• Title/Summary/Keyword: pressure management

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The Unique Relationship between Neuro-Critical Care and Critical Illness-Related Corticosteroid Insufficiency : Implications for Neurosurgeons in Neuro-Critical Care

  • Yoon Hee Choo;Moinay Kim;Jae Hyun Kim;Hanwool Jeon;Hee-Won Jung;Eun Jin Ha;Jiwoong Oh;Youngbo Shim;Seung Bin Kim;Han-Gil Jung;So Hee Park;Jung Ook Kim;Junhyung Kim;Hyeseon Kim;Seungjoo Lee
    • Journal of Korean Neurosurgical Society
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    • v.66 no.6
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    • pp.618-631
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    • 2023
  • The brain houses vital hormonal regulatory structures such as the hypothalamus and pituitary gland, which may confer unique susceptibilities to critical illness-related corticosteroid insufficiency (CIRCI) in patients with neurological disorders. In addition, the frequent use of steroids for therapeutic purposes in various neurological conditions may lead to the development of steroid insufficiency. This abstract aims to highlight the significance of understanding these relationships in the context of patient care and management for physicians. Neurological disorders may predispose patients to CIRCI due to the role of the brain in hormonal regulation. Early recognition of CIRCI in the context of neurological diseases is essential to ensure prompt and appropriate intervention. Moreover, the frequent use of steroids for treating neurological conditions can contribute to the development of steroid insufficiency, further complicating the clinical picture. Physicians must be aware of these unique interactions and be prepared to evaluate and manage patients with CIRCI and steroid insufficiency in the context of neurological disorders. This includes timely diagnosis, appropriate steroid administration, and careful monitoring for potential adverse effects. A comprehensive understanding of the interplay between neurological disease, CIRCI, and steroid insufficiency is critical for optimizing patient care and outcomes in this complex patient population.

Identification of an effective and safe bolus dose and lockout time for patient-controlled sedation (PCS) using dexmedetomidine in dental treatments: a randomized clinical trial

  • Seung-Hyun Rhee;Young-Seok Kweon;Dong-Ok Won;Seong-Whan Lee;Kwang-Suk Seo
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.24 no.1
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    • pp.19-35
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    • 2024
  • Background: This study investigated a safe and effective bolus dose and lockout time for patient-controlled sedation (PCS) with dexmedetomidine for dental treatments. The depth of sedation, vital signs, and patient satisfaction were investigated to demonstrate safety. Methods: Thirty patients requiring dental scaling were enrolled and randomly divided into three groups based on bolus doses and lockout times: group 1 (low dose group, bolus dose 0.05 ㎍/kg, 1-minute lockout time), group 2 (middle dose group, 0.1 ㎍/kg, 1-minute), and group 3 (high dose group, 0.2 ㎍/kg, 3-minute) (n = 10 each). ECG, pulse, oxygen saturation, blood pressure, end-tidal CO2, respiratory rate, and bispectral index scores (BIS) were measured and recorded. The study was conducted in two stages: the first involved sedation without dental treatment and the second included sedation with dental scaling. Patients were instructed to press the drug demand button every 10 s, and the process of falling asleep and waking up was repeated 1-5 times. In the second stage, during dental scaling, patients were instructed to press the drug demand button. Loss of responsiveness (LOR) was defined as failure to respond to auditory stimuli six times, determining sleep onset. Patient and dentist satisfaction were assessed before and after experimentation. Results: Thirty patients (22 males) participated in the study. Scaling was performed in 29 patients after excluding one who experienced dizziness during the first stage. The average number of drug administrations until first LOR was significantly lower in group 3 (2.8 times) than groups 1 and 2 (8.0 and 6.5 times, respectively). The time taken to reach the LOR showed no difference between groups. During the second stage, the average time required to reach the LOR during scaling was 583.4 seconds. The effect site concentrations (Ce) was significantly lower in group 1 than groups 2 and 3. In the participant survey on PCS, 8/10 in group 3 reported partial memory loss, whereas 17/20 in groups 1 and 2 recalled the procedure fully or partially. Conclusion: PCS with dexmedetomidine can provide a rapid onset of sedation, safe vital sign management, and minimal side effects, thus facilitating smooth dental sedation.

