• 제목/요약/키워드: production stability

검색결과 1,351건 처리시간 0.031초

형질전환된 담배세포배양을 이용한 hGM-CSF 생산에서 여러 가지 단백질 안정제가 미치는 영향 (Effects of Various Stabilizers on the Production of hGM-CSF in Transgenic Nicotiana tabacum Suspension Cell Cultures)

  • 조종문;김동일
    • KSBB Journal
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    • 제22권4호
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    • pp.185-190
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    • 2007
  • Productivity of secreted recombinant protein depends largely on its stability in the extracellular environment with protease. Most hGM-CSF produced by transgenic tobacco cell cultures and secreted to the medium was confirmed to be rapidly degraded by protease in medium. To increase the productivity, therefore, various protein stabilizers such as gelling agents such as carrageenan and alginate, polymers, polyols, and amino acids have been tested. The stability of hGM-CSF in spent medium without cells was improved by the presence of gelling agents. However, the reason for the enhanced production by the addition of gelling agents may be due to the increased expression level and permeability rather than stability. The addition of DMSO inhibited the cell growth, but improved specific yield. The others were not effective for stability as well as hGM-CSF production.

생산(生産) - 재고관리(在庫管理) 시스템의 동적거동(動的擧動)에 관한 연구(硏究) (A Study of Dynamic Behavior of Production - Inventory Control System)

  • 김만식;박용선
    • 대한산업공학회지
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    • 제5권1호
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    • pp.1-6
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    • 1979
  • This paper discusses an application of discrete variable Servo Theory to the analysis of the effectiveness of production-inventory control system which uses exponential smoothing as a specific forecasting technique by establishing a new model which consists of such three departments as production planning, production, and inventory. The objective of the new production-inventory model is to keep the production to the optimal level of minimum production cost in production planning problem for obtaining, the stability of inventory subject to demand variation. On this basis, the dynamic characteristic of the system with the change of the parameters is clarified by the numerical analysis. The results of the numerical analysis show the effect that is obtained by the simultaneous stability of production and inventory as soon as possible.

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Investigation of Influence of Pulse-periodical Laser Radiation Power on Stability of Liquid-metal Contacts between Powder Particles during Selective Laser Sintering

  • Beljavin, K.E.;Minko, D.V.;Bykov, R.P.;Kuznechik, O.O.
    • 한국분말야금학회:학술대회논문집
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    • 한국분말야금학회 2006년도 Extended Abstracts of 2006 POWDER METALLURGY World Congress Part 1
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    • pp.518-519
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    • 2006
  • A connection between pulse-periodical laser radiation power and stability of liquid-metal contacts between powder particles during selective laser sintering (SLS) is determined based on analysis solving the problem of stability of liquid column in the gravity and capillary forces field. On the grounds of obtained relationships the optimization of pulse-periodical laser radiation power and SLS-process duration is realized, that allows to produce voluminous powder porous materials with pre-determined physical and mechanical properties and surface geometry. Results of metallographic investigations of powder porous materials of titanium powder produced with technological regimes calculated by means of obtained relationships are given in the work

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생활계 폐합성수지 물질 재활용 제품의 생산시기별 품질 특성 (Quality Characteristics According to the Production Period of Products Obtained by Recycling Household Plastic Waste Materials)

  • 강혜주;신성철;강석표
    • 한국건축시공학회:학술대회논문집
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    • 한국건축시공학회 2020년도 가을 학술논문 발표대회
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    • pp.167-168
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    • 2020
  • In order to expand the material recycling of waste plastics made of composite materials, it is necessary to develop the use of material recycling products and to secure their quality stability. In this paper, as a basic study to secure the stability of the quality of household waste plastic material recycling products, the quality characteristics of recycled materials according to the production period were compared and reviewed. In addition, the average tensile strength of the recycled products by production period for 4 months was 12.33 MPa, and the average density was 1.35 g/m3.

