• Title/Summary/Keyword: production costs

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정상 인체 세포로부터 조직 플라스미노겐 활성인자의 대량생산 (The Production of Tissue Type Plasminogen Activator from Normal Human Cell tine)

  • Lee, Hyeon-Yong;Kim, Geum-Soo
    • 한국미생물·생명공학회지
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    • 제16권6호
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    • pp.522-525
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    • 1988
  • 무혈청 배지에 생산촉진제로 30$\mu$g/m$\ell$의 Heparin 을 첨가해 정상인의 섬유 세포로부터 상업적으로 tPA를 생산할 수 있는 방법의 개발과, 효과적인 tPA 생산을 위해 대량 배양에 적합한 무혈청 배지의 조성을 확립했다. 이 방법으로 연속배양 공법하에서 매일 1.1gram의 tPA가 생산될 수 있으며, 이 생산성은 tPA 생산 단가를 크게 낮출 분만 아니라 무혈청 배지의 사용으로 tPA의 순수 정제 과정을 크게 단축시킬 수 있다. 또한 이 세포에서 생산되는 tPA 는 fibrin lysis 시험결과 섬유질 분해능력이 높음이 입증되었으며, ELISA결과와도 상충했다.

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신기술 수용농가의 시범사업 타당성 및 경영성과 분석 (An analysis on the propriety of pilot project and the Management Performance in Korea's new technology adaptation Farming)

  • 김연중;한혜성
    • 한국산학기술학회논문지
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    • 제16권9호
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    • pp.5859-5864
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    • 2015
  • 본 연구는 농촌진흥청에서 기술시범사업으로 추진하고 있는 마늘주아재배 기술 사업에 대하여 농업경영체의 신기술 수용에 대한 태도, 신기술의 타당성 분석, 기술도입 전후의 경영효과를 분석하는데 그 목적이 있다. 마늘주아재배 농가들은 농업 신기술에 대한 요인들 중 기술만족도(4.30)가 가장 높았으며, 그 다음 새로운 것을 적극적으로 선호하고자 하는 혁신성(4.21) 순으로 나타났다. 반면에 신기술에 대한 위험에 대해서는 관대한 것으로 나타났다. 한편, BMO 모델을 이용하여 마늘 주아재배 기술 사업에 대한 타당성을 평가한 결과에 따르면, 사업 매력도와 적사도가 각각 44점, 45점으로 사업 성공률이 80%이상으로 높았다. 마늘주아 재배기술의 도입 전후의 경영성과 분석에서도 이 사업 참여 농가들은 신기술을 도입 한 후 종구비 절감(43%) 및 수량증가(28%) 등 전반적으로 경영이 개선된 것으로 나타났다.

방열판 직접압출공정의 성형성 향상에 관한 연구 (A Study on Improvement of Extrudability for Extrusion Process of Heat Sink)

  • 이정민;김병민;강충길
    • 소성∙가공
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    • 제13권5호
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    • pp.422-428
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    • 2004
  • At present, the design of extrusion dies and operation in extrusion companies are primarily based on trial and error. The experience of the die designer, the press operator and the die corrector determine the performance of the extrusion die and the efficiency of the process. In order to produce defect-free products of desirable quality in terms of strength, surface quality and geometrical dimensions, it is important to obtain more knowledge of the processes that occur during extrusion. Recently, to reduce the costs of designing and manufacturing of extrusion dies, and to ensure the quality of the extruded products, numerical simulation for extrusion processes such as FEM (finite element method) is applied increasingly and becomes a very important tool for the design and development of new products. However, most of the studies about FE simulation have been accomplished for simple geometry and low extrusion ratio in the filed of steady metal flow conditions. The extruded products of AI alloy in industrial practice involve complicated sectional geometry. This study was designed to reduce the time of die design and manufacturing in the extrusion process using FEM simulation. FEM simulations of extrusion process were performed in non-steady states conditions by changing weld plate included in extrusion die set. Product which was employed in this study is heat sink that has been used in the parts of heat exchanger of electric circuits. It is generally applied for aluminum or its alloys due to heat efficiency and easy production of complicated shapes, and manufactured by extrusion process. The simulated results showed that weld plate shape in extrusion dies influences meta] flow and dimensional accuracy of products.

