• Korean Journal of Clinical Pharmacy
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• v.20 no.3
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• pp.235-241
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• 2010

Bambuterol hydrochloride, dimethylcarbamic acid 5-[2-(1,1-dimethylethyl)amino-1-hydroxyethyl]-1,3-phenylene ester hydrochloride, is the prodrug of active ${\beta}_2$-adrenergic metabolite terbutaline. The purpose of the present study was to evaluate the bioequivalence of two bambuterol hydrochloride tablets, $Bambec^{(R)}$ tablet 10 mg (Yuhan Co., Ltd.) and Bambucol tablet 10 mg (Sam Chun Dang Pharm. Co., Ltd.), according to the guidelines of Korea Food and Drug Administration (KFDA). In vitro release of bambuterol from two bambuterol hydrochloride formulations was tested using KP VIII Apparatus II method with various dissolution media. Twenty eight healthy male Korean volunteers, $23.86{\pm}1.65$ years in age and $68.98{\pm}9.58$ kg in body weight, were divided into two groups and a randomized $2{\times}2$ cross-over study was employed. After two tablets containing 10 mg as bambuterol hydrochloride were orally administered, blood samples were taken at predetermined time intervals, and the concentrations of bambuterol in serum were determined using column switching HPLC with UV detector. The dissolution profiles of two formulations were similar in all tested dissolution media. The pharmacokinetic parameters such as $AUC_t$, $C_{max}$ and $T_{max}$ were calculated, and ANOVA test with K-BE Test 2002 was utilized for the statistical analysis of the parameters using logarithmically transformed $AUC_t$, $C_{max}$ and untransformed $T_{max}$. The results showed that the differences between two formulations based on the reference drug, $Bambec^{(R)}$, were -8.10%, -3.82% and 12.65% for $AUC_t$, $C_{max}$ and $T_{max}$, respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log 0.8 to log 1.25 (i.e., log 0.8093~log 1.0302 and log 0.8564~log 1.1280 for $AUC_t$ and $C_{max}$, respectively). Thus, the criteria of the KFDA bioequivalence guideline were satisfied, indicating Bambucol tablet 10 mg was bioequivalent to $Bambec^{(R)}$ tablet 10 mg.

• Journal of Korean Public Health Nursing
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• v.3 no.1
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• pp.101-119
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• 1989

In the present, since a five-year plan for economic development which was started in the early 60's has been successfully promoted for a quarter century, with consolidation in a department of social welfare in our country the participation. in economic society for women is more required than any other times. As a professional occupation for women is incereaing through a high-standard specialization, I think the upbringing for productive woman expert who has a strong motive of accomplishment as a developed person as well as a technical and skilful capacity which can be contributed to the growth of organization is very important. So in this study, I am evaluating the technical disposition of character of professional nurses working with hospital and also trying to supply the basic data being served to th extension of a skillful ability as a nurse, understanding the important factor related to it. The research method applied here is that we used 527 of formed questionnaires which were distributed to 7 University and General Hospitals, somewhat large in a scale, located in Seoul as an analytical material. It was performed between October 11, 1988 and October 18, 1988. An implement which was invented by Cho Moo-Sung is used after being amended and supplemented, which can measure the disposition of professional character. The formation of questionnaires of the disposition of character is 26 totally, 10 for Open-disposition, 11 for Active-disposition, 5 for wise-disposition, and it was measured. 'Ye', or 'No' through an one-half-standard and the environment of hospital organization is composed 12 questions from one point of 'Very Good' to 5 points of 'Very Bad.' Collected materials were analysed through an electronic calculation into the average value, the standard deflection, percentage, person correlative number, $X^2-test, m$ stepwise multiple regression. Summarizing the result from this research is as follows; 1. The average age of the subjective person of this investigation is 28.6 and the average career as a nurse is 6.0 years. 2. The Open-disposition that technical nurses showed is mostly half and half. 3. The Active-disposition of professional nurses was discovered affirmative largely and what they said in their questionnaires describes that they are very active answering $88.2\%$ for the disposition of self-control, $87.3\%$ for the people who think the training more seriously. 4. It was found out that the wise·disposition of technical nurse showed $90.7\%$ of 'Yes' about a new alternative of inquisitive question and we can see a progressive and profound aspect here. 5. As technical character of nurses, mutual relations between Active-disposition, Active-disposition, and wise­disposition were very profitably revealed as 0.42 in justice relations and also suggested that relations between Open-disposition, Active-disposition, and wise-disposition are 0.27 and 0.20 respectively. 6. What nurses recognize about the environment of hospital organization is reasonably acceptable while they feel very bad about rewards and punishments showing average 3.1 comparing to average 2.2 about time­control each other. Considering the prosperity of Active-disposition upon the result what I mentioned above, th possibility which is contributed to the productive improvement of hospital organization is very great and I think it can be more developed as a professional woman who has a strong motive of accomplishment, in advance.

