• 제목/요약/키워드: quantitative evaluation models

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유전자수준에서 돌연변이 유발기전을 밝히는 Transgenic Mutagenesis Assay (Transgenic Mutagenesis Assay to Elucidaate the Mechanism of Mutation at Gene Level)

  • 류재천;윤지윤;조경혜;장일무
    • 한국환경성돌연변이발암원학회지
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    • 제18권1호
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    • pp.15-21
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    • 1998
  • Transgenic animal and cell line models which are recently developed and used in toxicology fields combined with molecular biological technique, are powerful tools to study the mechanism of mutation in vivo and in vitro, respectively. Transgenic models, which have exogenous DNA incorporated into their genome, carry recoverable shuttle vector containing reporter genes to assess endogenous effects or alteration in specific genes related to disease processes. The lac I and lac Z gnee most widely used as a mutational target in transgenic systems. The assay is performed by treatment with putative mutagenic agents, isolation of genomic DNA from cells or tissues, exposure the isolated DNA to in vitro packaging extract, plating and sequencing. The results from these processes provide not only mutant frequency as quantitative evaluation but also mutational spectrum as qualitative evaluation of various agents. Therefore we introduce and review the principle, detailed procedure and application of transgenic mutagenesis assay system in toxicology fields especially in mutagenesis and carcinogenesis.

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Data-Driven Approaches for Evaluating Countries in the International Construction Market

  • Lee, Kang-Wook;Han, Seung H.
    • 국제학술발표논문집
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    • The 6th International Conference on Construction Engineering and Project Management
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    • pp.496-500
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    • 2015
  • International construction projects are inherently more risky than domestic projects with multi-dimensional uncertainties that require complementary risk management at both the country and project levels. However, despite a growing need for systematic country evaluations, most studies have focused on project-level decisions and lack country-based approaches for firms in the construction industry. Accordingly, this study suggests data-driven approaches for evaluating countries using two quantitative models. The first is a two-stage country segmentation model that not only screens negative countries based on country attractiveness (macro-segmentation) but also identifies promising countries based on the level of past project performance in a given country (micro-segmentation). The second is a multi-criteria country segmentation model that combines a firm's business objective with the country evaluation process based on Kraljic's matrix and fuzzy preference relations (FPR). These models utilize not only secondary data from internationally reputable institutions but also performance data on Korean firms from 1990 to 2014 to evaluate 29 countries. The proposed approaches enable firms to enhance their decision-making capacity for evaluating and selecting countries at the early stage of corporate strategy development.

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프롬프트 엔지니어링(Prompt Engineering)을 활용한 '진료수행시험 연습용 챗봇(CPX Practicing Chatbot)' 시범 개발 (Pilot Development of a 'Clinical Performance Examination (CPX) Practicing Chatbot' Utilizing Prompt Engineering)

  • 김준동;이혜윤;김지환;김창업
    • 대한한의학회지
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    • 제45권1호
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    • pp.203-214
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    • 2024
  • Objectives: In the context of competency-based education emphasized in Korean Medicine, this study aimed to develop a pilot version of a CPX (Clinical Performance Examination) Practicing Chatbot utilizing large language models with prompt engineering. Methods: A standardized patient scenario was acquired from the National Institute of Korean Medicine and transformed into text format. Prompt engineering was then conducted using role prompting and few-shot prompting techniques. The GPT-4 API was employed, and a web application was created using the gradio package. An internal evaluation criterion was established for the quantitative assessment of the chatbot's performance. Results: The chatbot was implemented and evaluated based on the internal evaluation criterion. It demonstrated relatively high correctness and compliance. However, there is a need for improvement in confidentiality and naturalness. Conclusions: This study successfully piloted the CPX Practicing Chatbot, revealing the potential for developing educational models using AI technology in the field of Korean Medicine. Additionally, it identified limitations and provided insights for future developmental directions.

