• 생약학회지
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• 제21권2호
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• pp.126-129
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• 1990

Platelet anti-aggregating activities were evaluated with three combined crude drug preparations which have been used for 'eahyul'-one of the pathological concept in oriental medicine presumably concerning blood stasis or stagnant syndrome. The water extract of each combined preparation and each component plant was tested for their effects against ADP, arachidonic acid (AA) or collagen induced rat platelet aggregations. Mild inhibitory activities were observed with all the three tested preparations, Kaechibokryung-Hwan, Dangkqijakyak-San and Ohnkyung-Tang, and the component plants which are included in at least two of the above preparations.

• 한방안이비인후피부과학회지
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• 제26권3호
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• pp.20-35
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• 2013

Objectives : The purpose of this study is to provide grounds for the development of preparation of Korean medicine through investigating the usage of smoking preparation, fumigant and buccal preparations in "Dongeuibogam". Methods : We have researched the usage of related preparations as following procedure : 1. Choosing a related words such as combustion(燒, 燎, 燃) smoking(烟), fumigation(熏, 熏烟, 熏洗), inhalation(聞, 嗅, 齅), holding in mouth(含, 噙). 2. Searching sentences : We have searched sentences containing the related words in "Dongeuibogam", analyzed the selected sentences and made tables of the usage including indication, formula, material. Conclusions : 1. Smoking preparations and Fumigant can be classified into two different groups : 1) internal usage for the treatment of internal diseases such as dizziness, congestion, stroke, cough. 2) external usage for the treatment of wounds, sores, genital diseases, anal disease and for the prevention of diseases. 2. Buccal preparation is mainly used for the treatment of mouth, tongue, throat and lung diseases. 3. These preparations have been used not only for external diseases but internal diseases. 4. Each preparation has chief herbs for its peculiar properties of treatment.

• 한국산학기술학회논문지
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• 제16권10호
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• pp.6618-6626
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• 2015

본 연구는 중고령 여성의 경제적 노후준비에 영향을 미치는 요인을 파악하기 위한 목적으로 이루어졌다. 이를 위하여 국민연금연구원의 국민노후보장패널 4차 데이터 활용하여 분석을 실시하였다. 먼저 경제적 노후준비에 따른 중고령 여성의 노후생활에 대한 특성을 살펴보았으며, 경제적 노후준비에 영향을 미치는 요인을 분석하였다. 연구결과 중고령 여성의 경제적 노후준비에 영향을 미치는 요인으로는 교육수준, 건강상태, 청소년기 자녀 수, 청년기 자녀 수, 공적연금 가입, 금융자산, 부채가 나타났다. 이러한 연구결과를 바탕으로 중고령 여성의 경제적 노후준비에 대한 논의 및 제언이 이루어졌다.

• 대한한의학방제학회지
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• 제16권1호
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• pp.95-107
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• 2008

Objectives : Hwangnyeonhaedok-tang(HNHDT) is the one of well-known traditional herbal formula and has been widely used for the treatment of various diseases in Korea. For the quality improvement of commercial traditional herbal formula, we investigated the quality of prepared HNHDT. Methods: We measured the contents of baicalin, berberine and geniposide in the HNHDT Ex preparations on the market by HPLC and compared with the official notice of ingredients. Results: In 3 preparations of HNHDT covered with the national health insurance(NHI), the content of baicalin was various from 32.83mg to 185.05mg, the total berberine was $12.0{\sim}50.75mg$ and geniposide was $12.57{\sim}44.84mg$. Contents of marker ingredients in NHI Preparations were below the standard and showed a large variation. In 7 non NHI Preparations of HNHDT and the standard(STD) HNHDT manufactured in laboratory, the content of baicalin was $37.16{\sim}115.69mg$, the total berberine was $5.62{\sim}28.43mg$ and geniposide was $10.98{\sim}113.47mg$. But, because composition of non-NHI preparations is different from NHI preparations, every maker's contents were up to the notice for baicalin and berberine. There was newly enforced standard regulations of geniposide in non-NHI preparations, so contents of geniposide was up to that standard only in JI and STD. Conclusions: There was a large variation of contents in the HNHDT Ex preparations on the market and the quality differences were existed between NHI and non-NHI preparations of HNHDT. Further studies for evaluation of efficacy differences and standardization of manufacturing processes are necessary.

• 대한한의학회지
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• 제35권3호
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• pp.135-154
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• 2014