• Journal of Korean Society of Forest Science
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• v.102 no.3
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• pp.382-389
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• 2013

The present study grasped the operation characteristics and operation management of forest museums in Korea and analyzed satisfaction with the foregoing. In the results of a survey of forest museums' operation characteristics, with regard to groups to which exhibits were helpful, over half of respondents answered that the exhibits were helpful to students and many respondents had an opinion that all age groups should be equally considered as targets of exhibition. Among matters that were considered with regards to forest museums, accessibility showed the highest rate of answers followed by museum programs. The curator was needed for the majority of respondents were exhibits prior to the survey had the highest expectations for the medium. With regard to the operation management of forest museums, the expected value of periodic and extraordinary exhibitions was shown to be high and high and satisfaction was shown by the professionalism of staff. As for matters of forest museums that must be improved, attention should be paid to the development of programs in which users can participate, diverse exhibition media should be developed, and exhibition should be planned to fit the composition of exhibits. As for operation management, since exhibits were repeated every year, environments should be changed by exhibiting new exhibits or otherwise and active methods of improvement should be devised such as the utilization of broadcasting media for public relations.

• Journal of Technologic Dentistry
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• v.30 no.1
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• pp.83-96
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• 2008

This study aims to analyze the major factors in their working conditions affecting the enlargement of leisure activities of dental technicians. We also present a need for dental technicians to assign more time many different kinds of leisure activities for their quality life. To this end, we examined the status and the characteristics of dental technicians' leisure activities among the randomly selected subjects who are working in the area of Seoul, Gyonggido, and Gangwon-do through the analysis of the 311 sheets of self-administered questionnaires. The conclusions from this analysis are as follows; 1. On weekdays, non participants in leisure activities were found to be 64.0%, and in the case of weekends, the participants were reached to 70.7%. Those who enjoy any leisure activities in either of weekdays and weekends were 34.1%, 27.3% of the dental technicians did not have any leisure activities. Therefore, statistical significance was shown in the participations of leisure activities between weekdays and weekends. 2. Of the types of leisure activities in both weekdays and weekends, sports activities were ranked at the top 33.4%, 29.6% respectively, which is followed by going to the cinema/theatre/exhibitions, etc 21.9%, 26.0%, games/entertainment 14.5%, 14.8%, hobbies/cultural activities 14.1%, 12.5%, sightseeing/picnic 6.4%, 7.4%. 3. Of the differences in the characteristics of leisure activities, the types of leisure activities between weekdays and weekends showed difference in gender, company and information regarding leisure activities in age, company and the place of leisure activities, and leisure information in the marital status, career and monthly income in company, company and leisure information in the job position, which is statistically significant (p<.001). However, no statistical significance was found among the other general items of the characteristics of leisure activities. Considering only works on weekdays policy is currently permeating into almost every business sector, dental business owners or managers are advised to consider more effective time management or human resources management, such as keeping reasonable manufacturing time through cooperations with the dentists, regularity of working hours, incentive system, introduction of credible over time payment. Which will provide their staff with more times and opportunities to enjoy their leisure activities. Additionally, the concrete and feasible ways of motivating and activating the leisure activities of dental technicians are in need of further researches and studies.

