• Journal of the Institute of Electronics Engineers of Korea SD
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• v.45 no.9
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• pp.8-13
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• 2008

Noise in homogeneous extrinsic semiconductor samples is calculated due to distributed diffusion noise sources. As the length of the device shrinks at a fixed bias voltage, the ac-wise short-circuit noise current shows excess noise as well as thermal noise spectra. This excess noise behaves like a full shot noise when the channel length becomes very small compared with the extrinsic Debye length. For the first time, the analytic formula of the excess noise in extrinsic semiconductors from velocity-fluctuation noise sources is given for finite frequencies. This formula shows the interplay between transit time, dielectric relaxation time, and velocity relaxation time in determining the terminal noise current as well as the carrier density fluctuation. As frequency increases, the power spectral density of the excess noise rolls off. This formula sheds light on noise in nanoscale MOSFETs where quasi-ballistic transport plays an important role in carrier transport and noise.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.11 no.3
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• pp.1633-1649
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• 2017

In remote sensing image processing, the traditional fusion algorithm is based on the Intensity-Hue-Saturation (IHS) transformation. This method does not take into account the texture or spectrum information, spatial resolution and statistical information of the photos adequately, which leads to spectrum distortion of the image. Although traditional solutions in such application combine manifold methods, the fusion procedure is rather complicated and not suitable for practical operation. In this paper, an improved IHS transformation fusion algorithm based on the local variance weighting scheme is proposed for remote sensing images. In our proposal, firstly, the local variance of the SPOT (which comes from French "Systeme Probatoire d'Observation dela Tarre" and means "earth observing system") image is calculated by using different sliding windows. The optimal window size is then selected with the images being normalized with the optimal window local variance. Secondly, the power exponent is chosen as the mapping function, and the local variance is used to obtain the weight of the I component and match SPOT images. Then we obtain the I' component with the weight, the I component and the matched SPOT images. Finally, the final fusion image is obtained by the inverse Intensity-Hue-Saturation transformation of the I', H and S components. The proposed algorithm has been tested and compared with some other image fusion methods well known in the literature. Simulation result indicates that the proposed algorithm could obtain a superior fused image based on quantitative fusion evaluation indices.

• Journal of the Korean Institute of Telematics and Electronics
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• v.26 no.6
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• pp.48-56
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• 1989

Contact-type linear image sensors for facsimile have been fabricated by means of rf glow discharge decomposition method of silane. The dependence of their electrical and optical properties on rf power, $SiH_4$ flow rate, ambient gas pressure, $H_2SiH_4$ ratio and substrate temperature are described. The a-Si:H monolayer demonstriated photosensitivity of 0.85 and $I_{ph}/I_d$ ratio of 100 unger 100 lux illumination. However, this monolayer has relatively high dark current due to carrier injection from both electrodes, resulting in low $I_{ph}/I_{dd}$ ratio. To suppress the dark current we have fabricated $SiO_2/i-a-Si:H/p-a-Si:H:B$ multilayer film with blocking structure. The photocurrent of this multilayer sensor with 6 V bias became saturated ar about 20nA under 10 lux illumination, while the dark current was less than 0.2 nA. Moreover, the spectral sensitivity of the multilayer film was enhanced for short wavelength visible region, compared with that of the a-Si:H monolayer. These results show that the fabricated photocon-ductive film can be used as the linear image sensor of the facsimile.

