• 제목/요약/키워드: predictive value

검색결과 1,112건 처리시간 0.03초

Sperm Penetration Assay의 임상적 타당성에 관한 연구 (Study on the Clinical Validity of Sperm Penetration Assay)

  • 방명걸;오선경;신창재;김정구;문신용;장윤석;이진용
    • Clinical and Experimental Reproductive Medicine
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    • 제20권1호
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    • pp.1-7
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    • 1993
  • The present study was designed to test the validity of the semen analysis(S/A) and the sperm penetration assay(SPA) as a prognostic indicator of male fertility in 123 patients undergoing in vitro fertilization(IVF). We attempted to correlate the traditional semen parameters or the extent of sperm penetration in SPA with the results of human IVF rate or cleavage rate. Poor correlation was found between the results of S/A and human IVF rate(sensitivity, 80.6% ;specificity, 46.7%; positive predictive value, 91.6%;negative predictive value, 25%). Conversely, good correlation was found between the results of SPA and human IVF rate(sensitivity, 100% ; specificity, 80% ;positive predictive value, 97.3% ;negative predictive value, 100%). Our results corroborate the conclusion that SPA can be a valuable tool as a prognostic indicator of male fertilizing ability.

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시각유발전위 검사상 후-시신경교차부위병변을 보인 환자들의 뇌 영상 결과와의 연관성 (Visual Evoked Potentials in Retrochiasmal Lesion; Correlation with Neuroimaging Study)

  • 김성훈;조용진;김호진;이광우
    • Annals of Clinical Neurophysiology
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    • 제2권1호
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    • pp.13-20
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    • 2000
  • Background and Objective : Visual evoked potentials(VEPs) is considered to be a reliable diagnostic procedure for examining patients with anterior visual pathways. Some abnormalities in the recordings on monocular stimulation have been said to indicate retrochiasmal lesion, but less consistent results have been reported. This study is to evaluate the positive predictability of VEP for the detection of retrochiasmal lesion. Methods : We reviewed VEPs that could be interpreted as indicative of a retrochiasmal lesions, based on amplitude or latency asymmetry recorded on the left(O1) and right(O2) occipital regions. Bilateral absent VEPs on both recording(O1 and O2) without evidence of prechiasmal lesion were included. During 5 years, we identified 31 patients who met the above criteria and who had undergone magnetic resonance imaging(MRI) of brain(one patient underwent computerized tomography). Twenty three patients underwent pattern reversal VEPs and others underwent flash goggle VEPs. Results : Brain imagings were abnormal in 29 and were normal in 2. Of the 29 abnormal scans, lesions in posterior visual pathway were detected in 21 scans(predictive value=68%). The predictive value was not significantly different between flash goggle VEP(75%) and pattern reversal VEP(68%). The predictive value was higher in patient with visual field defect(100%) than those without visual field defect(25%). The pathologic nature of lesion also showed close relations to the predictive value. VEPs is usually paradoxically lateralized(78%), but not in all patients. Conclusion : VEPs abnormalities suggesting retrochiasmal lesion were usually corresponded with brain MRI findings. Diagnostic reliability could be increased when considering the visual field defect and nature of lesion. Therefore, the authors suggest that VEPs studies could be useful in evaluating the patients with the retrochismal lesion.

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Clinical predictors of therapeutic laparotomy in anterior abdominal stab injuries: a multicenter study from low-income institutions in Ethiopia

