• 제목/요약/키워드: randomized method

검색결과 900건 처리시간 0.027초

의학교육연구의 질을 향상시키기 위한 '연구보고의 표준' 의 활용 (Using of the "Consolidated Standards of Reporting Trials:CONSORT" to heighten quality of Medical Education study)

  • 유지수
    • 의학교육논단
    • /
    • 제10권2호
    • /
    • pp.25-44
    • /
    • 2008
  • Objectives: Through using of the strong research method like a Randomized Controlled Trial: RCT, we have to heighten quality of Medical Education study. I'd like to introduce "CONSORT", which stands for Consolidated Standards of Reporting Trials. Contents: Preventive Service Task Force(200l) in USA proposed Levels of evidence for enlarging evidence-based Practice: EBP. And the CONSORT was introduced, which encompasses various initiatives developed by the CONSORT Group to alleviate the problems arising from inadequate reporting of randomized controlled trials (RCTs). the CONSORT has 13 guides like these: 1. How participants were allocated to interventions 2. Scientific background and explanation of rationale 3. Eligibility criteria for participants. The settings and locations where the data were collected. 4. Precise details of the interventions intended for each group and how and when they were actually administered 5. Specific objectives and hypotheses 6. Clearly defined primary and secondary outcome measures, When applicable. any methods to enhance the quality of measurements (e.g., multiple observations, training of assessors) 7. How sample size was determined. When applicable, explanation of any interim analyses and stopping rules 8. Method used to generate the random allocation sequence, Details of any restriction [of randomization] 9. Method used to implement the random allocation sequence 10. Who generated the allocation sequence, who enrolled participants. and who assigned participants to their groups 11. Whether or not participants, those administering the interventions, and those assessing the outcomes were blinded to group assignment. If done, how the success of blinding was evaluated 12. Statistical methods used to compare groups for primary outcome(s), Methods for additional analyses, such as subgroup analyses and adjusted analyses 13. Flow of participants through each stage (a diagram is strongly recommended) Specifically, for each group report the numbers of participants randomly assigned. receiving intended treatment, completing the study protocol. and analyzed for the primary outcome. Results and Conclusion: Randomized Controlled Trial: RCT guided of CONSORT will contribute to do stronger evidence-based medical studies.

A SUCCESSIVE QUADRATIC PROGRAMMING ALGORITHM FOR SDP RELAXATION OF THE BINARY QUADRATIC PROGRAMMING

  • MU XUEWEN;LID SANYANG;ZHANG YALING
    • 대한수학회보
    • /
    • 제42권4호
    • /
    • pp.837-849
    • /
    • 2005
  • In this paper, we obtain a successive quadratic programming algorithm for solving the semidefinite programming (SDP) relaxation of the binary quadratic programming. Combining with a randomized method of Goemans and Williamson, it provides an efficient approximation for the binary quadratic programming. Furthermore, its convergence result is given. At last, We report some numerical examples to compare our method with the interior-point method on Maxcut problem.

확률화응답모형(RRM)을 활용한 성매매조사 분석 (Analysis of Prostitution Survey Using Randomized Response Model(RRM))

  • 손창균;주재진
    • 한국콘텐츠학회논문지
    • /
    • 제17권10호
    • /
    • pp.65-71
    • /
    • 2017
  • 통계조사 또는 실태조사는 '어떤 조사자가?', '어떤 목적으로?', 그리고 '어떻게?' 작성되었는가에 따라 왜곡의 가능성이 있는 것이 사실이다. 심지어는 통계결과는 '거짓말' 더 나아가서 범죄 또는 비행 등에 관한 통계는 '새빨간 거짓말'로 불리기도 한다. 범죄나 비행에 관한 통계를 신뢰하지 못하는 이유는 여러 가지를 들 수 있겠지만 그 중 대표적인 원인중의 하나가 숨은 범죄(Hidden Crime) 또는 형사사법기관에 보고되지 않는 범죄(Unreported Crime)가 존재한다는 것이다. 이러한 숨은 범죄문제를 보완하기 위해 피해자조사 또는 자기보고식 조사 등의 방법이 사용되고 있으나, 이 또한 범죄의 유형에 따라 과소보고 또는 과대보고의 문제가 있다. 범죄와 비행 그리고 일탈행동에 대한 조사는 매우 민감한 사항들이기 때문에, 조사대상자들은 심리적 부담을 가지게 된다. 이처럼 조사대상자들의 경험을 밝히는 것이 부담스러운 민감한 내용에 대해 진실한 답변을 유도할 수 있는 방법으로 통계학 분야에서 확률화응답모형(randomized response model)이 개발되어 사용되어왔다. 이 기법은 피해자조사 또는 자기보고식 조사의 문제점을 해결할 수 있는 매우 유용한 방법임에도 불구하고, 우리나라에서 범죄학 분야의 조사에서 사용된 경우는 매우 적다. 따라서 이 연구에서는 범죄학 분야연구에 있어 확률화응답모형의 적용가능성을 타진하기 위하여, 확률화응답모형을 활용하여 대학생들을 대상으로 성매매에 대한 내용을 실제로 측정해 보고, 확률화응답모형의 유용성을 확인해 보았다.

