• Title/Summary/Keyword: radio-resistant

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Radiation Sensitivity of Basidiospore and Mycelium in Pleurotus ostreatus

  • Lee, Young-Keun;Chang, Hwa-Hyoung
    • Nuclear Engineering and Technology
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    • v.31 no.3
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    • pp.287-293
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    • 1999
  • To assess the effects of gamma-ray (Co-60) on radiation sensitivity and genetic similarity of the basidiospore and mycelium in oyster mushroom, Pleurotus ostreatus, the D$_{10}$ values and RAPD patterns were analysed. Three strains were isolated from basidiospores (PO-Bl, -B2, and - B3 from 2 kGy irradiation group) and five strains from mycelia (PO-Ml, -M2 from 1 key, PO-M3 from 2 kGy, and PO-M4 and -M5 from 2+1 key irradiation group). The D$_{10}$ values of basidiospore and mycelium of P. Preurotus ostreatus were 1,250 Gy and 500 Gy, respectively. The growth rates of the eight strains on the five media were various and the activities of extracellular chitinases of them were generally higher than those of the control. By the gamma-ray radiation, 22-25% of genetic similarities were changed in the basidiospore strains and 23-36% of them in the mycelium strains. From these results, it seems that the basidiospore could be more radio-resistant than the mycelium of P. ostreatus and that the genetic similarity of the mycelium of P ostrentus could be changed easier than that of the basidiospore by the gamma-ray radiation.ion.

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Two Cystic Cavernous Angiomas after Radiotherapy for Atypical Meningioma in Adult Woman : Case Report and Literature Review

  • Ruggeri, Andrea Gennaro;Donnarumma, Pasquale;Pichierri, Angelo;Delfini, Roberto
    • Journal of Korean Neurosurgical Society
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    • v.55 no.1
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    • pp.40-42
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    • 2014
  • A correlation between radiation therapy and cavernoma has been suspected since 1994. Since then, only a few cases of radio-induced cavernomas have been reported in the literature (85 patients). Most of them were children, and the most frequent original tumour had been medulloblastoma. The authors report a case of two cystic cavernous angiomas after radiation therapy for atypical meningioma in adult woman. This is the first case of cavernous angioma after radiotherapy for low grade meningioma. A 39-year-old, Latin american woman was operated on for a frontal atypical meningioma with intradiploic component and adjuvant radiotherapy was delivered (6000 cGy local brain irradiation, fractionated over 6 weeks). Follow-up MR imaging showed no recurrences of the tumour and no other lesions. Ten years later, at the age of 49, she consulted for progressive drug-resistant headache. MR imaging revealed two new well defined areas of different signal intensity at the surface of each frontal pole. Both lesions were surgically removed; the histopathological diagnosis was cavernous angioma. This is the first case of cavernous angioma after radiation therapy for atypical meningioma : it confirms the development of these lesions after standard radiation therapy also in patients previously affected by non-malignant tumours.

Effects of Ionizing Radiation on Postharvest Fungal Pathogens

  • Jeong, Rae-Dong;Shin, Eun-Jung;Chu, Eun-Hee;Park, Hae-Jun
    • The Plant Pathology Journal
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    • v.31 no.2
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    • pp.176-180
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    • 2015
  • Postharvest diseases cause losses in a wide variety of crops around the world. Irradiation, a useful nonchemical approach, has been used as an alternative treatment for fungicide to control plant fungal pathogens. For a preliminary study, ionizing radiations (gamma, X-ray, or e-beam irradiation) were evaluated for their antifungal activity against Botrytis cinerea, Penicillium expansum, and Rhizopus stolonifer through mycelial growth, spore germination, and morphological analysis under various conditions. Different fungi exhibited different radiosensitivity. The inhibition of fungal growth showed in a dose-dependent manner. Three fungal pathogens have greater sensitivity to the e-beam treatment compared to gamma or X-ray irradiations. The inactivation of individual fungal-viability to different irradiations can be considered between 3-4 kGy for B. cinerea and 1-2 kGy for P. expansum and R. stolonifer based on the radiosensitive and radio-resistant species, respectively. These preliminary data will provide critical information to control postharvest diseases through radiation.