  • Segni Kejela;Abel Hedato;Yeabsera Mekonnen Duguma;Meklit Solomon Gebremariam
    • Journal of Trauma and Injury
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    • 제37권2호
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    • pp.140-146
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    • 2024
  • Purpose: Despite the high incidence of abdominal stab injuries, the rate of nontherapeutic laparotomies and the predictors of therapeutic laparotomies have rarely been studied in low-income settings. Methods: This multicenter retrospective study involved three of the largest academic medical centers in central Ethiopia. All patients who sustained an anterior abdominal stab injury and underwent exploratory laparotomy, regardless of the intraoperative findings, were included over the 3-year course of the study. Results: Of the 117 patients who underwent exploratory laparotomy, 35 patients (29.9%) underwent nontherapeutic laparotomies. Three factors predicted therapeutic laparotomy: hollow viscus evisceration (adjusted odds ratio [AOR], 5.77; 95% confidence interval [CI], 1.16-28.64; P=0.032), localized and generalized peritonitis (AOR, 4.77; 95% CI, 1.90-11.93; P=0.001), and white blood cell count ≥11,500/mm3 (AOR, 2.77; 95% CI, 1.002-7.650; P=0.049). The overall positive predictive value of the therapeutic predictors was 80.2%, while the negative predictive value of all predictor-negative patients was 58.1%. The predictors would have prevented 51.4% of the nontherapeutic laparotomies. Conclusions: Close to one-third of the patients had a nontherapeutic laparotomy. The clinical predictors of therapeutic laparotomy were shown to have a high positive predictive value despite a lower negative predictive value. Further prospective studies that involve all patients who sustain anterior abdominal stab injuries are needed to potentially improve on the negative predictive value of the predictors suggested by our study.

펄스응답 순환행렬의 특이치 분해를 이용한 강인한 차수감소 모델예측제어기의 설계 (Design of Robust Reduced-Order Model Predictive Control using Singular Value Decomposition of Pulse Response Circulant Matrix)

  • 김상훈;문혜진;이광순
    • 제어로봇시스템학회논문지
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    • 제4권4호
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    • pp.413-419
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    • 1998
  • A novel order-reduction technique for model predictive control(MPC) is proposed based on the singular value decomposition(SVD) of a pulse response circulant matrix(PRCM) of a concerned system. It is first investigated that the PRCM (in the limit) contains a complete information of the frequency response of a system and its SVD decomposes the information into the respective principal directions at each frequency. This enables us to isolate the significant modes of the system and to devise the proposed order-reduction technique. Though the primary purpose of the proposed technique is to diminish the required computation in MPC, the clear frequency decomposition of the SVD of the PRCM also enables us to improve the robustness through selective excitation of frequency modes. Performance of the proposed technique is illustrated through two numerical examples.

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Machine Learning기법을 이용한 Robot 이상 예지 보전 (Predictive Maintenance of the Robot Trouble Using the Machine Learning Method)

  • 최재성
    • 반도체디스플레이기술학회지
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    • 제19권1호
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    • pp.1-5
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    • 2020
  • In this paper, a predictive maintenance of the robot trouble using the machine learning method, so called MT(Mahalanobis Taguchi), was studied. Especially, 'MD(Mahalanobis Distance)' was used to compare the robot arm motion difference between before the maintenance(bearing change) and after the maintenance. 6-axies vibration sensor was used to detect the vibration sensing during the motion of the robot arm. The results of the comparison, MD value of the arm motions of the after the maintenance(bearing change) was much lower and stable compared to MD value of the arm motions of the before the maintenance. MD value well distinguished the fine difference of the arm vibration of the robot. The superior performance of the MT method applied to the prediction of the robot trouble was verified by this experiments.

대퇴 외과 절삭 징후(cut-off sign) - 원판형 외측 반월상 연골 예에서 나타나는 새로운 단순 방사선 소견 - (Femoral Condyle Cut-off Sign - New Indirect Sign of Radiologic Finding in Knee with Discoid Lateral Meniscus -)

  • 하철원;성기선;박재철
    • 대한관절경학회지
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    • 제7권2호
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    • pp.215-219
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    • 2003
  • 목적 : 단순 방사선 사진에서 슬관절 외측 원판형 연골판을 진단하는데 도움이 되는 새로운 방사선 소견인 대퇴외과 절삭 징후(cut-off sign)를 관찰하여 이를 보고하고, 이의 진단적 의의를 특이도, 민감도, 양성 예측도, 음성 예측도와 함께 보고하고자 한다. 대상 및 방법 : 관절경 시술로 확진 된 50예의 완전 원판형 연골군과 50예의 정상 대조군을 대상으로 하였으며, Tunnel view에서 보이는 대퇴 외과와 내과의 내측부의 최장 길이를 측정하여 비율을 비교 분석하였다. 결과 : 원판형 연골군에서 대퇴 내과부 길이와 외과부 길이의 비율의 평균은 0.716 이였으며, 정상 대조군에서는 0.902 이었다. 이를 T-test로 분석했을 때, t-value는 -11.13 (p<0.0001)로 두 군간에 매 우 유의 한 차이를 나타내었으며, 또한 경계값(cut point)을 0.8로 하여 chi-square test로 분석했을 때 통계적으로 두 군간에 유의한 차이가 있었으며, 민감도 $76\%$, 특이도 $100\%$였으며, 양성 예측도 $100\%$, 음성 예측도 $80.6\%$로 나타났다. 절삭 징후는 육안적으로도 뚜렷한 차이를 보여 원판형 외측 반월상 연골을 단순 방사선 사진에서 진단할 수 있는 매우 좋은 간접적인 소견이라고 생각한다. 결론 : 대퇴 외과 절삭 징후는 단순 방사선 검사의 Tunnel view에서 원판형 연골을 진단할 수 있는 좋은 방사선 소견이며, $100\%$의 특이도와 $100\%$의 양성 예측도를 나타내는 우수한 진단소견으로 판단된다.

