• Molecules and Cells
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• v.37 no.12
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• pp.873-880
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• 2014

In our previous study, miRNA-183, a miRNA in the miR-96-182-183 cluster, was significantly over-expressed in esophageal squamous cell carcinoma (ESCC). In the present study, we explored the oncogenic roles of miR-183 in ESCC by gain and loss of function analysis in an esophageal cancer cell line (EC9706). Genome-wide mRNA micro-array was applied to determine the genes that were regulated directly or indirectly by miR-183. 3'UTR luciferase reporter assay, RT-PCR, and Western blot were conducted to verify the target gene of miR-183. Cell culture results showed that miR-183 inhibited apoptosis (p < 0.05), enhanced cell proliferation (p < 0.05), and accelerated G1/S transition (p < 0.05). Moreover, the inhibitory effect of miR-183 on apoptosis was rescued when miR-183 was suppressed via miR-183 inhibitor (p < 0.05). Western blot analysis showed that the expression of programmed cell death 4 (PDCD4), which was predicted as the target gene of miR-183 by microarray profiling and bioinformatics predictions, decreased when miR-183 was over-expressed. The 3'UTR luciferase reporter assay confirmed that miR-183 directly regulated PDCD4 by binding to sequences in the 3'UTR of PDCD4. Pearson correlation analysis further confirmed the significant negative correlation between miR-183 and PDCD4 in both cell lines and in ESCC patients. Our data suggest that miR-183 might play an oncogenic role in ESCC by regulating PDCD4 expression.

• Journal of Korean Library and Information Science Society
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• v.52 no.2
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• pp.107-126
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• 2021

A status analysis and focus group interviews with librarians, school librarians and experts were conducted to find a new direction for revitalization of 19 public libraries affiliated to the Chungcheongnam-do Office of Education in the context of the advent of a new educational environment following the 4th industrial revolution. Through the research method, the knowledge experience edu library through the library community school was set as the vision of a public library belonging to the Chungnam Office of Education. The direction of public library service as an edu-library was divided into specialization as an educational library, life cycle customized service, knowledge experience-oriented service, and 4th industrial revolution intelligent information society service. Based on the traditional functions of the library, the space that the future public library should have was presented as an experiential learning space. In this study, a specialized direction for strengthening the educational function of libraries belonging to the Chungnam Office of Education was presented, which will contribute to finding ways to cooperate with schools and school libraries, and will provide a basis for preparing directions for libraries belonging to other regional offices of education.

• Safety and Health at Work
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• v.6 no.2
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• pp.104-113
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• 2015

Background: Given the long hours on the road involving multiple and interacting work stressors (i.e., delivery pressures, irregular shifts, ergonomic hazards), commercial drivers face a plethora of health and safety risks. Researchers goal was to determine whether and to what extent long-haul trucker work schedules influence sleep duration and quality. Methods: Survey and biometric data collected from male long-haul truck drivers at a major truckstop in central North Carolina over a six month period. Results: Daily hours worked (mean = 11 hours, 55 minutes) and frequency of working over government-mandated daily HOS regulations (23.8% "frequently or always") were statistically significant predictors of sleep duration. Miles driven per week (mean = 2,812.61), irregular daily hours worked (63.8%), and frequency of working over the daily hour limit (23.8% "frequently or always") were statistically significant predictors of sleep quality. Conclusion: Implications of findings suggest a comprehensive review of the regulations and operational conditions for commercial motor vehicle drivers be undertaken.

• Journal of Preventive Medicine and Public Health
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• v.39 no.1
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• pp.7-12
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• 2006

Throughout the century, based on the precedent set by Flexner in the United States, almost every subsequent report on the reform of medical education has pointed out the need for more prevention-oriented teaching in the curriculum. This has been particularly so in countries like Korea where the basic public health services have been so important for the improvement of health of the people. And, in fact, preventive medicine and public health have contributed a great deal to the prevention of communicable diseases and prolongation of life expectancy. Recently, however, along with the educational reform that emphasizing the interdisciplinary teaching, integration of basic science and clinical education, and centralization of responsibility for the medical education curriculum, concerns are being voiced by preventive medicine educators. These concerns are primarily centered around the fear that the implementation of interdisciplinary, centrally administered courses would result in a weakening of content and teaching expertise as well as a loss of departmental power and control. This paper foresees that preventive medicine and public health will be more important in Korea in the future and proposes that preventive medicine educators will have to step forward and turn the challenges of curricula restructuring into opportunities to expand the role of preventive medicine in the curricula of their institutions.

