• Title/Summary/Keyword: pulse 시간

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Application of a Single-pulsatile Extracorporeal Life Support System for Extracorporeal Membrane Oxygenation -An experimental study - (단일 박동형 생명구조장치의 인공폐 적용 -실험연구-)

  • Kim, Tae-Sik;Sun, Kyung;Lee, Kyu-Baek;Park, Sung-Young;Hwang, Jae-Joon;Son, Ho-Sung;Kim, Kwang-Taik;Kim. Hyoung-Mook
    • Journal of Chest Surgery
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    • v.37 no.3
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    • pp.201-209
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    • 2004
  • Extracorporeal life support (ECLS) system is a device for respiratory and/or heart failure treatment, and there have been many trials for development and clinical application in the world. Currently, a non-pulsatile blood pump is a standard for ECLS system. Although a pulsatile blood pump is advantageous in physiologic aspects, high pressure generated in the circuits and resultant blood cell trauma remain major concerns which make one reluctant to use a pulsatile blood pump in artificial lung circuits containing a membrane oxygenator. The study was designed to evaluate the hypothesis that placement of a pressure-relieving compliance chamber between a pulsatile pump and a membrane oxygenator might reduce the above mentioned side effects while providing physiologic pulsatile blood flow. The study was performed in a canine model of oleic acid induced acute lung injury (N=16). The animals were divided into three groups according to the type of pump used and the presence of the compliance chamber, In group 1, a non-pulsatile centrifugal pump was used as a control (n=6). In group 2 (n=4), a single-pulsatile pump was used. In group 3 (n=6), a single-pulsatile pump equipped with a compliance chamber was used. The experimental model was a partial bypass between the right atrium and the aorta at a pump flow of 1.8∼2 L/min for 2 hours. The observed parameters were focused on hemodynamic changes, intra-circuit pressure, laboratory studies for blood profile, and the effect on blood cell trauma. In hemodynamics, the pulsatile group II & III generated higher arterial pulse pressure (47$\pm$ 10 and 41 $\pm$ 9 mmHg) than the nonpulsatile group 1 (17 $\pm$ 7 mmHg, p<0.001). The intra-circuit pressure at membrane oxygenator were 222 $\pm$ 8 mmHg in group 1, 739 $\pm$ 35 mmHg in group 2, and 470 $\pm$ 17 mmHg in group 3 (p<0.001). At 2 hour bypass, arterial oxygen partial pressures were significantly higher in the pulsatile group 2 & 3 than in the non-pulsatile group 1 (77 $\pm$ 41 mmHg in group 1, 96 $\pm$ 48 mmHg in group 2, and 97 $\pm$ 25 mmHg in group 3: p<0.05). The levels of plasma free hemoglobin which was an indicator of blood cell trauma were lowest in group 1, highest in group 2, and significantly decreased in group 3 (55.7 $\pm$ 43.3, 162.8 $\pm$ 113.6, 82.5 $\pm$ 25.1 mg%, respectively; p<0.05). Other laboratory findings for blood profile were not different. The above results imply that the pulsatile blood pump is beneficial in oxygenation while deleterious in the aspects to high pressure generation in the circuits and blood cell trauma. However, when a pressure-relieving compliance chamber is applied between the pulsatile pump and a membrane oxygenator, it can significantly reduce the high circuit pressure and result in low blood cell trauma.

Variation of Vital Sign according to Time in Full Immersion of Hot and Cool Bath (온.냉욕 전신침수욕시 기간에 따른 vital sign의 변화)

