• 한국진공학회:학술대회논문집
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• 한국진공학회 1997년도 제13회 학술발표회 논문개요집
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• pp.123-123
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• 1997

• 한국진공학회:학술대회논문집
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• 한국진공학회 2008년도 제34회 동계학술대회 초록집
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• pp.365-365
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• 2008

• 천문학회지
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• 제12권1호
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• pp.7-9
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• 1979

The rate of gravitational quadrupole radiation is derived in the formalism of source theory. It is also shown that gravitational superradiance is theoretically possible.

• 한국광학회:학술대회논문집
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• 한국광학회 2001년도 하계학술발표회
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• pp.94-95
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• 2001

• 한국세라믹학회:학술대회논문집
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• 한국세라믹학회 2002년도 추계총회 및 연구발표회 초록집
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• pp.131.2-131
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• 2002

• 한국자기학회:학술대회 개요집
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• 한국자기학회 2005년도 동계학술연구발표회 및 2차 아시안포럼
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• pp.38-39
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• 2005

• 한국자기공명학회:학술대회논문집
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• 한국자기공명학회 2002년도 제20회 학술발표회
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• pp.16-16
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• 2002

• Mass Spectrometry Letters
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• 제7권3호
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• pp.69-73
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• 2016

High-resolution quadrupole-Orbitrap mass spectrometry (HRMS), with high-resolution (> 10,000 at full-width at half-maximum) and accurate mass (< 5 ppm deviation) capabilities, plays an important role in the structural elucidation of drug metabolites in the pharmaceutical industry. ML106, a derivative of imidazobenzimidazole, decreased melanin content and tyrosinase activity in a dose-dependent manner. Here, we investigated the phase 1 metabolic pathway of ML106 using HRMS in human liver microsomes (HLMs) and recombinant cDNA-expressed cytochrome P450 (CYP). After the incubation of ML106 with pooled HLMs and recombinant cDNA-expressed CYP in the presence of NADPH, five phase 1 metabolites, including three mono-hydroxylated metabolites (M1-3) and two di-hydroxylated metabolites (M4 and M5), were investigated. The metabolite structures were postulated by the elucidation of protonated mass spectra using HRMS. The CYP isoforms related to the hydroxylation of ML106 were studied after incubation with recombinant cDNA-expressed CYP. Here, we identified the phase 1 metabolic pathway of ML106 induced by CYP in HLMs.

• 한국음향학회:학술대회논문집
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• 한국음향학회 2002년도 하계학술발표대회 논문집 제21권 1호
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• pp.469-474
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• 2002

In recent years, modularization of engine parts has increased the application of plastic products in air intake systems. Plastic intake manifolds provide many advantages including reduced weight, contracted cost, and lower intake air temperatures. These manifolds, however, have some weakness when compared with customary aluminium intake manifolds, in that they have low sound transmission loss because of their lower material density. This low transmission loss of plastic intake manifolds causes several problems related to flow noise, especially when the throttle is opened quickly. The physical processes, responsible for this flow noise, include turbulent fluid motion and relative motion of the throttle to the airflow. The former is generated by high-speed airflow in the splits between the throttle valve and the inner-surface of the throttle body and surge-tank, which can be categorized into the quadrupole source. The latter induces the unsteady force on the flow, which can be classified into the dipole source. In this paper, the mechanism of noise generation from the turbulence is only investigated as a preliminary study. Stochastic noise source synthesis method is adopted for the analysis of turbulence-induced, i.e. quadrupole noise by throttle at quick opening state. The method consists of three procedures. The first step corresponds to the preliminary time-averaged Navier-Stokes computation with a $k-\varepsilon$ turbulence model providing mean flow field characteristics. The second step is the synthesis of time-dependent turbulent velocity field associated with quadrupole noise sources. The final step is devoted to the determination of acoustic source terms associated with turbulent velocity. For the first step, we used market available analysis tools such as STAR-CD, the trade names of fluid analysis tools available on the market. The steady state flows at three open angle of throttle valve, i.e. 20, 35 and 60 degree, are numerically analyzed. Then, time-dependent turbulent velocity fields are produced by using the stochastic model and the flow analysis results. Using this turbulent velocity field, the turbulence-originated noise sources, i.e. the self-noise and shear-noise sources are synthesized. Based on these numerical results, it is found that the origin of the turbulent flow and noise might be attributed to the process of formulation and the interaction of two vortex lines formed in the downstream of the throttle valve. These vortex lines are produced by the non-uniform splits between the throttle valve and inner cylinder surface. Based on the analysis, we present the low-noise design of the inner geometry of throttle body.

• 한국산학기술학회논문지
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• 제19권11호
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• pp.1-7
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• 2018

마이크로칼럼에서는 전자빔을 스캔하기 위해 초소형화된 정전디플렉터를 사용하는 경우가 많다. 주로 두 개의 8중극 디플렉터(double octupole deflector)를 사용하는 경우가 많은데, 이는 스캔 영역을 넓게 하면서도 전자빔이 대물렌즈를 통과할 때에 광축 근처에 위치하도록 함으로써 수차를 작게 유지할 수 있는 장점이 있기 때문이다. 마이크로칼럼은 최종적으로는 멀티 칼럼 형태로 사용하여 전자빔 장비의 throughput을 높이고자 하는 목적으로 연구가 되고 있는데, 칼럼의 수가 많아지게 되면 각 부품에 연결되는 배선의 수도 함께 증가하게 된다. 이에 따라 정전렌즈, 디플렉터 등의 마이크로칼럼 부품 배선을 진공 챔버 밖에 있는 제어장비와 연결하는 과정에서 실질적인 문제에 봉착하게 된다. 이러한 문제를 완화하기 위하여 렌즈 수를 최소화할 수 있도록 대물렌즈를 제거한 마이크로칼럼 구조를 선택하여, 변형된 4중극 및 8중극 디플렉터의 동작을 전산모사 방법으로 연구하였다. 기본적으로 MEMS 공정을 적용하기 용이한 실리콘 디플렉터 구조에서 각 전극의 크기를 동일하게 하지 않고, 서로 다른 크기의 전극을 교대로 배치하도록 디자인하였다. 8중극과 4중극 디플렉터 각각에서 디플렉터 전압을 인가하는 구동전극의 크기에 변화를 주었을 때 스캔 영역과 디플렉터 중심점에서의 전기장의 변화를 조사하여 비교하였다. 스캔 영역은 디플렉터전압에 따라 선형적으로 비례하였다. 스캔영역과 중심점에서의 전기장 세기 모두 8중극 디플렉터에 비해 4중극 디플렉터에서 더 크게 나타났으며, 전극의 크기에 따라 약 1.3 ~ 2.0 배 큰 것으로 조사되었다.