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감압법을 이용한 가스 생산 시 하이드레이트 부존 퇴적층의 지반 안정성 및 가스 생산성에 대한 시추 공저압 및 감압 속도의 영향 (Effect of Bottom Hole Pressure and Depressurization Rate on Stability and Gas Productivity of Hydrate-bearing Sediments during Gas Production by Depressurization Method)

  • 김정태;강석준;이민형;조계춘
    • 한국지반공학회논문집
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    • 제37권3호
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    • pp.19-30
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    • 2021
  • 선행 연구를 통해 우리나라 동해 울릉 분지에 천연가스 자원인 하이드레이트 부존 퇴적층의 존재가 확인되었다. 퇴적층에서 가스를 생산하기 위한 시도는 세계적으로 연구되고 있으며, 생산 메커니즘은 열-수리-역학적 현상이 동시에 발생하는 복합적인 현상이다. 하이드레이트의 생산성 및 안정성 평가는 실험실 규모로 수행되기에는 어려움이 있다. 따라서, 가스 하이드레이트의 생산성 및 퇴적층의 안정성 평가를 위해서는 전산 수치 해석이 필수적으로 수행되어야 한다. 이 연구에서는 여러 가지 가스 하이드레이트 생산 방법 중 감압법을 이용한 생산 시 목표 공저압 및 감압속도에 따른 하이드레이트 퇴적층의 안정성과 가스 생산성에 대한 영향을 전산 모사 해석을 통해 분석하였다. 연구결과 목표 공저압이 낮을수록 생산성은 향상되고 안정성은 악화되는 것을 확인하였고, 감압 속도는 가스 생산성 및 퇴적층의 안정성에 큰 영향을 미치지 않는 것을 확인할 수 있었다. 추가적으로 실제 시험 생산 시 발생할 수 있는 사질생산 현상에 대한 대응 전략 수립을 위해 감압 속도 조절에 따른 가스 생산성 및 퇴적층의 안정성 평가 해석을 수행하였다. 해석 결과 낮은 감압 속도에서 높은 감압 속도로 변경 시킬 경우 안정성 확보에 효과가 있음을 확인하였다. 또한, 가스 생산 시 하이드레이트 해리로 인한 퇴적층의 침하가 발생하고 시추 생산정 하부에서는 압력 구배로 인해 지반 융기가 발생하는 것을 확인하였다. 이 결과를 통해 감압법을 활용한 가스 생산 시 목표 공저압 선정을 위해서는 생산성 및 안정성에 대한 고려가 동시에 수행되어야 하며, 지반 변위로 인해 생산 시추공에 발생하는 응력에 대한 고려도 필수로 수행되어야 한다는 결론을 얻었다.

대장균을 이용한 Phenylalanine 생산에 있어서 온도조절형 발현 Vector의 안정성 (Phenotypic Stability of a Temperature-Controllable Expression Vector on Phenylalanine Production by Escherichia coli)

  • 강상모;박인숙
    • 한국미생물·생명공학회지
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    • 제19권5호
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    • pp.433-438
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    • 1991
  • Phenylalanine 고생산용 plasmid pSY130-14는 $\lambda$-phage 유래 온도감수성을 가지고 있으므로 $cI_{857}$ repressor와 PL과 PR을 온도를 올려 phenylalanine의 생산을 유도한다. pSY130-14를 갖는 E.coli AT2471은 kanamycin 무첨가, $38.5^{\circ}C$, 48시간에서 약 30%로 plasmid가 없어지며 첨가에서 안정성이 떨어졌다가 배양시간과 더불어 올라갔는데, 이것은 생육에 피요한 kanamycin gene과 ori만이 남는 것으로 생각된다.

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생산 방식별 재생 잔골재의 품질에 대한 기초적 연구 (A Study on the Quality Improvement of Recycled Fine Aggregates with Production Methods)

  • 심종우;이세현;유명열;이문환;송태협
    • 한국콘크리트학회:학술대회논문집
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    • 한국콘크리트학회 2004년도 춘계 학술발표회 제16권1호
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    • pp.368-371
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    • 2004
  • It analyzes the quality of the fine aggregate which is reproduced through a dry production process with cyclone and a wet production process. The conclusions of the study are as follows. 1. The recycled fine aggregate through the dry production process with cyclone shows the low rate of absorption and impurity content after the cyclone process. It shows that its density is 2.37, absorption rate is 4.8 and stability is $5.1\%$ and less. Therefore, it satisfies the standards of KS F 2573(recycled aggregate for concrete) as the first grade. 2. The recycled fine aggregate through the wet production process shows the low rate of absorption and foreign substance content after the process of wash and dehydration. It shows that its density is 2.40, absorption rate is 3.12 and stability is $3.2\%$ and less. Therefore, it satisfies the standards of KS F 2573(recycled aggregate for concrete) as the first grade.

