the Korean Society of Marine Environment & Safety
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• v.21 no.2
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• pp.154-163
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• 2015

This study is based on deductions from analysis of historical changes in hydrographic surveys, the problems with the existing system in Korea and analysis of the literature, including foreign cases. Using these criteria, we created and administered a survey of marine professionals of Korea, and based on the results, established an order of priority for hydrographic surveys, as follows: changes in the seabed, quantities of marine traffic, existing performance data from hydrographic survey, consumer's demand, marine accidents, conservation of oceanic environment, and natural resources. The study also deduced, based on a survey of experts, the relative importance ranking of the major ports in South Korea and suggests policy implications and a priority decision model to conduct future hydrographic surveys in a more scientific and systematic way.

• 한국태양에너지학회:학술대회논문집
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• 2009.04a
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• pp.269-276
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• 2009

South Korea having military power within the $10^{th}$ in world ranking is the biggest single institution among public institutions in Korea and comprises force of over seven hundred thousand soldiers. However, outworn equipments and efficiency problem have issued. So, this study is to search the distribution state of new-renewable energy and to analyze application plan on the basis of interview with a official in charge in military. Analysis process is the first, classify surveyed military facilities into troops and the geographical factor. Second, classify a scale and type of facilities that new-renewable energy is supplied. Third, find consideration facts on the basis of interview with a official in charge. On the results of the survey, new-renewable energy applied to the military facility is photovoltaic, solar heat, wind power and geo-thermal energy. Also, divide military into the army, navy, air force and marine, visit 14 units and analyze the official's opinion. This study will deduce LCCA(Life cycle cost analysis) considered expenses for the installation and maintenance, and will be basic research that suggest an appropriate new-renewable energy model in military.

• Journal of Arbitration Studies
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• v.26 no.4
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• pp.83-109
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• 2016

Recently, China has brought many political, economical, and ideological changes in order to complete the "socialistic market economy." In terms of legal system, they make much effort to seek compatibility and stability of law and order. China recognizes that the breakdown of corruption, which is rampant in society, is an essential short-cut for national development. To realize anti-corruption reformation, it strengthens the supervision of relatives and close officials of high-ranking government officials. Recently, China has suffered from expanded trade disputes internationally and has also experienced severe management-labor conflicts domestically due to economic recession. From 2012 onward, civil lawsuit and other litigations have increased sharply. Also, they face severe conflicts in the land system. It is expected that many disputes arise due to speculation on rural housing. Meanwhile, Mongolia expands the size of trade with Korea in mutual cooperation since their diplomatic relation in 1990 by entering more than 20 treaties and agreements. As Mongolia has rich natural resources and Korea is equipped with advanced science and technology, the two countries have opportunities to develop mutually beneficial cooperative relations. Recently, the arbitration system has attracted attention instead of litigation as a means of dispute settlement in line with the expansion of trade between Korea and Mongolia. This study would be helpful to figure out desirable methods for dispute settlements in case of trade disputes among Korean companies that would advance into China and Mongolia.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.7 no.3
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• pp.133-141
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• 2012

Service and manufacturing companies' efforts are increasingly focused on utilizing services to satisfy customers' needs and survive in today's competitive market environment. The value of services depends mainly on service reliability that is identified by satisfaction derived from the relationship between customer and service provider. In this paper, we extend concepts from the failure modes and effects analysis of tangible systems to services. We use an event-based process model to facilitate service design and represent the relationships between functions and failures in a service. The objective of this research is to propose a method for evaluating service reliability based on service processes using fuzzy failure mode effects analysis (FMEA) and grey theory. We define the failure mode of service as interaction ways that can be failed in a service delivery process. The fuzzy set theory is used to characterize service reliability based on linguistic terms during FMEA. Grey theory is employed to determine the degree of relation and ranking among risk factors that are represented as potential failure causes. To demonstrate implementation of the proposed method, we use a case study involving a typical automotive service operation.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.9
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• pp.3817-3825
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• 2015

