• Title/Summary/Keyword: pruritus

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Radiation recall dermatitis triggered by sorafenib after radiation therapy for hepatocellular carcinoma

  • Kim, Gwi Eon;Song, Hee-Sung;Ahn, Ki Jung;Kim, Young Suk
    • Radiation Oncology Journal
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    • v.35 no.3
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    • pp.289-294
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    • 2017
  • Sorafenib is widely used for unresectable and metastatic hepatocellular carcinomas. Radiation recall dermatitis (RRD) is an acute inflammatory reaction confined to previously irradiated skin that occurs after the administration of certain drugs. RRD after sorafenib treatment is rare; five cases have been reported thus far. We describe a 44-year-old man irradiated for chest wall bone metastasis from hepatocellular carcinoma. Eight days after radiotherapy completion, systemic therapy for metastatic hepatocellular carcinoma was initiated with sorafenib treatment. Eleven days after starting sorafenib, the patient complained of erythematous rash with pruritus in the chest wall, in a location consistent with the previous radiation field. Sorafenib was continued at the same dose, despite the RRD. The skin reaction subsided over the next 2 weeks without any medical intervention.

Clinical Application of PCR-RFLP for the Differentiation of Trichophyton mentagrophytes var. erinacei in the Facial Dermatitis of Household African Pygmy Hedgehog (Erinaceus albiventris)

  • Han, Jae-Ik;Na, Ki-Jeong
    • Journal of Veterinary Clinics
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    • v.25 no.3
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    • pp.211-214
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    • 2008
  • This report describes a case of severe and prolonged dermatophytosis in a hedgehog that was diagnosed by PCR-RFLP, a rapid and usefulness technique for identification of many causative agents and hereditary characters. A 5-month-old female hedgehog was presented with grade 2 facial pruritus, scaling, encrustation and hemorrhage. Cytology of exudates on the face showed a suspected fungal infection. A culture and tape imprint test of the cultured colony showed many hyphae and microcornidia, suspected to belong to the Trichophyton species. In the PCR-RFLP with MvaI and Hinf I, Trichophyton mentagrophytes var. erinacei was finally identified as a causative agent. The patient completely recovered after application of nystatin cream for 17 days.

Acute Dystonia Induced by Epidural Droperidol -A case report- (경막외강으로 Droperidol을 투여한 후 발생한 불수의 근수축 -증례 보고-)

  • Chae, Yoon-Jeong;Yoon, Kyung-Bong;Lim, Jae-Woo;Choi, Jae-Chan;Lee, Young-Bok
    • The Korean Journal of Pain
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    • v.13 no.2
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    • pp.255-258
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    • 2000
  • Epidural morphine is effective in the treatment of postoperative pain, but side effects, such as nausea, vomiting, pruritus and urinary retention commonly occur. Droperidol is frequently used as an antiemetic to prevent intraoperative and postoperative vomiting. But it has been reported to cause acute extrapyramidal effects including dystonia. We report one case of acute dystonia in young adult following the use of epidural droperidol.

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A Case Report of VulvoVaginal Candidiasis treated by Dahuanghuanglianxiexin-tang based on Shanghanlun provisions (『상한론(傷寒論)』 변병진단체계(辨病診斷體系)에 근거하여 대황황련사심탕(大黃黃蓮瀉心湯)을 투여한 칸디다성 질염 치험 1례)

  • Choi, Ju-Young
    • 대한상한금궤의학회지
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    • v.7 no.1
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    • pp.53-63
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    • 2015
  • Objective : This case report show the effect of Dahuanghuanglianxiexin-tang on VulvoVaginal Candidiasis. Methods : According to disease pattern identification diagnostic system based on shanghanlun provisions, The author diagnosed Taeyang-byung kyeolhyung. The symptoms of VulvoVaginal Candidiasis were worsen when the patient had long sitting position and digestive problems. Therefore the patient treated with Dahuanghuanglianxiexin-tang for 3 months. The severity of Candida Vaginitis was evaluated by patient's subjective statements(Vaginal pruritus, Vaginal secretion, Burning sensation). Results : After the treatment, Level of syptoms decreased from Severe to Trace and Eliminated. Conclusions : Dahuanghuanglianxiexin-tang improved the symptoms of VulvoVaginal Candidiasis on this study. Although Dahuanghuanglianxiexin-tang is not an usual treatment for VulvoVaginal Candidiasis, the author could prescribe the medicine due to shanghanlun six meridian patterns diagnostic system.

Two Clinical Cases study of Atopic dermatitis on the Gynecology/Pediatrics department in oriental hospital of Semyung university (세명대 한방병원 부인/소아과에 내원한 아토피성 피부염환자의 임상치험 2례 고찰)

  • Kim, Hyeong-Jun
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.20 no.2 s.33
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    • pp.247-255
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    • 2007
  • Objective : Atopic dermatitis is a chronic, inflammatory skin disease which was characterized by intense pruritus and the course marked by exacerbation and remission. The purpose of this study is to report the effect of oriental treatment. Especially new oriental prescription to atopic dermatitis Methods : We treated children patients who had atopic dermatitis and visited oriental hospital of Semyung University. Children patients in this case are two person. The first one is fourteen-years-old female, Other one is seven-years-old boy. And I create a new oriental prescription that named 'Allergy 1' thinking about oriental theory. After then I treated them with 'Allergy 1' herb medication and used two index to assess the severity in atopic dermatitis. Results : Each index show us approximately 70% improvement in atopic dermatitis symptom. Conclusion : On the basis of this cases, It may be considered that treatment of atopic dermatitis should be improved by the treatment of herb medication "Allergy 1"