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Production system influences color stability and lipid oxidation in gluteus medius muscle

  • Ana Paula Amaral de Alcantara Salim;Micheli da Silva Ferreira;Maria Lucia Guerra Monteiro;Loise Caroline Santos de Lima;Isabelle Trezze Marins Magalhaes;Carlos Adam Conte-Junior;Sergio Borges Mano
    • Animal Bioscience
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    • 제36권5호
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    • pp.785-796
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    • 2023
  • Objective: We aimed to evaluate the color and oxidative stability of beef gluteus medius (GM) from cattle raised in organic and non-organic production systems. Methods: The GM samples (n = 10) were obtained from organic (ORG; n = 5) or nonorganic (NORG; n = 5) beef samples, sliced into 2.54-cm steaks, packaged in aerobic conditions, and stored for nine days at 4℃. ORG and NORG steaks were compared regarding myoglobin concentration, pH, instrumental color, delta E (ΔE), metmyoglobin reducing activity (MRA), and lipid oxidation on days 0, 5, and 9. Results: Feeding system did not influence (p>0.05) the myoglobin concentration. ORG steaks exhibited greater (p<0.05) meat pH, yellowness, and MRA, whereas NORG steaks exhibited greater (p<0.05) redness, chroma, R630/580, delta E, and lipid oxidation. ORG and NORG steaks exhibited similar (p>0.05) lightness and hue angle. During storage, ORG and NORG exhibited an increase in muscle pH, hue angle, and lipid oxidation; and a decrease (p<0.05) in redness, yellowness, chroma, and color stability (R630/580). Both samples exhibited a stable (p>0.05) pattern for lightness and MRA. Conclusion: Therefore, the production system can affect beef color and lipid stability during storage.

Stability and failure of symmetrically laminated plates

  • Chai, Gin Boay;Hoon, Kay Hiang;Chin, Sin Sheng;Soh, Ai Kah
    • Structural Engineering and Mechanics
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    • 제4권5호
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    • pp.485-496
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    • 1996
  • This paper describes a numerical and experimental study on the stability and failure behaviour of rectangular symmetric laminated composite plates. The plates are simply supported along the unloaded edges and clamped along the loaded ends, and they are subjected to uniaxial in-plane compression. The finite element method was employed for the theoretical study. The study examines the effect of the plate's stacking sequence and aspect ratio on the stability and failure response of rectangular symmetric laminated carbon fibre reinforced plastics composite plates. The study also includes the effect of the unloaded edge support conditions on the postbuckling response and failure of the plates. Extensive experimental investigation were also carried out to supplement the finite element study. A comprehensive comparison between theory and experimental data are presented and discussed in this contribution.

Nexus between Production Input and Price Commodity: An Integration Analysis of Rice Barns in East Java of Indonesia

  • WULANDARI, Dwi;NARMADITYA, Bagus Shandy;PRAYITNO, Putra Hilmi;ISHAK, Suryati;SAHID, Sheerad;QODRI, Lutfi Asnan
    • The Journal of Asian Finance, Economics and Business
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    • 제7권10호
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    • pp.451-459
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    • 2020
  • This study aims to examine the causality between production input and the price of rice in East Java, Indonesia. This study applied a quantitative method to understand in a comprehensive way the correlation between variables. The data used for this study were collected from several sources, including East Java Agriculture Office, Siskaperbapo.com, and Statistics Indonesia (BPS) of East Java. This research was carried out over five years, starting from 2014 to 2018. Furthermore, the data were analyzed using the Vector Error Correction Model (VECM) by employing E-Views (version 7). The findings of this study indicated that, in the long run, the population, rice production, and changes in people's income have a positive effect on price stability, but are inversely proportional if seen in the short term. In comparison, in the long run, farmer exchange rates variable has a negative impact on price stability, and inversely proportional in the short term, which has a positive effect. There are different implications when the people's income increases and the rice price declines; these have great potential to alleviate poverty in East Java, Indonesia. This is due to the fact that the price stability also concerns the welfare of the community.