• 기본간호학회지
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• 제26권2호
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• pp.75-85
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• 2019

Purpose: The purpose of this study was to examine effects of music intervention on environmental stress and sleep quality in liver transplant patients who are receiving care in one-person isolation rooms of an ICU. Methods: The study was a quasi-experimental design pre-and-post nonequivalent control group. Participants were 37 patients (18 in the experimental group and 19 in the control group) who, after receiving liver transplant, were hospitalized in one-person isolation rooms of the ICU. The study covered patients admitted between August 2016 and December 2017. Earplugs and sleep shades were provided as ordinary care to both experimental and control groups, and music intervention was provided to the experimental group three times a day for 30 minutes each from the first day of hospitalization. Results: The first hypothesis, "The experimental group who received music intervention will experience a lower environmental stress level than the control group" was supported (Z=-3.212, p<.001). The second hypothesis, "The experimental group who received music intervention will experience a higher sleep quality than the control group" was also supported (t=3.715, p=.001). Conclusion: Findings show that music intervention is an effective nursing intervention to reduce environmental stress and improve sleep quality in liver transplant patients in the ICU.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제16권4호
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• pp.207-218
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• 2013

Long term outcomes after liver transplantation are major determinants of quality of life and of the value of this heroic treatment. As short term outcomes are excellent, our community is turning to take a harder look at long term outcomes. The purpose of this paper is to review these outcomes, and highlight proposed treatments, as well as pressing topics needing to be studied. A systemic review of the English literature was carried in PubMed, covering all papers addressing long term outcomes in pediatric liver transplant from 2000-2013. Late outcomes after pediatric liver transplant affect the liver graft in the form of chronic liver dysfunction. The causes include rejection particularly humoral rejection, but also de novo autoimmune hepatitis, and recurrent disease. The metabolic syndrome is a major factor in long term cardiovascular complication risk. Secondary infections, kidney dysfunction and malignancy remain a reality of those patients. There is growing evidence of late cognitive and executive function delays affecting daily life productivity as well as likely adherence. Finally, despite a good health status, quality of life measures are comparable to those of children with chronic diseases. Long term outcomes are the new frontier in pediatric liver transplantation. Much is needed to improve graft survival, but also to avoid systemic morbidities from long term immunosuppression. Quality of life is a new inclusive measure that will require interventions and innovative approaches respectful not only on the patients but also of their social circle.

• 생물환경조절학회지
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• 제23권2호
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• pp.139-143
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• 2014

본 연구는 폐쇄형 육묘 시스템에서의 파프리카 묘 생산에 적합한 재배 기간 및 암면 블록의 크기를 구명하기 위하여 수행되었다. 파프리카 종자를 세 가지 크기의 암면 블록($45{\times}40{\times}35$, $70{\times}70{\times}60$, $100{\times}100{\times}65mm$)에 파종하고 형광등을 인공 광원으로 이용하는 폐쇄형 육묘 시스템에서 23, 30, 37일간 재배하였다. 또한, 온실에서 $100{\times}100{\times}65mm$의 암면 블록을 이용하여 관행 재배한 파프리카 묘를 온실 처리구로 설정하였다. 육묘 일수와 관계없이 $70{\times}70{\times}60mm$의 암면 블록에서 육묘한 파프리카 묘의 지상부, 지하부 생육 및 R/S율이 가장 높았으며, 온실에서 관행 재배한 처리구보다 폐쇄형 육묘 시스템에서 재배한 파프리카 묘의 소질이 우수하였다. 폐쇄형 육묘 시스템과 온실에서 23, 30, 37일간 재배한 파프리카 묘를 암면 슬라브에 정식하고 초기 수량을 조사하였다. 파종후 125일의 파프리카 평균 과중은 암면 블록 크기와 육묘 일수의 영향을 거의 받지 않았으나, 단위 면적당 수량은 $70{\times}70{\times}60$와 $100{\times}100{\times}65mm$의 암면 블록을 이용하여 23일간 폐쇄형 육묘 시스템에서 재배한 처리구에서 가장 높았다. 따라서, 폐쇄형 육묘 시스템에서 파프리카 육묘시 관행 재배보다 작은 $70{\times}70{\times}60mm$의 암면 블록을 이용하고 육묘 일수를 23일로 단축하여도 우수한 품질의 파프리카 묘를 생산할 수 있음을 확인하였다.