An Empirical Study on the Adoption of Online Direct Marketing in Agricultural Firms (농업경영체의 온라인 직거래 마케팅 수용에 관한 실증적 연구)

  • Cheolho Yoon;Changhee Park
    • Information Systems Review
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    • v.20 no.1
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    • pp.41-59
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    • 2018
  • This study analyzed the factors that affect acceptance of online direct marketing in agricultural companies. Empirical analysis was conducted using the research model based on the individual's technology acceptance model (TAM) and the information technology adoption models in organizations. These models have four dimensions: 1) technology characteristics, which include perceived usefulness and perceived ease of use of TAM 2) CEO characteristics, which including the innovativeness and IT capability of CEOs; 3) organizational readiness, which include financial, technological, and human resources capabilities and 4) environment and external pressure, which include government support and changes to the Internet environment. These concepts were empirically tested. A total of 209 valid data were collected through questionnaires and analyzed using confirmatory factor analysis and path analysis through the application of structural equation modeling. Results show that perceived usefulness, IT capability of CEOs, and changes to the Internet environment have significant effects on the adoption intention of online direct marketing. However, perceived ease of use, CEO innovativeness, government support, and the variables of organizational readiness dimension did not have significant effects on adoption intention. This study suggests practical implications for adoption of online direct marketing in agricultural companies.

The Effect of Technostress on User Resistance and End-User Performance (테크노스트레스가 사용자 저항과 성과에 미치는 영향)

  • Kyoung-June Kim;Ki-Dong Lee
    • Information Systems Review
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    • v.19 no.4
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    • pp.63-85
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    • 2017
  • Recent information technology achieves remarkable progress in almost all areas where it can be applied. However, this technology also causes technostress, such as fear and pressure to individuals, due to events, such as the threat of job loss. This technostress is becoming an important factor that can affect user performance and productivity in future society where information technology will be the focus. This kind of stress should be studied considerably in academic and practical applications. The effects of technostress on individual performance remain ambiguous. Therefore, academic research is needed to prove these effects. This study aimed to clarify the direct and indirect effects of technostress on information technology end-users. We developed a research model that integrates innovation resistance and technostress theory through previous studies and analyzed the questionnaire of 317 people. The PLS structural equation model and the study results of Baron and Kenny (1986) indicated that rapid change, connectivity, reliability, and complexity are crucial factors affecting the technostress of information technology. Technostress was analyzed indirectly only through innovation resistance, which affected the performance of end-users. This study will provide new implications for the relationship between technostress and performance or productivity in the IS field.

Division of Soil Properties in Reclaimed Land of the Mangyeong and Dongjin River Basin and Their Agricultural Engineering Management (만경강과 동진강 유역 간척농경지 토양특성 구분과 농공학적 관리 대책)