Non-cooperative interference radio localization with binary proximity sensors

  • Wu, Qihui;Yue, Liang;Wang, Long;Ding, Guoru
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.9 no.9
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    • pp.3432-3448
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    • 2015
  • Interference can cause serious problems in our daily life. Traditional ways in localizing a target can't work well when it comes to the source of interference for it may take an uncooperative or even resistant attitude towards localization. To tackle this issue, we take the BPSN (Binary Proximity Sensor Networks) and consider a passive way in this paper. No cooperation is needed and it is based on simple sensor node suitable for large-scale deployment. By dividing the sensing field into different patches, when enough patches are formed, good localization accuracy can be achieved with high resolution. Then we analyze the relationship between sensing radius and localization error, we find that in a finite region where edge effect can't be ignored, the trend between sensing radius and localization error is not always consistent. Through theoretical analysis and simulation, we explore to determine the best sensing radius to achieve high localization accuracy.

Improvement of Oxidation-resisting Characteristic for SOFC Interconnect Material by Use of Thin Film Coating (박막 코팅을 이용한 SOFC 분리판 재료의 내산화성 향상)

  • Lee, Chang-Bo;Bae, Joong-Myeon
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.30 no.12 s.255
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    • pp.1211-1217
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    • 2006
  • This study is focused on oxidation prevention of STS430, which is generally used as solid oxide fuel cell(SOFC) interconnect at intermediate operating temperatures with oxidation-proof coatings. Inconel, $La_{0.6}Sr_{0.4}CoO_3(LSCo)$ and $La_{0.6}Sr_{0.4}CoO_3(LSCr)$ were chosen as coating materials. Using a radio frequency magnetron sputtering method, each target material was deposited as thin film on STS430 and was analyzed to find out favorable conditions. In this study, LSCr-coated STS430 can reduce electrical resistance to 1/3 level, compared with uncoated STS430. Also, long-term durability test at $700^{\circ}C$ for 1000 hours tells that LSCr thin layer performs an important role to prohibit serious degradations. Superior oxidation-resistant characteristic of LSCr-coated STS430 is attributed to the inhibition of spinel structure formation such as $MnCr_2O_4$.

Application of ultra-high-temperature ceramics to oxidation-resistant and anti-ablation coatings for carbon-carbon composite (탄소-탄소 복합재의 내삭마 내산화 코팅을 위한 초고온 세라믹스의 적용)

  • Kim, Hyun-Mi;Choi, Sung-Churl;Cho, Nam Choon;Lee, Hyung Ik;Choi, Kyoon
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.29 no.6
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    • pp.283-293
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    • 2019
  • As applications in extreme environments such as aerospace, high-energy plasma and radio-active circumstances increases, the demand for materials that require higher melting points, higher mechanical strength and improved thermal conductivity continues to increase. Accordingly, in order to improve the oxidation/abrasion resistance of the carbon-carbon composite, which is a typical heat-resistant material, a method of using ultra high temperature ceramics was reviewed. The advantages and disadvantages of CVD coating, pack cementation and thermal plasma spraying, the simplest methods for synthesizing ultra-high temperature ceramics, were compared. As a method for applying the CVD coating method to C/C composites with complex shapes, the possibility of using thermodynamic calculation and CFD simulation was proposed. In addition, as a result of comparing the oxidation resistance of the TaC/SiC bi-layer coating and TaC/SiC multilayer coating produced by this method, the more excellent oxidation resistance of the multilayer coating on C/C was confirmed.

Membrane Protein Alterations Associated with Anticancer Drug Resistance in Mouse Lymphoblastic Leukemia L1210 Cells (항암제에 내성인 생쥐의 백혈병세포 L1210의 세포막 단백질의 변환)

  • Kim, Seong-Yong;Son, Sung-Kweon;Kim, Jae-Ryong;Kim, Jung-Hye
    • Journal of Yeungnam Medical Science
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    • v.10 no.2
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    • pp.432-444
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    • 1993
  • Multidrug resistance(MDR) phenotype is frequently observed in animal and human cancer cell lines selected for in vitro resistance to a single chemotherapeutic agent. It is characterized by the diminished drug accumulation and is related to the drug efflux mechanism in resistant cells. In the present study, adriamycin resistant cells(L1210-$AdR_6$ : $10^{-6}M$ adriamycin, $-AdR_5$ : $10^{-5}M$) and vincristine resistant cells (L1210-$VcR_7$ : $10^{-7}M$ vincristine, $-VcR_6$ : $10^{-6}M$) were produced from mouse lymphoblastic leukemia cell line L1210. Growth profiles of survived cells were observed for 5 days with MTT(thiazolyl blue) assay and resistance was compared with $IC_{50}$(drug concentration of 50% survival reduction in absorbance). Resistant cells proliferated more slowly than sensitive cell. Doubling times were 29.7hr in L1210, 68.7hr in L1210-$AdR_5$ and 58.2hr in $-VcR_6$. MDRs expressed as resistance factor were as follows, L1210-$AdR_5$ was 76.4 times for vincristine, L1210-$VcR_6$ was 96.4 times for adriamycin. The cell membrane proteins with three different M.W. were recognized to be related resistance, 220, 158, and 88 kd in L1210-$AdR_5$, 158, 140 and 88 kd in L1210-$VcR_6$ by SDS-PAG electrophoresis. Cell surface membrane proteins were identified by radio-iodination and autoradiogram, their molecular weights were 158, 72.8, and 42.4 Kd in L1210-$VcR_6$.

