• Journal of the Korean institute of surface engineering
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• v.39 no.6
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• pp.276-281
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• 2006

In order to improve the performance of PPFs (Pre-Plated Frames), a PPF that employed a Cu-Sn alloy instead of conventionally used Ni was developed and then its properties were investigated. It was found that the electoplated Cu-Sn alloy layer was a mixture of uniformly distributed fine crystallites, resulting In better wettability and crack resistance than those of Ni PPF. Moreover, as in Cu/Ni/Pd/Au PPF, migration of copper atoms from the base metal to the top of the Cu/Cu-Sn/Pd/Au PPF surface was not found although the Cu-Sn layer itself contained considerable amount of copper. It was expected that, by using the newly developed Cu-Sn PPF, any possible heat generation and signal interrupt caused by an external electro-magnetic field could be reduced because the Cu-Sn layer was paramagnetic, i.e., nonmagnetic.

• Journal of information and communication convergence engineering
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• v.9 no.1
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• pp.32-37
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• 2011

In dispersion management (DM) and optical phase conjugation applied into optical transmission links with multi fiber spans for minimizing the impact of nonlinearity and group velocity (GVD), implementation possibility of DM using only one fiber span for pre- or postcompensation was assessed as a function of duty cycle of RZ pulse and residual dispersion per span (RDPS). It is confirmed that DM with optimal net residual dispersion (NRD) controlled by only one fiber span could be sufficiently applied into optical transmission links, though optimal NRD is more increased than that in transmission links with the general DM scheme of pre- and postcompensation. Thus, it is expected that optical transmission system is simply designed and implemented by applying the proposed DM scheme into real optical transmission links. Also, it is confirmed that the advantageous duty cycle of RZ is 0.5 and RDPS is setting to be small value for the effective transmitting wide signal wavelength range in optical links with optimal NRD controlled by only one fiber span.

• The Journal of the Acoustical Society of Korea
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• v.16 no.1
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• pp.81-87
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• 1997

In this paper, a new pre-processing method for the recognition of single vowels by use of spectrum envelope is presented. We use new extraction method of a spectrum envelope using the diffusion filter bank. By dividing analysis band of a diffusion filter bank into subbands, we decreased the number of diffusion process. And, by increasing the number of difference, we got higher selectivity. As a result of them, we reduced the total processing time, and got higher enhancement of discrimination. By getting 88.3% of average recognition rate for single vowels of natural voice through computer simulation. We confirmed it to be useful for speech recognition which use spectrum analysis of the voice signal to have many frequency components.

• The Transactions of the Korean Institute of Electrical Engineers D
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• v.52 no.8
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• pp.443-451
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• 2003

Many attempts have been made for the health and lives of patients at a remote site. but little attention has been given to emergency system using wireless or other intelligent networks. In this paper, shown is a remote emergency system which can be used in an ambulance. It possibly gives a great help to the patients who may lose their lives, in other words, gives pre-hospital cure to them being sent to the hospital. Doctors or specialists are able to give a quick help which may give a new life to patients. This system deal with very important patient's data-ECG, SpO$_2$, blood pressure, biomedical signal data etc. - as other emergency system. A good performance better than other system is many but shortly spoken as follows. First, this system is user friendly system activated in windows 2000 environment. Second, MPEG4 and ECG data sent to the other station for specilists can give a pre-hospital cure to patients in advance. Third, there exist effective algorithms to operate this system. Fourth, this system has been made with software mostly, so this system can be easily embedded in IBM compatible computer. In addition to this performance, for the better and reliable system, various tests were proceeded and recursively tested. Tests were made in EV-DO wireless network and Local Area Network. This mobile-fixed remote emergency system using wireless network like EV-DO network will give a great usage to needed area.

• Animal cells and systems
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• v.15 no.2
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• pp.95-106
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• 2011

The transient receptor potential vanilloid 4 (TRPV4) cation channel, a member of the TRP vanilloid subfamily, is expressed in a broad range of tissues. Nitric oxide (NO) as a gaseous signal mediator shows a variety of important biological effects. In many instances, NO has been shown to exhibit its activities via a protein S-nitrosylation mechanism in order to regulate its protein functions. With functional assays via site-directed mutagenesis, we demonstrate herein that NO induces the S-nitrosylation of TRPV4 $Ca^{2+}$ channel on the $Cys^{853}$ residue, and the S-nitrosylation of $Cys^{853}$ reduced its channel sensitivity to 4-${\alpha}$ phorbol 12,13-didecanoate and the interaction between TRPV4 and calmodulin. A patch clamp experiment and $Ca^{2+}$ image analysis show that the S-nitrosylation of $Cys^{853}$ modulates the TRPV4 channel as an inhibitor. Thus, our data suggest a novel regulatory mechanism of TRPV4 via NO-mediated S-nitrosylation on its $Cys^{853}$ residue.