• Journal of Korean Academy of Nursing
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• v.30 no.1
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• pp.194-201
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• 2000

The propose of the study is to try to support the practice of caring suitable for our cultural emotion by cognating the meaning of caring related to health which is melted in korean culture. Concrete purposes were as followings; to first, confirm the caring of civilian in Kangwon-do, to secondly search the caring in the traditional culture idea, and to thirdly present the conceptual frame about the caring. The methodology of this research is the ethnography to use the depth interview and the participative observation. The geographical area of this research was in Wichon-ri, Songsan- myon, Study participants were, 6men and 18women, totally 24 persons. Their average age was 72.6 years old. The period of data collection was from January, 1998 to April, 1999, which original data became saturation. Data collection was done after accept allowance of the participants, their stories were recorded in cassettee, by the way of the Spradley analysis was applied and adjusted. The results which was analyized as domain, category and property were as following; First, the category was the life serving other persons, which is the for mind, the benefiting one, the comprehensive one, the respective one, on soon. Second, the category was the controling life, and its property was the moderate mind, that is, vegetables were tried to be fed moderately, pleasantly and comfortable. Thirdly, the category was the eagerness life, and the properties were diligent mind, and mind which accomplished the complete resposibility. Fourth, the category was a happy life, and the properties were positive mind, satisfying one, thankful one, one of their ancestors benefit, and supplicatory one. Fifth, the category was the accepting life, and the properties were the submissive mind, resign one. Sixth, the category was the joint life all together and the properties were the harmonized mind, and the mutual helping one. Seventh, the category was the ruling life, and the properties were the pure mind, the ones which controls the body, the mind, the nature; which could surely confirmed the source of the life that lived with the nature, the native idea of our people. Eighth, the category was the retaining life, and the properties were the inherits the native custom, and the one that keep public morals. According to the result of examining the caring in ethnography, the general caring was performed the conceptual frame about the caring which is related to health was found in the principle of consideration, harmony, compliance, and transcendence.

• Journal of Korean Academy of Nursing
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• v.2 no.1
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• pp.87-96
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• 1971

This Study was undertaken to evaluate the present health status and fatigue of the workers in T. Industrial Company in Pusan in Jan. 1971. The results were based on a question are from 354 working girls. The results of this study are as follows: 1. The largest portion of the workers, 20.2% of the questioned employees, were observed to lie at age 20. 2. Regarding their formal education, 76.0% of them had completed middle school. while only 7. 1% had graduated from high school, . 3. 63.0% receive 7-8 hrs. of sleep a day while 18.4% receive S-6 hrs. of sleep a day. 4. 36.4% spend leisure time reading: while 15.5% spend it resting and thinking. 5. 53.8% of them live in the company′s dormitory and 31.6% live at home. 6. Time spent in travel to work: 32.8% spent 40-49 min., 23.6% spent 10-29 min. 7. The shift times were reported as: 44.1% wonting from 8 A.M. to 4 P.M. and 33.9% working from 6. A.M. to 2. P.M. which is what they are doing now. 8. Regarding symptoms of fatigue: 1) Physical symptoms were: 48.3% complained of "feeling bean in the legs, ", and 39.3% complained of "general exhaustion. " 2) Psychological symptoms were: 37.6% said that "it is boring to talk"and 26.3% said" they had a desire to be alone". 3) Nitrogenic symptoms were 49.7% complained of "asthenopia"and 37.0% complained of"vertigo and "staggering legs". 9. When asked about the most fatiguing time during work, the following information was reported: 25.2% felt the first hour in the morning was most fatiguing while 22.9% felt the sixth hour in the evening, and 22.8% eelt the fifth hour at night was. 10. 38.4% complained of sleepiness at 3 A.M. and 35.0% at 4 A.M. during night work. 11. 38.1% found Sunday the most fatiguing work day and 20.% found Monday. 12. The results of the effects of their work on certain diseases: 51.1% showed those with anemia as most effected by work. 13. In their Response to the question, "do you eat breakfast\ulcorner"57.0%, the largest portion, answered, " none at all ": 36.3%, enough. 14. Regarding the accident rate relating to the length of time employed at the company 28.5% was the highest accident rate from 5year to 6 year. As a result of this study, it could be concluded that the employer should consider the following points: 1. employ according to the worker′s vocational aptitude. 2. adjust the shifts. 3. offer rest time and off days, and establish recreational facilities. In the end we can contribute to the promotion of the workers of the workers and to the prevention of accidents due to industrial fatigue.