• Molecules and Cells
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• v.37 no.12
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• pp.888-898
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• 2014

Pancreatic cancer is one of the most fatal cancers and is associated with limited diagnostic and therapeutic modalities. Currently, gemcitabine is the only effective drug and represents the preferred first-line treatment for chemotherapy. However, a high level of intrinsic or acquired resistance of pancreatic cancer to gemcitabine can contribute to the failure of gemcitabine treatment. To investigate the underlying molecular mechanisms for gemcitabine resistance in pancreatic cancer, we performed label-free quantification of protein expression in intrinsic gemcitabine-resistant and -sensitive human pancreatic adenocarcinoma cell lines using our improved proteomic strategy, combined with filter-aided sample preparation, single-shot liquid chromatography-mass spectrometry, enhanced spectral counting, and a statistical method based on a power law global error model. We identified 1931 proteins and quantified 787 differentially expressed proteins in the BxPC3, PANC-1, and HPDE cell lines. Bioinformatics analysis identified 15 epithelial to mesenchymal transition (EMT) markers and 13 EMT-related proteins that were closely associated with drug resistance were differentially expressed. Interestingly, 8 of these proteins were involved in glutathione and cysteine/methionine metabolism. These results suggest that proteins related to the EMT and glutathione metabolism play important roles in the development of intrinsic gemcitabine resistance by pancreatic cancer cell lines.

• Korean Journal of Biological Psychiatry
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• v.20 no.4
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• pp.119-128
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• 2013

Objectives Memory impairment is a very important mental health issue for elderly and adults. Mild cognitive impairment (MCI) is a prodromal stage of Alzheimer's disease (AD). Early detection of the prodromal stage of patients with AD is an important topic of interest for both mental health clinicians and policy makers. Methods Electroencephalograpgy (EEG) has been used as a possible biological marker for patients with MCI, and AD. In this review, we will summarize the clinical implications of EEG and ERP as a biological marker for AD and MCI. Results EEG power density, functional coupling, spectral coherence, synchronization, and connectivity were analyzed and proved their clinical efficacy in patients with the prodromal stage of AD. Serial studies on late event-related potentials (ERPs) were also conducted in MCI patients as well as healthy elders. Even though these EEG and ERP studies have some limitations for their design and method, their clinical implications are increasing rapidly. Conclusion EEG and ERP can be used as biological markers of AD and MCI. Also they can be used as useful tools for early detection of AD and MCI patients. They are useful and sensitive research tools for AD and MCI patients. However, some problems remain to be solved until they can be practical measures in clinical setting.

• Wind and Structures
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• v.31 no.3
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• pp.269-285
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• 2020

The statistical characteristics of typhoon wind speed records tend to have a considerable time-varying trend; thus, the stationary wind model may not be appropriate to estimate the wind characteristics of typhoon events. Several nonstationary wind speed models have been proposed by pioneers to characterize wind characteristics more accurately, but comparative studies on the applicability of the different wind models are still lacking. In this study, three landfall typhoons, Ampil, Jongdari, and Rumbia, recorded by ultrasonic anemometers atop the Shanghai World Financial Center (SWFC), are used for the comparative analysis of stationary and nonstationary wind characteristics. The time-varying mean is extracted with the discrete wavelet transform (DWT) method, and the time-varying standard deviation is calculated by the autoregressive moving average generalized autoregressive conditional heteroscedasticity (ARMA-GARCH) model. After extracting the time-varying trend, the longitudinal wind characteristics, e.g., the probability distribution, power spectral density (PSD), turbulence integral scale, turbulence intensity, gust factor, and peak factor, are comparatively analyzed based on the stationary wind speed model, time-varying mean wind speed model and time-varying standard deviation wind speed model. The comparative analysis of the different wind models emphasizes the significance of the nonstationary considerations in typhoon events. The time-varying standard deviation model can better identify the similarities among the different typhoons and appropriately describe the nonstationary wind characteristics of the typhoons.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.10 no.4
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• pp.1481-1500
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• 2016