Purpose: There is an issue in applying various principles introduced in established Korean medical classics to "Pharmaceuticals Approval, Notification and Review" of "herbal medicinal preparations" and "new drugs from natural products" that are used for western forms of medical treatment. Thus, an analysis of the origin, purpose, and application of established Korean medical classics in the Korean Pharmaceutical Affairs Act is essential. Methods: We collected data regarding the origin, purpose, and application of established Korean medical classics in the Korean Pharmaceutical Affairs Act, and classified them by periodical change and subjects. Results: Established Korean medical classics are applied as follows: 1) as criteria for Korean medicine distributors' sales of mixed herbal drugs (Pharmaceutical Affairs Act; since 1953), 2) as official compendiums for pharmacists' preparation of Korean medicine (Ministry of Health and Welfare's authoritative interpretation; from early 1970s to 1993), 3) as standards for oriental pharmacists' quality measurement of preparations (notification of the Ministry of Health and Welfare; since 1995), 4) as criteria for "Pharmaceuticals Approval, Notification and Review" of herbal medicinal preparations and crude drug preparations (notifications regarding drug approval process by the Ministry of Health and Welfare and the Ministry of Food and Drug Safety; since 1978), and 5) as standards for the quality of materials of health functional food (from 2004 to 2011). Conclusion: The application of Korean medical classics has been closely related with the change of the laws, regulations, and systems that are relevant to Korean medicine, and it seems to be more favorable for pharmacists than oriental pharmacists. Meanwhile, regulations that apply prescriptions that are recorded in Korean medical classics - dosage, indications, and preparation methods - as criteria for the approval of crude drug preparations for western medical treatment should be abolished.

• Archives of Pharmacal Research
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• 제29권11호
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• pp.1055-1060
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• 2006

The objective of this study was to formulate itraconazole semisolid dosage forms and characterize their physicochemical properties. Itraconazole and excipients such as polysorbate 80, fatty acids, fatty alcohols, oils and organic acids were melted at $160^{\circ}C$. The fused solution was then cooled immediately at $-10^{\circ}C$ to make wax-like semisolid preparations. Their physicochemical attributes were first characterized using differential scanning calorimetry, Fourier transform infrared spectroscopy and nuclear magnetic resonance spectrometry. The solubility of itraconazole in semisolid preparations and their dispersability in the simulated gastric fluid were also determined. Our semisolid preparations did not show any distinct endothermic peak of a crystalline form of itraconazole around $160-163^{\circ}C$. This suggested that it was changed into amorphous one, when it was formulated into semisolid preparations. In addition, the distinctive functional peaks and chemical shifts of itraconazole were well retained after processing into semisolid preparations. It could be inferred from the data that itraconazole was stable during incorporation into semisolid preparations by the hot melt technique. In particular, itraconazole semisolid preparations composed of polysorbate 80, fatty acids and organic acids showed good solubility and dissolution when dispersed in an aqueous medium. It was anticipated that the semisolid dosage forms would be industrially applicable to improving the bioavailability of poorly water-soluble drugs.

• 대한한의학회지
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• 제30권4호
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• pp.37-46
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• 2009

Objectives: The purpose of this study was to investigate the external application of paste preparation recorded in the Annals of the Chosun Dynasty (朝鮮王朝實錄) and to clarify the significance of modern use of plaster therapy. Methods: Of many paste preparations, records of All-applying ointment (萬應膏), One-great ointment (太一膏), Pain-relieving plaster (救苦膏), and Pus-promoting powder (促膿膏) were especially examined from the Annals of the Chosun Dynasty. Other medical records regarding how these preparations were passed onto later generations were also studied. Results: According to the records from the Annals of the Chosun Dynasty, paste preparations were mainly used to cure abscess and sore, partly to treat pain diseases. From other medical documents, it could be found that these preparations were continuously used in subsequent eras. Conclusions: From these records, the level and features of Chosun Dynasty medicine could be speculated. It is necessary to find and restore effective paste preparations in Traditional Korean Medicine to use for treating disease today. Therefore, records from the Annals of the Chosun Dynasty are important and meaningful materials.

• Journal of Pharmaceutical Investigation
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• 제17권1호
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• pp.31-37
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• 1987

The studies on concurrent administrations of herb preparations(Daesiho-tang, Daehwangmogdanpi-tang, Dohaegseunggi-tang, Baenongsangeub-tang and Jeoryeong-tang) with indomethacin and tetracycline were carried out to investigate the antiinflammatory, antimicrobial, liver-protective and antiulcer activities. The results showed that the concurrent administrations of herb preparations with indomethacin and tetracycline increased significantly the antiinflammatory activities and antimicrobial activities respectively, and also improved the liver-protective activities and antiulcer activities against indomethacin or tetracycline-induced liver defect and Shay ulcers in rats, respectively.

• 대한치과의사협회지
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• 제11권4호
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• pp.271-276
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• 1973

This study is concerned with the effect on Penetration of varing the length of time among the applications of stains, preparations of medicine and radio-active isotope of siver in 120 carious or non carious human teeth with a vital pulp. The study revealed the following conclusions : 1) The stains and preparations penetrated through the dentinal tube and it's seem to be ceased at zone of secondary dentinal area. 2) The stains and preparations did not penetrated in enamel tissues.

• 고려인삼학회:학술대회논문집
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• 고려인삼학회 1980년도 학술대회지
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• pp.217-222
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• 1980

By means of numerous examples the practical possibility is demonstrated, which HPLC offers at the quality control of Ginseng-preparations. The method is not only suitable for quali-quantitative evaluation of finished products, but also for in-process controls at production of Ginseng specialities. From the examination of various German products which are on the European market, it results, that the contents of Ginsenosides fluctuate strongly. The mechanisms are shown, which could cause destruction of the Ginsenosides at the processing of Ginseng roots. The guiding principles for the production of standardized Ginseng preparations are defined.