  • Hwang, Seon-Woong;Kang, Jong-Gook;Lee, Kyung-Do;Lee, Kyung-Bo;Park, Ki-Hun;Chung, Doug-Young
    • Korean Journal of Soil Science and Fertilizer
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    • v.45 no.3
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    • pp.444-450
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    • 2012
  • The physical and chemical properties of soil in the Mangyeong and Dongjin river basin had been investigated in order to establish the most optimum soil improvement plan on the reclaimed land. The total soil area by reclamation in Saemangeum basin is 113,971 ha. The classification by the distribution of soil series and soil texture is as following. 13 soil series including Chonnam, Buyong and Chonbuk series are period-unknown areas. Regarding the soil texture, they are fine silty ~ clayey very fine. From 1920s to 1960s, Mangyeong, Gwanghwal and Chonbuk series had coarse silty textured soil. After the 1970s, Mangyeong, Gwanghwal, Munpo, Yeompo, Poseung, Gapo and Hasa series have more sandy soil ~ moderately coarse loamy textured soil. Regarding the chemical properties, the concentrations of EC, Exch. $K^+$, $Mg^{2+}$, $Na^+$ and pH are high regardless of the time of reclamation. On the other hand, organic matter (OM) of top soil were 3.3~16.1 g $kg^{-1}$. The organic matter contents were very low though the soil had been farmed for a long time. Furthermore, the deep soil had almost no organic matter with 5.6~1.1 g $kg^{-1}$. The reason is believed that there had not been any movement of OM and clay because pressure or induced pans had been formed by large agricultural machineries and poor vertical drain. Regarding the forming of illuvial horizon (B layer) which tells the development extent of soil, only in the Hwapo reclaimed area where rice had been cultivated for past 90 years, Fe and Mn from top soil are deposited at underground 20~30 cm with 7~8 cm thickness by the movement of clay. It is believed that it had been possible because the earthiness is silty clay loam soil with relatively high content of clay. The soils are soil with concern of damage from sea water, soil on flimsy ground and sandy soil. Therefore, soil improvement for stable crop production can be expected; if the water table would be lowered by subsurface drainage, the water permeability would be enhanced by gypsum and organic matter, and the sandy soil would be replaced by red soil with high content of clay.

A Study on Therapeutic Compliance of Hypertensive Patients in a Rural Health Subcenter (일개 농촌지역 보건지소 고혈압 환자의 치료지속성)

  • Song, Min-Keun
    • Journal of agricultural medicine and community health
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    • v.27 no.1
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    • pp.155-164
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    • 2002
  • Hypertension is the most frequent disease of chronic circulatory diseases and major intermediate cause or risk of the cerebrovascular disease which is a leading cause of death in Korea. Therefore, management of hypertension is an important issue in Korean healthcare. Especially, therapeutic compliance of hypertensives is very important because the hypertensive patients should receive anti-hypertensive treatment as long as the condition exists. However, many patients drop out of treatment, which is a major problem that needs to be solved through a hypertension control program. This study was carried out to provide basic data and counter measule for the hypertension control program in the community which aimed to keep the patients receiving treatment continuously. In order to investigate compliance of hypertensive patients during three months follow-up and the rate of control of hypertension, the data were collected during February, 2001, by reviewing medical records of 295 hypertensive patients who had been registered to Gunnam-myeon health subcenter before November, 2000. The author also study the dropout reasons by interviewing 58 patients among 68 dropout patients. The results were as follows: 1. Among the 295 subjects, 108(36.6%) were male and 187(63.4%) were female. Statistically, female hypertensives had a higher mean age than male(64.6 vs 66.3, p<0.05). 2. The 54.9% of the patients took anti-hypertensive medicine continuously for the past three months. And 19.3% had drug intermittently, and 25.8% dropped out of treatment. 3. Among several variables, such as sex, age, health insurance, the time taken from a patient's village to the health subcenter, only the last one was found to be significantly related to therapeutic compliance in the contingency table analysis. 4. The dropout reasons by multiple response were as follows, 'no symptom or no problem' (23.9%), 'change to other hospitals'(19.4%), 'geographical barrier'(17.9%), 'change to a neighborhood drugstore' (14.9%), 'immobility'(7.5%), 'economic barrier'(6.0%), 'unsatisfactory services of the health subcenter'(4.4%). 5. The mean blood pressure of 295 subjects was $144.9{\pm}12.9/86.88{\pm}8.6mmHg$. 6. The 32.5% of the subjects were controlled below 140/90mmHg. Conclusions: In order to improve the low rates of treatment and control of hypertension in rural hypertensives, a more active and systematic hypertension control program, including out-reaching follow-up management, is required in rural area. Especially, for health education of hypertensive patients, emphasis should placed on correcting wrong attitude toward hypertension.