사이버 교수-학습과정에서 상호작용성 평가방법에 관한 탐색적 연구 (A Study on Quantitative Models for Evaluating Interactivity in Cyber Learning)

  • 김미량;장정무;한광현
    • 컴퓨터교육학회논문지
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    • 제7권1호
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    • pp.79-88
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    • 2004
  • 사이버 교수-학습환경이 활성화되면서 그 교육 과정의 핵심 요소로 상호작용의 중요성이 강조되고 있다. 그럼에도 사이버 학습에서의 상호작용성의 중요성을 강조한 연구는 쉽게 찾아볼 수 있으나 상호작용성의 특성상, 그 과정 자체를 확인하고 평가하는 방법에 대해서는 별다른 진전이 없었고 또 이를 계량적으로 평가하는데 어려움이 있었다. 이에, 본 연구는 이러한 추상적인 상호작용의 과정을 평가하고자 사이버 체제의 교수-학습과정에서 나타나는 상호작용 과정을 확인할 수 있는 정량적 데이터를 수집하였다. 이 데이터를 기초로 DEA기법과 가중치 적용기법의 두 가지 방법을 이용하여 상호작용서의 수준을 계량적으로 평가해 보았다. 이 두 가지 정량적 평가모형을 월별로 적용한 결과간의 상관계수와 서열상관계수를 살펴본 결과, 이 두 모형의 결과에는 큰 차이가 없음을 확인 할 수 있었다. 추상적인 상호작용의 과정을 정량적 접근을 통해 평가해 봄으로써 학습과정에서 발생하는 상호작용성의 정도를 검증할 수 있는 방법론을 제안하였다.

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선박 종류에 따른 내항성능 평가에 관한 연구 (A Study on the Evaluation of Seakeeping Performance with Ship Types)

  • 김순갑;박문수;공길영
    • 한국항해학회지
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    • 제18권2호
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    • pp.19-40
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    • 1994
  • Several factors can be chosen for evaluating seakeeping performance, such as deck wetness, propeller racing, slamming, rolling, vertical acceleration and vertical bending moment, in consi-deration of the safety of human being, cargo and ship. In fact, there are few developments for an evalua-tion method of seakeepting performance correponding with each ship's characteristics. The purpose of this paper is to develop an quantitative evaluation method of seakeeping performance according to ship types. The scope and the method of this study are as follow. (1) Obtain each response amplitude of ship's motion in waves by Ordinary Strip Method and apply it to short-crested, irregular wave for random process of the factors on seakeeping performance. (2) Define the evaluation index, the dangerousness, the maximum dangerousness and the evaluation diagram. (3) Figure out the different characteristics according to ship types by computer simulation of evaluating seakeeping performance. (4) Adopt vertical acceleration and one of rolling or lateral acceleration as the factors on seakeeping performance by clarifying the correlation of stochastic process. This study developed an evaluation method coincident with each ship's characteristics, and suggested a device for application to actual ship. This method might be useful in developing the practical system of seakeeping performance in accordance with ship types. The ship models for computer simulation are 175m container ship types, 93m tranning ship HANARA as passenger ship type, 259m bulk-carrier type and 164m pure car-carrier type.

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자동차 인간공학 개발 동향과 향후 과제 (Current Trends and Future Issues of Automotive Ergonomics)

  • 장치환;임성현
    • 대한인간공학회지
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    • 제29권1호
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    • pp.1-5
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    • 2010
  • The purpose of the paper is to review current trends and future issues of automotive ergonomics. The current trends include 1) universal design considering for regional differences, elderly drivers, female drivers, 2) quantification of driver's discomfort 3) trade-off between design trends and comfort, 4) digital ergonomic evaluation with digital human models 5) optimization of driver's interface. The future issues of automotive ergonomics cover 1) intelligent driver assistance system 2) Fun-to-drive and 3) differentiation from other vehicles based on ergonomics.

OpenCASCADE를 이용한 CAD 모델의 오류 진단 시스템의 개발 (Development of a Diagnosis System far CAD Model Errors using OpenCASCADE)

  • 양정삼;한순홍;최영;박상호
    • 한국자동차공학회논문집
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    • 제10권3호
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    • pp.151-158
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    • 2002
  • Automotive engineers involved in a new car project use various CAD systems that are chosen based on work requirements. For example, engineers in Hyundai Motors are using Pro/Designer and Alias fur the style design, but they use CATIA to design parts and assemblies, ANSYS for FEM analysis, and Pro/Engineer to design engines. Because they use different CAD systems, they have difficulties in collaborative design. Data, which contains errors, is transferred between CAD systems. It is difficult to find out such errors in a large CAD model. An evaluation method for CAD models has been developed in this study. This diagnosis tool analyses a STEP or an IGES file generated from a CAD system, and produces a quantitative error report. The tool has been tested with actual data sets. This paper proposes an algorithm that produces mathematical error values of entities of IGES models that have geometrical data, and entities of STEP models that have topological data, and inspects every part off model. To develop this system, we have used the OpenCASCADE kernel, which is an open source kernel developed by Matra Datavision of France.