• 임상간호연구
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• 제19권3호
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• pp.395-406
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• 2013

Purpose: This study was aimed to investigate the relationship between the level of stress and the quality of life among the adult recipients of living donor liver transplantation. Methods: Participants were 213 outpatients who received living donor liver transplantation at least 3 months prior to this study. Stress was measured using a modified version of the Kidney Transplant Recipient Stressor Scale (KTRSS), and the quality of life was measured using SF-36 version 2. Results: The mean of scaled stress level and quality of life of liver transplant recipients were $2.44{\pm}0.13$, $69.28{\pm}18.25$, respectively. There was an inverse correlation between those two parameters. Therefore lower stress could improve quality of life. Conclusion: For the liver transplantation recipients, improving the quality of life is to be the ultimate goal of health-related mediation. Liver transplantation recipients would need to cultivate self-care ability to manage stress, and improving their quality of life.

• Journal of Korean Biological Nursing Science
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• 제18권1호
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• pp.17-26
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• 2016

Purpose: Adherence to immunosuppressants is the key to prevent organ rejection in organ transplant recipients. The purpose of this study was to investigate current interventions to improve adherence to immunosuppressants in liver transplant recipients. Methods: A systemic literature search was done using PubMed, Embase, Cochrane Library, CINAHL and four Korean databases to identify experimental studies reported in English or Korean up to and including 2015. We identified eight intervention studies on the adherence to immunosuppressants in liver transplant recipients independently reviewed by two reviewers. The quality and risk of bias of the selected studies were assessed. Results: Education, conversion of regimen, and text messaging were identified as intervention techniques to improve adherence. We found positive results in three out of four studies implementing educational strategies, but the results were not sufficient to draw a definite conclusion. Conversion from a twice-daily tacrolimus-based regimen to a once-daily tacrolimus extended-release formula was used in three adult-only studies and its effectiveness was confirmed. One study showed that improved adherence and outcomes were effected by using text messaging with pediatric patients. Conclusion: Future research is needed to facilitate interventions to improve adherence to immunosuppressants in various ages of patients including pediatric/adolescent liver transplant recipients.

• Journal of Plant Biotechnology
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• 제3권2호
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• pp.59-66
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• 2001

Photoautotrophic micropropagation systems do not include sugar in the culture media. This characteristic provides advantages to scale up the micropropagation systems comparing photomixotrophic micropropagation systems. A closed, large-scale photoautotrophic micro-propagation for transplant production system has been developed at Chiba University, Japan. New concepts and technologies were adapted to produce high quality transplants at minimum usage of resources, and as scheduled. Newly developed software for production management was used to enhance the efficiency of the transplant production system. Currently, virus-free transplants of sweetpotato (Ipomoea batatas (L.) Lam.) are vegetatively propagated and produced under sterilized conditions in this system. This system can also be used for production of transplants of any other species including horticultural and woody plants with a minimum of modification.

• Journal of Gastric Cancer
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• 제18권4호
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• pp.379-391
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• 2018

Purpose: Gastric cancer (GC) patients with peritoneal metastasis (PM) have poor prognosis. Pressurized intraperitoneal aerosol chemotherapy (PIPAC) in combination with systemic chemotherapy is a novel treatment option for patients in stage IV of the disease. Materials and Methods: Between November 2015 and June 2018, prospective data collection was performed in 24 patients with GC and PM (median age, 57; range, 44-75 years). These patients underwent 46 PIPAC procedures with a median number of 2 interventions per patient (range, 1-6). A laparoscopic access was used and a combined therapy of cisplatin and doxorubicin aerosol was administered. Results: The median peritoneal carcinomatosis index before the 1st PIPAC was 14 (range, 2-36), and the median ascites volume in patients before the 1st PIPAC was 100 mL (range, 0-6 mL, 300 mL). Eleven patients, who received 2 or more PIPAC procedures, had decreased and stable volumes of ascites, while only 3 patients displayed increasing volume of ascites. The median overall survival was 121 days (range, 66-625 days) after the 1st PIPAC procedure, while 8 patients who received more than 3 PIPAC procedures had a median survival of 450 days (range, 206-481 days) (P=0.0376). Conclusions: Our data show that PIPAC is safe and well tolerated, and that the production of ascites can be controlled by PIPAC in GC patients. Patients, who received 2 or more PIPAC procedures, reported a stable overall quality of life. Further studies are required to document the significance of PIPAC as a palliative multimodal therapy.

