• Applied Chemistry for Engineering
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• v.7 no.6
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• pp.1043-1052
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• 1996

Supercritical fluid chromatographic method was recommended as an alternative separation method of fatty acids of the conventional method such as distillation or extraction. Although diffusion characteristics are varied by the carbon numbers and the degree of unsaturation of fatty acids, the quantitative data were so rare that the commercialization of supercritical fluid chromatographic method has been hindered. In this study, diffusion coefficients of fatty acids which are differently unsaturated are measured by CPB method in the range of 308.15K to 328.15K and 13MPa to 17MPa in supercritical carbon dioxide. A decrease in the binary diffusion coefficient was observed with an increase in temperature and pressure. Also, the decrease in the binary diffusion coefficient with increasing fluid density and viscosity. Wilke-Chang equation, Funazukuri empirical equation, and Matthews-Akgerman equation are used to correlate the experimental diffusion coefficients of fatty acids in supercritical carbon dioxide. Among the various theoretical equations, Matthews-Akgerman equation based on RHS theory was suggested as a more successful correlation model with experimental data.

• Journal of Food Hygiene and Safety
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• v.33 no.5
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• pp.354-360
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• 2018

This study presents a method validation for extraction and quantitative analysis of trichothecene mycotoxins in nuts based on quick, easy, cheap, effective, rugged, and safe (QuEChERS) approach for extraction and enhanced matrix removal (EMR)-lipid-disperive-SPE (d-SPE) cleanup method, with detection and quantification by high-performance liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) in positive- and negative-ion modes. Linearity, precision, and accuracy were validated for LC-MS/MS methods. Results obtained with LC-MS/MS were linear, with correlation coefficient ($R^2$) of 0.998. Limits of detection and quantification for mycotoxins were $0.41-3.57{\mu}g/kg$ and $1.23-10.82{\mu}g/kg$, respectively. Intra- and inter-day precisions (RSD, %) were 0.40-8.44% and 1.93-12.46%, respectively. Results indicated to be rapidly and accurately identifying trichothecene mycotoxins and may be used as a suitable safety management method for nuts and nuts related commodities.

• The Journal of Korean Medicine
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• v.33 no.3
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• pp.1-9
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• 2012

Objectives: This research was aimed 1) to find out various subjective symptoms cancer patients had, 2) to find out the quantitative difference of symptoms occurring according to the area of cancer, current treatment methods, and relapse of the cancer and 3) to analyze the relationship between the occurrence of symptoms. Methods: This study was a survey about the various subjective symptoms cancer patients had. The subjects were 48 cancer patients in a double-blinded randomized controlled trial about the effectiveness of Korean Red Ginseng (KRG) treatments. Surveys were examined before Korean Red Ginseng (KRG) treatments. The questionnaire consisted of demographic research, patient history and accompanying symptoms. The symptoms part consisted of 4 questions on general symptoms (vertigo, hot flush, rash, insomnia), 2 questions on digestion symptoms (anorexia, dyspepsia), 2 questions on excretions (diarrhea, constipation), and 5 questions on symptoms in different body parts (headache, dryness of lips, chest pain, aphthous ulcer, nose bleeding). The questionnaire was used to research presence of symptoms and relationships between the occurrence of symptoms. Results: A total of 48 patients took part in this survey. Dizziness was the most frequent subjective symptom patients had (64.58%), followed by dry mouth (43.75%), headache (43.75%), insomnia (41.67%), anorexia (37.5%) and chest discomfort (37.5%). The presence of these subjective symptoms was partially related to the patient's history details - type of cancer, method of cancer treatment (chemotherapy, radiotherapy), termination of treatment, presence of pain, fatigue and recurrence, etc. Factor analysis was conducted to analyze the relationship between the occurrence of symptoms. It suggested 5 factors as a result, but there was a limitation that only a low level of correlation was shown among them. Conclusions: We were able to analyze the occurrences and the relationships among them for accompanying subjective symptoms in cancer patients. However the results of the study are limited in that only 48 patients participated. The symptoms in cancer patients showed a tendency for clustering, occurring simultaneously or continuously rather than occurring alone. The study of these symptom clusters is worth further study, for it is similar to the Symptom Differentiation System in Traditional Korean Medicine. For effective approach to the treatment of cancer in Traditional Korean Medicine, further research on the Korean traditional view of cancer patients should be done based on this research, regarding various symptoms and those relationships on a larger scale.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.6 no.1_2
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• pp.58-64
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• 1973

Changes in stock size of the Pacific saury, Cololabis saira, were studied on the basis of fishery statistics compiled from 1964 to 1972 and body size composition of the fish collected from 1968 to 1972. During the period from 1964 to 1972 there was a direct correlation between the stocks of fall (september-february of the following year) and spring (March-August) season. The sizes of stocks in both seasons showed a three-year cyclic change, and the mode of stock in the fall always proceeded one year that in the spring. Exceedingly high fishing effort was observed in the spring as well as the fall of 1967. But very low fishing effort was noticed in the spring of 1969. In spring a large stock size has a high proportion of large sized group. On the other hand, in fall a large stock size tends to have a high proportion of medium sized group instead. When the medium sized group outnumbers the large sized group, stock size becomes larger. In contrast, it tends to be smaller when the large sized group exceeds the medium sized group. The patterns of distribution centroid seems to be related to the amount of fish landings. Northward moving trend of the centroid was accompanied by a large amount of landing, while westward (or north-westward) moving trend was followed by a poor landing of the fish.