Background: The human protein methyl-transferase DOT1L catalyzes the methylation of histone H3 on lysine 79 (H3K79) at homeobox genes and is also involved in a number of significant processes ranging from gene expression to DNA-damage response and cell cycle progression. Inhibition of DOT1L activity by shRNA or small-molecule inhibitors has been established to prevent proliferation of various MLL-rearranged leukemia cells in vitro, establishing DOT1L an attractive therapeutic target for mixed lineage leukemia (MLL). Most of the drugs currently in use for the MLL treatment are reported to have low efficacy, hence this study focused on various natural compounds which exhibit minimal toxic effects and high efficacy for the target receptor. Materials and Methods: Structures of human protein methyl-transferase DOT1L and natural compound databases were downloaded from various sources. Virtual screening, molecular docking, dynamics simulation and drug likeness studies were performed for those natural compounds to evaluate and analyze their anti-cancer activity. Results: The top five screened compounds possessing good binding affinity were identified as potential high affinity inhibitors against DOT1L's active site. The top ranking molecule amongst the screened ligands had a Glide g-score of -10.940 kcal/mol and Glide e-model score of -86.011 with 5 hydrogen bonds and 12 hydrophobic contacts. This ligand's behaviour also showed consistency during the simulation of protein-ligand complex for 20000 ps, which is indicative of its stability in the receptor pocket. Conclusions: The ligand obtained out of this screening study can be considered as a potential inhibitor for DOT1L and further can be treated as a lead for the drug designing pipeline.

• Convergence Security Journal
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• v.15 no.4
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• pp.43-55
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• 2015

The effective cyber capability assessment methodology does not exist, it's difficult to check the current state of the our country's cyber capabilities and to establish cyber capability enhancement plan based on the result of assessment. The cyber capability assessment is necessary in order to determine the current level of the country, establish policy directions and provide the basis for effective budgeting. But assessment of national cyber capability is multi-criteria decision makink problem. In this paper develops an assessment model based on the AHP and TOPSIS. AHP is used to determine weight of the criteria and TOPSIS method is used to obtain final ranking. We also introduce the result of four major nations cyber capability assessment using the proposed methodology. The experiment used the virtual experimental data. And the result show that the proposed methodology can expand the number of criteria and alternatives for assessment and provide more sophisticated mathematical base for objective assessment comparing methodology using AHP only.

• Asian-Australasian Journal of Animal Sciences
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• v.15 no.9
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• pp.1371-1377
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• 2002

During a 5-yr period, 1994-1998, pre-weaning and weaning data were collected on 591 calves produced by mating either straightbred Jersey, straightbred Limousin or $F_1$ (Limousin${\times}$Jersey) bulls to mature purebred Jersey or Limousin cows. Traits recorded included birth and weaning weight, height, length, girth, fat depth and a measure of muscle (ratio of stifle to hip width expressed as a percentage). All traits were analyzed assuming a model with sire and dam random effects that included effects of year and date of birth, sex, breed and year${\times}$sex interaction. Main effects were generally significant with few exceptions. Direct genetic effects were large for weight, height, girth and muscle with a breed trend from purebred Jersey (small) to purebred Limousin (large). At weaning, the maternal effect of the Jersey dam was positive for weight (10.9${\pm}$4.9 kg), girth (3.7${\pm}$1.0 cm) and muscle (6.0${\pm}$0.9%). Heterosis was highly significant and positive only for fat depth (1.5${\pm}$0.2 mm) with the $F_1$ progeny being the fattest, followed by the backcrosses, then purebred Jersey and purebred Limousin. Also, significant (p<0.001) but negative heterosis was observed for weight, girth and muscle. The change in ranking for fat depth relative to other traits is a reflection of the large heterotic effects relative to direct effects on fat depth. Epistatic effects were not significant on any trait at birth or weaning. This study has indicated the possibility of exploiting the positive heterotic and maternal effects for fat depth and muscularity to meet specific meat quality and quantity demand by consumers.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.34 no.1
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• pp.1-10
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• 2008