Device-to-Device (D2D) communication underlaying macro-small cell networks, as one of the promising technologies in the era of 5G, is able to improve spectral efficiency and increase system capacity. In this paper, we model the cross- and co-tier D2D communications in two-tier macro-small cell networks. To avoid the complicated interference for cross-tier D2D, we propose a mode selection scheme with a dedicated resource sharing strategy. For co-tier D2D, we formulate a joint optimization problem of power control and resource reuse with the aim of maximizing the overall outage capacity. To solve this non-convex optimization problem, we devise a heuristic algorithm to obtain a suboptimal solution and reduce the computational complexity. System-level simulations demonstrate the effectiveness of the proposed method, which can provide enhanced system performance and guarantee the quality-of-service (QoS) of all devices in two-tier macro-small cell networks. In addition, our study reveals the high potential of introducing cross- and co-tier D2D in small cell networks: i) cross-tier D2D obtains better performance at low and medium small cell densities than co-tier D2D, and ii) co-tier D2D achieves a steady performance improvement with the increase of small cell density.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.7 no.8
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• pp.1911-1932
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• 2013

Orthogonal frequency-division multiplexing (OFDM) has become a popular modulation scheme for wireless protocols because of its spectral efficiency and robustness against multipath interference. Although the components of various OFDM protocols are functionally similar, they remain distinct because of the characteristics of the environment. Recently, graphics processing units (GPUs) have been used to accelerate the signal processing of the physical layer (PHY) because of their great computational power, high development efficiency, and flexibility. In this paper, we describe the implementation of parameterized baseband modules using GPUs for two different OFDM protocols, namely, 802.11a and 802.16. First, we introduce various modules in the modulator/demodulator parts of the transmitter and receiver and analyze the computational complexity of each module. We then describe the integration of the GPU-based baseband modules of the two protocols using the parameterized method. GPU-based implementations are addressed to explain how to accelerate the baseband processing to archive real-time throughput. Finally, the performance results of each signal processing module are evaluated and analyzed. The experiments show that the GPU-based 802.11a and 802.16 PHY meet the real-time requirement and demonstrate good bit error ratio (BER) performance. The performance comparison indicates that our GPU-based implemented modules have better flexibility and throughput to the current ones.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.35 no.2A
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• pp.202-208
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• 2010

The performance of upstream transmission in SCM-PON is generally limited by the presence of OBI which is caused by the beating of two or more lasers. In this paper, we propose a novel approach for reducing OBI problem by using heterodyne detection with an additional LD as a local oscillator, resulting that the RF signal is shifted to the other spectal band. In addition, it is possible that the proposed method can provide the cost-effective solution thanks to the loop-back mechanism using R-SOA in ONUs. The performance is superior when the spectral width of LD is smaller and the power difference between the transmission LD and the oscillation LD is bigger. System configuration and design consideration are discussed. Performance of the systems is evaluated by simulator called OptSim. It is expected to provide WDM/SCM-PON system not only cost-effective but also efficient in increasing the number of subscribers.

• Geomechanics and Engineering
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• v.21 no.2
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• pp.179-186
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• 2020

Investigating damage potential of the railway infrastructure requires either large amount of case histories or in-depth numerical analyses, or both for which large amounts of effort and time are necessary to accomplish thoroughly. Rather than performing comprehensive studies for each damage case, in this study we collect and analyze a case history of the high-speed railway system damaged by the 2004 M6.6 Niigata Chuetsu earthquake for the development of the seismic fragility curve. The development processes are: 1) slice the railway system as 200 m segments and assigned damage levels and intensity measures (IMs) to each segment; 2) calculate probability of damage for a given IM; 3) estimate fragility curves using the maximum likelihood estimation regression method. Among IMs considered for fragility curves, spectral acceleration at 3 second period has the most prediction power for the probability of damage occurrence. Also, viaduct-type structure provides less scattered probability data points resulting in the best-fitted fragility curve, but for the tunnel-type structure data are poorly scattered for which fragility curve fitted is not meaningful. For validation purpose fragility curves developed are applied to the 2016 M7.0 Kumamoto earthquake case history by which another high-speed railway system was damaged. The number of actual damaged segments by the 2016 event is 25, and the number of equivalent damaged segments predicted using fragility curve is 22.21. Both numbers are very similar indicating that the developed fragility curve fits well to the Kumamoto region. Comparing with railway fragility curves from HAZUS, we found that HAZUS fragility curves are more conservative.