  • Yi, Seung-Ju
    • Journal of Korean Physical Therapy Science
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    • v.3 no.3
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    • pp.35-49
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    • 1996
  • This study was conducted to see variation of vital sign of hot and cool bath according to time, a questionnair survey and measurement was carried out for 32 students(sophomore) of department of physical therapy Andong Junior College on the 27th of June, 1995. The result were as follows: The average systolic blood pressure(SBP) of stability for 32 college students who were measured was 105.3mmHg, the average diastolic blood pressure(DBP) was 67.3mmHg, the average pulse frequency(PF) was 70.7(frequency/min), the average respiratory frequency (RF) was 15.6 (frequency/min), and the body temperature(BT) was $36.6^{\circ}C$. As time went on, SBP for 32 students who were measured in hot bath according to stability, 3 min, 6 min, 9 min, and 12 min was decreased(105.15 mmHg, 104.69mmHg, 104.24 mmHg, 103.03 mmHg, and 96.69 mmHg)(P=0.3006). SBP was decreased in cool bath, too(105.15 mmHg, 103.33 mmHg, 103.33 mmHg, and 100.91 mmHg), but it at 12 min was a little higher(l03.09 mmHg)(P=0.7566). As time went on, DBP according to stability, 3 min, 6 min, 9 min, and 12 minutes was decreased in hot bath(66.82 mmHg, 65.45 mmHg, 64.54 mmHg, 63.03 mmHg, and 59.39 mmHg)(P=0.0906). It was similar in cool bath(66.82 mmHg, 67.87 mmHg, 68.48 mmHg, 67.87 mmHg, and 68.78)(P=0.9654). As time went on, PF was significantly increased in hot bath(70.42 times, 86.96 times, 93.57 times, 99.30 times, and 101.78 times)(P=0.0001). It was a little increased in cool bath, too (70.42 times, 70.85 times, 71.63 times, 71.06 times, and 71.45 times)(P=0.9803). As time went on, RF was significantly increased in hot bath(15.75 times, 19.09 times, 22.09 times, 24.94 times, and 26.48 times)(P=0.0001). I t in cool bath of stability, 3 min, and 6 min was a little increased(15.75 times, 19.30 times, 19.39 times), but it in 9 min(18.67 times), and 12 min(18.09 times) was a little decreased(P=0.0176). As time went on, BT was significantly increased in hot bath($36.63^{\circ}C,\;37.45^{\circ}C,\;37.81^{\circ}C,\;38.12^{\circ}C,\;38.33^{\circ}C$)(P=0.0001). It was a little increased in cool bath of stability and 3 min($36.63^{\circ}C,\;37.40^{\circ}C$), but others are similar($37.33^{\circ}C,\;37.37^{\circ}C$, and $37.36^{\circ}C$)(P=0.0001). It was revealed by this study, SBP and DBP according to time in hot and cool bath were decreased. PF, RF, and BT in hot bath were higher, RF and BT in cool bath were higher too. but PF was similar.

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Prevalence of Ruminal Lactic Acidosis and Clinical Assessments of Four Therapeutics in Goats of Bangladesh (방글라데시 염소에서 유산증의 분포 및 4가지 치료법의 임상적 적용)

  • Rahman, Md. Mahbubur;Islam, Mohammad Saiful;Adam, G.O.;Alam, Md. Rafiqul;You, Myung-Jo
    • Journal of Veterinary Clinics
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    • v.31 no.3
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    • pp.199-205
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    • 2014
  • Acidosis conditions either acute or chronic following ingestion of excessive amounts of readily fermented carbohydrate are great production problems for goat in Bangladesh. This study designed to investigate the prevalence of lactic acidosis and then response to different therapeutic agents. For this purpose, 1,128 goat were examined at outdoor District Veterinary Hospital, Faridpur, Bangladseh for treatment of which 40 goats were found positive for lactic acidosis showing 3.55% prevalence of disease. The highest occurrence found in female (4.64%) of over 3 years age (4.64%) in indigenous goat (2.7%). For therapeutic assessment the forty affected goats were divided into four groups A, B, C and D comprising of 10 animals each. Group A were given magnesium hydroxide 8% w/v at 1 g/kg body weight orally. In group B magnesium hydroxide 8% w/v at a dose as group A combination with 7.5% sodium bicarbonate at the rate of 0.9 ml/Kg body weight intravenously administered. Goat in group D were treated with mixture of ginger, nuxvomica, sodium carbonate, cobalt sulphate, dried ferrous sulphate and thiamin mononitrate at the rate of 1 g/kg body weight orally. Goat of group C treated with combination drugs of group A, B and D. The rectal temperature, pulse rate, respiration rate, was performed before and after treatment. It was found that the highest recovery in group C with an average period of $21{\pm}1.8$ hours. It was concluded that lactic acidosis is a common disease of goats and its severity can be effectively reduced by using combination drugs.

A Study on Improving Pitch Search for Vocoder (보코더에서 피치검색 성능개선에 관한 연구)

  • Baek, Geum-Ran;Bae, Myung-Jin
    • The Journal of the Acoustical Society of Korea
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    • v.31 no.7
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    • pp.419-426
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    • 2012
  • The pitch searching is a vital process in a vocoder. Generally, the method of pitch searching is employed after highlighting the periodicity, where a correlation is identified with the signal by changing the interval of two pulses. When the correlation value reaches the peak, the pitch can be found by the pulse interval because it is the repetition interval with most striking period. However if the identified period happens to be one of half period, double period or triple period, this cannot be considered as the pitch period. Many methods were suggested to solve this problem. An inaccurate pitch could be obtained as well, when there is an interval where signal amplitude is not constant but varies abruptly in the frame. To solve this matter, searching the pitch by dividing a frame into various subframes is adopted, but too much calculation has to be followed while it leads the correct value. This paper suggests an algorithm to resolve these two problems. First, to search the pitch after advance correction of the signal energy level with an estimated overall energy change ratio in the frame before pitch search to reduce half period, double period and triple period is suggested. Second, to vary the number of subframes by predicting the amplitude change rate in the frame by the energy ratio obtained by the above-mentioned method is advised. If these two methods are applied, the pitch searching time can be reduced and the general pitch searching performance can be improved without affecting the sound quality in the synthesized signal.