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Comparison of the Walz Nomogram and Presence of Secondary Circulating Prostate Cells for Predicting Early Biochemical Failure after Radical Prostatectomy for Prostate Cancer in Chilean Men

  • Murray, Nigel P;Reyes, Eduardo;Orellana, Nelson;Fuentealba, Cynthia;Jacob, Omar
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권16호
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    • pp.7123-7127
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    • 2015
  • Purpose: To determine the utility of secondary circulating prostate cells for predicting early biochemical failure after radical prostatectomy for prostate cancer and compare the results with the Walz nomagram. Materials and Methods: A single centre, prospective study of men with prostate cancer treated with radical prostatectomy between 2004 and 2014 was conducted, with registration of clinical-pathological details, total serum PSA pre-surgery, Gleason score, extracapsular extension, positive surgical margins, infiltration of lymph nodes, seminal vesicles and pathological stage. Secondary circulating prostate cells were obtained using differential gel centrifugation and assessed using standard immunocytochemistry with anti-PSA. Biochemical failure was defined as a PSA >0.2ng/ml, predictive values werecalculated using the Walz nomagram and CPC detection. Results: A total of 326 men participated, with a median follow up of 5 years; 64 had biochemical failure within two years. Extracapsular extension, positive surgical margins, pathological stage, Gleason score ${\geq}8$, infiltration of seminal vesicles and lymph nodes were all associated with higher risk of biochemical failure. The discriminative value for the nomogram and circulating prostate cells was high (AUC >0.80), predictive values were higher for circulating prostate cell detection, with a negative predictive value of 99%, sensitivity of 96% and specificity of 75%. Conclusions: The nomagram had good predictive power to identify men with a high risk of biochemical failure within two years. The presence of circulating prostate cells had the same predictive power, with a higher sensitivity and negative predictive value. The presence of secondary circulating prostate cells identifies a group of men with a high risk of early biochemical failure. Those negative for secondary CPCs have a very low risk of early biochemical failure.

데이터마이닝 기법을 이용한 건강보험공단의 수술 통계량 근사치 추정 -허니아 수술을 중심으로- (Estimation of a Nationwide Statistics of Hernia Operation Applying Data Mining Technique to the National Health Insurance Database)

  • 강성홍;서숙경;양영자;이애경;배종면
    • Journal of Preventive Medicine and Public Health
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    • 제39권5호
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    • pp.433-437
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    • 2006
  • Objectives: The aim of this study is to develop a methodology for estimating a nationwide statistic for hernia operations with using the claim database of the Korea Health Insurance Cooperation (KHIC). Methods: According to the insurance claim procedures, the claim database was divided into the electronic data interchange database (EDI_DB) and the sheet database (Paper_DB). Although the EDI_DB has operation and management codes showing the facts and kinds of operations, the Paper_DB doesn't. Using the hernia matched management code in the EDI_DB, the cases of hernia surgery were extracted. For drawing the potential cases from the Paper_DB, which doesn't have the code, the predictive model was developed using the data mining technique called SEMMA. The claim sheets of the cases that showed a predictive probability of an operation over the threshold, as was decided by the ROC curve, were identified in order to get the positive predictive value as an index of usefulness for the predictive model. Results: Of the claim databases in 2004, 14,386 cases had hernia related management codes with using the EDI system. For fitting the models with applying the data mining technique, logistic regression was chosen rather than the neural network method or the decision tree method. From the Paper_DB, 1,019 cases were extracted as potential cases. Direct review of the sheets of the extracted cases showed that the positive predictive value was 95.3%. Conclusions: The results suggested that applying the data mining technique to the claim database in the KHIC for estimating the nationwide surgical statistics would be useful from the aspect of execution and cost-effectiveness.

