Korean Journal of Pharmacognosy (생약학회지)
- Volume 21 Issue 2
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- Pages.126-129
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- 1990
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- 0253-3073(pISSN)
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- 2288-9299(eISSN)
Effects of Some Combined Crude Drug Preparations against Platelet Aggregations
수종 생약제제들의 혈소판 응집억제 작용
- Kim, Jae-Hoon (Natural Products Research institute, Seoul National University) ;
- Yoo, Young-Sun (Natural Products Research institute, Seoul National University) ;
- Mang, Mi-Ho (Natural Products Research institute, Seoul National University) ;
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Yun-Choi, Hye-Sook
(Natural Products Research institute, Seoul National University)
- Published : 1990.06.30
Abstract
Platelet anti-aggregating activities were evaluated with three combined crude drug preparations which have been used for 'eahyul'-one of the pathological concept in oriental medicine presumably concerning blood stasis or stagnant syndrome. The water extract of each combined preparation and each component plant was tested for their effects against ADP, arachidonic acid (AA) or collagen induced rat platelet aggregations. Mild inhibitory activities were observed with all the three tested preparations, Kaechibokryung-Hwan, Dangkqijakyak-San and Ohnkyung-Tang, and the component plants which are included in at least two of the above preparations.
Keywords
- Platelet anti-aggregating activities;
- ADP;
- arachidonic acid(AA);
- collagen;
- 'eahyul'-boold stasis;
- crude drug preparations(Kaechibokryung-Hwan-Dankqjakyak-San-Ohnkyung-Tang)