• The Journal of the Korea Contents Association
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• v.15 no.11
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• pp.10-17
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• 2015

Emotional computer that you want to study in a regular number change is the continuing sensitivity. Emotional Computing manner the sensibilities numbered and emotions were running through the trees. Emotional assessment of emotional sensibility computing was used as the coordinates of the key effects of the James A. Russell (Core Affect). Emotional tree runs purpose was to verify the correlation of sensitivity and emotion computing tree. Emotional tree attributes experiment color, brightness, saturation was configured with. When 50% brightness increase, about pleasure (X-axis) has increased by 10.49 points. Brightness 50%, GREEN 50% increase in the degree of pleasure (X-axis) of 10.49 points, tone (Y axis) has increased by 15.85 points. Brightness 50%, GREEN 50% increase in the degree of pleasure (X-axis) of 10.49 points, tone (Y axis) has increased by 15.85 points. Brightness 50% of the free-extent (X-axis), BLUE 50% when the tone (Y axis), pleasure extent (X-axis) of 10.49 points, tone (Y axis) as much as 14.65 points sensibilities have changed. When representatives emotions size changes have increased 50% brightness, color RED 50%, increased 5.4% Emotional excitement, emotion depressed declined -4.2%. 50% brightness, color GREEN 50% increase in emotional excitement had increased to 8.6%, declined by -5.5% this melancholy sensibility. Representative emotion and emotional changes increase or decrease the size of the emotional attributes were analyzed by quantitative methods. After the happy emotions number is needed to study more similar to the human emotion through the execution of the video image emotion emotional tree computing.

• Journal of Radiation Protection and Research
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• v.38 no.1
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• pp.29-36
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• 2013

The aim of this study was to determine the correlation between exposure index (EI) and dose factors related to radiation dose optimization in digital radiography (DR) system. Two phantoms with built-in regional test object for quantitative assessment of images were used to produce image signals that acquired in chest radiography background. EI and entrane surface dose (ESD) increased proportionally with rise of radiation dose (kVp, mAs) in both DR and CR systems. Especially, DR detector was effective to form good contrast and hence, reached easily to improvement of image quality with minimal dose changes. It made operators possible to expect the accuracy of EI values deeply related to absorbed dose of the detector. The evaluation of images was obtained specially employed calculation of noise to signal ratio (NSR) and contrast to noise ratio (CNR). These measurements were performed for how exposure factors affect image quality. NSR was inversely proportional to kVp and mAs and low NSR represented high signal detection efficiency. Consequently, EI values was the measure of the amount of exposure received by the image receptor and it was proportional to exposure factors. Therefore the EI in a recommended range from manufacturer can offer optimal image quality. Also, continuous monitoring of EI values in the digital radiography can reduce the unnecessary patient dose and help the quality control of the system.

• Sleep Medicine and Psychophysiology
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• v.3 no.1
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• pp.47-55
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• 1996