A Study on the Security of Infrastructure using fiber Optic Scattering Sensors (광섬유 산란형 센서를 이용한 사회기반시설물의 보안에 관한 연구)

  • Kwon, Il-Bum;Yoon, Dong-Jin;Lee, Seung-Seok
    • Journal of the Korean Society for Nondestructive Testing
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    • v.24 no.5
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    • pp.499-507
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    • 2004
  • We have studied tile detection techniques, which can determine the location and the weight of an intruder into infrastructure, by using fiber-optic ROTDR (Rayleigh optical time domain reflectometry) sensor and fiber-optic BOTDA (Brillouin Optical time domain analysis) sensor, which can use an optical fiber longer than that of ROTDR sensor Fiber-optic sensing plates of ROTDR sensor, which arc buried in sand, were prepared to respond the intruder effects. The signal of ROTDR was analyzed to confirm the detection performance. The constructed ROTDR could be used up to 10km at the pulse width of 30ns. The location error was less than 2 m and the weight could be detected as 4 grades, such as 20kgf, 40kgf, 60kgf and 80kgf. Also, fiber optic BOTDA sensor was developed to be able to detect intrusion effect through an optical fiber of tells of kilometers longer than ROTDR sensor. fiber-optic BOTDA sensor was constructed with 1 laser diode and 2 electro-optic modulators. The intrusion detection experiment was peformed by the strain inducing set-up installed on an optical table to simulate all intrusion effect. In the result of this experiment, the intrusion effort was well detected as the distance resolution of 3m through the fiber length of about 4.81km during 1.5 seconds.

Study of Catalytic Filter on the Removal of Dust and HVOC (촉매필터를 이용한 먼지 및 HVOC 제거 특성 연구)

  • Jeong, Soon Kwan;Park, Young Ok
    • Applied Chemistry for Engineering
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    • v.19 no.1
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    • pp.80-85
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    • 2008
  • Catalytic filter is capable of performing shallow bed dust filtration plus a catalytic reaction, promoted by a catalyst deposited in its inner structure. Such a feature may allow potential cost and space reduction in several environmental applications. Dust filtration and halogenated volatile organic compound (1,2-dichlorobenzene) destruction were carried out in a lab-scale reactor. $WO_3-V_2O_5/TiO_2$ supplied by MaGreen, which showed high catalytic acitivity at low temperature, was used as a catalyst. P-84 that can be operated under $250^{\circ}C$ was used as a felt. The catalytic activity and filtration efficiency of catalytic filters were investigated under the operating conditions, including temperature, face velocity, and dust concentration. The catalytic activity of catalytic filter increased with increasing temperature and the amount of catalyst loaded. The test results showed that the filtration efficiency was primarily affected by the face velocity. Pressure drop variations as a function of time were investigated for a variety of conditions. In case of virgin filter, a dramatic decrease in the pulse interval and a slightly increase in the base line pressure drop were observed. A relatively slow pressure drop build-up was recorded for the catalytic filter due to smooth and slippery surface characteristics of nanofiber. The catalytic filter indicated that high filtration efficiency over 99.98% and high catalytic activity over 90% at 1 m/min and $210^{\circ}C$.

Operatonal characteristics of the PLS linac vacuum system (PLS 선형가속기 진공계의 운전특성)

  • 김임경;박용정;김경렬;남궁원
    • Journal of the Korean Vacuum Society
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    • v.5 no.4
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    • pp.269-277
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    • 1996
  • The vacuum systems of PLS linac provides average pressure of $2.6\times 10^{-6}$Pa under high power microwave of 54 MW peak with 4.1 $\mu \textrm s$ pulse width and 10 Hz repetition rates. The base pressure of system is$2.4\times 10^{-6}$Pa with 45$^{\circ}C$ cooling water. The outgassing rate of the system is decreased from $3.0\times 10^{-11}Torr-l/sec-\textrm{cm}^2$ at the initial stage after installation to $1\times 10^{-12}Torr-l/sec-\textrm{cm}^2$ at present. Total accumulated microwave energy dose is about 140 GJ per module. All ion pumps are working under saturated regime and effective pumping speeds of 60 I/s, 230 I/s ion pumps are 45 I/s, 65 I/s, 140 I/s under the operating range. Main problems occurred in recent year are troubles of ion pump controller and vacuum gauge controller, vacuum leak of energy doubler window and electron gun ceramic, and water leak in the dummy load of acceleraing columns. Total of 41 troubles with 140. 8 hours down time give good system availability of 98%. Down time can be reduced by high power waveguide valves and water dummy loads under development, and then availability is expected to be increased up to 99.5%.