都市林의 屋外레크레이션 機能과 價値의 計量的 評價에 關한 硏究 -都市林의 利用滿足度를 中心으로- (A Study on Quantitative Evaluation of Outdoor Recreation Functions and Values on Urban Forest)

  • 박찬용
    • 한국조경학회지
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    • 제18권3호통권39호
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    • pp.143-154
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    • 1990
  • This study aims at identifying factors and variables which have significant effects on users satisfaction with recreational activities and facilities in Apsan city natural park and therby establishing indicies of planning and / or development of urban forest. To test the causal models of this research, The data were gathered by self-administered questionnaires from 1,147 households in Taegu city which were selected by the multi-stage probabiling sampling method. The analysis of the data primarily consist of two phases : The first analysis dealt with exploratory factor analysis which identified major factors involved in satisfaction with recreational activities and facilities in Apasn city natural park and the second analysis tested the fit of causal models of this research to the data using LISREL methodology. The factor analysis identified that three significant factors are involved in satisfaction with recreational activities and five significant factors are inherent in satisfaction with recreational facilities. The second phase analysis tested the fit of the causal models for satisfaction with recreational activities and facilities to the data and identified statistically significant causal linkage among overall satisfaction with the park, other indogenous factors and exogenous variables. These significant relationships represent important factors and variables that should be considered in planning and/of development of the city natural park. On the basis of there significant causal relationships implications for planning and/or development of the city natural park were suggested.

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Evaluation and Comparison of the Solubility Models for Solute in Monosolvents

  • Min-jie Zhi;Wan-feng Chen;Yang-bo Xi
    • Korean Chemical Engineering Research
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    • 제62권1호
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    • pp.53-69
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    • 2024
  • The solubility of Cloxacillin sodium in ethanol, 1-propanol, isopropanol, and acetone solutions was measured at different temperatures. The melting property was also tested by using a differential scanning calorimeter (DSC). Then, the solubility data were fitted using Apelblat equation and λh equation, respectively. The Wilson model and NRTL model were not utilized to correlate the test data, since Cloxacillin sodium will decompose directly after melting. For comparison purposes, the four empirical models, i.e., Apelblat equation, λh equation, Wilson model and NRTL Model, were evaluated by using 1155 solubility curves of 103 solutes tested under different monosolvents and temperatures. The comparison results indicate that the Apelblat equation is superior to the others. Furthermore, a new method (named the calculation method) for determining the Apelblat equation using only three data points was proposed to solve the problem that there may not be enough solute in the determination of solubility. The log-logistic distribution function was used to further capture the trend of the correlation and to make better quantitative comparison between predicted data and the experimental ones for the Apelblat equation determined by different methods (fitting method or calculation method). It is found that the proposed calculation method not only greatly reduces the number of test data points, but also has satisfactory prediction accuracy.

Formalizing the Design, Evaluation, and Analysis of Quality of Protection in Wireless Networks

  • Lim, Sun-Hee;Yun, Seung-Hwan;Lim, Jong-In;Yi, Ok-Yeon
    • Journal of Communications and Networks
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    • 제11권6호
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    • pp.634-644
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    • 2009
  • A diversity of wireless networks, with rapidly evolving wireless technology, are currently in service. Due to their innate physical layer vulnerability, wireless networks require enhanced security components. WLAN, WiBro, and UMTS have defined proper security components that meet standard security requirements. Extensive research has been conducted to enhance the security of individual wireless platforms, and we now have meaningful results at hand. However, with the advent of ubiquitous service, new horizontal platform service models with vertical crosslayer security are expected to be proposed. Research on synchronized security service and interoperability in a heterogeneous environment must be conducted. In heterogeneous environments, to design the balanced security components, quantitative evaluation model of security policy in wireless networks is required. To design appropriate evaluation method of security policies in heterogeneous wireless networks, we formalize the security properties in wireless networks. As the benefit of security protocols is indicated by the quality of protection (QoP), we improve the QoP model and evaluate hybrid security policy in heterogeneous wireless networks by applying to the QoP model. Deriving relative indicators from the positive impact of security points, and using these indicators to quantify a total reward function, this paper will help to assure the appropriate benchmark for combined security components in wireless networks.