• Journal of the Microelectronics and Packaging Society
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• v.11 no.2 s.31
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• pp.11-16
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• 2004

Electronic devices are getting smaller due to integration of electronic chip, and heat generated in electronic devices can cause loss of performance and/or reliability of the devices. In this research, metals such as gold, nickel and copper are plated onto a porous membrane by electroless plating method to make an efficient micro-heatsinks. Electroless plating includes sensitization and activation steps in pre-treatment steps. A polycarbonate(PC) membrane was sensitizied, activated and deposited in each metal solution for plating. Among manufactured microfibrils, heat transfer and radiation properties of Ni-microfibril with high surface area were more effective than those of $Au^-$ and Cu-microfibril.

• BMB Reports
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• v.35 no.1
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• pp.28-40
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• 2002

Apoptosis is a mode of cell death that plays an important role in both pathological and physiological processes. Research during the last decade has delineated the entire machinery needed for cell death, and its constituents were found to pre-exist in cells. The apoptotic cascade is triggered when cells are exposed to an apoptotic stimulus. It has been known for several years that inhibitors of protein synthesis can potentiate apoptosis that is induced by cytokines and other inducers. Until 1996, it was not understood why protein synthesis inhibitors potentiate apoptosis. Then three reports appeared that suggested the role of the transcription factor NF-${\kappa}B$ activation in protecting the cells from TNF-induced apoptosis. Since then several proteins have been identified that are regulated by NF-${\kappa}B$ and are involved in cell survival, proliferation, and protection from apoptosis. It now seems that when a cell is attacked by an apoptotic stimulus, the cell responds first by activating anti-apoptotic mechanisms, which mayor may not be followed by apoptosis. Whether or not a cell undergoes proliferation, the survival, or apoptosis, appears to involve a balance between the two mechanisms. Inhibitors of protein synthesis seem to suppress the appearance of protein that are involved in anti-apoptosis. The present review discusses how NF-${\kappa}B$ controls apoptosis.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 1998.04a
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• pp.44-56
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• 1998

Effects of the music and white noise on recovery of the autonomic and cortical responses evoked by aversive visual stimulation were analyzed in 20 subjects. It was suggested that the music is able to exert modulatory influence on the physiological activity resulted from exposure to unpleasant IAPS based stimuli. Spectral power of DDG, heart rate(HR)respiration rate (RSR) and electrodermal activity(EDA)were recorded and analyzed for each experimental condition. It was observed HR and RSR deceleration, increased EDA and electrocortical activation expressed in decreased alpha power and increase of delta activity ao occipital and frontal areas. Obtained results suggest that audutory stimulation both with pleasant and sad music lead to restoration of pre-stimulation activation levels of most physiological parameters during listenning to music and in post-stimulation period. White noise evoked short-term physiological responses typical for orienting reaction and quite distinct from changes produced by music. Available data to differentiate effeces among pleasant and sad music, due toqualitative similarities of physilolgical patterns, but suppert an assumption that music is capable to facilitate the process of recovery of physilolgical responses elicited by visual stimulation of negative valence, thus positively modulate post-stress state.

• KSBB Journal
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• v.25 no.6
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• pp.507-512
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• 2010

In this study, we investigated the ability of luteolin, a plant derived flavonoid on hepatocarcinoma cell growth using HepG2 cell culture system. We found that luteolin increased the Smac/DIABLO releases, a mitochondrial protein that potentiates apoptosis. Luteolin also induced either transcriptional activity or expression of PPAR-gamma, a target of cancer growth that PPAR-gamma agonist sensitizes to apoptosis in certain cancer types. To find the possible upstream target molecules of PPAR-gamma activated by luteolin treatment, we used compound C, a specific inhibitor of AMP-activated protein kinase. Pre-treatment of Compound C significantly restored the activation or expression of PPAR-gamma stimulated by luteolin. This result indicated that AMPK signaling might be involved in the activation or expression of PPAR-gamma signaling pathway stimulated by luteolin. Moreover, we also found that luteolin inhibited the insulin-stimulated Akt phosphorylation as well as AICAR, a specific AMPK activator. These results propose that luteolin significantly induces cancer cell death through modulating survival signal pathways such as PPAR-gamma and Akt. AMPK signaling pathway may be an upstream regulator for survival signal pathways such as PPAR-gamma and Akt stimulated by luteolin.

• Journal of the Korean Society of Physical Medicine
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• v.14 no.1
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• pp.111-119
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• 2019

PURPOSE: The aim of this study was to determine how biofeedback training with Shaker exercise effects the activation of the cervical myocardial muscle in stroke with swallowing disorder. METHODS: From June 2018 to September 2018, 30 patients who were hospitalized at C hospital and K hospital in Daegu, and K hospital in Gumi were surveyed to meet the criteria for selection. The participants were classified into three groups, and Shaker exercise was applied three times a day, five times a week, for four weeks; visuoauditory biofeedback group (VABG), visual biofeedback group (VBG), and self-exercises group (SG). In addition, the suprahyoid muscle activity was performed three times (before intervention, after intervention, and after two weeks). RESULTS: The pre and post-test comparisons, revealed a significant difference between the three groups (p<.01); VABG had the highest suprahyoid muscle activity. The post-test and follow-up test produced similar results in, the three groups (p>.05). The mean comparison showed the smallest difference in VABG, indicating that muscle persistence was the best. CONCLUSION: Shaker exercise has an effect on suprahyoid muscle activation. Biofeedback training, which provides an input of multi-sensory information in swallowing disorder treatment is recommended because it has the greatest effect when combined with visuoauditory biofeedback.

