• 한국정밀공학회:학술대회논문집
• /
• 한국정밀공학회 2004년도 추계학술대회 논문집
• /
• pp.29-33
• /
• 2004

This paper presents ESPI system for the measurement of thermal expansion coefficient of STS430 up to 1,000$^{\circ}C$. Existing methods, strain gauge and moire have the limitation of contact to object and do not supply the coefficient up to 800$^{\circ}C$. There needs to measure the data up to 800$^{\circ}C$, because heat resistant materials have high melting temperature up to 1,000$^{\circ}C$. In previous studies related to thermal strain analysis, the quantitative results are not reported by ESPI at high temperature, yet. In-plane ESPI and vacuum chamber for the reduction of air turbulence and oxidation are designed for the measurement of the coefficient up to 1,000$^{\circ}C$and speckle correlation fringe pattern images are processed by commercial image filtering tool-smoothing, thinning and enhancement- to obtain quantitative results, which is compared with references data. The comparison shows two data are agreed within 4.1％ blow 600$^{\circ}C$ however, there is some difference up to 600$^{\circ}C$. Also, the incremental ratio of the coefficient is changed up to 800$^{\circ}C$. The reason is the phase transformation of STS430 probably begins at 800$^{\circ}C$.

• 한국정밀공학회지
• /
• 제21권11호
• /
• pp.69-74
• /
• 2004

This paper presents ESPI system for the measurement of thermal expansion coefficient of STS430 up to 1,00$0^{\circ}C$ . Existing methods, strain gauge and moire have the limitation of contact to object and do not supply the coefficient up to 80$0^{\circ}C$ . There needs to measure the data up to 80$0^{\circ}C$, because heat resistant materials have high melting temperature up to 1,000'E In previous studies related to thermal strain analysis, the quantitative results have not reported by ESPI at high temperature, yet. In-plane ESPI and vacuum chamber for the reduction of air turbulence and oxidation are designed for the measurement of the coefficient up to 1,00$0^{\circ}C$ and speckle correlation fringe pattern images are processed by commercial image filtering tool-smoothing, thinning and enhancement- to obtain quantitative results, which is compared with references data. The comparison shows two data are agreed within 4.1% blow $600^{\circ}C$ however, there is some difference up to $600^{\circ}C$. Also, the incremental ratio of the coefficient is changed up to 80$0^{\circ}C$ . The reason is the phase transformation of STS430 probably begins at 80$0^{\circ}C$

• Korean Chemical Engineering Research
• /
• 제58권2호
• /
• pp.286-292
• /
• 2020

본 연구에서는 별도의 이미지 분석 장비를 사용하지 않고 정량적으로 알부민의 농도를 측정할 수 있는 회전각도를 이용한 3차원 종이 칩(3D-PADs)를 제시한다. 변색된 구간의 회전각도를 측정하는 간단한 방법으로 검출을 시연하였다. 3D-PADs는 왁스 프린터를 이용한 인쇄와 라미네이팅 과정을 거쳐 빠르게 제작할 수 있다. 3D-PADs는 샘플의 알부민을 검출하기 위하여 citrate buffer와 tetrabromophenol blue를 흡수시켰다. 3D-PAD의 흡수패드에 샘플 용액을 흡수시키면, 샘플 용액은 형성된 유로를 통하여 수직 및 수평 흐름을 통해 분석 구간으로 흐른다. 변색된 구간의 회전각도는 특정한 알부민의 농도를 나타내며, 알부민 측정의 신뢰할 수 있는 값임을 확인할 수 있었다.

• The Korean Journal of Physiology and Pharmacology
• /
• 제19권4호
• /
• pp.373-382
• /
• 2015

Fura-2 analogs are ratiometric fluoroprobes that are widely used for the quantitative measurement of [$Ca^{2+}$]. However, the dye usage is intrinsically limited, as the dyes require ultraviolet (UV) excitation, which can also generate great interference, mainly from nicotinamide adenine dinucleotide (NADH) autofluorescence. Specifically, this limitation causes serious problems for the quantitative measurement of mitochondrial [$Ca^{2+}$], as no available ratiometric dyes are excited in the visible range. Thus, NADH interference cannot be avoided during quantitative measurement of [$Ca^{2+}$] because the majority of NADH is located in the mitochondria. The emission intensity ratio of two different excitation wavelengths must be constant when the fluorescent dye concentration is the same. In accordance with this principle, we developed a novel online method that corrected NADH and Fura-2-FF interference. We simultaneously measured multiple parameters, including NADH, [$Ca^{2+}$], and pH/mitochondrial membrane potential; Fura-2-FF for mitochondrial [$Ca^{2+}$] and TMRE for ${\Psi}_m$ or carboxy-SNARF-1 for pH were used. With this novel method, we found that the resting mitochondrial [$Ca^{2+}$] concentration was $1.03{\mu}M$. This $1{\mu}M$ cytosolic $Ca^{2+}$ could theoretically increase to more than 100 mM in mitochondria. However, the mitochondrial [$Ca^{2+}$] increase was limited to ${\sim}30{\mu}M$ in the presence of $1{\mu}M$ cytosolic $Ca^{2+}$. Our method solved the problem of NADH signal contamination during the use of Fura-2 analogs, and therefore the method may be useful when NADH interference is expected.