Accuracy Estimation of Electro-optical Camera (EOC) on KOMPSAT-1

  • Park, Woon-Yong;Hong, Sun-Houn;Song, Youn-Kyung
    • Korean Journal of Geomatics
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    • 제2권1호
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    • pp.47-55
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    • 2002
  • Remote sensing is the science and art of obtaining information about an object, area or phenomenon through the analysis of data acquired by a device that is not in contact with the object, area, or phenomenon under investigation./sup 1)/ EOC (Electro -Optical Camera) sensor loaded on the KOMPSAT-1 (Korea Multi- Purpose Satellite-1) performs the earth remote sensing operation. EOC can get high-resolution images of ground distance 6.6m during photographing; it is possible to get a tilt image by tilting satellite body up to 45 degrees at maximum. Accordingly, the device developed in this study enables to obtain images by photographing one pair of tilt image for the same point from two different planes. KOMPSAT-1 aims to obtain a Korean map with a scale of 1:25,000 with high resolution. The KOMPSAT-1 developed automated feature extraction system based on stereo satellite image. It overcomes the limitations of sensor and difficulties associated with preprocessing quite effectively. In case of using 6, 7 and 9 ground control points, which are evenly spread in image, with 95% of reliability for horizontal and vertical position, 3-dimensional positioning was available with accuracy of 6.0752m and 9.8274m. Therefore, less than l0m of design accuracy in KOMPSAT-1 was achieved. Also the ground position error of ortho-image, with reliability of 95%, is 17.568m. And elevation error showing 36.82m was enhanced. The reason why elevation accuracy was not good compared with the positioning accuracy used stereo image was analyzed as a problem of image matching system. Ortho-image system is advantageous if accurate altitude and production of digital elevation model are desired. The Korean map drawn on a scale of 1: 25,000 by using the new technique of KOMPSAT-1 EOC image adopted in the present study produces accurate result compared to existing mapping techniques involving high costs with less efficiency.

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테르밋 반응을 이용하여 금속실리콘을 추출할 때 규석 순도에 따라 금속실리콘 순도 변화에 대한 고찰 (A Study on the Purity Change of Silicon Metal According to the Purity of Silica Stone in Metal Silicon Extraction by Thermit Reaction)

  • 김재희;한진호;신현명
    • 자원리싸이클링
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    • 제26권4호
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    • pp.19-25
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    • 2017
  • 금속실리콘을 제조하는 방법에는 탄소환원법, 플라즈마환원법, 테르밋반응 등이 있다. 상업용 금속실리콘을 대량 생산하는 방법으로 탄소환원법에 의한 아크전기로가 일반적으로 많이 사용되고 있다. 아크전기로를 이용한 생산시스템이 극복해야 할 문제로는 제조원가 중 전력비 비율이 30%를 차지할 정도로 높은 전기에너지 비용과 환경방지 시설구축 및 유지관리비용이다. 이러한 이유로 국내에서는 아직 아크전기로를 이용한 생산시스템이 상용화 제조시스템으로 구축되지 못하고 있다. 기업 및 연구기관에서 탄소환원법의 아크전기로를 이용하여 최적 생산시스템을 연구하고 있다. 세 가지 유형의 이산화규소를 테르밋반응을 통하여 순도변화를 알 수 있었다. 그리고 실험분석에서 테르밋반응을 사용하여 이산화규소 순도로 금속실리콘 순도 변화를 분석하였다. 이산화규소 순도와 금속실리콘 순도는 밀접한 관계가 있음을 알 수 있었다.

비용기반 스케쥴링 : Part I, 작업내 비용 전파알고리즘 (Cost-Based Directed Scheduling : Part I, An Intra-Job Cost Propagation Algorithm)

  • 김재경;서민수
    • 지능정보연구
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    • 제13권4호
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    • pp.121-135
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    • 2007
  • 문제의 제약조건을 명확히 표현하고 휴리스틱 탐색에 의하여 스케쥴링을 형성하는 제약조건 중심의 스케쥴링 기법은 실세계의 스케쥴링 문제에 성공적으로 적용되어 왔다. 하지만, 기존의 제약조건 중심의 스케쥴링 연구에서 스케쥴링의 목적을 표현하고 최적화하는데 관련된 연구는 부족한 상황이다. 특히 비용 목적함수는 다양한 비즈니스 계획의 효과를 분석하는 기업의사결정에서 매우 중요 하다고 평가된다. 이 연구의 목적은 자원 용량이나 일시적인 제약조건을 만족하면서 지연비용 및 재고비용을 포함한 스케쥴링의 전체 비용을 명확하게 표현하고 최적화하는 것이다. 비용기반 스케쥴링 프레임워크에서, 동일한 작업 내에 일시적인 제약조건을 만들어 가면서 비용함수를 개선해 나가는 비용 전파 알고리즘을 제시하였다.

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A Study on the Dynamic Analysis of Mooring System During Hook-up Installation

  • Lee, Min Jun;Jo, Hyo Jae;Lee, Sung Wook;Hwang, Jea Hyuk;Kim, Jea Heui;Kim, Young Kyu;Baek, Dong Il
    • 한국해양공학회지
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    • 제34권5호
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    • pp.285-293
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    • 2020
  • This study evaluated the Hook-up installation of an offshore site construction process, which is the final step in an offshore site installation process. During Hook-up installation, the offshore structure can have a detrimental effect on the work stability due to low-frequency motion. Moreover, economic costs can be incurred by the increase in available days of a tugboat. Therefore, this study developed a numerical analysis program to assess the dynamic behavior of mooring systems during hook-up installation to analyze the generally performed installation process and determine when the tugboat should be released. In this program, the behavior of an offshore structure was calculated using Cummin's time-domain motion equation, and the mooring system was calculated by Lumped mass method (LMM). In addition, a tugboat algorithm for hook-up installation was developed to apply the Hook-up procedure. The model used in the calculations was the barge type assuming FPSO (Floating production storage and off-loading) and has a taut mooring system connected to 16 mooring lines. The results of the simulation were verified by comparing with both MOSES, which is a commercial program, and a calculation method for restoring coefficient matrix, which was introduced by Patel and Lynch (1982). Finally, the offset of the structure according to the number of tugboats was calculated using the hook-up simulation, and the significant value was used to represent the calculation result.