• Nuclear Engineering and Technology
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• v.51 no.3
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• pp.746-754
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• 2019

Vitrification of radioactive liquid waste (RLW) provides a feasible solution for isolating radionuclides from the biosphere for an extended period. In vitrification, base glass and radioactive waste are added simultaneously into the melter. Determination of heat and mass transfer rates is necessary for rational design and sizing of melter. For obtaining an assured product quality, knowledge of reaction kinetics associated with the thermal decomposition of waste constituents is essential. In this study Thermogravimetry (TG) - Differential Thermogravimetry (DTG) of eight kinds of nitrates and two oxides, which are major components of RLW, is investigated in the temperature range of 298-1273 K in the presence of base glasses of five component (5C) and seven component (7C). Studies on thermal behavior of constituents in RLW were carried out at heating rates ranging from 10 to $40\;K\;min^{-1}$ using TG - DTG. Thermal behavior and related kinetic parameters of waste constituents, in the presence of 5C and 7C base glass compositions were also investigated. The activation energy, pre-exponential factor and order of the reaction for the thermal decomposition of 24% waste oxide loaded glasses were estimated using Kissinger method.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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• v.26 no.2
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• pp.55-61
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• 2020

Background: This study demonstrate the effect of bridge exercise using sling device on the improvement of gluteal maximus and elector Spine EMG (electromyogram) in college student. Methods: 30 college students participated in this experiment and received bridge exercise using sling device for 30 minutes a day for four weeks. Results: The effects of bridge exercise using sling device were evaluated by measuring the muscle activation on gluteal maximus and elector spine. The differences between pre-test and post-test in G-max (p<.05) and right elector spine (p<.05) were significant. The difference between in G-max left and right side was not significant both before (p<.05) and after (p<.05) bridge exercise using sling. The difference between in elector spine left and right side was not significant before bridge exercise using sling (p<.05) but after bridge exercise using sling (p<.05). Conclusion: The results indicated that bridge exercise using sling device improved gluteal maximus and elector spine EMG. This study demonstrated the effectiveness of this new approach and provided a good guide to improve gluteal maximus and elector spine EMG.

• The Journal of Korean Physical Therapy
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• v.33 no.2
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• pp.106-113
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• 2021

Purpose: This study examined the effectiveness of action observation training (AOT) and mirror therapy in improving the electroencephalograms (EEG) of stroke patients. Methods: Patients were allocated randomly to three groups: an action observation training with activity (AOTA) group (n=12), a mirror therapy with activity (MTA) group (n=11), and an AOT-only group (n=12). All groups received conventional physiotherapy in five 60-minute sessions over six weeks. The AOTA, MTA, and AOT groups practiced AOTA, MTA, and AOT, respectively, in three 30-minute sessions over six weeks. The differences between the pre- and post-treatment EEGs were assessed using a paired t-test. Comparisons between the groups were performed using one-way ANOVA. Results: The participants in the AOTA and MTA groups showed significant improvement in the EEG. AOTA improved the alpha waves of the prefrontal, temporal, and parietal lobes significantly (p<0.05). MTA improved the alpha waves of the temporal lobe significantly (p<0.05). AOT did not result in significant improvement Conclusion: AOTA and MTA improve stroke patients' EEGs. Mirror neuron activation combined with conventional stroke physiotherapy promotes motor recovery and functioning. The effect is enhanced when the actions are executed after observation. Further research into mirror neuron activation will be needed to develop methods to improve the EEGs of stroke patients.

• Journal of the Korean Society of Physical Medicine
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• v.18 no.3
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• pp.65-72
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• 2023

PURPOSE: This study assessed the influence of bilateral coordination exercises on unstable support surfaces on leg muscle activation and balance in stroke patients. METHODS: Two groups were recruited for comparison: an experimental group of 10 individuals who performed bilateral coordination exercises on unstable surfaces and a control group of 10 individuals who performed the same exercises on stable surfaces. All participants were assigned randomly. Pre-tests were conducted to measure the leg muscle activation and balance levels of the participants prior to the experiment. The intervention was comprised of three 30-minute weekly sessions for four weeks, followed by a post-test after the four-week period. RESULTS: Significant differences were identified within the experimental group in relation to all muscles (p < .01) and balance (p < .05). Within the control group, significant differences were identified in relation to the rectus femoris muscle, biceps femoris muscle, and balance (p < .05). Significant differences between the two groups were only observed in relation to the tibialis anterior and soleus muscles (p < .05). CONCLUSION: Only the tibialis anterior and soleus muscles showed significant differences between the two groups. This effectiveness may be attributed to using an ankle strategy to maintain body balance during exercise on unstable surfaces.

• Journal of Information Processing Systems
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• v.19 no.5
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• pp.614-630
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• 2023

Dead trees significantly impact forest production and the ecological environment and pose constraints to the sustainable development of forests. A lightweight YOLOv4 dead tree detection algorithm based on unmanned aerial vehicle images is proposed to address current limitations in dead tree detection that rely mainly on inefficient, unsafe and easy-to-miss manual inspections. An improved logarithmic transformation method was developed in data pre-processing to display tree features in the shadows. For the model structure, the original CSPDarkNet-53 backbone feature extraction network was replaced by MobileNetV3. Some of the standard convolutional blocks in the original extraction network were replaced by depthwise separable convolution blocks. The new ReLU6 activation function replaced the original LeakyReLU activation function to make the network more robust for low-precision computations. The K-means++ clustering method was also integrated to generate anchor boxes that are more suitable for the dataset. The experimental results show that the improved algorithm achieved an accuracy of 97.33%, higher than other methods. The detection speed of the proposed approach is higher than that of YOLOv4, improving the efficiency and accuracy of the detection process.