• 생물환경조절학회지
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• 제11권1호
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• pp.40-44
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• 2002

플러그묘를 대량으로 생산할 수 있는 폐쇄형 묘생산 시스템을 개발하고자 본 연구가 수행되었다 또한 묘소질이 우수한 청장계 오이 플러그묘를 생산하는 데 필요한 적정 광환경 조건을 확립하고자 오이묘의 생장에 미치는 4수준의 광주기(18/6 h, 12/12 h, 9/15 h, 6/18h)와 4수준의 광합성유효광량자속(200, 300, 400, 500$\mu$mo1. m$^{-2}$ .s$^{-1}$)의 영향을 구명하였다. 인공광하에서 오이 플러그묘의 생장에 미치는 광주기의 영향은 광합성유효광량자속에 비해서 더 크게 나타났다. 폐쇄형 묘생산 시스템에서 생산된 오이묘의 줄기 직경, 지상부와 지하부 건물중, 엽수, 엽폭, 엽장 및 엽록소함량은 대조구에 비해서 유의성이 높게 나타났다. 한편 배축은 대조구에 비해서 유의성이 인정될 만큼 짧게 나타났다. 6/18h의 광주기와 200$\mu$mol. m$^{-2}$ .s$^{-1}$의 광합성유효광량자속에서 생산된 오이묘의 생장 특성은 자연광하에서 육묘된 경우와 유사하게 나타났다. 단일 식물인 오이의 특성을 고려할 때 상기 결과는 짧은 명기와 낮은 광량에서 묘소질이 균일한 청장계 오이 플러그묘의 생산이 가능함을 의미하는 것이다. 인공광하에서 식물묘를 생산할 경우 소비전력의 60~70%가 조명기구에 소요됨을 고려할 때 이러한 결과는 인공광형 묘생산 시스템을 이용한 오이 플러그묘의 생산에서 소비전력의 절감 방안에 해당하는 것이다.

• 한국농업기계학회:학술대회논문집
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• 한국농업기계학회 2000년도 THE THIRD INTERNATIONAL CONFERENCE ON AGRICULTURAL MACHINERY ENGINEERING. V.III
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• pp.764-769
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• 2000

A new transplant production system that produces high quality plug seedlings of specific crop has been studied. It is a plant factory designed to produce massive amount of virus free seedlings. The design concept for building this plant factory is to realize maximum energy efficiency and minimum initial investment and running cost. The basic production strategy is the sitespecific management. In this case, the management of the growth of individual plantlet is considered. This requires highly automated and information intensive production system in a closed aseptic environment the sterilized specific crops. One of the key components of this sophisticated system is the irrigation system. The conditions that this irrigation system has to satisfy are: 1. to perform the site specific crop management in irrigation and 2. to meet the no waste standard. The objective of this study is to develop an irrigation scheduling that can implement the no waste standard.

• 대한간호학회지
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• 제28권3호
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• pp.760-772
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• 1998

The purpose of this study was to explore the concept of quality of life for bone marrow transplant (BMT) survivors and to gain understanding of nursing interventions that may improve QOL in this population. The data was gathered from 32 BMT survivors using seven open-ended questions. The items were based on previous research of Ferrell et al., (1992). Content analysis was performed on written responses to seven questions regarding BMT and QOL. The results were as follows : 1. The meaning of QOL for BMT survivors were "being healt", "being able to take a role", "having relationships", "self-accomplishment", "peace of mind", "spiritual well-being", "economic stability" and "being alive". 2. The impact of BMT on physical well-being were "skin impairment", "digestive problems", "infections ", "fatigue/weakness", "arthralgia", "eye dryness". "weight gain", "amenorrhea" and "hand tremor". 3. The impact of BMT on psychological well-being were "fear of recurrence", "sence of peace" and "hope". 4. The impact of BMT on socioeconomic status were "financial burden", "limitation of social activities" and "sence of withdrawal". 5. The impact of BMT on spiritual well-being were "dependency on Supreme Being", "spiritual arousal " and "spiritual maturity". The findings of the study will be useful in constructing a instrument to measure QOL in BMT and in understanding the conceptual basis of QOL for the BMT population.ency on Supreme Being", "spiritual arousal " and "spiritual maturity". The findings of the study will be useful in constructing a instrument to measure QOL in BMT and in understanding the conceptual basis of QOL for the BMT population.L for the BMT population.