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Pharmacognostical Studies on the 'BaegDuOng' (백두옹의 생약학적 연구)

  • Bae, Ji-Yeong;Jeon, Un-Jin;Park, Jong-Hee
    • Korean Journal of Pharmacognosy
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    • v.42 no.1
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    • pp.6-8
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    • 2011
  • 'BaegDuOng(白頭翁)' is one of the Chinese crude drugs used mainly as a pruritus, arthritis, cough and abdominal pain. The botanical origin of the crude drug has never been studied pharmacognostically. To clarify the botanical origin of 'BaegDuOng', the morphological and anatomical characteristics of Pulsatilla species growing in Korea, i.e. Pulsatilla koreana Nakai and P. cernua (Thunb.) Spreng. were studied. As a result, BaegDuOng from Korea was proved to be the root of Pulsatilla koreana.

A study on the Severity Scoring Systems of Atopic Dermatitis ; Comparision, Analysis and Establishment (아토피 피부염의 평가방법에 대한 연구 : 비교 분석 및 설립)

  • 윤화정;윤정원;윤소원;고우신
    • The Journal of Korean Medicine
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    • v.23 no.4
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    • pp.15-26
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    • 2002
  • There is much confusion in the field of atopic dermatitis (AD) regarding how to best measuredisease severity objectively. Therefore, we aimed to establish a new adequate scoring system for AD, that should be based on comparisonand analysis of various scoring systems. We report as follows. Methods: We searched for data relating to severity scoring systems for atopic dermatitis in Entrez PubMed From 1990 to 2001 Results and Conclusions: 1. Properties of severity scoring systems were validity, reliability, sensitivity of change and ease of use. 2. The essential items of severity scoring systems were extent. intensity and subjective symptoms. 3. The surface extent of the lesion was evaluated by the percentage of involvement of each of 10 areas. 4. The criteria of severity were divided into intensity and subjective symptoms. Intensity items are erythema, papulation, lichenification, oozing, dryness, excoriations, and pigmentation. The subjective symptom is pruritus, evaluated according to sleep loss. 5. The significant items of severity scoring system were symptomsrather than areas. As it were, we assumed extent accounted for around 30% of each total score, with intensity and subjective symptoms representing 70%.

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A Clinical Study on the Case of Nummular Eczema Treated with Bamboo Salt Pharmacopuncture and Herbal Medicine (화폐상 습진에 한약복용과 함께 죽염약침을 적용한 치험례)

  • Shin, Jung-Mi;Kang, Mi-Suk
    • Journal of Acupuncture Research
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    • v.25 no.6
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    • pp.175-182
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    • 2008
  • Objectives : The purposes of this study are to investigate the efficacy of bamboo salt pharmacopuncture on nummular eczema. Methods : The patient was treated by bamboo salt pharmacopuncture and herbal medication. The improvement of the symtoms was evaluated by The SCORAD Index. Results : After treatment, erythema and pruritus were significantly improved. The SCORAD Index changed from 60.2 to 10.1. Conclusions : It is suggested that bamboo salt pharmacopuncture is effective on nummular eczema.

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The peripheral and central mechanisms underlying itch

  • Lee, Jae Seung;Han, Jasmin Sanghyun;Lee, Kyeongho;Bang, Juwon;Lee, Hyosang
    • BMB Reports
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    • v.49 no.9
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    • pp.474-487
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    • 2016
  • Itch is one of the most distressing sensations that substantially impair quality of life. It is a cardinal symptom of many skin diseases and is also caused by a variety of systemic disorders. Unfortunately, currently available itch medications are ineffective in many chronic itch conditions, and they often cause undesirable side effects. To develop novel therapeutic strategies, it is essential to identify primary afferent neurons that selectively respond to itch mediators as well as the central nervous system components that process the sensation of itch and initiate behavioral responses. This review summarizes recent progress in the study of itch, focusing on itch-selective receptors, signaling molecules, neuronal pathways from the primary sensory neurons to the brain, and potential decoding mechanisms based on which itch is distinguished from pain.

One Case of Atopic Dematitis Treated by Horminis Placenta External Wet Therapy (자하거(紫河車) 습포요법(濕布療法)을 이용한 아토피 환자 치험 1 례)

  • Park, Eun-Seong;Lee, Jin-Young
    • The Journal of Pediatrics of Korean Medicine
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    • v.24 no.1
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    • pp.46-56
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    • 2010
  • Objectives The purpose of this study is to report a Atopic dematitis patient treated by Horminis Placenta external wet therapy. Methods The patient was treated by acupuncture, herb medicine, especially Horminis Placenta external therapy. Kunz type, SCORAD index and Vas scale were used to measure the progression. Results and Conclusions We had evaluated the score during admission. SCORAD index include the extent, the intensity, pruritus, sleeping loss had increased from 52.88 score to 21.26 score. And the symptoms had improved with treatment.