• The Journal of Korean Society for School & Community Health Education
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• v.20 no.1
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• pp.85-95
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• 2019

Objectives: This study is to examine the influences of three sub-factors of resilience on academic burn out among a group of university students, with low resilience, majored in public health. Methods: The survey was made during January 1 to 13, 2017 and after checking the resilience scores of 166 respondents and the questionnaires of 115 respondents, whose scores were less than 195, an average score of Korea, were selected and analyzed using AMOS. Results: The average resilience and academic burn-out scores were 173 and 2.96, respectively. The goodness-of-fit of proposed model showed RMSEA=0.068, GFI=0.916, NFI=0.901, IFI=0.963, CFI=0.962 so, final measurement model was selected. The analysis of the suggested model showed that among three sub-factors of resilience, only self-control ability had a negative(-) effect on academic burnout and two others were shown to have no effects. Conclusion: By researching and introducing a education method that could enhance self-control ability, it would effectively reduce academic burnout in university students with low resilience and majored in public health.

• Child Health Nursing Research
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• v.11 no.2
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• pp.221-228
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• 2005

Purpose: The purpose of this study was to determine the effect of an education program promoting safety knowledge and safety practice for mothers with infants. Method: This education was provided at two public health centers in Kyunggi Province. A non-equivalent control group pretest-post test design was used, and the participants were 95 mothers in the experimental group, and 44 mothers in the control group. Data were collected using a questionnaire, and were analyzed with the SPSS program. Results: After the group education sessions on safety management at the public health centers, the mean scores for knowledge and practice of safety in the experimental group were significantly higher than that of mothers in the control group mothers. Also, after the safety education, mothers in the experimental group perceived a higher priority in safety in child care than they had before the education program. Conclusion: The education for mothers with infants regarding the child safety was effective in promoting knowledge and practice of safety for infants.

• Hwankyungkyoyuk
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• v.20 no.1
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• pp.106-117
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• 2007

The purpose of this study was to evaluate the environmental education of public servants in National Institute of Environmental Human Resource Development(NIERD). Based on CIPP model, Evaluation areas and items were made. The data were collected through interviews, questionnaires and training and development team's internal information from November, 2005 to January, 2006. Based on the interviews and survey of 11 employee from training and development team, context factors, input factors, process factors, product factors were evaluated. The major findings of this study were as follows: First, the problem of the environmental education of environmental officials indicated lack of interest about education of Ministry of Environment, lack of education expense, lack of expertise of employee in training and development team, and so on. Second, the curriculum for environmental officials was not considered the environmental officials' readiness for education, developmental level and competency. Suggestions for future research were offered.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.18 no.1
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• pp.105-111
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• 2018

STEAM and S / W education in public education are effective in fostering talented people and the talents of the 4th industrial revolution era. It is necessary to expand the teachers for this purpose, to find out and apply various learning materials, and to improve education environment for fusion talent education. An open learning platform is effective in reducing private education costs and supplementing public education. Especially, it is useful for flip learning combined with classroom (off-line). In this case, teacher's role can be transformed into active teaching activities and research activities, which can speed up normalization of public education and reduce private education.In particular, the core functions of the MOOC platform for elementary education are 'creative instructional design and contents development function', 'digital teaching and learning curation', 'big data based learner customization', 'learning participation' flip learning and social Learning function.Through this study, it is expected that discussion on the introduction of MOOC for career and admission education for adolescents including elementary education will be established and the Korean youth MOOC platform will be developed and developed as a global advanced model of education democratization.

• Proceedings of the Korean Environmental Health Society Conference
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• 2004.12a
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• pp.88-88
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• 2004

• Journal of The Korean Association of Information Education
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• v.18 no.4
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• pp.633-644
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• 2014

In this research, focusing on the public data access function and the communication function of SNS's, an educational program was implemented for the PC and mobile environments. The program offers functionality to share short messages with friends so that problems can be solved while communicating these messages back and forth. With each visiting page, a method for communication was provided, and each room had a announcements page, Q&A section, discussion forum, and file sharing space to facilitate more communication, and by adding the 'search for friends', and 'recommended friends' functionality, it was possible to study with friends and other unknown people using the program. The applications of the educational program were proposed through the analysis of survey results of elementary and high school students of the program.