• Journal of Chest Surgery
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• v.56 no.2
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• pp.67-74
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• 2023

Perioperative treatment with conventional cytotoxic chemotherapy for resectable non-small cell lung cancer (NSCLC) has proven clinical benefits in terms of achieving a higher overall survival (OS) rate. With its success in the palliative treatment of NSCLC, immune checkpoint blockade (ICB) has now become an essential component of treatment, even as neoadjuvant or adjuvant therapy in patients with operable NSCLC. Both pre- and post-surgery ICB applications have proven clinical efficacy in preventing disease recurrence. In addition, neoadjuvant ICB combined with cytotoxic chemotherapy has shown a significantly higher rate of pathologic regression of viable tumors compared with cytotoxic chemotherapy alone. To confirm this, an early signal of OS benefit has been shown in a selected population, with programmed death ligand 1 expression ≥50%. Furthermore, applying ICB both pre- and post-surgery enhances its clinical benefits, as is currently under evaluation in ongoing phase III trials. Simultaneously, as the number of available perioperative treatment options increases, the variables to be considered for making treatment decisions become more complex. Thus, the role of a multidisciplinary team-based treatment approach has not been fully emphasized. This review presents up-to-date pivotal data that lead to practical changes in managing resectable NSCLC. From the medical oncologist's perspective, it is time to dance with surgeons to decide on the sequence of systemic treatment, particularly the ICB-based approach, accompanying surgery for operable NSCLC.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.46 no.11
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• pp.66-76
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• 2009

The motion estimation in video encoding system occupies the biggest part. So, we require the motion estimator with efficient structure for real-time operation. And for motion estimator's implementation, it is desired to design hardware module of an exclusive use that perform the encoding process at high speed. This paper proposes motion estimation detection block(MED), 41 SADs(Sum of Absolute Difference) calculation block, minimum SAD calculation and motion vector generation block based on parallel processing. The parallel processing can reduce effectively the amount of the operation. The minimum SAD calculation and MED block uses the pre-computation technique for reducing switching activity of the input signal. It results in high-speed operation. The MED and 41 SADs calculation blocks are composed of adder tree which causes the problem of critical path. So, the structure of adder tree has changed the most commonly used ripple carry adder(RCA) with carry skip adder(CSA). It enables adder tree to operate at high speed. In addition, as we enabled to easily control key variables such as control signal of search range from the outside, the efficiency of hardware structure increased. Simulation and FPGA verification results show that the delay of MED block generating the critical path at the motion estimator is reduced about 19.89% than the conventional strukcture.

• ETRI Journal
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• v.27 no.3
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• pp.312-318
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• 2005

Mid-span spectral inversion (MSSI) has to utilize high optical pump power, for its operation principle is based on a nonlinear optical wavelength conversion. In this paper, a low pump-power operation of MSSI-based chromatic dispersion compensation (CDC) has been achieved successfully, for the first time to our knowledge, by introducing a noise pre-reduction scheme in cascaded wavelength conversions with periodically poled $LiNbO_3$ waveguides at a relatively low operation temperature. As preliminary studies, phase-matching properties and operation-temperature dependence of the wavelength converter (WC) were characterized. The WC pumped at 1549 nm exhibited a wide conversion bandwidth of 59 nm covering the entire C-band and a conversion efficiency of -23.6 dB at 11 dBm pump power. CDC experiments were implemented with 2.5 and 10 Gb/s transmission systems over 100 km single-mode fiber. Although it is well-known that the signal distortion due to chromatic dispersion is not critical at a 2.5 Gb/s transmission, the clear recovery of eye patterns was identified. At 10 Gb/s transmission experiments, eye patterns were retrieved distinctly from seriously distorted ones, and notable improvements in bit-error rates were acquired at a low pump power of 14 dBm.

• International Journal of Internet, Broadcasting and Communication
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• v.12 no.4
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• pp.71-82
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• 2020

Traffic accidents due to excessive speed frequently occur in places where traffic signal controllers are installed, places where sharp curves exist, or places where the traffic signal cycle does not match the current time. These traffic accidents cause economic loss due to the destruction of road facilities and structures, and cause a big problem of increasing the number of traffic accident deaths. When a traffic accident occurs, leaving a tire mark before or after a car crash, pre-collision speed of the car is calculated using the law of conservation of momentum or the skid mark formula. In the skip skid mark generated in ABS brake vehicles and the combshaped yaw mark generated by tire trace caused by lateral sliding, there is a difference of 30-40% in the reliability of the vehicle speed calculated by the smite mark. In this paper, we propose an algorithm that can improve the calculation reliability in vehicle speed by using skid marks in order to compensate for this problem. In addition, we present an intelligent speed calculation algorithm for traffic safety and a computer simulation in order to prevent traffic accidents by estimating the speed of a vehicle, using Skid marks, Yaw marks, and ABS brake characteristics and fuzzy rules.

• Journal of the Institute of Electronics and Information Engineers
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• v.52 no.5
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• pp.214-221
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• 2015

In this paper, we present robust estimation and detection algorithms for discrete-time switched linear systems whose output measurements are corrupted by noises. First, a mode estimation algorithm is proposed based on the minimum distance criterion. Then, state variables are also observed under the active mode estimate. Second, a detection algorithm is constructed to detect the mode switching of the switched system. With the boundedness of measurement noise, the proposed estimation algorithm returns the exact active mode and approximate state information of the switched system. In addition, the detection algorithm can detect the switching time within a pre-determined time interval after the actual switching occurred.