• Journal of Oral Medicine and Pain
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• v.20 no.1
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• pp.39-52
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• 1995

Burning mouth syndrome is characterized by a burning sensation in oral cavity without clinical signs. There has b een no established theories about the diagnosis and treatment. The purpose of this article is to examine the clinical feature of BMS patients of Korean and to present a treatment protocol that can be helpful in clinical applications. The subjects chosen for the study were 52 patients who had visited Department of Oral Diagnosis at Yonsei University Dental Hospital and were diagnosed as BMS. We did questionnaires and precise oral exam, laboratory exam, grouping of our patients, individual treatment for the groups and classification of responses to the treatment. The following results were obtained: 1. Chief complaints were throbbing (71.2%), pricking, stinging, tingling (30.8%), burning(25a%). The tongue is the most frequently affected site (82.7%), followed by full mouth, gingiva, palate, buccal mucosa, lips, throat, labial mucosa and floor of mouth. 2. The average age of onset was 48.1 year and the male to female ratio was 1 to 3. The average duration of symptom was 11.69 months for male and 23.07 months for female. 3. 32.7% of patients had appealed continuous pain, which was the most cases. Aggravating factors were peppery food, salty food, hot food, fatigue, tension conversation, sour food, cold food and toothpaste. Reducing factors were cold food, diet, going to sleep and smoking. 4. Associated symptoms were dry mouth, other life problem, altered taste perception, bad taste, throat pain, tingle and difficulty in swallowing. 5. Most of patients had appealed that there was not associated event on onset of symptom, and the order of prevalence is as fallow; dental treatment, stress, denture wearing, an attack of a systemic disease. 92.3% of patient appealed that there was no psychological withering and 7.7% of patients appealed positively. 6. There were eight males and four females that had jobs. 7. There was no family history in 100% of patients in questions about presence of family history. 8. 96.2% of patients appealed that there was no oral habits. 13.5% of patients had dryness of oral mucosa in oral exam. A significant relation to dental prosthesis was not observable, but incidence of diseases due to stress appeared high in BMS which had the clinical characteristics as above. A group having low serum iron was 63.5% and in this group period of potential iron deficiency appeared high in incidence just before move to anemia. A group represented positive response was 38.5% in fungus study for Candida albicans. Since we can expect high treatment response by prescription of iron-contained drug and antifungal drug in these patients, diagnosing patients' condition of BMS can be achieved in more various aspects through study for serum iron and Candida albicans. Furthermore, it is expected that treatment protocol can be made.

• Research in Community and Public Health Nursing
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• v.4 no.2
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• pp.139-145
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• 1993

The purpose of this study was to identify the degree and the relationship of the Knowledge, Attitude and Practice of industrial health care services of workers. This information will provide useful data for an effective industrial health care service. The was collected from 600 data employees in Kwang-ju city & Chonnam province. The data was gathered by questionnaire from Dec 20, 1992 to Jan 20, 1993. The questionnaire was developed by the Academic Affairs of Community Health Nursing Academy. Data was analyzed by using the statistical computer package, SPSS to manipulate the data along with percentages, means, standard deviations, modes, t-test and ANOVA. The results in this study were summarized as follows: 1. General characteristics of workers: Distributions of workers was laborer(76.2%). in the 25-34 age group(50.2%), married(63.3%), males comprised(77.5%), the educational level with the highest percentage was high school graduates (71.1%), with a monthly income of 300-700 thousand won(43.8%), and has been working in the present career over seven years (31.5%). 2. The Knowledge, Attitude and Practice levels of employees about industrial health care services The levels were measured according to a five point scale. The total mean score of knowledge was 2.92 points out of 4. The following are the scores of Knowledge of special medical examination and location of industrial clinic(3.48), periodic medical examination (3.18), occupational disease(3.08), personal protective equipment (2.92), and health education(1.37). The total mean score of Attitude was 2.77 point out of 4. The following are the scores of Attitude in order of working environment (3.35), necessity of periodic medical examination and health education(3.15), the worker's perception influence on the working environment to health was high(3.11). But, the level of satisfaction in the content of periodic medical examination was low(2.19). The total mean score of Practice was 2.70 points out of 4. The scores of Practice in order were, practice of periodic medical examination(3.70), utilization of industrial clinic(2.92), and to participate in health education(1.47). 3. The relationship of general characteristics to Knowledge, Attitude, and Practice of workers: Knowledge had a significant difference by sex (P<.01), marital status(P<.01), education level (P<.05) and monthly income(P<.01). Attitude was significantly different with sex(P<.05) and Practice was significantly related to monthly income (P<.01).