층화확률화 응답기법에 대한 동적 최적배분 (An Dynamic Optimal Allocation for the Stratified Randomized Response Technique)

  • 손창균;홍기학;이기성
    • Communications for Statistical Applications and Methods
    • /
    • 제16권4호
    • /
    • pp.595-603
    • /
    • 2009
  • 통상적으로 표준적인 최적배분은 층별 조사비용을 고려하여 표본을 배분한다. 만일 조사단위당 비용이 서로 다를 경우 보다 현실적인 배분방법을 고려할 필요가 있다. 즉, 개별 조사단위의 특성에 따라 이익비용비를 최대로 하는 단위를 먼저 표본으로 고려하는 동적배분을 고려하였다. 이러한 관점에서 층별 표본수를 배분하고, 배분된 표본규모에 따라 임의로 표본을 선정하는 방식인 표준적인 최적배분과는 차이가 있다. 이 논문은 약물오용, 낙태, 알콜중독 등과 같은 민감한 특성을 조사하는 층화확률화 응답기법에 대해 각 층별로 표본을 배분할 경우 최적 동적배분을 고려하여 보다 현실적인 문제를 해결하고자 하였으며, 수치적 예제를 통해 동적배분 방법의 효과성을 증명하였다.

확률화 블록 실험계획 모형에서 검정 통계량들의 검정력 분석 (The Analysis of power of the Test Statistics for the Randomized Block Design)

  • 배현웅;김제영
    • 한국국방경영분석학회지
    • /
    • 제27권2호
    • /
    • pp.124-133
    • /
    • 2001
  • The purpose of this study is investigate the differences among parametric and nonparametric test statistics for the tree alternative hypothesis in the randomized block design. As the results, it was found that there was no large differences among parametric and nonparametric test statistics in power when the block sizes were larger, and Hollander's statistic had better power than other nonparametric test statistics. It is recommended that Hollander's test statistic is more useful method when we have no information about the distribution of population.

  • PDF

한약제제 무작위 대조군 연구에서 대조군 설계의 문제점과 대안 (Problems and Countermeasures of Control Group Design in Randomized Controlled Trials of Herbal Medicine)

  • 윤영희;최인화
    • 한방안이비인후피부과학회지
    • /
    • 제21권2호
    • /
    • pp.94-101
    • /
    • 2008
  • Objectives : To discuss the types of control groups in randomized controlled trials (RCTs) of herbal medicine, and to provide suggestions for improving the design of control group in future clinical trials. Methods : We reviewed the 8 articles about clinical trial design of Chinese herbal preparation which were published from 2005 through 2008. We selected those articles from CNKI(中國知識基礎施設工程(http://www.cnki.net)). Results : It is necessary to have control group in randomized controlled trials(RCTs) of Korean herbal preparation. But there are problems in the selection of appropriate control group drug. This paper lists several problems about the choice of control drug and puts forward some proposals and countermeasures. There are problems such as ethics and manufacturing matching placebo and positive control herbal drug. Conclusion : To improve the quality of control group design, we introduce standard drug plus placebo drug method and add-on research for placebo control group design, double dummy technique, using negative control drug or composite control drug for active control group design.

  • PDF

산후신통의 한방 치료에 대한 무작위대조군연구에 관한 고찰 (Review of Randomized Controlled Trials on Korean Traditional Medicine Treatment for Postpartum Pain)

  • 노은지;최수지;김동일
    • 대한한방부인과학회지
    • /
    • 제33권2호
    • /
    • pp.90-111
    • /
    • 2020
  • Objectives: The purpose of this study was to analyze randomized controlled trials (RCTs) related to the effect and safety of Korean Traditional Medicine treatment for postpartum pain, and to suggest desirable future clinical research trend. Methods: Randomized controlled trials (RCTs) on postpartum pain were searched using domestic and foreign search engines to investigate the effect and safety of Korean Traditional Medicine on postpartum pain, and 12 studies were selected as a result. Results: There were 4 studies using Acupoint Therapy, 3 studies using Herbal Medicine, 3 studies using Using Acupoint Therapy and Herbal Medicine together, and 2 studies using Manipulative Therapy for postpartum pain. As control interventions, non-treatment, other Korean Traditional Medicine treatment, or Western medicine were used. All the studies reported a significant effect in experimental group compared to the control group, with no or minor side effects. Conclusions: Korean Traditional Medicine treatment showed effectiveness and safety for postpartum pain. In the future, it is necessary to eliminate the ambiguity of recruiting subjects and to study the most effective application method of Korean Traditional Medicine treatment for postpartum pain.

무작위 대조 이중맹검 시험을 통한 봉약침(蜂藥鍼)의 경항통(頸項痛)에 미치는 영향(影響) (A Randomized Controlled Double Blinding Study of Bee Venom Acupuncture Therapy on Sprain of C-spine)

  • 김경태;송호섭
    • Journal of Acupuncture Research
    • /
    • 제22권4호
    • /
    • pp.189-195
    • /
    • 2005
  • Objectives : This study was to evaluate the effectiveness of Bee Venom acupuncture therapy on sprain of C-spine by randomized controlled double blinding method. Methods : A randomized double blinding study of bee venom acupuncture therapy was conducted on sprain of C-spine. We divided sprain of C-spine patient into 2 groups: one group with both acupuncture and saline acupuncture therapy, and another group with both acupuncture and bee venom acupuncture therapy. To estimate the efficacy of treatment that applied for two groups, we used visual analog scale(VAS) and neck disability index(NDI). We compared the VAS and NDI score of two groups statistically. Results : STZ induced increase of serum creatinine, BUN and albumin secretion were lowered by AD-1 treatment.

  • PDF