• 대한기계학회논문집B
• /
• 제25권4호
• /
• pp.561-571
• /
• 2001

The standard uncertainty of flowrate measurement is obtained by combining that of independent variables. Gravimetric and volumetric method were applied to determine the flowrate and the standard uncertainties of flowrate measurement by both methods were evaluated in accordance with the procedure recommended by International Organization for Standardization. The combined standard uncertainties of determining the flowrate were estimated from the sensitivity coefficient and the standard uncertainty of independent variables. For practical application, the methods for evaluating and expressing uncertainty in flow measurement were discussed. It was found that the uncertainties of the weighing and time measurement in gravimetric method, the volume and time measurement in volumetric method have dominant influence on that of flowrate measurement. With the quantitative analysis of the sensitivity coefficient, the contribution of the each variable uncertainty to the combined standard uncertainty of flowrate measurement is shown clearly.

• 한국정밀공학회:학술대회논문집
• /
• 한국정밀공학회 2006년도 추계학술대회 논문집
• /
• pp.87-88
• /
• 2006

• Journal of the Korean Society for Industrial and Applied Mathematics
• /
• 제4권2호
• /
• pp.143-152
• /
• 2000

As muscular contraction is sustained, the Fourier spectrum of the myoelectric signal is shifted toward the lower frequency. This spectral density is associated with muscle fatigue. This paper describes a quantitative measurement method that performs the measurement of localized muscle fatigue by tracking changes of median frequency based on stationary wavelet transform. Applying to the human masseter muscle, the proposed method offers the much information for muscle fatigue, comparing with the conventional FFT-based method for muscle fatigue measurement.

• 한국콘텐츠학회논문지
• /
• 제16권8호
• /
• pp.592-600
• /
• 2016

AAPM CT 성능 평가용 표준 팬텀을 이용한 특수의료장비 품질관리 검사 시, 평가자의 주관적인 평가로 인한 오류를 최소화 하고자 전산화된 평가 프로그램을 이용하여 유용성을 평가하고자 한다. 평가 팬텀으로 AAPM CT Performance Phantom을 사용하였고, 기본 촬영 조건은 품질관리검사와 동일하며, 평가프로그램으로 IMAGE J를 사용하였다. 정량적인 평가로 CT 감약계수와 노이즈측정, 균일도측정, 슬라이스 두께 측정, 대조도 분해능 측정, 공간 분해능 측정의 팬텀 영상을 평가프로그램을 이용하여 영상처리를 한 후 자동추출 된 결과로 평가 하였으며, CT 감약계수, 노이즈, 균일도 측정은 영상처리를 한 영상의 표준편차가 작아 더 균일하다고 평가하였고, 슬라이스 두께 측정은 팬텀영상의 측정값과의 비율 차로 인해 평가에 어려움이 있었다. 대조도 분해능은 원통형의 지름을 6회 측정하여 지름의 평균값과 표준편차를 구해 원의 형태를 평가하였으며, 공간 분해능은 합격기준을 포함하는 원의 그룹을 자동 추출한 결과 원의 개수를 모두 추출한 결과로 나타났다. 정성적인 평가로 원본영상과 영상 처리한 영상을 육안적으로 비교 평가 하였는데 영상처리 된 영상이 우수한 결과를 나타내었다. 위의 결과 등을 바탕으로 평가자의 주관적인 판단의 오류를 최소화하기 위해서는 정량적인 평가와 정성적인 평가가 함께 이루어져야 하고 전산화된 평가프로그램을 활용한다면 보다 더 효율적인 평가가 이루어 질 것이라고 사료된다.

• 대한기계학회논문집A
• /
• 제26권2호
• /
• pp.217-224
• /
• 2002

It is very important to measure and visualize the changes in the physical properties of fluid flow because this is the foundation of measurement techniques used in aerodynamics, heat transfer, plasma diagnostics, and stress analysis of transparent models. The optical methods are advantageous over probe-based techniques in the optical methods are of high speed, non-contact and are capable of providing full-field results with high spatial resolution. Therefore we propose the electronic speckle pattern interferometry(ESPI) that gives us a solution to overcome those limitations. In this paper the experimental results show qualitative and quantitative visualization of changes in the physical properties of the candle and alcohol lamp with 3D plotting. And we obtained the refractive index, mass density and temperature distribution of fluids. The results clearly show the process of flow phenomena and give the feasibility of quantitative interpretation of gasdynamics.

• Clinical and Experimental Pediatrics
• /
• 제48권5호
• /
• pp.461-468
• /
• 2005

The major function of immune system is to protect infections. The immune systems are composed of innate and adaptive immunity. In adaptive immunity, the cellular and humoral components interact each other. Neonates and infants are infected frequently, because immune systems are naive and easy to expose to infectious agents. The complete history and physical examination is essential to evaluate the child with recurrent infections. The environmental risk factors of recurrent infections are day care center, cigarette smoke, and air pollution. The underlying diseases such as immunodeficiency, autoimmune diseases, allergy, and disorders of anatomy or physiology increase the susceptibility to infections. In immunodeficiency, infections are characterized by severe, chronic, recurrent, and unusual microbial agents infection. The defects of antibody production are susceptible to sinopulmonary bacterial infections. T cells defects are vulerable to numerous organisms such as virus, fungi, bacteria and etc. The screening tests for immune functions are the quantitative and qualitative measurements of each immune components. A complete blood count with white blood cell, differential, and platelet provide quantitative informations of immune components. Total complement and immunoglobulin levels represent the humoral component. Antibody levels of previously injected vaccines also provide informations of the antigen specific antibody immune responses. T cell and subsets count is quantitative measurement of cell mediated immunity. Delayed hypersensitivity skin test is a crude measurement of T cell function. The long term outcome of children with recurrent infections is completely dependent on the underlying diseases, the initial time of diagnosis and therapy, continued management, and genetic counscelling.