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Autonomic Nervous System response affected by 3D visual fatigue evoked during watching 3D TV (3D TV 시청으로 유발된 시각피로가 자율신경계 기능에 미치는 영향)

  • Park, Sang-In;Whang, Min-Cheol;Kim, Jong-Wha;Mun, Sung-Chul;Ahn, Sang-Min
    • Science of Emotion and Sensibility
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    • v.14 no.4
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    • pp.653-662
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    • 2011
  • As technology in 3D industry has rapidly advanced, a lot of studies primarily focusing on visual function and cognition have become vigorous. However, studies on effect of 3D visual fatigue on autonomic nervous system have not less been conducted. Thus, this study was to identify and determine the effect that might have a negative influence on sympathetic nervous system, parasympathetic nervous system, and cardiovascular system. Fifteen undergraduates (female: 9, mean age: $22.53{\pm}2.55$) participated and were sat on a comfortable chair, viewing a 3D content during about 1 hour. Cardiac responses like SDNN(standard deviation of RR intervals), RMS-SD(root mean squared successive difference), and HF/LF ratios extracted from the measured PPG(Photo-PlethysmoGram) before viewing 3D were compared to those after viewing 3D. The results showed that after subjects watched the 3D, responses in sympathetic nervous system and parasympathetic nervous system were activated and deactivated, respectively relative to those before watching the 3D. The results showed that HF/LF ratio, Ln(LF), and Ln(HF) after viewing 3D were significantly reduced relative to those before viewing 3D. No significant effects were observed in SDNN and RMS-SD. Results obtained in this study showed that visual fatigue induced by watching 3D adversely influenced autonomic nervous system, and thereby reduced heart rate variability causing sympathetic nervous acceleration.

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Determination of Estrone by Adsorptive Stripping Voltammetry (흡착 벗김 전압전류법에 의한 에스트론의 정량)

  • Hong, Taekee;Kyong, Jin Burm;Lee, Hyun Jung;Czae, Myung-Zoon
    • Analytical Science and Technology
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    • v.12 no.1
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    • pp.34-39
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    • 1999
  • Estrone such as estriol and estradiol can not be determined by votammetric methods, because these are electrochemically inactive in the potential windows for mercury drop electrode. Nitro-derivatives of estrone are electro active and nitration of estrone is accomplished by heating the solution involving estrone and sodium nitrite in a water-bath at $100^{\circ}C$ for 30 min. Such nitro-derivatives are determined directly by voltammetry. The electrochemical behavior for nitrated estrone was investigated by cyclic voltammetry. The trace estrone was determinated by differential pulse adsorptive cathodic stripping voltammetry. Nitrated estrone gives a well defined voltammetric wave at ca. - 0.61 V (vs. Ag/AgCl electrode). The electrochemical reaction was irreversible process in sodium borate buffer at pH 11 and nitrated estrone was strongly adsorbed on the surface of mercury electrode. The optimal experimental conditions for the determination of nitrated esterone were found to be 0.05 M sodium nitrate, 0.01 M sodium borate, pH 11.0, and an accumlation potential of 0.10 V (vs. Ag/AgCl). The detection limit was as low as $1{\times}10^{-9}M$ for estrone with 2 min accumulation time.

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Mobile phone payment system using a light signal (휴대폰의 광원을 이용한 디지털 카드 시스템)

  • Hu, Moon-Heang;Shin, Moon-Sun;Ryu, Kuen-Ho
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.10 no.6
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    • pp.1237-1244
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    • 2009
  • In this paper, we proposed a mobile phone payment system using light signal containing payment related information. The digicard system we proposed creates virtual mobile card such as credit numbers and the created information is loaded in mobile phone. The virtual card information should be changed to pulse signal by light signal devices of mobile phone and the specific digicard system reader is able to read light signal. In recent years, a mobile phone payment system has been developed in order to provide user's convenience. But the mobile phone payment system has problems such as the production costs and complex and large size. In order to solve the aforementioned problems, we proposed mobile phone payment system being implemented by updating software without additional hardware modules. Therefore it is possible to apply the proposed digicard system to all kinds of mobile phone. Also encryption module is implemented to solve the problem of the security and privacy. According to an aspect of the present invention, there is provided a mobile phone payment system using a light signal containing payment-related information, comprising: a mobile phone; a photo receiver: and a control server.