• Journal of Korean Public Health Nursing
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• v.17 no.2
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• pp.317-332
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• 2003

This study attempts to investigate the relations between the types of communication, the job satisfaction. and the nursing performance of the staff nurses. The subjects of this study were the 114 nurses working in general wards, intensive care units, and the emergency rooms of the general hospital in Kyongbuk province. They were asked to answer the questionnaires as regards the types of communication and job satisfaction, and their performance of nursing, and these were evaluated by the head nurses, and their direct seniors. The data were collected for 10 days from the September 17 to 26, 2002. According to the purpose of the study, descriptive analysis, ANOVA. Pearson correlation coefficient, and stepwise multiple regression were applied for the data analysis using SPSS 10.0. The results are as follows : 1. The types of communication of staff nurses showed that the upward communication was $3.12\pm0.56$. the downward communication was $3.56\pm0.42$. the horizontal communication was $2.98\pm0.44$. and the informal communication was $2.59\pm0.49$. It showed that the most frequent communication was the downward communication. 2. In terms of the job satisfaction, there was significant difference according to the length of the period working for one ward (F=5.95, p=0.003), 3. The performance of nursing was significantly different according to the age (F=23.52, p=0.000), the working duration as a nurses (F=21.9, p=0.000), the types of nursing unit (F=5.33, p=0.002), and the working duration in present nursing unit (F=15.87, p=0.000). 4. In terms of communication type, the job satisfaction was associated with quality of the upward communication (F=6.23, p=0.003), the downward communication (F=5.78, p=0.004), and the horizontal communication (F=11.73, p=0.000) There were no association between the types of communication and the performance of nursing. 5. There was a positive correlation between the communication and the job satisfaction. And the downward communication (r=0.398) showed the greatest correlation with the job satisfaction. There was no statistically significant correlation between the communication and the performance of nursing. And the upward communication (r=-0.058) showed a negative, though not significant correlation with performance of nursing. 5. There was a positive correlation between the communication and the job satisfaction. And the downward communication (r=0.398) showed the greatest correlation with the job satisfaction. There was no statistically significant correlation between the communication and the performance of nursing. And the upward communication (r=-0.058) showed a negative. though not significant correlation with performance of nursing. 6. The stepwise multiple regression result showed that the downward communication accounts for $15.8\%$ (p=0,000) of the job satisfaction.

• Journal of the Korea Convergence Society
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• v.9 no.6
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• pp.299-310
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• 2018

A Convergence study was conducted to investigate the factors influencing the health-related quality of life in patients with chronic neck pain and to present a strategy for effective program development. The participants of this study were 92 patients with chronic neck pain in a region and collected data by self-reported questionnaire. Data were analyzed using PASW 18.0 program, that descriptive statistics, t-test, ANOVA, correlation analysis and stepwise multiple regression analysis were performed. According to the results of stepwise multiple regression, the identified influencing factors were disability(${\beta}=-.403$, p<.001), depression(${\beta}=-.313$, p<.001), age(${\beta}=-.194$, p=.008), muscle disorder(${\beta}=-.176$, p=.009), education(${\beta}=-.151$, p=.043) with health-related quality of life in patients with chronic neck pain. The explanatory power($R^2$) by 5 variables was 67.1%(F=38.118, p<.001). It was found that it is important to consider the individual characteristics, physical function improvement and psychological support for improving the health-related quality of life in patients with chronic neck pain. Therefore, it is necessary to develop a health promotion program based on the factors influencing on the health-related quality of life and analyze its application effect.