Oral squamous cell carcinoma (OSCC) is the most frequent form of oral cancer and holds the eighth position in the cancer incidence ranking. OSCC patients are treated by classical therapeutic modalities consisting of surgery, radiotherapy, and/or chemotherapy. But OSCC still shows significant mortality rates. Thus, new therapeutic approaches have been investigated and the most promising one is naturally acquired agents with known anti-cancer effects. Genistein is a compound extracted from soy bean. Its anti-cancer effect on breast cancer is well established now and it is investigated whether it has similar effect on OSCC. It inhibited the growth and invasive-ness of OSCC cells in vitro, but these effects did not work in living animals in vivo. Catechin is a compound from green tea and its anti-cancer effect on OSCC is known better than other agents. Catechin showed its anti-cancer effect in vitro via induction of apoptosis, cell cycle arrest, inhibition of growth, and down-regulation of invasion/metastasis. These effects were confirmed in vivo with mouse model. Cordycepin is one of major pharmacologically important components in Cordyceps Militaris and may exert its anti-cancer effect as an adenosine receptor agonist. In recent study, it inhibited the proliferation of OSCC cells via A3 adenosine receptor. But because there is very scarce evidence on this effect, more researches are needed on this theme.

• Safety and Health at Work
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• v.9 no.2
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• pp.133-139
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• 2018

Background: Selecting priority occupational carcinogens is important for cancer prevention efforts; however, standardized selection methods are not available. The objective of this paper was to describe the methods used by CAREX Canada in 2015 to establish priorities for preventing occupational cancer, with a focus on exposure estimation and descriptive profiles. Methods: Four criteria were used in an expert assessment process to guide carcinogen prioritization: (1) the likelihood of presence and/or use in Canadian workplaces; (2) toxicity of the substance (strength of evidence for carcinogenicity and other health effects); (3) feasibility of producing a carcinogen profile and/or an occupational estimate; and (4) special interest from the public/scientific community. Carcinogens were ranked as high, medium or low priority based on specific conditions regarding these criteria, and stakeholder input was incorporated. Priorities were set separately for the creation of new carcinogen profiles and for new occupational exposure estimates. Results: Overall, 246 agents were reviewed for inclusion in the occupational priorities list. For carcinogen profile generation, 103 were prioritized (11 high, 33 medium, and 59 low priority), and 36 carcinogens were deemed priorities for occupational exposure estimation (13 high, 17 medium, and 6 low priority). Conclusion: Prioritizing and ranking occupational carcinogens is required for a variety of purposes, including research, resource allocation at different jurisdictional levels, calculations of occupational cancer burden, and planning of CAREX-type projects in different countries. This paper outlines how this process was achieved in Canada; this may provide a model for other countries and jurisdictions as a part of occupational cancer prevention efforts.

• Journal of Digital Convergence
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• v.14 no.11
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• pp.45-51
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• 2016

Although the problem of personal data leakage is reported to be serious, there has been no research that tries to excavate out that real cause of the leakage in scientific prospective. Although this topic is considered to be crucial, there have been no literatures relevant to the topic, and the reason for this limitation is that scientific approach to this problem was not feasible. In this respect, in this paper a model for such scientific analysis and a methodology of analysis have been devised. Results show that the degree of rigidity turns out be the determinant that vindicates the degree of leakage. The notion of data rigidity is revealed to be very strongly correlated to the number of hacking incidents in each country. The notion of resident data freedom was then deployed in this paper to determine the world-wide ranking for a slew of different countries. The United Kingdom and the Republic of Korea turned out to be the two extreme countries that lie in the spectrum of the scale, with UK the most flexible and ROK one of the most rigid.