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Nationalism and Globalization Tendency in Sport Emotion of Korean : Focusing on 2016 Brazil Olympic Games (한국인의 스포츠 감정에 내재된 민족주의와 세계화 성향 : 2016년 브라질 하계 올림픽을 중심으로)

  • Lee, Jong-Kil;Lee, Kong-Joo;Yang, Jae-Sik
    • Journal of Digital Convergence
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    • v.16 no.8
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    • pp.341-349
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    • 2018
  • This study aimed to investigate the tendency of nationalism and globalization of Korean by analyzing their emotions in sport phase. The SNS comments of newspaper articles on 2016 Brazil Olympics were selected and used to analyze types of nationalism with its emotional texts. The results were as followings; First, the words which showed nationalistic tendency represented each sport phase. Second, Korean showed strong resistant nationalism when their historical background was stimulated by the situation. Third, the most dominant type of Korean's nationalism in sport emotion was the closed. This study could be valued with the empirical approach on the sport emotion and nationalism tendency of Korean.

BLOOD VISCOSITY CHANGE IN ORAL SQUAMOUS CELL CARCINOMA XENOTRANSPLANTED NUDE MICE (구강편평세포암종 이식 누드마우스에서의 혈액 점도 변화)

  • Myoung, Hoon;Lee, Jong-Ho;Choung, Pill-Hoon;Kim, Myung-Jin
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.30 no.2
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    • pp.81-84
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    • 2004
  • It is well known that malignant tumor have hypoxic cell fraction, which is radio resistant and is one of the most important cause of local recurrence after radiotherapy. One of the causes of hypoxia in tumor is blood flow decrease due to increase in blood flow resistance and one of the causes of increased blood flow resistance could be attributed to the increase in blood viscosity. For the evaluation of the change of blood viscosity in oral cancer, experiments were carried out to test the change of blood viscosity among the normal control and xenografted oral cancer nude mice. Relative viscosity measured against distilled water was $3.30{\pm}0.14$ for normal control, and $3.67{\pm}0.62$ for tumor bearing mice at the first time of blood sampling in experimental period ($100mm^3$ $200mm^3$). There was no statistically significant difference between the control group and experimental group (p>0.05). However, as the tumor grew, significant difference of blood viscosity was detected at the third time of blood sampling (control group:$3.37{\pm}0.59$, and experimental group: $4.31{\pm}0.41\;300mm^3$

CHANGE OF BLOOD VISCOSITY AND DEFORMABILITY IN ORAL SQUAMOUS CELL CARCINOMA PATIENTS (구강편평세포암종 환자에서의 혈액 점도와 혈액 변형성 변화에 대한 연구)

  • Yun, Pil-Young;Myoung, Hoon;Lee, Jong-Ho;Choung, Pill-Hoon;Kim, Myung-Jin
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.30 no.3
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    • pp.181-185
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    • 2004
  • Malignant tumor have hypoxic cell fraction, which makes radio-resistant and hypoxia in tumor is a result from the blood flow decrease caused by increase in blood flow resistance. Blood viscosity increase is major factor of increased blood flow resistance and it could be attributed to the decrease in blood deformability index. For the evaluation of the change of blood viscosity and blood deformability in oral squamous cell carcinoma, we perform the test of the change of those factors between the normal control group and oral squamous cell carcinoma cell patient group. Relative viscosity measured against distilled water was $5.25{\pm}0.14$ for normal control group, and $5.78{\pm}0.26$ for the SCC patient group and there was statistical significance between the groups. However, there was no significant difference between the groups in blood viscosity between the groups by tumor size (T1+T2 vs T3+T4). Also, there was no significant difference between the normal control group and SCC patient group in blood deformability index and between the groups by tumor size (T1+T2 vs T3+T4). Increase in blood viscosity was confirmed with this study and it can be postulated that modification blood viscosity might contribute to decrease of hypoxia fraction in oral squamous cell carcinoma, thus improve the effect of radiotherapy and it can be assumed that the main factor of blood viscosity increase is not decrease of blood deformability in oral squamous cell carcinoma.