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The Family History of Chronic Diseases, Food Group Intakes, and Physical Activity Practices among School Children in Seoul, Korea (서울지역 일부 초등학생의 생활 습관병 가족력, 식품군 섭취 형태 및 활동량 평가)

  • Lee, Young-Nam;Ha, Ae-Wha
    • Journal of the East Asian Society of Dietary Life
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    • v.17 no.5
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    • pp.644-652
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    • 2007
  • In this study, we examined family history of chronic diseases, food group intake and physical activity in $5^{th}\;and\; 6^{th}$ grade elementary school children. Food group intake was compared with the KDRI food guides for children. The measurements of daily physical activity, television viewing, computer use, and daily servings of five food groups, including grains, meats, dairy products, fruits, and vegetables, were based on child and parent self-reports. As indices of obesity, the obesity index(%) and BMI(Body Mass Index) were used. The results were as follows. In boys, 83.2% were normal weight with 7.4% slightly obese, 7.4% moderately obese, and 2.0 were highly obese while the percentages of normal and slightly obese in girls were 89.9% and 6.2% respectively (p<0.05). The boys had more hours of daily physical activity(p<0.05) and more hours of computer usage(Internet searching or games)(p<0.05) than the girls. Slightly over 50% of the subjects met the daily recommended servings of grains, dairy products, fruits, and vegetables according to the KDRI food guides. However, only 26% of boys and 27% of girls met the recommended daily servings of protein foods such as meats, beans, and eggs. Thirty two percent(32%) of girls consumed high fat snacks everyday while 32% consumed high sugar snacks every day. The girls consumed more vegetables(p<0.05) and more high sugar snacks(p<0.05) than the boys. The children with family histories of obesity showed greater obesity rates(p<0.05) and sedentary lifestyles(p< 0.05) than those children without a family history of obesity. Children with family histories of high blood pressure consumed more sewings of vegetables and high fat snacks than the controls(p<0.05). The children with family histories of obesity consumed more high sugar or high fat snacks than the controls(p<0.05).

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Evaluation of Perinatal and Management Factors Associated with Improved Survival in Extremely Low Birth Weight Infants (출생 체중 1,000 g 미만의 초극소 미숙아의 생존율 향상과 연관된 산과 및 치료인자)

  • Park, Sung Eun;Jeon, Ga Won;Choi, Chang Won;Hwang, Jong Hee;Koo, Soo Hyun;Kim, Yu Jin;Lee, Chang Hoon;Chang, Yun Sil;Park, Won Soon
    • Clinical and Experimental Pediatrics
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    • v.48 no.12
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    • pp.1324-1329
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    • 2005
  • Purpose : The aim of this study was to evaluate recent improvements in the survival rate of extremely low birth weight (ELBW) infants and to identify perinatal and management factors that are associated with improved survival. Methods : Two groups of ELBW infants who were admitted to our neonatal intensive care unit (NICU) during two distinct eras : November 1994-December 1999 (Period 1 : n=100) and January 2000-April 2004 (Period 2 : n=166) were retrospectively reviewed. Results : Despite the younger gestational age and smaller birth weight of the ELBW infants in period 2, not only did their survival rate increased to 75 percent from 60 percent in period 1, but their incidence of morbidities such as bronchopulmonary dysplasia, confimed sepsis and intraventricular hemorrhage (${\geq}$Grade III) also declined. Factors significantly associated with improved survival included the use of antenatal steroids, a longer duration of nasal continuous positive airway pressure and the absence of intraventricular hemorrhage (${\geq}$Grade III). Conclusion : We believe that optimized clinical practice, that emphasized less invasive care, contributed to the recent improvements in the survival rate of ELBW infants.