Insect Repellency and Crop Productivity of Essential Oil Films

  • KIM, Jin Gu;KANG, Seok Gyu;MOSTAFIZ, Md Munir;LEE, Jeong Min;LEE, Kyeong-Yeoll;HWANG, Tae Kyung;LIM, Jin Taeg;KIM, Soo Yeon;LEE, Won Hee
    • Journal of the Korean Wood Science and Technology
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    • 제48권1호
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    • pp.95-106
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    • 2020
  • The purpose of this study was to determine the effects of coniferous essential oils (EOs) blended films on insect repellence and crop productivity. Low-density polyethylene (LDPE) film is widely used, especially in agriculture and for food packaging. Ethylene vinyl acetate was blended with LDPE to reduce volatilization of EOs. An EO from Japanese cypress (Chamaecyparis obtusa) was incorporated into the blend film to conduct field research on antimicrobial and insect repellent properties. Among the various concentrations of EO, the highest concentration (2.5%) showed the highest efficiency in terms of pesticidal activity. The ability to inhibit microbial growth can be explained by the lipophilic properties of the EO component, and many studies have already demonstrated this. Agricultural films containing all types of EO have been tested on various crops such as chili, cucumber, Korean melon and have been able to verify their effectiveness in avoiding pests and increasing yields. From these results, it was found that it is reasonable to use a modified film such as a composite film containing an EO for agriculture. Thus, the modified film containing EO has undoubtedly shown impressive potential for reducing the use of pesticides in a variety of ways, not only for agricultural mulching film but also for food and agricultural product packaging. This product is an environmentally friendly chemical and is safe for agricultural and industrial and food packaging applications, among others. In particular, the use of agricultural films significantly reduces the use of pesticides, suggesting that farmers can increase their incomes by reducing working hours and costs, and increasing production.

영상정보를 이용한 가스벤트자동교환 장치 (A study on the development of Gas-Vent Automatic Exchange Machine with Vision System)

  • 권장우;홍준의;윤동업;길경석;이동훈;노태정
    • 한국정보통신학회논문지
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    • 제11권6호
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    • pp.1141-1149
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    • 2007
  • 본 논문에서는 신발금형의 가스벤트 착탈 작업을 효율적으로 진행하기 위해 이미지 프로세싱을 통한 가스벤트 착탈위치 탐색과 정밀 제어로 착탈 작업을 수행하는 교환 장치의 두 가지 기술을 다루고 있다. 이 두가지 방법을 적용하기 위한 핵심적인 이슈는 신발 금형의 가스벤트 교환 위치의 중심을 어떻게 하면 정확하게 찾아내는가이다. 이러한 자동 교환 장치의 사용은 가스벤트 착탈 시간을 줄이며 아울러 노동력의 절감 제품의 생산에 드는 비용을 최소화하는 등의 여러 가지 이점을 가져다 준다. 이 장치를 사용하여 실험을 통해 검증한 결과 가스벤트 교환 장치의 사용이 더 안정적이고 효율적이며 착탈 시간을 줄여 공정시간을 단축하는 것을 증명할 수 있었다.

Experimental investigation on the effect of cementitious materials on fresh and mechanical properties of self-consolidating concrete

  • Shariati, Mahdi;Rafie, Shervin;Zandi, Yousef;Fooladvand, Rouhollah;Gharehaghaj, Behnam;Mehrabi, Peyman;Shariat, Ali;Trung, Nguyen Thoi;Salih, Musab N.A.;Poi-Ngian, Shek
    • Advances in concrete construction
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    • 제8권3호
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    • pp.225-237
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    • 2019
  • Although applying self-consolidating concrete (SCC) in many modern structures is an inevitable fact, the high consumption of cement in its mixing designs has led to increased production costs and adverse environmental effects. In order to find economically viable sources with environmentally friendly features, natural pozzolan pumice and blast furnace slag in 10-50% of replacement binary designs have been investigated for experiments on the properties of fresh concrete, mechanical properties, and durability. As a natural pozzolan, pumice does not require advanced equipment to prepare for consumption and only needs to be powdered. Pumice has been the main focus of this research because of simple preparation. Also to validate the results, in addition to the control specimens of each design, fly ash as a known powder has been evaluated. Moreover, ternary mixes of pumice and silica fume were investigated to enhance the obtained results of binary mixes. It was concluded that pumice and slag powders indicated favorable performance in the high percentage of replacement.