Narcolepsy is characterized by sleep attack with excessive daytime sleepiness(EDS), cataplexy, sleep paralysis, and hypnagogic hallucination. Paradoxically, narcoleptics tend to complain of frequent arousals and shallow sleep during the night time despite their excessive sleepiness. However, nocturnal sleep fragmentation in narcoleptics is relatively ignored in treatment strategies, compared with sleep attack/EDS and cataplexy. In our paper, we attempted to investigate further on the poor nocturnal sleep in narcoleptics and to discuss possible treatment interventions. Out of consecutively seen patients at Seoul National University Sleep Disorders Clinic and Division of Sleep Studies, we recruited 57 patients, clinically assessed as having sleep attack and/or EDS. Nocturnal polysomnography and multiple sleep latency test(MSLT) were done in each of the subjects. We selected 19 subjects finally diagnosed as narcolepsy(mean age $26.0{\pm}18.3$ years, 16 men and 3 women) for this study, depending on the nocturnal polysomnographic and MSLT findings as well as clinical history and symptomatology. Any subject co-morbid with other hypersomnic sleep disorders such as sleep apnea or periodic limb movements during sleep was excluded. Sleep staging was done using Rechtschaffen and Kales criteria. Sleep parameters were calculated using PSDENT program(Stanford Sleep Clinic, version 1.2) and were compared with the age-matched normal values provided in the program. In narcoleptics, compared with the normal controls, total wake time was found to be significantly increased with significantly decreased sleep efficiency(p<.01, p<.05, respectively), despite no difference of sleep period time and total sleep time between the two groups. Stage 2 sleep%(p<.05), slow wave sleep%(p<.05), and REM sleep%(p<.01) were found to be significantly decreased in narcoleptics compared with normal controls, accompanied by the significant increase of stage 1 sleep%(p<.01). Age showed negative correlation with slow wave sleep%(p<.05). The findings in the present study indicate significant fragmentation of nocturnal sleep in narcoleptics. Reduction of REM sleep% and the total number of REM sleep periods suggests the disturbance of nocturnal REM sleep distribution in narcoleptics. No significant correlations between nocturnal polysomnographic and MSLT variables in narcoleptics suggest that nocturnal sleep disturbance in narcoleptics may be dealt with, in itself, in diagnosing and managing narcolepsy. With the objective demonstration of qualitative and quantitative characteristics of nocturnal and daytime sleep in narcoleptics, we suggest that more attention be paid to the nocturnal sleep fragmentation in narcoleptics and that appropriate treatment interventions such as active drug therapy and/or circadian rhythm-oriented sleep hygiene education be applied as needed.

• Korean Journal of Plant Resources
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• v.26 no.4
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• pp.491-502
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• 2013

Persimmon (Diospyros kaki Thunb) fruit is one of the most important fruit and have been cultivated from ancient times in Korea. In this study, we found 16 EST-SSR markers that contained one or more EST-SSR sites from 246 cDNA sequences. The developing of EST-SSR marker analysis from 42 persimmon cultivars was compared by genetic relationships and morphological relationships using 6 qualitative traits (fruit related 6 traits) and 19 quantitative traits (flower related 19 traits). In this study, 25 primer sets were tested to identify PCR polymorphism and 14 potential EST-SSR primer pairs were selected. The result of morphological relationship EST-SSR marker analysis showed that the coefficient 0.02 was difficult to categorize in several groups. And then, coefficient 0.77 of genetic relationship showed that the group was classified as four groups. The result of correlation distance between genetic relationship and morphological relationship were investigated was low significance (-0.03). Our results also provided an optimized method for improvement of breeding efficiency and introduce of superior character at persimmon cultivars using EST-SSR markers which was useful for further investigation.

• The Journal of the Petrological Society of Korea
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• v.24 no.3
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• pp.209-231
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• 2015

In granite quarry, stones are generally quarried along easily separating planes called as 'rock cleavage'. Because orientation and characteristics of the rock cleavage are directly involved with easy quarrying, it is the most important factor on selecting a direction of digging. Using AMS (anisotropy of magnetic susceptibility), we attempt to interpret rock fabrics in Geochang Granite Stone (JS, SD, AR, GD, BW, MD quarry) and discuss about determination of rock cleavages and correlation between the rock fabrics and cleavages. Based on mean susceptibility, thermo-susceptibility curves, and hysteresis parameters, Ti-poor MD and/or PSD magnetites are the main contributor to AMS of the granite stones. The systematic magnetic foliations with sub-vertical dip angle are developed in the whole granite quarries. In most of the granite quarries, the magnetic foliations are significantly consistent with grain plane. In the BW quarry, which has higher $P_J$ values than the others, the magnetic foliations coincide exceptionally with rift plane. These results suggest that rock cleavages in granite stone are related to rock fabrics meaning shape and spatial arrangement of crystals. Magnetic fabrics analysis using AMS method, therefore, can be a quantitative and effective tool for determination of rock cleavages in granite quarry.

• Journal of Veterinary Clinics
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• v.22 no.2
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• pp.79-83
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• 2005

Six dogs including 4 dogs living in different geographic locations of Kangwon province and 2 client-owned dogs were used to determine the periodicity of microfilariae of D. immitis using a trigonometric model. The calculated periodicity index was ranged from 25.6 to $95.5\%$ with mean of $57.6\%$, and the estimated hour of peak was approximately 21:00 hrs (range, 20:04-21:29 hrs) and minimum counts at 09:00 hrs (range, 08:04 - 09:29 hrs). Correlation coefficient between the observed and the expected count from the model varies depending on dogs, ranging from 6.4 to $49.2\%$. Based on this study, the periodicity of microfilariae of D. immitis was considered as nocturnally sub-periodic for all dogs employed. This result is in consistent with previous report in peak hour but different in minimal hour, indicating that further studies on the periodicity need to be performed to better understanding the dynamics of the periodicity and to help practitioners in the choice of the time for examination of the dogs.