Experimental and Numerical Study on the Effect of the Rain Infiltration with the Increase of Surface Temperature (지표면 온도상승이 빗물의 토양침투에 미치는 영향에 대한 실험 및 수치 해석적 연구)

  • Shin, Nara;Shin, Mi Soo;Jang, Dong Soon
    • Journal of Korean Society of Environmental Engineers
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    • v.35 no.6
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    • pp.422-429
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    • 2013
  • It is generally known that the increase of the Earth surface temperature due to the global warming together with the land desertification by rapid urban development has caused severe climate and weather change. In desert or desertification land, it is observed that there are always severe flooding phenomena, even if desert sand has the high porosity, which could be believed as the favorable condition of rain water infiltration into ground water. The high runoff feature causes possibly another heavy rain by quick evaporation with the depletion of underground water due to the lack of infiltration. The basic physics of desert flooding is reasonably assumed due to the thermal buoyancy of the higher temperature of the soil temperature than that of the rain drop. Considering the importance of this topic associated with water resource management and climate disaster prevention, no systematic investigation has, however, been reported in literature. In this study, therefore, a laboratory scale experiment together with the effort of numerical calculation have been performed to evaluate quantitatively the basic hypothesis of run-off mechanism caused by the increase of soil temperature. To this end, first, of all, a series of experiment has been made repeatedly with the change of soil temperature with well-sorted coarse sand having porosity of 35% and particle diameter, 2.0 mm. In specific, in case 1, the ground surface temperature was kept at $15^{\circ}C$, while in case 2 that was high enough at $70^{\circ}C$. The temperature of $70^{\circ}C$ was tested as this try since the informal measured surface temperature of black sand in California's Coachella Valley up to at 191 deg. $^{\circ}F$ ($88^{\circ}C$). Based on the experimental study, it is observed that the amount of runoff at $70^{\circ}C$ was higher more than 5% compared to that at $15^{\circ}C$. Further, the relative amount of infiltration by the decrease of the surface temperature from 70 to $15^{\circ}C$ is about more than 30%. The result of numerical calculation performed was well agreed with the experimental data, that is, the increase of runoff in calculation as 4.6%. Doing this successfully, a basic but important research could be made in the near future for the more complex and advanced topic for this topic.

A Study on the Effective Controlling System of Radio-activity Ventilation (RI사용 의료기관의 효율적인 배기관리 방안)

  • Lee, Kyung-Jae;Lee, Jin-Hyung;Kim, Kyung-Hoon;Kwack, Dong-Woo;Jo, Hyun-Duck;Ko, Kil-Man;Park, Young-Jae;Lee, In-Won
    • The Korean Journal of Nuclear Medicine Technology
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    • v.12 no.1
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    • pp.91-98
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    • 2008
  • Purpose: Radio-isotopes (RI) use has been steadily developing due to industrial and technical development in the modern medical society. Particularly, popularization of domestic cyclotrons dramatically enable hospitals to produce and use diagnostic radio-isotopes. Generally, only specific facilities such as hospitals, research institutes, nuclear power plants and universities can use radio-isotopes, they are also responsible for ventilation system. The strength of radioactivity in the air is strongly regulated and controlled by korea atomic energy law in Korea Institue of Nuclear Safety (KINS), so that air radioactivity exposure can lead to environmental pollution surrounding places. In this study, we'd like to find out the investigation and the present condition of the controlled ventilation system in domestic hospitals by an emission standard from KINS, and try to reach an agreement about how to use the ventilation system. Result: Definition of filters, features and structures of pre-filters, hepa-filters, charcol filters, filter exchange procedures and precautions are explained. RI deflation concentration and filter exchange cycle have been presented as a standard prescribed in the rules of KINS. The Radiation Control Management System (RCMS) introduced by Seoul National University Bundang Hospital linking to digital pressure gauge with computer controller in another medical facilities were described in details. Conclusions: The system of medical facilities using RI has been remarkably developing in 21 century. Especially, radiation safety control system has also been grown rapidly into the subdivision, specialization, advanced technology along with international technical improvement. However, As far as current RI ventilation system is concerned, it has nothing better than doing in the past. Preferentially, to reinforce this, more sophisticated system with strict periodic filter exchange and exhaust air control guidance should be introduced by applying brilliant domestic information technology for RCMS and digital gauge method. From personal point of view as a radiation safety manager, I have provide with present problems and improvements. Futhermore, more improved guidance should be conducted.

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