스마트 가전 사용자는 스마트 세탁기에 무엇을 기대하는가? -스마트 세탁기에 대한 예측적 기대 탐색을 위한 질적 연구- (What do Smart Home Appliance Users Expect from Smart Washing Machines? -A Qualitative Exploration of Predictive Expectations for Smart Washing Machines-)

  • 문희강;김선우
    • 한국의류학회지
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    • 제47권1호
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    • pp.85-109
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    • 2023
  • Laundry has traditionally been regarded as one of the most demanding household chores, but the introduction of smart washing machines is changing this perception. Although smart washing machines have been on the market for several years and consumers' perceptions of washing machines have changed, little is known about consumers' perceptions of smart washing machines. The purpose of this study is to determine what users expect from smart washing machines. We conducted two focus group interviews with sixteen participants who had used smart home appliances to acquire qualitative data. Stimuli created by the interviewees were applied in the focus group interviews to collect more insightful data. We analyzed the data using the three-step method and QSR NVivo. Analysis revealed ten categories of predictive expectations, including seven utilitarian attributes (i.e., smart functionality, smart user interface, reliability, controllability, interactivity, functional value, and economic value) and three hedonic attributes (i.e., fashionable value, psychological value, and social value). The results of this study have implications for the development of smart washing machines that would satisfy consumers by taking user expectations into account.

능동형 소음저감 기법을 위한 도로교통소음 예측 모형 평가 연구 (Evaluation of a Traffic Noise Predictive Model for an Active Noise Cancellation (ANC) System)

  • 안덕순;문성호;안오성;김도완
    • 한국도로학회논문집
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    • 제17권6호
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    • pp.11-18
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    • 2015
  • PURPOSES : The purpose of this thesis is to evaluate the effectiveness of an active noise cancellation (ANC) system in reducing the traffic noise level against frequencies from the predictive model developed by previous research. The predictive model is based on ISO 9613-2 standards using the Noble close proximity (NCPX) method and the pass-by method. This means that the use of these standards is a powerful tool for analyzing the traffic noise level because of the strengths of these methods. Traffic noise analysis was performed based on digital signal processing (DSP) for detecting traffic noise with the pass-by method at the test site. METHODS : There are several analysis methods, which are generally divided into three different types, available to evaluate traffic noise predictive models. The first method uses the classification standard of 12 vehicle types. The second method is based on a standard of four vehicle types. The third method is founded on 5 types of vehicles, which are different from the types used by the second method. This means that the second method not only consolidates 12 vehicle types into only four types, but also that the results of the noise analysis of the total traffic volume are reflected in a comparison analysis of the three types of methods. The constant percent bandwidth (CPB) analysis was used to identify the properties of different frequencies in the frequency analysis. A-weighting was applied to the DSP and to the transformation process from analog to digital signal. The root mean squared error (RMSE) was applied to compare and evaluate the predictive model results of the three analysis methods. RESULTS : The result derived from the third method, based on the classification standard of 5 vehicle types, shows the smallest values of RMSE and max and min error. However, it does not have the reduction properties of a predictive model. To evaluate the predictive model of an ANC system, a reduction analysis of the total sound pressure level (TSPL), dB(A), was conducted. As a result, the analysis based on the third method has the smallest value of RMSE and max error. The effect of traffic noise reduction was the greatest value of the types of analysis in this research. CONCLUSIONS : From the results of the error analysis, the application method for categorizing vehicle types related to the 12-vehicle classification based on previous research is appropriate to the ANC system. However, the performance of a predictive model on an ANC system is up to a value of traffic noise reduction. By the same token, the most appropriate method that influences the maximum reduction effect is found in the third method of traffic analysis. This method has a value of traffic noise reduction of 31.28 dB(A). In conclusion, research for detecting the friction noise between a tire and the road surface for the 12 vehicle types needs to be conducted to authentically demonstrate an ANC system in the Republic of Korea.